Indian Journal of Tuberculosis最新文献

{"title":"A rare case report of multi-organ tuberculosis presenting as cerebritis","authors":"Bang Ngoc Dao ,&nbsp;Thang Ba Ta ,&nbsp;Lam Nguyen ,&nbsp;Minh Tuan Ngo ,&nbsp;Bac Thanh Nguyen ,&nbsp;Tuan Cong Duong ,&nbsp;Hien Thi Dieu Le ,&nbsp;Dung Tien Nguyen","doi":"10.1016/j.ijtb.2024.11.006","DOIUrl":"10.1016/j.ijtb.2024.11.006","url":null,"abstract":"<div><div>Tuberculosis (TB) in multiple organs, especially central nervous system TB (brain abscess due to TB), often occurs in patients with severe immunodeficiency, related to HIV infection, organ transplantation, etc., rarely seen in clinical practice. Due to the complexity of the variation, prediction and treatment are difficult. Only predictive testing and necessary treatment solutions must be based on the specific state of the disease. In addition to anti-TB antibiotic therapy, addressing symptoms and implementing preventive measures are crucial for successful treatment outcomes in patients.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S98-S101"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial patterns and multilevel analysis of factors associated with paediatric tuberculosis in India","authors":"Mohan Balakrishnan,&nbsp;Varadharajan R","doi":"10.1016/j.ijtb.2024.04.014","DOIUrl":"10.1016/j.ijtb.2024.04.014","url":null,"abstract":"<div><h3>Background</h3><div>Tuberculosis (TB) is a serious global health problem that remains as leading cause of high mortality and morbidity in children. Despite India<span> with a high global tuberculosis burden, very few studies have specifically addressed the problem of TB among children, a vulnerable group where delayed diagnosis aggravates the morbidity.</span></div></div><div><h3>Methods</h3><div><span><span>Identifying the hotspots with high risk of Paediatric<span> TB by employing a localized clustering method can help in developing </span></span>regional policies for eliminating TB. Factors specified at various levels must be taken into account in studies of health aetiology and their practical applications for disease control. </span>Multilevel analysis<span> is a viable analytic technique for including components identified at many levels in an epidemiologic study and the interindividual variances can be inferred using multilevel analysis.</span></div></div><div><h3>Results</h3><div>In this study, the incidence of tuberculosis pertaining to individual-level attributes are elucidated at district and state level through a multilevel model using the information from National Family Health Survey-5, carried out in 2019–20 comprising 636,699 households over 28 states and 8 union territories of India and the spatial method has detected 62 hotspots.</div></div><div><h3>Conclusion</h3><div>The model expresses a nested structure with districts and states having significant contribution in the variation of paediatric TB and the autocorrelation pattern exhibited by the hotspots emphasises the need for targeted TB elimination programs.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S12-S17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact Assessment of Covid19 pandemic on operational aspect of national tuberculosis elimination program in Bhavnagar district","authors":"Bansi Trivedi ,&nbsp;Jigna Dave","doi":"10.1016/j.ijtb.2024.05.012","DOIUrl":"10.1016/j.ijtb.2024.05.012","url":null,"abstract":"<div><h3>Purpose</h3><div>India account more than one forth tuberculosis cases. Covid 19 affect health condition like tuberculosis. We aim to assess impact of covid 19 on National Tuberculosis Elimination Program.</div></div><div><h3>Method</h3><div>In depth interviews of district tuberculosis officer, private practitioner and tuberculosis patients (who registered in District Tuberculosis Centre during April 2020–September2020) were conducted in Bhavnagar district. Notification rate during covid 19 was obtained from District Tuberculosis Centre of Bhavnagar district. All interviews were audio-recorded after obtaining written informed consent, transcribed in English, and analyzed in the form of codes and categories.</div></div><div><h3>Result</h3><div>Health care providers perceived covid 19 lockdowns, fear among patients, difficult transportation, diversion of resources and reduced concerns towards tuberculosis were the reason for low notification during the COVID-19 pandemic.</div></div><div><h3>Conclusion</h3><div>COVID-19 lockdown had detrimental effects on notification rate. During such testing time patients felt proper supervision by front line worker, no issued in direct benefit transfer for nutrition support and adequate supply of medicine. Telemedicine, awareness through social media, collaboration with other agencies, bidirectional screening implementation, coping of covid 19 fear among patients, separate tuberculosis facility were the expectation from higher authority if next wave of covid 19 will come. Future studies can evaluate the feasibility, impact, and cost-effectiveness of such interventions.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S28-S33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Gene Xpert MTB/RIF assay for detecting tuberculous spondylitis in specimens obtained by CT-guided aspiration/biopsy and spectrum of imaging findings in spinal tuberculosis","authors":"Richa Misra ,&nbsp;Anil Kumar Singh ,&nbsp;Zafar Neyaz ,&nbsp;Vivek Kumar Singh ,&nbsp;Vimal K. Paliwal ,&nbsp;Prabhakar Mishra","doi":"10.1016/j.ijtb.2023.10.007","DOIUrl":"10.1016/j.ijtb.2023.10.007","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the utility of the GeneXpert MTB/RIF assay for the diagnosis of tuberculous spondylitis in samples obtained by CT-guided aspiration/biopsy. The effect of anti-tubercular treatment, specimen type, and imaging findings on laboratory results was also assessed along with a comparison of imaging findings in tubercular versus non-tubercular cases.</div></div><div><h3>Methods</h3><div><span>This prospective observational study, planned for CT-guided aspiration/ biopsy, included 70 adults with suspected tuberculous spondylitis. Specimens were sent for microscopy, </span>histopathology, TB culture, and Gene Xpert MTB/RIF assay. The correlation of sampling location, specimen type, anti-tubercular treatment, and imaging findings on microbiology results was documented.</div></div><div><h3>Results</h3><div>A definite diagnosis of tuberculous spondylitis was obtained in 50 cases. The assay had a 100 % agreement for smear-positive, culture-positive, specimens while the overall agreement was 41.3 %. Rifampicin resistance was detected in 8 cases. Seventy-one percent of patients were on empiric ATT. Imaging findings such as end plate destruction, paravertebral soft tissue thickening and abscess, disc involvement, sequestrum, and bony fragments were significantly associated with a final diagnosis of spinal tuberculosis.</div></div><div><h3>Conclusions</h3><div>The Gene Xpert MTB/RIF assay performed on specimens obtained by CT-guided aspiration/biopsy is a sensitive and rapid method of establishing a diagnosis of tuberculous spondylitis even in cases on ATT.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 1","pages":"Pages 61-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135372156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of probable post-COVID cardiac sequelae and its health seeking behaviour among health care workers: A cross-sectional analytical study","authors":"Yamini Marimuthu ,&nbsp;Greshma Chandrasekharan Nair ,&nbsp;Umesh Nagesh ,&nbsp;Amal Anand ,&nbsp;Kamal Kishore Chopra ,&nbsp;Bharathnag Nagappa ,&nbsp;Nandini Sharma ,&nbsp;Gopinath Sivashankar ,&nbsp;Neha Nagaraj","doi":"10.1016/j.ijtb.2023.06.008","DOIUrl":"10.1016/j.ijtb.2023.06.008","url":null,"abstract":"<div><h3>Background</h3><div>Post-COVID Sequelae are considered as the signs and symptoms that develop during or after an infection consistent with COVID-19 which continue for more than 12 weeks and are not explained by alternative diagnosis. The prevalence of post-COVID cardiac sequelae ranges from 2% to 71% across the globe and it is reported to be around 22% in India. With this background, the study was conducted to assess the prevalence of probable post-COVID cardiac sequelae (PCCS) and delay in health-seeking for post-COVID cardiac sequelae among healthcare workers.</div></div><div><h3>Methods</h3><div>A facility-based cross-sectional study was conducted among health workers and students in a medical educational institute in Karnataka from May 2022 to July 2022. Health workers and students who had a past history of COVID-19 during the COVID pandemic were included in the study. Socio-demographic details, clinical profile, symptoms of post-COVID cardiac sequelae, and health-seeking behavior were collected. Data were collected in Epicollect5 and analyzed using STATA statistical software. The prevalence of probable PCCS was expressed with 95% confidence interval. Univariate binomial logistic regression was done to assess the determinants of probable post-COVID sequelae.</div></div><div><h3>Results</h3><div>A total of 336 health workers were included in the study with a mean (SD) age of 25.6 (8.6) years. A majority (68.2%) of them were females and only 25 (7.4%) belonged to the age group of 45–60 years. The prevalence of probable post-COVID cardiac sequelae among health workers and medical students was 11.9% (95% CI: 8.76–15.7). Among the 40 participants who had probable post-COVID cardiac sequelae, 55% (95% CI: 40%–70%) were not evaluated further which was their treatment-seeking behavior. Females, hypertensive individuals, and those who had moderate-severe disease during acute COVID-19 disease were at higher risk of developing probable post-COVID cardiac sequelae.</div></div><div><h3>Conclusion</h3><div>Around one out of ten individuals had experienced probable post-COVID cardiac sequelae, but only half of them got evaluated for it. An appropriate screening program for post-COVID cardiac sequelae needs to be implemented along with awareness-raising activities about long COVID to prevent the morbidity and mortality associated with it.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 1","pages":"Pages 5-11"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121950242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective evaluation of ethambutol toxic optic neuropathy in patients of pulmonary tuberculosis","authors":"Neharika Sharma ,&nbsp;Abha Gahlot ,&nbsp;Jawahar Lal Goyal ,&nbsp;Devendra Kumar singh ,&nbsp;Divya Singh ,&nbsp;Arushi Gupta ,&nbsp;Pulkit Gandhi","doi":"10.1016/j.ijtb.2023.11.001","DOIUrl":"10.1016/j.ijtb.2023.11.001","url":null,"abstract":"<div><h3>Aim</h3><div>The aim of the study was to evaluate visual parameters for early detection of ethambutol<span> toxicity to prevent irreversible optic nerve damage.</span></div></div><div><h3>Method</h3><div><span>This cohort study included 50 newly diagnosed cases of pulmonary tuberculosis, i.e. 100 eyes, in people aged 18–72 years, who received ethambutol as part of the antitubercular therapy. Before starting antitubercular treatment, at each monthly visit, </span>ophthalmic<span> examination was done that included best corrected visual acuity, optic disc evaluation, colour vision, contrast sensitivity, pupil cycle time and automated perimetry for a period of six months. Ethambutol was discontinued in patients who showed signs of visual impairment. These patients were observed for another three months for reversibility of toxicity.</span></div></div><div><h3>Results</h3><div>Visual functions were normal in all patients at baseline. Out of 50 patients, 47 didn't show any signs of deterioration in visual functions even after six months of oral administration of ethambutol. However, 3 out of 50 patients, i.e. 6 eyes (6 %), showed signs of toxicity after 4–5 months – LogMAR visual acuity deteriorated from 0.00 to 1.08 (±0.40); mean contrast sensitivity deteriorated from 1.725 (±0.075) to 1.12 (±0.18); mean deviation in visual fields got impaired from −1.37 (±0.15) to −10.93 (±2.66); and colour vision got severely affected. All the affected patients were aged above 65.</div></div><div><h3>Conclusion</h3><div>In the present study, six percent of 50 patients showed ethambutol toxic optic neuropathy. It was concluded that patients should be comprehensively evaluated for visual parameters before starting the ethambutol treatment. They should be closely monitored by an ophthalmologist for visual functions every month to detect ethambutol toxicity at the early reversible stage to prevent irreversible damage to the optic nerve. Patients should be asked to report immediately if they detect any blurring of vision or colour vision abnormality.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 1","pages":"Pages 69-73"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of urogenital tuberculosis in people living with HIV","authors":"Bruno Duque Ramos ,&nbsp;Victor Silvestre Soares Fanni ,&nbsp;André Netto Bastos ,&nbsp;José Murillo Bastos Netto ,&nbsp;André Avarese de Figueiredo","doi":"10.1016/j.ijtb.2024.03.009","DOIUrl":"10.1016/j.ijtb.2024.03.009","url":null,"abstract":"<div><div>The prevalence of urogenital tuberculosis<span><span> (UGT) is not well known, especially in people living with HIV, therefore, our aim was to identify the prevalence of urogenital tuberculosis in HIV-infected individuals and characterize the clinical and laboratory risk factors associated with UGT. A </span>cross sectional study<span><span><span> was conducted to characterize the prevalence of UGT in people living with HIV. PCR tests and specific culture were performed on samples from 181 patients living with HIV, divided into two groups: A) patients with suggestive UGT symptoms and b) hospitalized patients without any suggestive UGT symptoms. Only one case of UGT was diagnosed, with a positive PCR but negative specific culture, resulting in a prevalence of 0.55%. The patient had disseminated tuberculosis (miliary pulmonary, intestinal, and urogenital with bilateral nephromegaly) with acute febrile syndrome, no urogenital symptoms, but with microscopic </span>hematuria<span> and sterile pyuria. This patient had poorly controlled </span></span>HIV infection<span> with positive viral load and CD4 count below 200 cells/mm³. The prevalence of UGT in patients living with HIV is very low. However, patients with poorly controlled disease may present disseminated tuberculosis associated with UGT. Urine screening for UGT may be relevant for diagnosing disseminated tuberculosis in patients living with HIV with acute infectious syndrome.</span></span></span></div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 1","pages":"Pages 83-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Diabetes among tuberculosis patients in Bengaluru is alarming: Time to tackle it efficiently!”","authors":"Shilpa Madhava Kunjathur ,&nbsp;Ronald Jaswanth Kumar Katta ,&nbsp;Sharath Burguina Nagaraja ,&nbsp;Sangeetha M D ,&nbsp;Sreenath Menon P K ,&nbsp;Anil Singarajapure","doi":"10.1016/j.ijtb.2024.09.002","DOIUrl":"10.1016/j.ijtb.2024.09.002","url":null,"abstract":"<div><h3>Context</h3><div>Tuberculosis (TB) remains a major health challenge in India, with the country bearing the highest global burden. Co-existing with this epidemic is the surge in diabetes mellitus (DM) cases, earning India the title of \"Diabetes Capital.\"</div></div><div><h3>Aim</h3><div>This study investigates the association between TB and DM, focusing on the feasibility and outcomes of screening TB patients for diabetes. It also explores the challenges and opportunities for integrated care of TB-DM comorbidities.</div></div><div><h3>Settings</h3><div>and Design: This cross-sectional study was conducted in 32 tuberculosis units in the BBMP district of Bengaluru, Karnataka, India.</div></div><div><h3>Materials and methods</h3><div>Data were collected from TB laboratory registers and through interviews with National Tuberculosis Elimination Program (NTEP) healthcare providers. The study assessed the implementation of diabetes screening, challenges in the process, and suggestions for improvement.</div></div><div><h3>Results</h3><div>As part of the Quantitative data, of the 17,052 presumptive TB cases examined, 41% were aware of their diabetes status. Diabetics constituted 14.61% of the presumptive cases. Of the diagnosed TB patients, 25.2% were found to be positive for DM as well. Qualitatively, healthcare providers highlighted operational challenges, mainly concerning the timing of blood sugar testing and the need for referral to higher-level facilities. They also emphasized the importance of generating awareness among communities and training healthcare workers for on-the-spot diabetes screening.</div></div><div><h3>Conclusion</h3><div>The findings highlight the urgent need for improved screening of TB patients for diabetes, timely initiation of anti-diabetic treatment, and comprehensive healthcare services under one roof. Advocacy, communication, and social mobilization strategies should be intensified to create awareness of TB-DM comorbidities in the general population.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S60-S63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of patients with tuberculosis managed under NTEP through STEPS in a private hospital in India","authors":"Jaisy Thomas,&nbsp;Merin Yohannan,&nbsp;Rajkrishnan Soman Pillai","doi":"10.1016/j.ijtb.2024.03.012","DOIUrl":"10.1016/j.ijtb.2024.03.012","url":null,"abstract":"<div><h3>Objective</h3><div><span>As the global health care commits to the ambitious goal of TB elimination, System for TB Elimination in Private Sector (STEPS) was introduced to provide appropriate standards of </span>TB care to all patients. This study aims to assess the outcome of TB patients treated under STEPS programme in a Private hospital and find any significant factors in determining favourable and unfavourable outcomes.</div></div><div><h3>Setting</h3><div>Private Quaternary care hospital in South India.</div></div><div><h3>Design</h3><div>Retrospective study which included 163 patients diagnosed with Pulmonary and Extra-Pulmonary Tuberculosis from January 2020 to June 2022. Details like clinical profile, type and site of tuberculosis, modification of ATT regimen, adverse effects and outcomes were recorded.</div></div><div><h3>Results</h3><div>The study population included 62.6% males. 45.3% had Type-2 Diabetes mellitus. More than half of the cases were Extra-Pulmonary TB (52.2%) and 54.6% had microbiological confirmation. The Cure Rate in Pulmonary and Extra-Pulmonary TB cases were 76.7% and 79.2% respectively. 29 patients expired during TB treatment out of which 41.3% had renal failure. Advanced age and chronic kidney disease as a co-morbidity were significant in causing unfavourable outcomes.</div></div><div><h3>Conclusion</h3><div>Proper implementation of STEPS can help in 100% TB notification and effective care of TB patients.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S18-S22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of post-pulmonary tuberculosis sequelae and its management in a tertiary care facility in South India","authors":"Swathy Govindaswamy ,&nbsp;Venugopal Jaganathan ,&nbsp;Abdul kadhar Sathick Batcha ,&nbsp;Mowfiya Nazeer ,&nbsp;Simran Ravichandran ,&nbsp;Swetha Balasubramaniyam","doi":"10.1016/j.ijtb.2024.10.008","DOIUrl":"10.1016/j.ijtb.2024.10.008","url":null,"abstract":"<div><h3>Background</h3><div>Post-pulmonary Tuberculosis (PTB) sequelae are chest alterations caused by pulmonary tuberculosis problems, even after treatment and infection elimination. These alterations can cause pulmonary dysfunction, ranging from mild irregularities to acute dyspnea, increasing the risk of respiratory-related deaths. Current research aims to investigate the type, severity, clinical management, and impact on quality of life in affected individuals.</div></div><div><h3>Materials and methods</h3><div>A prospective observational study with 66 patients was carried out in a South Indian tertiary care facility. We gathered sociodemographic and clinical data from the patients. Imaging investigations (chest X-ray, CT scans) and pulmonary function test reports (Spirometry) were used to assess the post-pulmonary TB sequelae. The patient's quality of life was evaluated using the WHOQoL-BREF questionnaire.</div></div><div><h3>Results</h3><div>Out of 66 patients, 66.7% were men, and the average age was 57.2 years. According to radiological analysis, most patients had airway difficulties (38%), followed by parenchymal problems (36.3%). Obstruction was the most typical abnormality identified (81.9%). Bronchodilators, LABA + ICS, SABA, leukotriene antagonists, antibiotics, and other fixed medications treat post-PTB sequelae. Substantial impairment was observed in quality of life.</div></div><div><h3>Conclusion</h3><div>Patients who have had pulmonary TB are prone to post-TB respiratory symptoms and sequelae. The quality of life noticeably declined. This study's findings underscore the importance of robust, evidence-based guidelines and practical implementation techniques for managing post-pulmonary TB.</div></div>","PeriodicalId":39346,"journal":{"name":"Indian Journal of Tuberculosis","volume":"72 ","pages":"Pages S75-S79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}