Asian Journal of Pediatric Research最新文献

{"title":"Overview of the Most Prevalent Pediatric Congenital Heart Diseases: A Literature Review","authors":"Hala Fawzy Sale Elsedawy","doi":"10.9734/ajpr/2023/v13i4308","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4308","url":null,"abstract":"Like every other prevalent disease process, cardiovascular diseases pose a great risk for the morbidity and mortality of human beings. Pediatric cardiovascular disease (CVD) represents a broad spectrum of disorders that affect both the heart and blood vessels in the pediatric population. There have been several epidemiological studies done to highlight the prevalence and incidence of various pediatric CVDs, emphasizing the impact on global child health. Notably, congenital heart defects, acquired heart diseases, and cardiomyopathies contribute to the majority of pediatric CVDs. Understanding the prevalence and distribution of these conditions is important for resource allocation and healthcare planning. Similarly, several risk factors contribute to the development and progression of pediatric CVD. Genetic predisposition, prenatal exposures, environmental factors, and lifestyle choices all play pivotal roles. Identifying and addressing these risk factors is essential for early intervention and preventive strategies. However, advances in diagnostic modalities have revolutionized the assessment of pediatric CVD. Non-invasive imaging techniques, genetic testing, and biomarker analyses enable earlier and more accurate detection, facilitating timely intervention and personalized treatment plans. Additionally, emerging therapeutic approaches, including innovative medical interventions and surgical techniques, are transforming the landscape of pediatric CVD management.  This abstract aims to serve as a concise resource for clinicians, researchers, and physicians interested in pediatric cardiovascular health. By understanding the epidemiology, recognizing key risk factors, and staying aware of the emerging trends in diagnosis and management, people can contribute to improved outcomes and enhanced quality of life for children affected by cardiovascular diseases.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"50 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139155809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological Profile of Accidental Poisoning in Children, Retrospective Study at Benghazi Children’s Hospital, Libya, 2021","authors":"Eman Alaqeli, Salma. Elzwai, Ahmed Atia, Fawzia Ahmed, Manal Abuagela, Najia Alwaseea, Arij Mousa, Rehab S. Jerbi, A. Ashur, Hamida El Magrahi, Eman Abdulwahed","doi":"10.9734/ajpr/2023/v13i4300","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4300","url":null,"abstract":"Aims: This study aimed to determine the clinical and epidemiological profile, and outcomes of accidental poisonings in children. Study Design:  This observational retrospective study. Place and Duration of Study: General ward and ICU of Benghazi Children's Hospital, from the 1st of January to the 31 of December 2021. Methodology: The study included 232 children up to 15 years old (131 males, 101 females) who were admitted with acute poisoning (either comatose or stable). Complete demographical, clinical, and outcomes data were recorded and analyzed using SPSS version 26.0 software. Results:  out of 232 children admitted for poisoning 56% were drug poisoning, while 44% were non-drug poisoning.  Children, less than 3 years were more liable for poisoning 61.2%. Males were poisoned more than females in all age groups 56.5%. The type of poisoning was found strong correlation with age and was higher in younger (P=.002), living in urban areas (P=.022). The results showed that there was a statistically significant difference between the types of drugs and age groups (P=.000). In almost all cases 93.1% were due to accidental/ unintentional poisoning. More than 88.3% of the cases were exposed to poisoning through the oral route. Overall, 29.3% of drug-poisoning children were asymptomatic, whereas all non-drug-poisoning children were symptomatic and most had mild symptoms. Most cases were discharged in good condition, and only one case died due to anti-psychiatric drug poisoning.  Conclusion: The findings confirm that children under 3 years are more prone to accidental poisoning. Antipsychiatry drugs and cannabis were the most commonly involved in the poisoning. Recommendations: Accidental toxic exposures could be avoidable by preventive measures. The cornerstone of management for children’s poisoning is appropriate public education and raising awareness among parents about safe practices of storing medications and toxic household chemicals.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139212549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Serum IgE Level between Initial Attack and Relapse Cases of Idiopathic Nephrotic Syndrome in Children","authors":"Mohammad Naim Iqbal Mollah, Md. Abdur Rouf, Mohammad Moniruzzaman Bhuiyan, Mohammad Sazzad Hossain Chowdhury, Azreen Chowdhury, Bilkis Sultana","doi":"10.9734/ajpr/2023/v13i4299","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4299","url":null,"abstract":"Background: Nephrotic Syndrome (NS) is a common and recurrent glomerular disease in childhood. Although the exact etiology of NS is not fully known, it is believed that immune system plays a pivotal role in its pathogenesis. Studies have been reported a strong association between NS and increased level of serum immunoglobulin E (IgE). In addition, children with recurrent NS, the IgE level significantly increases, and there is a higher relapse rate. Objective: The aim of the study was to determine the difference of Serum IgE level between initial attack and relapse cases of idiopathic Nephrotic Syndrome in children. Methodology: A cross sectional analytical study has been conducted on 35 initial attack and 35 relapse cases of idiopathic Nephrotic Syndrome children admitted in the Department of paediatrics, Sir Salimullah Medical College Mitford Hospital (SSMCMH), Dhaka from May 2021 to April 2022. Study subjects were enrolled by purposive sampling after confirming the diagnosis and fulfilling the inclusion and exclusion criteria. Informed written consent was taken from each patient's legal guardian before enrollment. A detailed history and thorough physical examination was done in each patient on admission. With all aseptic precaution five ml of venous blood was collected and sent for serum albumin, serum cholesterol and serum IgE level measurement. Data were analyzed using the statistical package for social sciences (SPSS) version 23.0. Independent sample t test or Mann-whitney test was used to compare data between groups. P value of less than 0.05 was considered as significant. Results: The mean age of the studied samples was 3.86 (ranging from 2 to 6 years). Moreover, among the studied sample male was a little bit greater than female. A significant prevalence of relapse cases were found among the children with middle income family status (P<0.05).Spot urine protein and creatinine ratio and serum cholesterol level was significantly higher in patients experience relapse attack (P<0.05). However, serum albumin level was quite similar in both cases. The mean serum IgE of patients experiencing relapse attack was 985.11+433.65 which was significantly higher than patients experiencing initial attack 470.48+227.35 (P<0.001).  Conclusion: This study showed that serum IgE levels are higher in relapse cases of Nephrotic Syndrome than that of initial attack. Furthermore, serum IgE is more in frequent relapse as compared to infrequent relapse. Serum IgE levels have a positive correlation with disease activity and relapse of Nephrotic Syndrome.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139212495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Schizencephaly: A Case Report","authors":"S. A. Ahmed, B. O. Yahia, L. Chtouki, N. Mabrouk, A. Bentahila","doi":"10.9734/ajpr/2023/v13i4298","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4298","url":null,"abstract":"Schizencephaly is a rare anomaly of embryonic development characterized by the presence of linear fissures containing cerebrospinal fluid and lined with dysplastic gray matter, extending from the pial surface of the cerebral hemisphere to the ependymal surface of the lateral ventricle. Schizencephaly can affect one or both cerebral hemispheres, leading to a variety of neurological symptoms such as epilepsy, motor deficits and psychomotor retardation. An antenatal diagnosis can be made; treatment is based on rehabilitation, antiepileptic drugs and supportive psychotherapy. We report the case of a 3-year-old child admitted to our department for a generalized tonicoclonic convulsive seizure resistant to antiepileptic treatment. The child's antecedents included a well-monitored pregnancy carried to term, and a vaginal delivery with no evidence of neonatal distress.  The parents are not consanguineous, but there have been two deaths in the siblings (at 15 days and 40 days) of unknown origin. The child also showed delayed psychomotor development. An MRI scan revealed a type 1 right schizencephaly with a closed cleft, but biology revealed no abnormalities, and genetic studies are still in progress. Management to date is based on antiepileptic drugs, psychomotor rehabilitation and sometimes surgery.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139223235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Chronic Liver Disease (CLD) Based on Esophageal Varices in Children","authors":"Urmi Roy, Aniruddha Mondal, Mohammad Rukunuzzaman","doi":"10.9734/ajpr/2023/v13i4295","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4295","url":null,"abstract":"Background: Chronic Liver Disease (CLD) is a complex and often debilitating condition that affects individuals of all ages, including children. Within pediatric CLD, one critical aspect that demands careful evaluation is the presence and severity of esophageal varices. If left untreated, these enlarged, fragile blood vessels in the esophagus can lead to life-threatening bleeding. The assessment of esophageal varices plays a pivotal role in managing and prognosis of children with CLD. Aim of the Study: The study aims to measure laboratory parameters and calculate serum liver fibrosis scores in CLD children. Methods: This retrospective study analyzed 24 pediatric patients diagnosed with esophageal varices in Chronic Liver Disease (CLD) at the Department of Pediatric Gastroenterology & Nutrition, BSMMU, Dhaka, Bangladesh, over two years from April 2019 to October 2021. Ethical standards were adhered to with informed consent and ethical committee approval. Results: According to the diagnoses, 50% of the patients were identified as having Wilson's disease. Notably, 16.7% of the patients presented with Grade 4 esophageal varices. In terms of laboratory parameters, the median hemoglobin level was 10.2 gm/dl, the total leukocyte count was 6300/mm3, the platelet count had a median of 90000/µL, the bilirubin level had a median of 2.7 gm/dl, ALT had a median of 57 U/L, AST had a median of 134.5 U/L, GGT had a median of 132 U/L, INR had a median of 1.6, albumin had a median of 25 gm/dl, and cholesterol had a median of 105 mg/dl. Lastly, the median liver stiffness was recorded as 13.1 kPa, with an interquartile range (IQR) spanning from 10.3 to 21. Conclusion: This study highlights the importance of early detection and management of esophageal varices in children with CLD, as they are crucial prognostic indicators for underlying liver conditions. By integrating these clinical tools and parameters, healthcare providers can make informed decisions regarding the management and treatment of children with CLD. Early identification of esophageal varices and a comprehensive assessment of the liver's functional status are essential in improving the overall care and outcomes for pediatric patients with chronic liver disease, ensuring timely intervention and support to enhance their quality of life.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"49 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139238171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal and Neonatal Alloimmune Thrombocytopenia: A Concise Review","authors":"S. Ojedokun, T. Oloyede, Ayobami Alabi, Oluwaseyi Oke, Abraham Akinbola, Olawumi Kofoworade, O. Oladibu","doi":"10.9734/ajpr/2023/v13i4296","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4296","url":null,"abstract":"Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare disease resulting from the effect of maternal alloantibodies on fetal human platelet antigens HPAs which could lead to severe haemorrhage. An antibody from mother reacting against a defined platelet alloantigen has been identified as the aetiology of platelet destruction in an infant with this condition and several other platelet-specific antigens were implicated to be capable of initiating maternal immunization during pregnancy leading to fetal platelet destruction. However, in most cases of maternal sensitizations the exposure to fetal blood usually occur during delivery, resulting to thrombocytopenia in the newborn. Current management of fetal and neonatal alloimmune thrombocytopenia in the next pregnancy involves administration of intravenous immune globulin and steroids during antenatal for mothers with previous history or those at risk. Some advances has been suggested in the line of management and these include testing of cell-free fetal DNA obtained from maternal blood to determine the fetal human platelet antigen genotype, the creation of a prophylactic product; a platelet equivalent of Rhesus immune globulin and the development of neonatal Fc receptor inhibitors to replace the current medical therapy administered to pregnant women with an affected fetus. FNAIT is a devastating complication of pregnancy that can present with difficult diagnostic and treatment challenges. Hence, a need for surveillance.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139236474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate and Short-Term Results of Balloon Pulmonary Valvuloplasty from Neonates to Grown Up Children with Critical Pulmonary Stenosis: Experience from a Tertiary Care Centre in Bangladesh","authors":"R. Rima, Abu Sayeed Munshi, Abdul Jabbar, Md. Khalid Ebne Shahid Khan","doi":"10.9734/ajpr/2023/v13i4297","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4297","url":null,"abstract":"Background: Although neonates present with critical pulmonary stenosis (PS) it is equally found in grown up children in developing country like Bangladesh. Balloon pulmonary valvuloplasty (BPV) is one of the most common catheter- based intervention. Transcatheter interventions in critical PS present unique challenges in Bangladesh due to unavailability of expert centre & hardware, cost of procedure, low weight and delayed diagnosis. Careful technique, proper planning & safety measures reduces the incidence of complications. Objective: The study was undertaken to find out the immediate & mid-term outcome of critically ill neonates, infants, children, adolescent who needed emergency pulmonary valvuloplasty for critical PS. Methods: This retrospective study was conducted in the cardiac centre of Bangladesh Shishu Hospital & Institute between June 2014 to June 2022. Percutaneous balloon pulmonary valvuloplasty done in 54 children having critical stenosis or membranous pulmonary atresia.  Clinical parameters, SPO2, echocardiographic data, cathlab data & outcome were recorded. Statistical analysis was done by using SPSS version 24. Results: Among these neonates were 6(11.8%), infants between 1 month to one year was 30(58.8%), from 1 year to 5 years 10(19.6%), more than 5 years 5(9.8%). Median weight was 6.5 kg; lowest weight was 1.96 kg. The peak systolic gradient reduced from an average of 66 ± 7 mm Hg to 16.5 ± 5 mm Hg (P value <0.05). No major complication occurred except mild PR, RV dysfunction, transient bradycardia. Two patients died due to sudden cardiac arrest after six hours of procedure. At 1 month follow up 12 patients had mild residual stenosis, 5 had moderate residual pulmonary stenosis and 2 had severe residual pulmonary stenosis. At 6 month follow up four patients had mild residual pulmonary stenosis & one had moderate pulmonary stenosis. Conclusion: Balloon pulmonary valvuloplasty appears feasible, effective and relatively safe initial management & having encouraging immediate & short term results of critical pulmonary valve stenosis in the neonate to grown up children.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"388 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139237036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Correlation between Cord Blood Lipid Profile and Birth Weight among Term Babies","authors":"P. A. Rathod, A. Jadhao, M. P. Shah, S. S. Pathare, S. G. Vengurlekar, Kalpana Ganesh Kinage","doi":"10.9734/ajpr/2023/v13i4294","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4294","url":null,"abstract":"Aims: This study aimed to examine the association between cord blood lipid levels and neonatal birth weight. Study Design: Hospital based prospective cross-sectional study. Place and Duration of Study: Study was conducted in Government medical College Nagpur, a tertiary care hospital that provides maternal and child health services between June 2011 to March 2013 Methodology: We enrolled 200 healthy pregnant women who attended antenatal clinics in our hospital. We collected 5 mL of cord blood from the umbilical vein and measured the serum levels of total cholesterol, triglycerides, HDL cholesterol, and LDL cholesterol using spectrophotometric methods. We calculated LDL cholesterol using Friedewald’s formula, and we measured anthropometric parameters using standard methods. Results: Neonates  with SGA had significantly lower birth weight (2.24 ± 0.3 vs 2.83 ± 0.4; P < 0.01), head circumference (31.5 ± 1.5 vs 33.4 ± 1.8; P < 0.04), recumbent length (51.2 ± 0.3 vs 53.6 ± 0.2; P < 0.04), and Ponderal Index (2.24 ± 0.5 vs 2.35 ± 0.2; P < 0.03) than AGA babies. The cord blood lipid profile levels were also significantly lower (P < 0.001) in AGA than SGA babies. There was a positive correlation between birth weight and total cholesterol (r = 0.31; P < 0.001) and triglycerides (r = 0.46; P < 0.001), and a small positive correlation between birth weight and HDL cholesterol (r = 0.157; P = 0.013). Conclusion: SGA babies had significantly higher cord blood lipid profile levels than AGA babies. The lipid profile of umbilical cord blood is related to the fetal nutritional status and growth and development. This may have implications for the prevention and management of low birth weight and its associated complications","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"33 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nager Syndrome Co-Harboring Mutation Consistent with Stickler Syndrome: A Rare Case Report","authors":"Asha Prakash Mohapatra, Ankita Satpathy, Athulya P.U., Leena Das, Ipsita Mohapatra","doi":"10.9734/ajpr/2023/v13i4293","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4293","url":null,"abstract":"Nager syndrome, or preaxial acrofacial dysostosis, is a rare malformation characterized by abnormalities of the craniofacial skeleton and limbs. Although most cases are sporadic and some cases have been demonstrated to have an autosomal dominant or recessive mode of inheritance, SF3B4 haploinsufficiency is the most common genetic abnormality identified in this, of which only around 100 cases have been reported so far in the literature. Classically characterized by ante-mongoloid slant, retrognathia, midface retrusion and proximal limb abnormalities like thumb aplasia or hypoplasia, arachnodactyly and radioulnar synostosis, the significant morbidity and mortality in this challenging condition is primarily due to airway abnormalities causing respiratory obstruction. We report a case of genetically confirmed Nager syndrome simultaneously harbouring a mutation consistent with Stickler syndrome type II.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139262081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Congenital Nasal Pyriform Aperture Stenosis","authors":"E. Bahous, S. A. Ahmed, A. Ayad, S. Saghir, M. Sellouti, R. Abilkassim, A. Agadr","doi":"10.9734/ajpr/2023/v13i3278","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i3278","url":null,"abstract":"Introduction: Congenital nasal pyriform aperture stenosis is a rare cause of neonatal respiratory distress. \u0000Observation: A female neonate was born by cesarean section at 39 SA for hydramnios, triple scarred uterus and macrosomia. He was macrosomic and had no facial dysmorphia, he presented at H1 of life with respiratory distress and noisy mouth breathing. He cyanosed with each feeding attempt. On facial CT, the choanae were patent with a median central incisor and piriformis orifice stenosis. Nasal breathing gradually normalized. The hospitalization lasted 8 days with a good evolution. \u0000Discussion: Congenital piriformis stenosis is a rare cause of congenital nasal obstruction. The association with median incisor syndrome is not exceptional. Diagnosis must be made early for proper management. Cyanosis and false airway can be life threatening. Associated abnormalities should be investigated by CT and MRI. Treatment is variable and may be surgical if the stenosis is severe. The prognosis is good in the absence of severe malformations or associated mental retardation. \u0000Conclusion: In case of neonatal respiratory distress, the Congenital pyriformis stenosis must be among the causes, a rapid diagnostic assessment and management are necessary.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116114835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}