Asian Journal of Pediatric Research最新文献

{"title":"Is Prone Positioning Worth the Turn in Pediatrics? Unraveling the Oxygenation Mystery in Ventilated Patients with Acute Respiratory Distress Syndrome: An Observational Study Introducing a Novel SF Ratio Method for Non-Invasive Monitoring in Children","authors":"Adil Nizar, Asok Kumar Mandaland, Gobinda Mondal","doi":"10.9734/ajpr/2024/v14i2324","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i2324","url":null,"abstract":"Background: Respiratory illnesses are prevalent among children, attributed to factors such as immature immune systems, anatomical variations, and increased susceptibility to infections. Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality, necessitating various forms of respiratory support in pediatric intensive care units (PICUs). Prone positioning has emerged as a strategy to improve oxygenation in ARDS, but its effectiveness and correlation with non-invasive monitoring parameters remain underexplored. \u0000Subjects and Methods: This prospective observational study, conducted in the PICU of Dr. B.C Roy PGIPS, Kolkata, aimed to assess the impact of prone ventilation on oxygenation in children diagnosed with ARDS. The study, spanning 18 months, included 40 patients aged 3 months to 12 years requiring mechanical ventilation. Parameters such as oxygenation index (OI), oxygen saturation index (OSI), PF ratio, and SF ratio were monitored at different time points during supine and prone ventilation. Prone positioning's effectiveness was evaluated based on improvements in these parameters. \u0000Results: The study revealed a significant improvement in oxygenation status after four hours of prone ventilation compared to supine ventilation. Oxygenation index, OSI, SF ratio, and PF ratio showed statistically significant changes favoring prone positioning. A strong positive correlation between SF ratio and PF ratio was observed at various time points, emphasizing the potential of SF ratio as a non-invasive alternative. Responders and non-responders to prone positioning were identified based on predefined criteria, highlighting individual variability in treatment response. \u0000Conclusion: Prone ventilation demonstrated significant improvements in oxygenation parameters in children with ARDS. The study supports the use of non-invasive SF ratio as a reliable substitute for PF ratio, simplifying monitoring without invasive arterial sampling. This finding has implications for improving ARDS management strategies in pediatric patients, offering a less cumbersome alternative for assessing oxygenation status.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMDDHH: A Contribution to the Understanding of the Disease","authors":"Asha Prakash Mohapatra, Pusparaj Aditinandan Pradhan, Gayatri Ray, Rakesh Satapathy, D. Manasa","doi":"10.9734/ajpr/2024/v14i2323","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i2323","url":null,"abstract":"Inborn Errors of Immunity (IEI) is an extremely rare group of heterogenous disorders which are characterized by predisposition to severe unusual and recurrent infections, severe allergies, features suggestive of autoimmune conditions and sometimes malignancies. We report a two-year-old female child presented to our emergency department with complaints of a history of recurrent respiratory infections, recurrent skin infections and a recent history of purulent discharge from both ears. Clinical examination revealed acute otitis media, pneumonia, multiple healed skin lesions associated with soft non-tender hepatomegaly and normal cardiac findings. Elevated hepatic transaminases and hypogammaglobulinemia suggested the possibility of an inborn error of immunity. A whole exome sequencing study performed on the patient established a diagnosis of IMDDHH (Immunodeficiency, Developmental Delay, and Hypohomosyteinemia) by revealing a missense mutation in the NFE2L2 gene of chromosome 2q31. Diagnosing such conditions with inborn errors of immunity requires a high index of suspicion combined with a comprehensive knowledge of the structure and function of both innate and adaptive immune systems. Recurrent skin and respiratory infections in a growing child belonging to a low-and-middle-income country like India is a common clinical scenario encountered frequently in pediatric clinic practice and is often ignored after attributing it to poor hygienic conditions. However, with careful history taking and examination, a sub-group of such patients may be isolated with a high probability of an underlying IEI, which can later be confirmed by genetic work-up.  ","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139799780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMDDHH: A Contribution to the Understanding of the Disease","authors":"Asha Prakash Mohapatra, Pusparaj Aditinandan Pradhan, Gayatri Ray, Rakesh Satapathy, D. Manasa","doi":"10.9734/ajpr/2024/v14i2323","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i2323","url":null,"abstract":"Inborn Errors of Immunity (IEI) is an extremely rare group of heterogenous disorders which are characterized by predisposition to severe unusual and recurrent infections, severe allergies, features suggestive of autoimmune conditions and sometimes malignancies. We report a two-year-old female child presented to our emergency department with complaints of a history of recurrent respiratory infections, recurrent skin infections and a recent history of purulent discharge from both ears. Clinical examination revealed acute otitis media, pneumonia, multiple healed skin lesions associated with soft non-tender hepatomegaly and normal cardiac findings. Elevated hepatic transaminases and hypogammaglobulinemia suggested the possibility of an inborn error of immunity. A whole exome sequencing study performed on the patient established a diagnosis of IMDDHH (Immunodeficiency, Developmental Delay, and Hypohomosyteinemia) by revealing a missense mutation in the NFE2L2 gene of chromosome 2q31. Diagnosing such conditions with inborn errors of immunity requires a high index of suspicion combined with a comprehensive knowledge of the structure and function of both innate and adaptive immune systems. Recurrent skin and respiratory infections in a growing child belonging to a low-and-middle-income country like India is a common clinical scenario encountered frequently in pediatric clinic practice and is often ignored after attributing it to poor hygienic conditions. However, with careful history taking and examination, a sub-group of such patients may be isolated with a high probability of an underlying IEI, which can later be confirmed by genetic work-up.  ","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139859707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Hygiene Index in Children with Stainless Steel Crowns in the Permanent Molars","authors":"V. Karthik, E. M. G. Subramanian","doi":"10.9734/ajpr/2024/v14i2322","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i2322","url":null,"abstract":"Aim: The aim of this study is to assess the oral hygiene index in children with stainless steel crowns in the permanent molars. \u0000Introduction: Dental caries is a common disease, especially in children. Stainless steel crowns are used for the rehabilitation of carious molars to restore form and function either after root canal treatment or when caries is multi surface. Plaque and debris accumulates around these crowns if children fail to maintain it properly. Oral Hygiene Index shows patient’s oral hygiene and the presence of plaque on the surface of the teeth. \u0000Materials and Method: This was a retrospective study conducted in a private dental institution in Chennai. The data was collected from the digital archives information system. 100 patients who fulfilled the inclusion and exclusion criteria were included in the study. The data analysis was performed using SPSS software .The chi square test and pearson correlation was done. p value <0.05 was considered statistically significant. \u0000Result: 24 patients had the OHIS score of 1.5, 18 patients had the OHIS score of 2, 24 patients had the OHIS score of 2.5,18 patients had the OHIS score of 3, 16 patients had the OHIS score of 1. Boys had higher OHI scores compared to girls. \u0000Conclusion: Within the limitations of the study, it can be concluded that 40% children had good oral hygiene scores. Girls had better oral hygiene scores compared to boys. Oral hygiene instructions should be given to children with stainless steel crowns to prevent the spread of caries and gingival diseases to adjacent teeth.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"118 1-4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Presentation and Etiologic Diagnosis of Disorders of Sex Development in Children in Senegal","authors":"Babacar Niang, Fatou Ly, Y. Kéita, A. Mbaye, Djibril Boiro, A. Sow, Abou Ba, I. Dème-Ly, Aliou Thiongane, A. Ndongo, Papa Moctar Faye, Amadou Lamine Fall, Ousmane Ndiaye","doi":"10.9734/ajpr/2024/v14i1317","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i1317","url":null,"abstract":"Introduction: Disorders of Sex Development (DSD) refer to situations where chromosomal, gonadal or anatomical sex is atypical. We aimed to describe the baseline characteristics on clinical and etiological diagnosis of DSD in Senegalese children.\u0000Methods: This retrospective cohort study over a period of 8 years (2015-2022) included all children aged 0 to 18 years followed for DSD at the pediatric endocrinology department of NCHAR in Dakar. Sociodemographic clinical, paraclinical (genetics, imaging, hormonal) parameters were collected and analyzed with Epi Info 7.2. The description was made using position and dispersion parameters and illustrations in the form of appropriate tables and graphs. Bivariate analysis was used for associations between variables, with an alpha error risk of 5% and a CI of 95%. All ethical rules have been respected.\u0000Results: We included 102 DSD cases. Only 61 patients (59.80%) had a genetic diagnosis. Mean age at diagnosis was 31.2 ± 46.6 months. Rearing sex of child was male in 35 cases (57.38%) and female in 22 cases (36.06%) and undetermined in 4 cases (6.56%). Based on karyotype analysis, 31(50.82%) of children had 46,XY DSD, 27 (44.26%) had 46,XX DSD and three (4.92%) children with sex chromosome DSD. Etiologies were dominated by congenital adrenal hyperplasia (81.48%) and androgen insensitivity (38.71%) in 46,XX  and 46,XY DSD respectively. External masculinization score > 4, palpation of a gonad, a phallus length > 2.5, a single urogenital orifice as well as ultrasound sex were associated with the XY karyotype.\u0000Conclusion: Health care professional and medical students should be trained for early diagnosis. A national guideline should be developed for diagnosis and management of DSD during and beyond the pediatric age group, and adapted to evidence and available resources. This can only be achieved if the management of DSD is supported by universal health insurance.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"9 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139443670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wandering Spleen in Operated Case of Congenital Diaphragmatic Hernia","authors":"B. V. Musande, Arjun Pawar, Rajendra Shinde, Nikita N. Marathe, Yash Marathe","doi":"10.9734/ajpr/2024/v14i1315","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i1315","url":null,"abstract":"Wandering spleen (WS) is a rare condition characterized by abnormal mobility of the spleen due to laxity or absence of its supporting ligaments. We report an exceptional case of WS in a pediatric patient who had previously undergone surgical repair for congenital diaphragmatic hernia (CDH). A 16-year-old male, with a history of CDH repair in infancy, presented with a two-day history of abdominal pain and vomiting. Clinical examination revealed abdominal distension, tenderness, and sluggish bowel sounds. Imaging studies, including a contrast-enhanced computed tomography (CECT) scan, indicated small bowel obstruction due to an internal hernia, potentially involving the foramen of Winslow. Intriguingly, the patient's spleen had migrated to the left iliac fossa, accompanied by partial thrombosis of the splenic vein. Surgical intervention was deemed necessary. During exploratory laparotomy, the patient was found to have a reversed anatomy, with the ascending colon, cecum, and appendix on the left side, and the small bowel on the right side. Additionally, a WS was discovered with a long and tortuous splenic vein and artery. Surgical procedures included adhesiolysis, primary closure of serosal tears, splenopexy for spleen repositioning, and bowel derotation. The patient's postoperative recovery was uneventful, and he was monitored closely to ensure the resolution of the complications associated with this unique presentation.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"63 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139448901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relative Adrenal Insufficiency in Full-Term and Preterm Neonates with Neonatal Sepsis","authors":"Reem Mohamed Elsheikh, Abdelrahman Mohamed Elmashad, Amany Mohamed Aboelenin, S. M. Elrifaey","doi":"10.9734/ajpr/2024/v14i1314","DOIUrl":"https://doi.org/10.9734/ajpr/2024/v14i1314","url":null,"abstract":"Background: Neonatal sepsis is the third most common cause of death in newborns and a significant issue for public health, particularly in developing nations. This study aimed to assess the hypothalamic-pituitary-adrenal axis (HPA) response in full-term and preterm newborns diagnosed with neonatal sepsis in the neonatal intensive care unit (NICU). \u0000Methods: This cross-section observational research was done on neonates who were categorized into two main groups Group I: Sepsis neonates who were further subdivided into two groups according to the gestational age into 30 full-term neonates with neonatal sepsis and 30 preterm neonates with neonatal sepsis. Group II: Included 30 healthy control neonates. \u0000Results: HSS score and C reactive protein (CRP) level were correlated with serum cortisol level at (9 am: r=-0.273, P<0.035 and r=-0.447, P<0.001), (9 pm: r=-0.447, P<0.001and r=-0.477, P<0.001) ACTH at (9 am: r=-0.314, P<0.015 and r=-0.377, P<0.003) and at (9 pm: r= -0.362, P<0.005 and r=-0.448, P<0.001)  and cortisol level post ACTH stimulation (r=-0.345, 0.007 and r=-0.497, P<0.001) respectively. Regarding inotropes, sepsis type and oxygen support there was significant difference between both groups. \u0000Conclusions: 75% of the patients we evaluated with neonatal sepsis had relative adrenal insufficiency (RAI). ACTH and Cortisol values were correlated to CRP and HSS score as an inflammatory marker. This reflects suppressed HPA status in this critical clinical condition.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"102 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139388041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achenbach Syndrome in a Male Infant with Brown Discoloration of Skin: A Case Report","authors":"Soham Samajpaty","doi":"10.9734/ajpr/2023/v13i4312","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4312","url":null,"abstract":"Achenbach syndrome or paroxysmal hand hematoma is a rare and scantily found medical condition. It is a condition with benign, spontaneous, self-limiting focal hemorrhage under the skin, mostly located in the extremities of upper limb or lower limb, mostly displaying bluish discoloration of skin. Here, a brief communication in the form of case report of 1 year old child from Russian Federation is being presented, which was compatibly diagnosed to be Achenbach syndrome by analyzing the history and other medical reports. The typical nature of the case being presented is that the patient had brown discoloration of skin rather than blue and experienced no pain as reported by guardians of the patient.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"354 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adams-Oliver Syndrome (OSA)","authors":"A. Ourrai, Sanae. Azitoune, A. Hassani, Aomar. Agadr, R. Abilkassem","doi":"10.9734/ajpr/2023/v13i4313","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4313","url":null,"abstract":"Introduction: Adams-Oliver's syndrome (SAO) is a rare genetic condition characterized by the association of lumb anomalies and Aplasia cutis congenita in vertex, often accompanied by underlying ossification defect and vascular lesions. The objective through this new observation is to describe the clinical, radiological, therapeutic and evolutionary elements according to what was described up to there in the literature. Observation: Female newborn child, stemming from a pregnancy followed with normal obstetric ultrasounds. He presents a scalp agenesis, underlying cranial bone aplasia and toes hypoplasia with syndactyly. The association of these two major criteria allowed making the diagnosis of SAO. Moreover, she presents disjointed and large sagittal suture with left parietal bone borders hypoplasia. The notion of periventricular bleeding. The rest of the balance sheet deformation, namely the abdominal ultrasound and echocardiography was without anomalies. The newborn was sent in neurosurgery for restorative treatment, which will be planned at the age of 3 months. Discussion and Conclusion: This observation illustrates sporadic and not complicated SAO. The absence of complete gene mapping in SAO and therefore of any genetic counseling, prenatal morphological ultrasound, is making important in evolutionary terms of subsequent pregnancies.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"41 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Prognostic Factors for Abnormal Neurodevelopmental Outcomes in Children with Acute Bacterial Meningitis by Using RNDA Tool","authors":"S. M. S. Islam, Wahida Khanam","doi":"10.9734/ajpr/2023/v13i4311","DOIUrl":"https://doi.org/10.9734/ajpr/2023/v13i4311","url":null,"abstract":"This observational follow up study was carried in the Department of Paediatrics, Institute of Child and Mother Health (ICMH), Matuail, Dhaka, during November 2016 to December 2017, to determine the prognostic factors for assessment of the prognostic factors for abnormal neurodevelopmental outcomes in children with acute bacterial meningitis by using RNDA tool. A total of 56 children with acute bacterial meningitis of age > 1month - 15 years admitted in the inpatient department were enrolled in this study. Most 34 (60.7%) of the children belonged to age <12 months and male to female ratio was almost 2:1. More than half (58.9%) children admitted >48hrs after onset of illness, 11(19.6%) children received previous treatment with antibiotics and most (85.7%) of the children had occurrence of seizures prior to admission. More than one third (39.3%) children had >100 cell count in their CSF. CSF glucose/ serum glucose ratio was found <0.2 in case of 8(14.3%) children. More than three fourth (78.6%) children had high protein in their CSF. Abnormal developmental outcome assessed by RNDA on follow ups. It was observed that gross motor development was mildly impaired in 6(12.0%), 8(16.3%) and 5 (11.6%) cases on 1st, 2nd and 3rd follow up respectively. Gross motor was moderately impaired in 4 (8.0%), 3 (6.1%) and 3 (7.0%) cases on 1st, 2nd and 3rd follow up respectively. Accordingly, fine motor was mild impaired in 5 (10.0%), 4 (8.2%) and 5 (11.6%) cases and moderately impaired in 2 (4.0%), 3 (6.1%) and 2 (4.7%) cases on 1st, 2nd and 3rd follow up respectively. Cognition was mild impaired in 11 (22.0%), 12 (24.5%) and 11 (25.6%) cases and moderately impaired in 4 (8.0%), 4 (8.2%) and 3 (7.0%) cases on 1st, 2nd and 3rd follow up respectively. Children found with any selective neurological complication or abnormal developmental outcome in at least one follow up was considered to be abnormal. Hypertonic muscle tone and exaggerated jerk was found in 2(3.8%) children. 5(9.6%) children had developmental regression on follow up. 3(5.8%) children had squint, 2 (3.8%) children had subdural effusion, 2 (3.8%) children had visual deficit, 6 (11.5%) children had hearing deficit and 4 (7.7%) children had afebrile seizures on follow up. One (11.1%) child with focal seizure and 6 (60.0%) children with hazy CSF colour had significantly (p<0.05) developed abnormal developmental outcome. Children under 12 months of age, children who received previous treatment with antibiotics, seizures prior to admission, high WBC count, hazy CSF colour and CSF glucose/ serum glucose ratio below 0.2 were significantly (p<0.05) associated with acute complications during hospital stay. Children with focal seizure and children with hazy CSF colour were significantly (p<0.05) associated to abnormal developmental outcome. Multivariate regression analysis showed no significant (p>0.05) association between acute complications and prognostic factors. Age under 12 months in adjusted OR 0.970 with 95.","PeriodicalId":393364,"journal":{"name":"Asian Journal of Pediatric Research","volume":"348 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}