Epidemiological Profile of Accidental Poisoning in Children, Retrospective Study at Benghazi Children’s Hospital, Libya, 2021

Eman Alaqeli, Salma. Elzwai, Ahmed Atia, Fawzia Ahmed, Manal Abuagela, Najia Alwaseea, Arij Mousa, Rehab S. Jerbi, A. Ashur, Hamida El Magrahi, Eman Abdulwahed
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Abstract

Aims: This study aimed to determine the clinical and epidemiological profile, and outcomes of accidental poisonings in children. Study Design:  This observational retrospective study. Place and Duration of Study: General ward and ICU of Benghazi Children's Hospital, from the 1st of January to the 31 of December 2021. Methodology: The study included 232 children up to 15 years old (131 males, 101 females) who were admitted with acute poisoning (either comatose or stable). Complete demographical, clinical, and outcomes data were recorded and analyzed using SPSS version 26.0 software. Results:  out of 232 children admitted for poisoning 56% were drug poisoning, while 44% were non-drug poisoning.  Children, less than 3 years were more liable for poisoning 61.2%. Males were poisoned more than females in all age groups 56.5%. The type of poisoning was found strong correlation with age and was higher in younger (P=.002), living in urban areas (P=.022). The results showed that there was a statistically significant difference between the types of drugs and age groups (P=.000). In almost all cases 93.1% were due to accidental/ unintentional poisoning. More than 88.3% of the cases were exposed to poisoning through the oral route. Overall, 29.3% of drug-poisoning children were asymptomatic, whereas all non-drug-poisoning children were symptomatic and most had mild symptoms. Most cases were discharged in good condition, and only one case died due to anti-psychiatric drug poisoning.  Conclusion: The findings confirm that children under 3 years are more prone to accidental poisoning. Antipsychiatry drugs and cannabis were the most commonly involved in the poisoning. Recommendations: Accidental toxic exposures could be avoidable by preventive measures. The cornerstone of management for children’s poisoning is appropriate public education and raising awareness among parents about safe practices of storing medications and toxic household chemicals.
儿童意外中毒的流行病学概况,利比亚班加西儿童医院的回顾性研究,2021 年
研究目的:本研究旨在确定儿童意外中毒的临床和流行病学特征及结果。 研究设计: 观察性回顾研究。 研究地点和时间:班加西儿童医院普通病房和重症监护室,时间为 2021 年 1 月 1 日至 12 月 31 日。 研究方法:研究对象包括 232 名因急性中毒(昏迷或病情稳定)入院的 15 岁以下儿童(男 131 名,女 101 名)。使用 SPSS 26.0 版软件记录和分析了完整的人口统计学、临床和结果数据。 结果:在收治的 232 名中毒儿童中,56% 为药物中毒,44% 为非药物中毒。 3岁以下儿童更容易中毒,占61.2%。在所有年龄组中,男性中毒人数多于女性,占 56.5%。中毒类型与年龄密切相关,年龄越小(P=0.002)、居住在城市地区(P=0.022)的中毒率越高。结果表明,药物种类和年龄组之间存在显著的统计学差异(P=.000)。几乎所有病例中都有 93.1%是由于意外/无意中毒造成的。超过 88.3% 的病例是通过口服途径中毒的。总体而言,29.3%的药物中毒儿童无症状,而所有非药物中毒儿童均有症状,且大多数症状轻微。大多数病例出院时情况良好,只有一例因抗精神药物中毒而死亡。 结论研究结果证实,3 岁以下儿童更容易发生意外中毒。抗精神病药物和大麻是最常见的中毒原因。 建议:采取预防措施可以避免意外中毒。处理儿童中毒问题的基石是开展适当的公众教育,提高家长对储存药物和有毒家用化学品的安全意识。
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