{"title":"[Evaluation of Patient Satisfaction in Robot-Assisted Radical Prostatectomy].","authors":"Kai Yazaki, Satoshi Washino, Takanori Hayase, Kimitoshi Saito, Yuki Nakamura, Kosuke Kazashi, Kohei Mito, Naoki Fujisawa, Tomoaki Miyagawa","doi":"10.14989/ActaUrolJap_71_11_375","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_11_375","url":null,"abstract":"<p><p>This study investigated the factors that contribute to surgical satisfaction in robot-assisted radical prostatectomy (RARP). We assessed a total of 208 patients who underwent RARP for prostate cancer between May 2020 and April 2022 and completed the Expanded Prostate Cancer Index Composite (EPIC) questionnaire. The EPIC questionnaire was evaluated in the first and second year after surgery. We examined how treatment outcomes, such as urinary continence, sexual function, resection margins, and PSA recurrence, were associated with patient satisfaction. In the first year, 22, 52, 21, 3, and 2% of the patients were very satisfied (5 points), satisfied (4 points), neither satisfied nor dissatisfied (3 points), dissatisfied (2 points), and very dissatisfied (1 point), respectively ; the corresponding patient satisfaction in the second year was 24, 46, 27, 1, and 2%. Urinary continence was a significant factor contributing to patient satisfaction in the first and second postoperative years. Other outcomes were not statistically associated with patient satisfaction in the first or second year. In conclusion, postoperative urinary continence was the most significant factor contributing to patient satisfaction.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 11","pages":"375-379"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A Case of Two Percutaneous Nephrolithotomies for Recurrent Transplant Kidney Stones Following Ureteral Stenosis Surgery Performed after Kidney Transplantation].","authors":"Toshiro Muraki, Mayumi Ando, Daijoro Nishijima, Sho Akimoto, Kazuki Matsushita, Daisuke Ishii, Kazumasa Matsumoto, Sho Watanuki, Norio Maru","doi":"10.14989/ActaUrolJap_71_11_393","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_11_393","url":null,"abstract":"<p><p>The patient was a 56-year-old woman who had previously undergone living-donor kidney transplantation, followed by urinary diversion surgery due to recurrent pyelonephritis. Nine years after the urinary diversion, abdominal computed tomography performed for evaluation of lower abdominal pain revealed a renal calculus in the transplanted kidney. Percutaneous nephrolithotomy resulted in satisfactory stone fragmentation, but had to be performed again 14 months later to remove a residual stone that had increased in size.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 11","pages":"393-397"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Efficacy and Safety of Rezum® Water Vapor Therapy for Treating Urinary Retention: Analysis of 34 Cases in Japan].","authors":"Kazunori Haga, Keigo Akagashi, Musashi Tobe, Kosuke Uchida, Ichiya Honma, Megumi Hirobe, Junji Ishizaki, Takashi Shimizu, Keitaro Watanabe, Kazuki Takekawa, Hisao Nakajima, Satoshi Urahama, Yoshikazu Sato","doi":"10.14989/ActaUrolJap_71_11_381","DOIUrl":"10.14989/ActaUrolJap_71_11_381","url":null,"abstract":"<p><p>Rezum® water vapor therapy is a minimally invasive treatment for benign prostatic hyperplasia (BPH) that utilizes sterile water vapor injections into the prostate to achieve tissue ablation. This study evaluates the real-world efficacy and safety of Rezum® in managing catheter-dependent urinary retention in a multimorbid patient population. A prospective, single-center study was conducted involving 34 consecutive patients with catheter-dependent urinary retention treated with Rezum® between 2022 and 2024. Patient demographics and procedural characteristics were documented. Post-treatment outcomes, including adverse events, International Prostate Symptom Score (IPSS), quality of life (QO), overactive bladder symptom score (OABSS), post-void residual volume (PVR), and prostate volume, were analyzed. Among the 34 patients, with a mean age of 80.6 years, 33 (97%) achieved spontaneous, catheter-free voiding following the procedure. Symptomatic improvements were noted, with post-treatment mean scores of IPSS at 5.9, QOL at 1.5, and OABSS at 4.1. PVR decreased significantly from 801 ml to 45.2 ml (94% reduction), and prostate volume was reduced from 54.6 ml to 34.7 ml (36% reduction), both with statistical significance (p<0.01). Adverse events were mild and infrequent, including gross hematuria in 9% and febrile urinary tract infections in 3%. Rezum® represents an effective and safe minimally invasive therapeutic option for catheter-dependent patients. This novel technique is particularly advantageous for individuals at heightened risk of bleeding or those deemed high-risk for anesthesia.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 11","pages":"381-386"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A Case of Statin-Associated Muscle Symptoms (SAMS) Due to Drug-Drug Interaction between Statin and Pazopanib].","authors":"Yudai Funakoshi, Atushi Koizumi, Junichi Nadaoka, Masatoshi Kanzaki, Teruaki Kumazawa","doi":"10.14989/ActaUrolJap_71_10_333","DOIUrl":"10.14989/ActaUrolJap_71_10_333","url":null,"abstract":"<p><p>A woman in her 60s underwent a left nephrectomy in 2007 after being diagnosed with left renal cell carcinoma. In 2020, computed tomography (CT) revealed pancreatic metastasis, and subsequently axitinib therapy was initiated. However, axitinib therapy was discontinued due to hand-foot syndrome and nivolumab therapy was initiated in 2021. Follow-up CT scans indicated the progression of pancreatic and lymph node metastases, prompting the initiation of pazopanib therapy. Twelve days after the initiation of pazopanib therapy, she was admitted to our department with complaints of fever, fatigue, and skin rash. She was hospitalized with suspected drug eruption, drug-induced liver injury, and infection. Her symptoms improved with discontinuation of pazopanib, and antibiotic treatment; however, on the 8ᵗʰ day of hospitalization, she experienced lower limb weakness. On the 16ᵗʰ day, blood tests revealed markedly elevated creatine kinase (CK) levels (26, 565 IU/l). Short tau inversion recovery (STIR) magnetic resonance imaging (MRI) revealed high signal intensity in the hamstring and adductor muscles, leading to the diagnosis of myositis. Consequently, pitavastatin treatment was discontinued. CK levels decreased promptly after the discontinuation of statin treatment, and limb weakness improved as well. Pitavastatin is transported from the blood into the liver via organic anion-transporting polypeptide 1B1 (OATP1B1) located on the hepatocyte surface. Previous reports have indicated that tyrosine kinase inhibitors, such as pazopanib, can inactivate OATP1B1, leading to an increase in the plasma concentration of statins. In the present case, myositis was considered to have resulted from a drug-drug interaction between pitavastatin and pazopanib.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"333-336"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A Case of Staghorn Calculi Treated by Pyelolithotomy Through a Mini-Pararectal Incision].","authors":"Takehiro Nakamura, Ryoji Takazawa, Koki Mitani","doi":"10.14989/ActaUrolJap_71_10_351","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_10_351","url":null,"abstract":"<p><p>We report a case in which pyelolithotomy through a mini-pararectal incision was performed in a patient with right staghorn calculi for whom it was difficult to perform PNL/ECIRS. A 76-year-old woman with right staghorn calculi (60×30×30 mm; total stone volume, 51.29 ml) was admitted to our hospital. The patient had undergone left pelvic bone resection and left external iliac arteriovenous graft replacement for left pelvic osteosarcoma 25 years prior and subsequently required anticoagulant therapy. Anticoagulants were suspended, and heparin and the antibiotics were administered intravenously for three days before surgery. Right pyelolithotomy was performed through an 8 cm pararectal incision in the supine position. A T-shaped incision (5×3 cm) was made in the anterior wall of the renal pelvis and the entire stone was extracted. The operative time was 203 min. Blood loss was 95 g. The postoperative course was uneventful, and the patient was discharged on the 8th postoperative day. The patient successfully achieved stone-free status. This surgical procedure is a viable option in cases in which endourologic lithotripsy is difficult to perform.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"351-354"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wakako Yorozuya, Ko Kobayashi, Ryuichi Kato, Azusa Yamana, Ko Okabe, Yuki Kyoda, Kohei Hashimoto, Toshiaki Tanaka, Naoya Masumori
{"title":"[A Case of Persistent Genital Arousal Disorder/Genito-Pelvic Dysesthesia (PGAD/GPD) Improved with Selective Serotonin Reuptake Inhibitor (SSRI) Treatment].","authors":"Wakako Yorozuya, Ko Kobayashi, Ryuichi Kato, Azusa Yamana, Ko Okabe, Yuki Kyoda, Kohei Hashimoto, Toshiaki Tanaka, Naoya Masumori","doi":"10.14989/ActaUrolJap_71_10_361","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_10_361","url":null,"abstract":"<p><p>Persistent genital arousal disorder/genito-pelvic dysesthesia (PGAD/GPD) causes intense abnormal genital sensations without sexual stimulation. A 74-year-old woman visited our clinic with a tingling sensation in the clitoris. Six months earlier, she had felt lower abdominal discomfort, bladder pain, and abnormal genital sensations and visited the urologist at another hospital. She also had appetite loss, weight loss, and insomnia. A gynecologist diagnosed her symptoms as clitoral-related, but topical treatment was ineffective due to the pain caused by contact. During our examination, there was severe burning pain on clitoral palpation, and we suspected PGAD/GPD. Two weeks after administration of Sertraline, a selective serotonin reuptake inhibitor, her symptoms improved. However, since the effect weakened two weeks after starting treatment, the dosage was increased and her symptoms showed remission thereafter. Her symptoms improved after increasing the dosage. Tarlov cysts in the sacrum revealed by magnetic resonance imaging were considered as the potential cause of PGAD/GPD. Since her symptoms had improved and considering her age and surgical risk, the orthopedic surgeon we consulted recommended follow-up instead of surgery.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"361-363"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Three Cases of Amrubicin Administration as Second-or Third-Line Chemotherapy for Primary Small Cell Carcinoma of the Prostate].","authors":"Takehiro Takahashi, Rina Ogawa, Eriko Tanaka, Masanori Ito, Heisuke Iijima, Tomoya Yokoi, Masakatsu Ueda, Yusuke Shiraishi, Koji Yoshimura","doi":"10.14989/ActaUrolJap_71_10_337","DOIUrl":"10.14989/ActaUrolJap_71_10_337","url":null,"abstract":"<p><p>Small cell carcinoma (SCC) of the prostate has a poor prognosis. We present three cases of primary SCC of the prostate treated with amrubicin as second- or third-line chemotherapy. Case 1 : A 54-year-old male received cisplatin and irinotecan but showed metastatic progression. Amrubicin was initiated as second-line therapy, leading to tumor shrinkage. However, disease progression (PD) occurred in the ninth month, and he passed away 16 months after treatment initiation. Case 2 : An 82-year-old male treated with combined androgen blockade (CAB) later developed pelvic lymph node enlargement, and SCC was diagnosed. He received carboplatin-etoposide and then carboplatin-irinotecan. Amrubicin was given as third-line therapy but showed no significant response. He passed away 24 months after treatment initiation. Case 3 : A 68-year-old male treated with CAB developed M0CRPC and later distant lymph node metastases, confirmed as SCC. He received cisplatin-etoposide and then amrubicin as second-line therapy, achieving a partial response initially but experiencing PD in the fifth month. He passed away 36 months after starting treatment. Amrubicin may be a therapeutic option for primary SCC of the prostate, but achieving prolonged survival remains difficult.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"337-344"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Two Cases of Bulbous Urethral Complete Disruption Treated by Immediate Urethral Anastomosis].","authors":"Mahoro Watanabe, Eiichiro Ohara, Takuya Inoue, Shigeto Ishidoya","doi":"10.14989/ActaUrolJap_71_10_355","DOIUrl":"10.14989/ActaUrolJap_71_10_355","url":null,"abstract":"<p><p>We report two cases of bulbous urethral complete disruption treated by immediate anastomosis. Both patients were injured in traffic accidents and diagnosed with internal pudendal artery injury, perineal hematoma, and bulbous urethral complete disruption. We performed surgical hematoma drainage, perineal hemostasis, and end-to-end urethral anastomosis, which led to good voiding function after surgery. Immediate urethral repair might be an effective choice for selected cases of bulbous urethral disruption because of the short interval to spontaneous voiding and cystostomy catheter removal.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"355-359"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Factors of Treatment Efficacy in Salvage Radiotherapy without Concomitant Hormonal Therapy for Biochemical Recurrence after Radical Prostatectomy].","authors":"Sota Inaba, Takeshi Sasaki, Minori Nakatani, Chinatsu Sawai, Shunsuke Owa, Taketomo Nishikawa, Momoko Kato, Shinichiro Higashi, Yusuke Sugino, Satoru Masui, Kouhei Nishikawa, Shiori Tanaka, Goshi Kitano, Manabu Kato, Takahiro Kojima, Takuji Shibahara, Takehisa Onishi, Takahiro Inoue","doi":"10.14989/ActaUrolJap_71_10_327","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_10_327","url":null,"abstract":"<p><p>This study investigated the factors associated with the success of salvage radiotherapy (SRT) defined as PSA reaching less than 0.2 ng/ml without concomitant hormonal therapy after biochemical recurrence (BCR) following radical prostatectomy (RP). The study included 38 patients who underwent robot-assisted radical prostatectomy (RARP) and received SRT alone from 2015 to 2021. Patients with prior treatments, those who underwent hormonal therapy, patients whose PSA did not decrease to less than 0.2 ng/ml after RARP, and pN1 cases were excluded. The median age and PSA at the start of SRT were 68 years and 0.26 ng/ml, respectively, and positive surgical margins were observed in 14 cases (37%). The median follow-up time from the start of SRT was 36.1 months, and 52.6% of the cases achieved SRT success with SRT alone. Multivariate analysis demonstrated that pre-SRT PSA <0.25 ng/ml and positive surgical margins were significantly different between SRT success cases and non-SRT success cases.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"327-332"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akitaka Aoki, Toshiyasu Amano, Yuki Matsumoto, Tetsuya Imao
{"title":"[Acute Stone Street Formation Due to Spontaneous Emptying of Calyceal Diverticulum].","authors":"Akitaka Aoki, Toshiyasu Amano, Yuki Matsumoto, Tetsuya Imao","doi":"10.14989/ActaUrolJap_71_10_345","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_10_345","url":null,"abstract":"<p><p>A 73-year-old woman presented with a chief complaint of left-sided abdominal pain from the time of waking. She had a calcified lesion in the left kidney for at least 4 years, but as she was asymptomatic, a detailed examination was not performed. Owing to the sudden onset of left-sided abdominal pain, she visited her local emergency department, where left renal and ureteral stones were identified on computed tomography. She was then referred to our department. A diagnosis of calyceal diverticulum stone disease and associated stone street was made on the basis of retrograde urography and other tests. Transurethral lithotripsy was performed under general anesthesia. A soft ureteroscope was successfully inserted into the diverticulum, where numerous stones were found. After three sessions of transurethral lithotripsy, all stones were removed. The main stone component was calcium oxalate. In this case, it was considered that the 4-year-duration nephrocalcific lesion (calyceal diverticular stones) had drained rapidly from the diverticulum to form a stone street.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 10","pages":"345-349"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}