Acta Urologica Japonica最新文献_第10页

[Risk Factors of Antiresorptive Agent-Related Osteonecrosis of the Jaw in Prostate Cancer Patients with Bone Metastases]. [前列腺癌骨转移患者抗吸收剂相关性颌骨骨坏死的危险因素]。

Acta Urologica Japonica Pub Date : 2023-05-01 DOI: 10.14989/ActaUrolJap_69_5_125

Kana Ito, Heisuke Iijima, Masatoshi Kumagai, Ryo Yabusaki, Yusuke Muro, Yusuke Shiraishi, Masaaki Imamura, Koji Yoshimura

{"title":"[Risk Factors of Antiresorptive Agent-Related Osteonecrosis of the Jaw in Prostate Cancer Patients with Bone Metastases].","authors":"Kana Ito, Heisuke Iijima, Masatoshi Kumagai, Ryo Yabusaki, Yusuke Muro, Yusuke Shiraishi, Masaaki Imamura, Koji Yoshimura","doi":"10.14989/ActaUrolJap_69_5_125","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_5_125","url":null,"abstract":"Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is a severe adverse event associated with use of bone resorption inhibitors (BRIs), such as zoledronic acid and denosumab. Based on the results of phase 3 clinical trials for BRIs, the frequency of ARONJ is reported to be 1 to 2%, but the actual frequency could be higher. We investigated 173 patients with prostate cancer with bone metastases who were treated either with zoledronic acid or denosumab at our hospital between July 2006 and June 2020. ARONJ occurred in 13 patients (8%); i.e., ten out of 159 patients (6%) who were treated with zoledronic acid, and three out of 14 patients (21%) who were treated with denosumab. Multivariate analysis showed that longer duration of BRI exposure and dental treatment before the initiation of BRI are associated with risk of ARONJ. ARONJ is associated with decreased mortality but the association is not significant. Generally, the occurrence of ARONJ may be underestimated; therefore, further studies are warranted to determine the actual frequency of ARONJ.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 5","pages":"125-129"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9988176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Primary Signet Ring Cell Carcinoma of the Urinary Bladder Showing Effectiveness of Chemotherapy with Gemcitabine and Cisplatin]. 【原发性膀胱印戒细胞癌1例吉西他滨联合顺铂化疗疗效观察】。

Acta Urologica Japonica Pub Date : 2023-04-01 DOI: 10.14989/ActaUrolJap_69_4_107

Makoto Ishii, Yoshiyuki Yamamoto, Akihiro Yoshimura, Takuji Hayashi, Norihiko Kawamura, Akira Nagahara, Yasutomo Nakai, Masashi Nakayama, Kazuo Nishimura

{"title":"[A Case of Primary Signet Ring Cell Carcinoma of the Urinary Bladder Showing Effectiveness of Chemotherapy with Gemcitabine and Cisplatin].","authors":"Makoto Ishii, Yoshiyuki Yamamoto, Akihiro Yoshimura, Takuji Hayashi, Norihiko Kawamura, Akira Nagahara, Yasutomo Nakai, Masashi Nakayama, Kazuo Nishimura","doi":"10.14989/ActaUrolJap_69_4_107","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_4_107","url":null,"abstract":"A 55-year-old female presented to the hospital with a complaint of gross hematuria. Transurethral resection of bladder tumor was performed. The specimens pathologically showed signet ring cells and no urothelial carcinoma components. Magnetic resonance imaging and computed tomographic (CT) scan revealed bladder tumor, cervical metastasis, bilateral ovarian metastasis, and multiple lymph node metastasis. She was diagnosed with a primary signet ring cell carcinoma of the urinary bladder with cT3bN2M1, and was treated with chemotherapy of gemcitabine and cisplatin combination (GC). After 2 cycles of GC, the value of CEA which was elevated to 106 ng/ml before treatment, became negative. CT scan showed that her disease had successfully responded to the chemotherapy, and remained efficacious till the end of 6 cycles. The patient subsequently received 1 cycle of gemcitabine and nedaplatin and 3 cycles of avelumab due to renal insufficiency. Yet, 14 months after diagnosis, cerebellar metastases appeared and the patient died of meningeal carcinomatosis.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 4","pages":"107-112"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Pelvic Reconstruction in Abdominal Trachelectomy and Bilateral Salpingo-Oophorectomy for Occult Uterine Endometrial Cancer Found in Specimens Removed in the Context of Laparoscopic Sacrocolpopexy]. [腹腔输卵管切除术和双侧输卵管-卵巢切除术在腹腔镜骶阴道固定术中发现的隐性子宫内膜癌的盆腔重建]。

Acta Urologica Japonica Pub Date : 2023-04-01 DOI: 10.14989/ActaUrolJap_69_4_117

Yasutoshi Yoshiyama, Tomoka Obuchi, Shiho Oide, Ippei Oiwa, Mika Nagae, Kojiro Nishio, Shino Tokiwa, Takuto Matsuura, Yugo Sawada, Tokumasa Hayashi, Isao Otsuka, Yasuhide Kitagawa, Masayoshi Nomura

{"title":"[Pelvic Reconstruction in Abdominal Trachelectomy and Bilateral Salpingo-Oophorectomy for Occult Uterine Endometrial Cancer Found in Specimens Removed in the Context of Laparoscopic Sacrocolpopexy].","authors":"Yasutoshi Yoshiyama, Tomoka Obuchi, Shiho Oide, Ippei Oiwa, Mika Nagae, Kojiro Nishio, Shino Tokiwa, Takuto Matsuura, Yugo Sawada, Tokumasa Hayashi, Isao Otsuka, Yasuhide Kitagawa, Masayoshi Nomura","doi":"10.14989/ActaUrolJap_69_4_117","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_4_117","url":null,"abstract":"In the patients undergoing pelvic organ prolapse (POP) repairs, the incidence of occult uterine endometrial cancer is low and there is no established management procedure for preoperative cancer screening. We report a case of pelvic reconstruction in abdominal trachelectomy and bilateral salpingo-oophorectomy for occult uterine endometrial cancer found in specimens removed in the context of laparoscopic sacrocolpopexy (LSC). A 70-year-old woman presented to our center with cystocele. She underwent LSC and laparoscopic supracervical hysterectomy. She had no atypical genital bleeding; and, transvaginal ultrasound, pelvic plane magnetic resonance imaging and cervical cytology showed no evidence of malignancy. However, the pathological examination showed uterine endometrial cancer. She underwent trachelectomy, bilateral salpingo-oophorectomy and pelvic lymph node dissection. A part of mesh was removed with a cervical stamp, but the remaining mesh was sewn together. At 5 months after the operation, no recurrence of uterine endometrial cancer and POP was seen.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 4","pages":"117-120"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Primary Leiomyosarcoma of the Epididymis : A Case Report]. 附睾原发性平滑肌肉瘤1例。

Acta Urologica Japonica Pub Date : 2023-04-01 DOI: 10.14989/ActaUrolJap_69_4_113

Ryota Ikadai, Hideki Kanda, Susumu Watanabe, Hiroshi Matsuura

引用次数: 0

[A Study of Factors Affecting Febrile Urinary Tract Infection Following Ureterorenoscopic Lithotripsy]. 输尿管镜碎石术后发热性尿路感染的影响因素研究

Acta Urologica Japonica Pub Date : 2023-04-01 DOI: 10.14989/ActaUrolJap_69_4_101

Shunsuke Hori, Tomoya Yamasaki, Kei Fujio, Hideo Otsuki, Koichi Nakajima, Yozo Mitsui

{"title":"[A Study of Factors Affecting Febrile Urinary Tract Infection Following Ureterorenoscopic Lithotripsy].","authors":"Shunsuke Hori, Tomoya Yamasaki, Kei Fujio, Hideo Otsuki, Koichi Nakajima, Yozo Mitsui","doi":"10.14989/ActaUrolJap_69_4_101","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_4_101","url":null,"abstract":"Febrile urinary tract infection (f-UTI) is a common complication after ureterorenoscopic lithotripsy (URSL) but is sometimes lethal. In this article, we analyzed the factors of post URSL f-UTI. We retrospectively evaluated the association between the development of f-UTI and patients, stones, and perioperative factors in 695 cases in which URSL was performed at our institution from September 2015 to 2018. Seventy-six of the 695 patients (10.9%) had postoperative f-UTI. Elderly (p＝0.013), female (p＝0.02), and hypertension (p＝0.001) patients had significantly higher rates of f-UTI. Renal stone (p＝0.001) cases showed significantly higher rates of f-UTI. Preoperative urine positive culture (p＝0.045), preoperative f-UTI (p＜0.001), URSL procedure using flexible ureteroscopy (p＝0.048), non-stone-free (p＝0.006), long operation time (p＝0.011), preoperative urinary stent insertion due to preoperative f-UTI (p＜0.001), were factors associated with post-operative f-UTI. Multivariate analysis revealed that hypertension (OR＝2.08, p＝0.008) and preoperative f-UTI (OR＝3.739, p＝0.033) were independent factors of postoperative f-UTI. Patients with hypertension or preoperative f-UTI should be managed more carefully during the perioperative period, suspecting that they are more likely to develop postoperative f-UTI.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 4","pages":"101-106"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9462949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Male Refractory Urethral Diverticular Abscess Requiring Transurethral Fenestration : A Case Report]. 男性难治性尿道憩室脓肿需经尿道开窗1例。

Acta Urologica Japonica Pub Date : 2023-03-01 DOI: 10.14989/ActaUrolJap_69_3_91

Noriyuki Makita, Takaya Murashima, Norihiko Masuda, Nobuyuki Nishikawa, Takahito Sohma, Takehiko Segawa

引用次数: 0

[Retroperitoneal Dedifferentiated Liposarcoma with No Recurrence after 5 Years of Postoperative Radiation Therapy --A Case Report-]. [腹膜后去分化脂肪肉瘤术后5年放疗无复发- 1例报告]。

Acta Urologica Japonica Pub Date : 2023-03-01 DOI: 10.14989/ActaUrolJap_69_3_79

Chika Hosokawa, Ai Kawaguchi, Shizuka Kiuchi, Akira Suzuki, Hisayasu Nagakura, Nobuo Shinohara, Kunihiko Tsuchiya

{"title":"[Retroperitoneal Dedifferentiated Liposarcoma with No Recurrence after 5 Years of Postoperative Radiation Therapy --A Case Report-].","authors":"Chika Hosokawa, Ai Kawaguchi, Shizuka Kiuchi, Akira Suzuki, Hisayasu Nagakura, Nobuo Shinohara, Kunihiko Tsuchiya","doi":"10.14989/ActaUrolJap_69_3_79","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_3_79","url":null,"abstract":"A 49-year-old woman presented to our hospital with right lower back pain and epigastric pressure. A computed tomographic scan showed a 12×7×20 cm retroperitoneal mass comprising fatty components and contrast areas around the right kidney. Based on the results, a right retroperitoneal liposarcoma was suspected. Thus, right retroperitoneal tumor resection combined with right kidney resection was performed. Instances of tumor adhesion were found in the ascending colon, duodenum, and the iliopsoas muscle, which could be dissected ; therefore, combined resection of the intestinal tract was not performed. The resected tumor was found to be mixed with dedifferentiated and well-differentiated components and was diagnosed as dedifferentiated liposarcoma. Due to the presence of positive margins, the patient received 50 Gy in 25 fractions of radiation therapy to the right side of the retroperitoneum as postoperative adjuvant therapy. During the irradiation period, vomiting and anorexia were observed as adverse events. Five years have passed since the surgery, and no local recurrence or late complications due to radiation have been observed. Although dedifferentiated liposarcoma is a highly malignant histological type with a very high local recurrence rate, no adjuvant therapy has been established. Some reports have suggested that postoperative radiation therapy for retroperitoneal sarcoma is effective in terms of survival and local control. However, there are no reports of prospective clinical trials, and the evidence is expected to widen in the near future.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 3","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9284165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Intra-Abdominal Testicular Cancer Occurring from an Overlooked Intra-Abdominal Testis in Undescended Testicular Surgery]. [1例腹内睾丸癌发生于隐性睾丸手术中被忽视的腹内睾丸]。

Acta Urologica Japonica Pub Date : 2023-03-01 DOI: 10.14989/ActaUrolJap_69_3_85

Yasuaki Katsunaga, Koji Nishizawa, Kodai Hattahara, Toru Yoshida, Atsushi Sengiku

{"title":"[A Case of Intra-Abdominal Testicular Cancer Occurring from an Overlooked Intra-Abdominal Testis in Undescended Testicular Surgery].","authors":"Yasuaki Katsunaga, Koji Nishizawa, Kodai Hattahara, Toru Yoshida, Atsushi Sengiku","doi":"10.14989/ActaUrolJap_69_3_85","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_3_85","url":null,"abstract":"Here, we report an adult case of intra-abdominal testicular cancer after surgical treatment of an undescended testis in infancy. A 36-year-old male patient was accidentally diagnosed with a tumor in the pelvic cavity by ultrasonographic examination. He had hematuria and the human chorionic gonadotropin beta subunit level was slightly elevated. T2-weighedmagnetic resonance imaging revealed a well-defined and highly intense mass. Since these findings suggested intra-abdominal testicular cancer, laparoscopic surgery was performed to remove the mass. Laparoscopy revealed an intra-abdominal tumor accompanied by a looping vas deferens entering the left inguinal canal. The distal part of the looping vas had already been removed from the external inguinal ring. The pathological findings revealed a pT1 seminoma. The patient has been recurrence-free for 12 months. The present case implies the importance of careful investigation and treatment for intra-abdominal testicular cancer, since intra-abdominal testis might have been overlooked at the time of surgery for undescended testis.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 3","pages":"85-89"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9284164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pre-Operative Factors Affecting Trifecta Achievement in the Initial Series of Robot-Assisted Partial Nephrectomy]. [影响机器人辅助部分肾切除术初始系列中三节切除术效果的术前因素]。

Acta Urologica Japonica Pub Date : 2023-03-01 DOI: 10.14989/ActaUrolJap_69_3_73

Takahiro Aoki, Naoki Wada, Gaku Tamaki, Noriyuki Abe, Shin Kobayashi, Kotona Miyauchi, Mayumi Ishikawa, Shogo Makino, Masaya Nagabuchi, Hidehiro Kakizaki

{"title":"[Pre-Operative Factors Affecting Trifecta Achievement in the Initial Series of Robot-Assisted Partial Nephrectomy].","authors":"Takahiro Aoki, Naoki Wada, Gaku Tamaki, Noriyuki Abe, Shin Kobayashi, Kotona Miyauchi, Mayumi Ishikawa, Shogo Makino, Masaya Nagabuchi, Hidehiro Kakizaki","doi":"10.14989/ActaUrolJap_69_3_73","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_3_73","url":null,"abstract":"We investigated pre-operative factors affecting trifecta achievement in robot-assisted partial nephrectomy (RAPN). We retrospectively analyzed 81 patients who underwent RAPN from December 2016 to September 2021 with final malignant pathologies. Trifecta was defined as negative resection margin (RM),warm ischemic time (WIT) less than 25 minutes, and no severe perioperative complications (Clavien-Dindo＜III). Factors affecting trifecta achievement were analyzed using sex, age, body mass index, RENAL nephrometry score (low or moderate/high complexity), surgical approach (transabdominal or retroperitoneal), tumor diameter and surgical experiences of each surgeon. Negative RM, WIT less than 25 minutes, and no severe complications were obtained in 75 (93%), 65 (80%), and 79 patients (98%), respectively. The trifecta was achieved in 60 patients (74%). In multivariate regression analysis, surgical experience (OR:0.92, 95% CI : 0.86-0.99) was significantly associated with trifecta achievement. Receiver operating characteristic curve analysis identified 9 cases as the optimal cut-off values for the predication of trifecta achievement (AUC＝0.69,p ＝0.11). The achievement of WIT less than 25 minutes (65 vs 90%, p＜0.01) and trifecta (58 vs 84%,p ＜0.05) were significantly lower in surgical experiences less than 9 cases than in 9 or greater. We conclude that surgical experience in RAPN is an important factor affecting WIT and trifecta achievement in the initial series.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 3","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9284163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of m0CRPC after Hormone Therapy for Pelvic Lymph Node Metastasis in which Salvage RARP was Effective]. [1例盆腔淋巴结转移激素治疗后m0CRPC，挽救性RARP有效]。

Acta Urologica Japonica Pub Date : 2023-02-01 DOI: 10.14989/ActaUrolJap_69_2_59

Hidetoshi Kokubun, Masashi Kubota, Takanari Kambe, Yuta Mine, Hiroki Hagimoto, Ritsuki Yamaguchi, Shiori Murata, Noriyuki Makita, Yuto Hattori, Yohei Abe, Naofumi Tsutsumi, Toshinari Yamasaki, Koji Inoue, Mutsushi Kawakita

{"title":"[A Case of m0CRPC after Hormone Therapy for Pelvic Lymph Node Metastasis in which Salvage RARP was Effective].","authors":"Hidetoshi Kokubun, Masashi Kubota, Takanari Kambe, Yuta Mine, Hiroki Hagimoto, Ritsuki Yamaguchi, Shiori Murata, Noriyuki Makita, Yuto Hattori, Yohei Abe, Naofumi Tsutsumi, Toshinari Yamasaki, Koji Inoue, Mutsushi Kawakita","doi":"10.14989/ActaUrolJap_69_2_59","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_2_59","url":null,"abstract":"The patient was a 63-year-old man with biopsy Gleason score of 4＋5 prostate cancer with an initial prostate specific antigen level of (PSA) 51.2ng/ml. On imaging examination, extracapsular invasion, rectal invasion, and pararectal lymph node metastasis were found (cT4N1M0). After 4 years of androgen deprivation therapy, PSA decreased to 0.631ng/ml, and then increased gradually to1.2ng/ml. Computed tomographic scan showed that the primary tumor had shrunk and lymph node metastasis had disappeared; so salvage robot-assisted resection of the prostate (RARP) was performed for non-metastatic castration-resistant prostate cancer (m0CRPC). Since PSA decreased to an undetactable level, hormone therapy was terminated at 1 year. The patient remained recurrence-free for 3 years after surgery. RARP may be effective for m0CRPC, enabling discontinuation of androgen deprivation therapy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 2","pages":"59-62"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10837338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0