Acta Urologica Japonica最新文献

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[A Renal Leiomyoma --A Case Report-]. [肾雷肌瘤--病例报告--]。
Acta Urologica Japonica Pub Date : 2024-01-01 DOI: 10.14989/ActaUrolJap_70_1_7
Shohei Toyota, Taku Kato, Hidetoshi Ehara, Shigeyuki Sugie
{"title":"[A Renal Leiomyoma --A Case Report-].","authors":"Shohei Toyota, Taku Kato, Hidetoshi Ehara, Shigeyuki Sugie","doi":"10.14989/ActaUrolJap_70_1_7","DOIUrl":"10.14989/ActaUrolJap_70_1_7","url":null,"abstract":"<p><p>A 49-year-old female was incidentally found to have a left renal tumor during a medical check-up. The tumor was too small to be fully diagnosed using computed tomography (CT) or magnetic resonance imaging (MRI). Since it was small and showed a homogenous enhancement pattern on contrast-enhanced CT, which made it difficult for us to distinguish the malignancy of the tumor, we performed regular CT follow-up. On the fifth year of her regular follow-up, the tumor had grown apparently larger and showed a heterogenous enhancement pattern, which suggested a malignant tumor. Since the tumor was exophytic, we decided to perform a laparoscopic partial nephrectomy. The operation was performed without any serious complications, and her renal function remained unchanged. The histopathology of the tumor was leiomyoma. Here, we discuss the characteristics of this tumor and the role of immunohistopathology in the diagnosis.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 1","pages":"7-11"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139698484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Retrograde Ureteroscopic Lithotripsy with Ureteral Access Sheath Via Cutaneous Ureterostomy after Urinary Diversion : A Case Report]. [经皮输尿管造口术后使用输尿管入路鞘管逆行输尿管镜碎石术:病例报告]。
Acta Urologica Japonica Pub Date : 2024-01-01 DOI: 10.14989/ActaUrolJap_70_1_17
Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki
{"title":"[Retrograde Ureteroscopic Lithotripsy with Ureteral Access Sheath Via Cutaneous Ureterostomy after Urinary Diversion : A Case Report].","authors":"Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki","doi":"10.14989/ActaUrolJap_70_1_17","DOIUrl":"10.14989/ActaUrolJap_70_1_17","url":null,"abstract":"<p><p>A 65-year-old man presented with a history of rectal cancer 20 years prior that led to the development of a cutaneous ureterostomy and a colostomy. Subsequently, the patient was diagnosed with acute complicated pyelonephritis due to a right ureteral stone. After the placement of a single J ureteral stent in the right ureter for therapeutic management, the patient was referred to our institution for treatment of the right ureteral stone. An abdominal computed tomography (CT) revealed an 11×8 mm stone in the upper right ureter. A 10/12 Fr ureteral access sheath was inserted through the cutaneous ureterostomy and retrograde ureteroscopic lithotripsy was performed. Although a febrile urinary tract infection appeared postoperatively, the patient was discharged on the sixth postoperative day. At postoperative 1-month, CT showed no residual stones and no hydronephrosis. The use of a ureteral access sheath in performing retrograde ureteroscopic lithotripsy effectively managed the ureteral stone with cutaneous ureterostomy.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 1","pages":"17-19"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139698485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Two Cases of Ammonium Acid Urate Urinary Stones That Could Not Be Diagnosed by Dual-Energy Computed Tomography]. [两例无法通过双能量计算机断层扫描诊断的尿酸尿酸铵结石】。]
Acta Urologica Japonica Pub Date : 2024-01-01 DOI: 10.14989/ActaUrolJap_70_1_13
Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki
{"title":"[Two Cases of Ammonium Acid Urate Urinary Stones That Could Not Be Diagnosed by Dual-Energy Computed Tomography].","authors":"Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki","doi":"10.14989/ActaUrolJap_70_1_13","DOIUrl":"10.14989/ActaUrolJap_70_1_13","url":null,"abstract":"<p><p>We report two cases of ammonium acid urate stones that could not be diagnosed by dual-energy computed tomography (CT). Case 1: A 37-year-old female was referred to our hospital for a left kidney stone. She had a medical history of anorexia nervosa, Basedow's disease and hypoparathyroidism. Her height was 167 cm, weight 38 kg and body mass index (BMI) 13. 6. CT showed a left kidney stone measuring 18×12 mm. Dual-energy CT showed that the left kidney stone was composed of uric acid. Chemolysis by oral administration of alkaline citrate was attempted. Six months later, CT showed no improvement, and endoscopic combined intrarenal surgery (ECIRS) was performed. Stone analysis revealed pure ammonium acid urate. Case 2: A 42-year-old female was referred to our hospital because of right back pain. She had a medical history of ventricular septal defect and urolithiasis. Her height was 158 cm, weight 37 kg, and BMI 14.8. CT showed a right kidney stone measuring 16×12 mm. Dual-energy CT showed that the right kidney stone was composed of uric acid. Chemolysis by oral administration of alkaline citrate was attempted. Two months later, CT showed no improvement, and ECIRS was performed. Stone analysis revealed pure ammonium acid urate. It is difficult to differentiate uric acid stones and ammonium acid urate stones by dual-energy CT. Even when dual-energy CT suggests uric acid stones, ammonium acid urate stones should also be considered in thin young women and women with a history of anorexia nervosa.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139698486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cost-Effectiveness Analysis and Budget Impact Analysis of Enzalutamide for the Treatment of Metastatic Hormone-Sensitive Prostate Cancer]. [恩杂鲁胺治疗转移性激素敏感性前列腺癌的成本效益分析和预算影响分析]。
Acta Urologica Japonica Pub Date : 2023-12-01 DOI: 10.14989/ActaUrolJap_69_12_337
Keiko Asakawa, Koki Idehara, Atsushi Saito, Takeshi Mitomi, Ataru Igarashi
{"title":"[Cost-Effectiveness Analysis and Budget Impact Analysis of Enzalutamide for the Treatment of Metastatic Hormone-Sensitive Prostate Cancer].","authors":"Keiko Asakawa, Koki Idehara, Atsushi Saito, Takeshi Mitomi, Ataru Igarashi","doi":"10.14989/ActaUrolJap_69_12_337","DOIUrl":"10.14989/ActaUrolJap_69_12_337","url":null,"abstract":"<p><p>We conducted cost-effectiveness analysis and budget impact analysis for androgen deprivation therapy (ADT) plus enzalutamide (ENZ) on patients with metastatic hormone-sensitive prostate cancer (mHSPC) from the publicly-funded healthcare system perspective. Using a partitioned survival model, lifetime costs, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs) of ADT+ENZ were estimated against ADT alone, ADT plus abiraterone (ADT+ABI), and ADT plus apalutamide (ADT+APA). Total healthcare cost differences with and without ENZ in mHSPC therapy were estimated for the period from 2022 to 2026. Based on cost-effectiveness analysis, the ICER of ADT+ENZ versus ADT alone was estimated as ¥7.18 million/QALY gained. ADT+ABI and ADT+APA were dominated options (extended dominance). Budget impact analysis showed that incorporation of ENZ had a net budget impact of ¥57.19 billion, an 8.4% increase, over these 5 years. This amounted to a budgetary impact of ¥16,000 per patient per month at year 5. However, the number of patients with disease progressed to metastatic castration-resistant prostate cancer (mCRPC) would be reduced from 79,000 (without ENZ) to 65,000 (with ENZ), resulting in a 17% cost reduction within the mCRPC phase. In conclusion, ADT+ENZ would be a cost-effective option, at the willingness to pay threshold of ¥7.5 million/QALY gained. Introduction of ENZ in the mHSPC treatment would result in a marginal increase in the total budget. However, ENZ is also expected to provide clinical benefits in reducing the number of patients with disease that would otherwise progress to mCRPC during these 5 years, resulting in cost savings in this phase.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 12","pages":"337-361"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A Case of Metanephric Adenoma Treated with Robotic-Assisted Laparoscopic Partial Nephrectomy]. [机器人辅助腹腔镜肾部分切除术治疗肾上腺瘤一例]。
Acta Urologica Japonica Pub Date : 2023-12-01 DOI: 10.14989/ActaUrolJap_69_12_369
Kohei Segawa, Koichi Tsutahara, Kenji Tsutsui, Airi Miki, Teppei Wakita, Yuki Horibe, Masaru Tani, Yoichi Kakuta, Tetsuya Takao
{"title":"[A Case of Metanephric Adenoma Treated with Robotic-Assisted Laparoscopic Partial Nephrectomy].","authors":"Kohei Segawa, Koichi Tsutahara, Kenji Tsutsui, Airi Miki, Teppei Wakita, Yuki Horibe, Masaru Tani, Yoichi Kakuta, Tetsuya Takao","doi":"10.14989/ActaUrolJap_69_12_369","DOIUrl":"10.14989/ActaUrolJap_69_12_369","url":null,"abstract":"<p><p>A 53-year-old female patient was diagnosed with a left renal mass incidentally detected on an abdominal computed tomography (CT) scan. Further examination revealed a slightly contrast-enhancing mass 2.0 cm in diameter, in the left kidney on a contrast-enhanced CT scan. A diagnosis of left renal cell carcinoma (cT1aN0M0) was made and a robotic-assisted laparoscopic partial nephrectomy was performed. The excised tissue specimen exhibited a clearly circumscribed tumor. On hematoxylin eosin staining, the small uniform tumor cells appeared organized in glandular luminal arrangements, with lacking nuclear atypia and any malignant features. Immunostaining confirmed the diagnosis as metanephric adenoma, as indicated by positive results for WT1 and negative results for alpha-methylacyl-CoA race mase. Metanephric adenoma is an uncommon benign epithelial tumor of the kidney, which frequently poses a challenge in differential diagnosis with renal carcinoma on preoperative imaging. Pathologically, it can be challenging to differentiate from papillary renal cell carcinoma, and immunostaining can be used to effectively differentiate between the two entities.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 12","pages":"369-372"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ureteral Access Sheath Assisted Percutaneous Antegrade Ureteroscopic Lithotripsy for Impacted Ureteral Calculus]. [输尿管入口鞘辅助经皮前路输尿管镜碎石术治疗输尿管结石]。
Acta Urologica Japonica Pub Date : 2023-12-01 DOI: 10.14989/ActaUrolJap_69_12_363
Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki
{"title":"[Ureteral Access Sheath Assisted Percutaneous Antegrade Ureteroscopic Lithotripsy for Impacted Ureteral Calculus].","authors":"Tetsuo Fukuda, Ryo Kawahata, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki","doi":"10.14989/ActaUrolJap_69_12_363","DOIUrl":"10.14989/ActaUrolJap_69_12_363","url":null,"abstract":"<p><p>We retrospectively evaluated the safety and effectiveness of ureteral access sheath-assisted percutaneous antegrade ureteroscopic lithotripsy in treating ureteral calculus. Between January 2016 and April 2022, 28 patients with ureteral calculus received ureteral access sheath-assisted percutaneous antegrade ureteroscopic lithotripsy. At postoperative 1 month, a plain computed tomography (CT) and kidney ureter bladder X-ray (KUB) were performed to assess stone fragmentation and hydronephrosis. According to postoperative imaging, stone-free was defined as residual fragments 4 mm or less on KUB and 2 mm or less on CT. The mean stone size was 16.3 mm (3-43 mm). The mean stone volume was 1.91 ml (0.13-6.1 ml). The mean operative time was 140 min (60-222 min). Stone-free rate (SFR) was 89.3% on KUB, and 82.1% on CT. Three patients (10.7%) had postoperative fever greater than 38.5°C. There were no complications of grade III or higher according to the modified Clavien-Dindo classification. In the Ellenbogen classification, improvement was observed in hydronephrosis of Grade II or lower. Improvement was also observed in cases with Grade III hydronephrosis. However, due to the presence of residual renal atrophy, there was no change in the classification. The preoperative eGFR was 63 ml/min/1.73 m² (36-101 ml/min/1.73 m²) and the postoperative eGFR was not improved. We conclude that ureteral access sheath-assisted percutaneous antegrade ureteroscopic lithotripsy is effective for treating impacted ureteral calculus.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 12","pages":"363-368"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efficacy of Recombinant Thrombomodulin for Sepsis-Associated Disseminated Intravascular Coagulation Caused by Urinary Tract Infections]. 重组凝血调节蛋白治疗尿路感染所致脓毒症相关性弥散性血管内凝血的疗效研究。
Acta Urologica Japonica Pub Date : 2023-11-01 DOI: 10.14989/ActaUrolJap_69_11_309
Akira Tachibana, Kota Iida, Yoshitaka Itami, Masaya Hashimura, Yuta Toyoshima, Yukinari Hosokawa, Kiyohide Fujimoto
{"title":"[Efficacy of Recombinant Thrombomodulin for Sepsis-Associated Disseminated Intravascular Coagulation Caused by Urinary Tract Infections].","authors":"Akira Tachibana, Kota Iida, Yoshitaka Itami, Masaya Hashimura, Yuta Toyoshima, Yukinari Hosokawa, Kiyohide Fujimoto","doi":"10.14989/ActaUrolJap_69_11_309","DOIUrl":"10.14989/ActaUrolJap_69_11_309","url":null,"abstract":"<p><p>Severe urinary tract infections occasionally cause sepsis and disseminated intravascular coagulation (DIC). We examined the efficacy of recombinant thrombomodulin (rTM) for treating DIC caused by urosepsis. We enrolled 40 patients who were diagnosed with DIC caused by urosepsis at our hospital between April 2018 and May 2022. Twenty-six patients were treated with rTM (rTM group), while 14 patients did not receive rTM (non-rTM group). The DIC score before treatment in the rTM group was significantly higher than that in the non-rTM group (P<0.01). There was no significant difference in disease-specific survival between the two groups. There was a significant improvement in DIC scores on days 1-3 after administering rTM. However, the duration of DIC in the rTM group was significantly longer than that in the non-rTM group (P=0.038). The administration of rTM may have benefits in patients with DIC caused by urosepsis.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 11","pages":"309-314"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Testicular Malignant Sertoli Cell Tumor with Long-Term Survival After Pulmonary Metastasectomy: A Case Report]. [睾丸恶性支持细胞肿瘤肺转移切除术后长期生存:一例报告]。
Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_295
Noriyuki Makita, Kazuma Hiramatsu, Yuki Kamiyama, Naofumi Tsutsumi, Toru Yoshida, Yoko Iwasa, Yoji Urata, Takehiko Segawa
{"title":"[Testicular Malignant Sertoli Cell Tumor with Long-Term Survival After Pulmonary Metastasectomy: A Case Report].","authors":"Noriyuki Makita,&nbsp;Kazuma Hiramatsu,&nbsp;Yuki Kamiyama,&nbsp;Naofumi Tsutsumi,&nbsp;Toru Yoshida,&nbsp;Yoko Iwasa,&nbsp;Yoji Urata,&nbsp;Takehiko Segawa","doi":"10.14989/ActaUrolJap_69_10_295","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_295","url":null,"abstract":"<p><p>A 45-year-old man was referred to our hospital with a complaint of right scrotal discomfort. With a diagnosis of testicular tumor, right orchiectomy was performed. The tumor was histologically diagnosed as malignant Sertoli cell tumor pT1N0M0. A pulmonary nodule appeared, 53 months after the operation, and increased in size there after. Thoracoscopic left upper lobectomy was performed 64 months after the operation, and the pathological diagnosis was metastasis of malignant Sertoli cell tumor. No recurrence has been observed for 94 months after the resection of the metastatic lesion.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"295-298"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Relationship Between Prognosis and Duration of Drug Holidays after Docetaxel Therapy for Castration-Resistant Prostate Cancer]. [多西他赛治疗耐Castion-Ristant前列腺癌癌症后的预后与停药时间的关系]。
Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_269
Kenta Onishi, Nobumichi Tanaka, Yasushi Nakai, Norimi Takamatsu, Tatsuki Miyamoto, Mitsuru Tomizawa, Takuto Shimizu, Shunta Hori, Makito Miyake, Kiyohide Fujimoto
{"title":"[The Relationship Between Prognosis and Duration of Drug Holidays after Docetaxel Therapy for Castration-Resistant Prostate Cancer].","authors":"Kenta Onishi,&nbsp;Nobumichi Tanaka,&nbsp;Yasushi Nakai,&nbsp;Norimi Takamatsu,&nbsp;Tatsuki Miyamoto,&nbsp;Mitsuru Tomizawa,&nbsp;Takuto Shimizu,&nbsp;Shunta Hori,&nbsp;Makito Miyake,&nbsp;Kiyohide Fujimoto","doi":"10.14989/ActaUrolJap_69_10_269","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_269","url":null,"abstract":"<p><p>The next treatment strategy after drug holidays following docetaxel (DTX) therapy for patients with castration-resistant prostate cancer (CRPC) is unclear. This study investigated the relationship between the duration of drug holidays and prognosis after DTX therapy. This study retrospectively assessed 26 patients treated with DTX in our hospital. Overall survival duration was significantly longer in the long-term withdrawal group (duration of drug holidays ≥6 months) than in the short-term withdrawal group (duration of drug holidays <6 months) (P=0.015). Similarly, progression-free survival duration was significantly longer in the long-term withdrawal group than in the short-term withdrawal group (P=0.008). The short-term withdrawal group had a significantly lower body mass index (P=0.009) and higher prostate-specific antigen (PSA) (P=0.017) at the initiation of DTX therapy, higher PSA nadir during DTX therapy (P=0.009), and higher PSA at the end of DTX therapy (P=0.022), compared to the long-term withdrawal group. This study suggests that the optimal opportunity to introduce DXT therapy is when the patients with CRPC are physically able to tolerate chemotherapy and their tumor volume remains a lower burden. This may provide a clinical benefit, longer drug holidays, and a better prognosis.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"269-277"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of the Effects of Long-Term Indwelling Ureteral Stents on Preserving Renal Parenchyma and Function in Patients with Ureteral Stenosis]. [评价长期留置输尿管支架对保留输尿管狭窄患者肾实质和功能的影响]。
Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_279
Tomohiro Toyota, Tomohiro Yoshikawa, Toshiaki Tanaka, Kohei Hashimoto, Ko Kobayashi, Naoya Masumori
{"title":"[Evaluation of the Effects of Long-Term Indwelling Ureteral Stents on Preserving Renal Parenchyma and Function in Patients with Ureteral Stenosis].","authors":"Tomohiro Toyota,&nbsp;Tomohiro Yoshikawa,&nbsp;Toshiaki Tanaka,&nbsp;Kohei Hashimoto,&nbsp;Ko Kobayashi,&nbsp;Naoya Masumori","doi":"10.14989/ActaUrolJap_69_10_279","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_279","url":null,"abstract":"<p><p>Although ureteral stenting is a common conservative treatment for ureteral stricture, it is unclear whether a long-term indwelling ureteral stent protects the kidney against parenchymal atrophy and functional deterioration. In this study, we evaluated the changes in renal parenchymal thickness (RPT) and estimated the glomerular filtration rates (eGFR) in patients with indwelling ureteral stents for one year or more. As a control, we also evaluated changes in RPT associated with indwelling percutaneous nephrostomy (PNS) for one year or more. Polymer ureteral stents were used and replaced every three months. RPT was measured using computed tomography (CT). Totally, 69 renal units in 55 patients with baseline and follow up CT scans available were enrolled. The median follow-up period was 29 months. The etiologies of ureteral obstruction were malignant and benign disease in 27 and 28, respectively. RPT was reduced obviously in most cases. At 1 year, the median reduction rate of RPT was 17.3% in unilateral cases, which was significantly higher than that in the healthy contralateral kidney. There was a strong correlation between eGFR and total RPT including the contralateral kidney. The reduction rate of RPT in kidneys with ureteral stents including bilateral cases was also significantly higher than that in 39 renal units of 35 patients with PNS. The results of this study suggest that the long-term efficacy of indwelling ureteral stents in preserving renal function is limited. Regular imaging may be essential to evaluate the residual renal function.</p>","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"279-287"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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