Acta Urologica Japonica最新文献_第9页

[Efficacy of Recombinant Thrombomodulin for Sepsis-Associated Disseminated Intravascular Coagulation Caused by Urinary Tract Infections]. 重组凝血调节蛋白治疗尿路感染所致脓毒症相关性弥散性血管内凝血的疗效研究。

Acta Urologica Japonica Pub Date : 2023-11-01 DOI: 10.14989/ActaUrolJap_69_11_309

Akira Tachibana, Kota Iida, Yoshitaka Itami, Masaya Hashimura, Yuta Toyoshima, Yukinari Hosokawa, Kiyohide Fujimoto

引用次数: 0

[Testicular Malignant Sertoli Cell Tumor with Long-Term Survival After Pulmonary Metastasectomy: A Case Report]. [睾丸恶性支持细胞肿瘤肺转移切除术后长期生存：一例报告]。

Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_295

Noriyuki Makita, Kazuma Hiramatsu, Yuki Kamiyama, Naofumi Tsutsumi, Toru Yoshida, Yoko Iwasa, Yoji Urata, Takehiko Segawa

引用次数: 0

[The Relationship Between Prognosis and Duration of Drug Holidays after Docetaxel Therapy for Castration-Resistant Prostate Cancer]. [多西他赛治疗耐Castion-Ristant前列腺癌癌症后的预后与停药时间的关系]。

Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_269

Kenta Onishi, Nobumichi Tanaka, Yasushi Nakai, Norimi Takamatsu, Tatsuki Miyamoto, Mitsuru Tomizawa, Takuto Shimizu, Shunta Hori, Makito Miyake, Kiyohide Fujimoto

{"title":"[The Relationship Between Prognosis and Duration of Drug Holidays after Docetaxel Therapy for Castration-Resistant Prostate Cancer].","authors":"Kenta Onishi, Nobumichi Tanaka, Yasushi Nakai, Norimi Takamatsu, Tatsuki Miyamoto, Mitsuru Tomizawa, Takuto Shimizu, Shunta Hori, Makito Miyake, Kiyohide Fujimoto","doi":"10.14989/ActaUrolJap_69_10_269","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_269","url":null,"abstract":"The next treatment strategy after drug holidays following docetaxel (DTX) therapy for patients with castration-resistant prostate cancer (CRPC) is unclear. This study investigated the relationship between the duration of drug holidays and prognosis after DTX therapy. This study retrospectively assessed 26 patients treated with DTX in our hospital. Overall survival duration was significantly longer in the long-term withdrawal group (duration of drug holidays ≥6 months) than in the short-term withdrawal group (duration of drug holidays ＜6 months) (P＝0.015). Similarly, progression-free survival duration was significantly longer in the long-term withdrawal group than in the short-term withdrawal group (P＝0.008). The short-term withdrawal group had a significantly lower body mass index (P＝0.009) and higher prostate-specific antigen (PSA) (P＝0.017) at the initiation of DTX therapy, higher PSA nadir during DTX therapy (P＝0.009), and higher PSA at the end of DTX therapy (P＝0.022), compared to the long-term withdrawal group. This study suggests that the optimal opportunity to introduce DXT therapy is when the patients with CRPC are physically able to tolerate chemotherapy and their tumor volume remains a lower burden. This may provide a clinical benefit, longer drug holidays, and a better prognosis.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"269-277"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Evaluation of the Effects of Long-Term Indwelling Ureteral Stents on Preserving Renal Parenchyma and Function in Patients with Ureteral Stenosis]. [评价长期留置输尿管支架对保留输尿管狭窄患者肾实质和功能的影响]。

Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_279

Tomohiro Toyota, Tomohiro Yoshikawa, Toshiaki Tanaka, Kohei Hashimoto, Ko Kobayashi, Naoya Masumori

{"title":"[Evaluation of the Effects of Long-Term Indwelling Ureteral Stents on Preserving Renal Parenchyma and Function in Patients with Ureteral Stenosis].","authors":"Tomohiro Toyota, Tomohiro Yoshikawa, Toshiaki Tanaka, Kohei Hashimoto, Ko Kobayashi, Naoya Masumori","doi":"10.14989/ActaUrolJap_69_10_279","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_279","url":null,"abstract":"Although ureteral stenting is a common conservative treatment for ureteral stricture, it is unclear whether a long-term indwelling ureteral stent protects the kidney against parenchymal atrophy and functional deterioration. In this study, we evaluated the changes in renal parenchymal thickness (RPT) and estimated the glomerular filtration rates (eGFR) in patients with indwelling ureteral stents for one year or more. As a control, we also evaluated changes in RPT associated with indwelling percutaneous nephrostomy (PNS) for one year or more. Polymer ureteral stents were used and replaced every three months. RPT was measured using computed tomography (CT). Totally, 69 renal units in 55 patients with baseline and follow up CT scans available were enrolled. The median follow-up period was 29 months. The etiologies of ureteral obstruction were malignant and benign disease in 27 and 28, respectively. RPT was reduced obviously in most cases. At 1 year, the median reduction rate of RPT was 17.3% in unilateral cases, which was significantly higher than that in the healthy contralateral kidney. There was a strong correlation between eGFR and total RPT including the contralateral kidney. The reduction rate of RPT in kidneys with ureteral stents including bilateral cases was also significantly higher than that in 39 renal units of 35 patients with PNS. The results of this study suggest that the long-term efficacy of indwelling ureteral stents in preserving renal function is limited. Regular imaging may be essential to evaluate the residual renal function.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"279-287"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Left Renal Cell Carcinoma with Renal Arteriovenous Fistula and Multiple Vascular Malformation Undergoing Nephrectomy]. [左肾细胞癌合并肾动静脉瘘和多血管畸形一例肾切除术]。

Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_289

Takanori Hayase, Satoshi Washino, Hiroki Yagi, Shozaburo Mayumi, Kai Yazaki, Yuki Nakamura, Kimitoshi Saito, Akihiro Sawada, Masahiro Hiruta, Koichi Tamai, Tomoaki Miyagawa

{"title":"[A Case of Left Renal Cell Carcinoma with Renal Arteriovenous Fistula and Multiple Vascular Malformation Undergoing Nephrectomy].","authors":"Takanori Hayase, Satoshi Washino, Hiroki Yagi, Shozaburo Mayumi, Kai Yazaki, Yuki Nakamura, Kimitoshi Saito, Akihiro Sawada, Masahiro Hiruta, Koichi Tamai, Tomoaki Miyagawa","doi":"10.14989/ActaUrolJap_69_10_289","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_289","url":null,"abstract":"A 69-year-old woman was referred to our hospital for the treatment of a left renal tumor found by computed tomography (CT) during examination for microscopic hematuria. Contrast-enhanced CT showed a 5 cm tumor in the inferior pole of the left kidney. Left renal cell carcinoma (RCC) (cT1bN0M0) was suspected. In addition, the left renal and gonadal veins were dilated and enhanced in an arterial phase; renal arteriovenous fistula (RAVF) was suspected. Moreover, there were multiple focal arterial dilatations, suggesting the presence of multiple vascular malformation. Hereditary aortic disease, including vascular Ehlers-Danlos syndrome (vEDS), was a concern. In general, surgery is not recommended for patients with vEDS, due to vascular fragility. As such, a panel analysis of genes for hereditary aortic diseases, including vEDS, was performed; no pathogenic variants in candidate genes including COL3A1 were identified. After detailed discussions with the patient, she underwent a left nephrectomy, following transcatheter arterial embolization (TAE) of the left renal artery. We prepared a balloon catheter for aortic occlusion as a preventative measure for massive bleeding; this was not the case, as only a small amount of intraoperative bleeding occurred. Thus, the nephrectomy was performed successfully without using the balloon catheter. The patient recovered uneventfully and was discharged on day 8. Pathological examination showed clear-cell RCC (pT1a) and a RAVF near the tumor. Herein we report this case of left RCC with RAVF and multiple arterial malformation, which was successfully managed by evaluating preoperative risks with a genetic test, followed by TAE of the renal artery and open nephrectomy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"289-294"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Urological Comorbidities in an HIV-Infected Patient: A Case Report]. [一例HIV感染患者的泌尿系统并发症：病例报告]。

Acta Urologica Japonica Pub Date : 2023-10-01 DOI: 10.14989/ActaUrolJap_69_10_299

Yohei Ueki, Ko Kobayashi, Kohei Hashimoto, Toshiaki Tanaka, Hiromi Fujita, Naoya Masumori

{"title":"[Urological Comorbidities in an HIV-Infected Patient: A Case Report].","authors":"Yohei Ueki, Ko Kobayashi, Kohei Hashimoto, Toshiaki Tanaka, Hiromi Fujita, Naoya Masumori","doi":"10.14989/ActaUrolJap_69_10_299","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_10_299","url":null,"abstract":"We report a case of a patient who developed several urological comorbidities associated with HIV infection. A 53-year-old male was diagnosed with HIV infection and AIDS. After 13 years, microhematuria was found and computed tomography (CT) revealed urolithiasis and a left renal tumor suspected of being renal cell carcinoma. Initially, he underwent transurethral lithotripsy. Stone analysis indicated that the stone was made of atazanavir. Then he received laparoscopic left partial nephrectomy. The pathological diagnosis was papillary type 2 renal cell carcinoma. Three years later, follow-up CT revealed a right renal pelvic tumor. Since right ureteroscopy showed that the tumor was papillary we diagnosed it as renal pelvic cancer and decided to perform laparoscopic right radical nephroureterectomy. His renal pelvic tumor was determined to be urothelial carcinoma by the pathological diagnosis. Intravesical recurrence occurred twice after the nephroureterectomy. His renal function gradually deteriorated during follow-up and we suspected that HIV nephrosis was one of the reasons for the deterioration. Hemodialysis was initiated at the age of 71.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 10","pages":"299-303"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71427656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Testicular Cancer with Solitary Iliac Bone Metastasis]. [睾丸癌症伴孤立性髂骨转移1例]。

Acta Urologica Japonica Pub Date : 2023-09-01 DOI: 10.14989/ActaUrolJap_69_9_259

Hajime Miyata, Takashige Abe, Naoya Iwahara, Hiroshi Kikuchi, Hiroki Chiba, Ryuji Matsumoto, Takahiro Osawa, Hiroshi Tanaka, Ken Morita, Tomoko Mitsuhashi, Nobuo Shinohara

{"title":"[A Case of Testicular Cancer with Solitary Iliac Bone Metastasis].","authors":"Hajime Miyata, Takashige Abe, Naoya Iwahara, Hiroshi Kikuchi, Hiroki Chiba, Ryuji Matsumoto, Takahiro Osawa, Hiroshi Tanaka, Ken Morita, Tomoko Mitsuhashi, Nobuo Shinohara","doi":"10.14989/ActaUrolJap_69_9_259","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_69_9_259","url":null,"abstract":"A 23-year-old male was aware of pain around his left hip joint and visited a nearby orthopedic clinic. Swelling of the right testis was pointed out, and a testicular tumor was suspected. He was referred to the urology department of a local hospital. Blood analysis showed an increase of α-fetoprotein (AFP) (3,620 ng/ml). Computed tomographic (CT) -scan revealed a left iliac bone metastasis and morbid fracture. Right radical inguinal orchiectomy was performed. The pathological examination revealed mixed germ cell tumor (embryonic carcinoma and immature teratoma: 70%, seminoma: 30%). The diagnosis was non-seminomatous germ cell tumor, stage IIIc, and poor risk on the International Germ Cell Consensus Classification. After one cycle of a bleomycin, etoposide and cisplatinum (BEP) regimen, he was referred to our hospital. After a total of 4 cycles of BEP, AFP was normalized. Denosumab was also administered monthly. The CT-scan showed a reduction of bone metastasis and recovery of ossification. Bone biopsy did not show viable tumor cells. Because extirpation of the remaining mass would require resection of the left part of the pelvic bone with significant functional loss of the left limb, we performed close follow-up after an additional 2 courses of the etoposide and cisplatin regimen. The patient is currently alive without recurrence at 45 months after the last systemic chemotherapy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 9","pages":"259-264"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41137292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Idiopathic Thrombocytopenia Purpura After Pembrolizumab Treatment Against Locally Recurrent Bladder Cancer : A Case Report]. [彭布罗珠单抗治疗局部复发性膀胱癌症后特发性血小板减少性紫癜：一例报告]。

Acta Urologica Japonica Pub Date : 2023-09-01 DOI: 10.14989/ActaUrolJap_69_9_255

Yuna Hattori, Manabu Kato, Tetsuya Imamura, Souta Inaba, Takashi Terabe, Momoko Kato, Shinichiro Higashi, Takeshi Sasaki, Satoru Masui, Yuko Yoshio, Kouhei Nishikawa, Katsunori Uchida, Takahiro Inoue

引用次数: 0

[Occurrence of Distant Metastasis During Bladder Presevation in T1 high-grade Bladder Cancer: Report of Three Cases]. [T1高级别膀胱癌症术前膀胱远端转移的发生：附3例报告]。

Acta Urologica Japonica Pub Date : 2023-09-01 DOI: 10.14989/ActaUrolJap_69_9_249

Chul Jang Kim, Haruna Ide, Masatoshi Nakamura, Eiki Hanada

{"title":"[Occurrence of Distant Metastasis During Bladder Presevation in T1 high-grade Bladder Cancer: Report of Three Cases].","authors":"Chul Jang Kim, Haruna Ide, Masatoshi Nakamura, Eiki Hanada","doi":"10.14989/ActaUrolJap_69_9_249","DOIUrl":"10.14989/ActaUrolJap_69_9_249","url":null,"abstract":"We report three patients with T1 high-grade (HG) bladder cancer who suffered from distant metastasis during bladder preservation. The patients were a 48-year-old female (Case 1), a 75-year-old female (Case 2) and an 82-year-old male (Case 3) with the chief complaint of asymptomatic gross hematuria. The histopathological diagnoses of the initial transurethral resection of the bladder tumor (TURBT) and second TURBT were urothelial carcinoma, pT1, HG and no malignancy in all three patients. Bladder tumors of all patients revealed sessile growth pattern and no presence of carcinoma in situ. Case 2 and 3 did not receive BCG vesical instillation after the second TURBT. Lymph node metastases appeared in Case 1 and Case 2 and lung metastasis appeared in Case 3. Tumor budding (TB) was positive in Case 1 and Case 2. Variant histology (VH) of nested morphology was detected in Case 1 and VH of inverted morphology in Case 2 and Case 3. Twenty-four months after the initial TURBT, Case 1 died due to cancer progression after cisplatin-based chemotherapy and pembrolizumab therapy. Thirty-three and 11 months after the initial TURBT, Case 2 and Case 3 were alive without cancer progression after cisplatin-based chemotherapy and/or pembrolizumab therapy, respectively. The two patients with T1 HG bladder cancer with TB had lymphatic metastasis and the patient without TB had hematogenous metastasis. Nested morphology is reportedly categorized as high-risk disease and inverted morphology as low-risk disease. TB might be correlated with lymphatic metastasis in T1 HG bladder cancer, and TB should be considered in the management of T1 HG bladder cancer. In the case of VH, the guidelines should be followed during the treatment decision of T1 HG bladder cancer.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 9","pages":"249-254"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Study of Retrograde Ureteroscopic Lithotripsy with Ureteral Access Sheath for Urinary Calculus After Ileal Conduit Construction]. [经尿道入路鞘逆行输尿管镜碎石术治疗回肠导管术后尿路结石的研究]。

Acta Urologica Japonica Pub Date : 2023-09-01 DOI: 10.14989/ActaUrolJap_69_9_239

Tetsuo Fukuda, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki

{"title":"[A Study of Retrograde Ureteroscopic Lithotripsy with Ureteral Access Sheath for Urinary Calculus After Ileal Conduit Construction].","authors":"Tetsuo Fukuda, Hironao Tajirika, Tatsuro Ishikawa, Junichi Matsuzaki","doi":"10.14989/ActaUrolJap_69_9_239","DOIUrl":"10.14989/ActaUrolJap_69_9_239","url":null,"abstract":"We retrospectively evaluated the safety and effectiveness of retrograde ureteroscopy via ileal conduit construction. Between January 2014 and December 2021, 5 patients (8 procedures) with ileal conduit construction received retrograde ureteroscopic lithotripsy with a 11/13 Fr ureteral access sheath. At postoperative 1 month, a plain computed tomography (CT) and kidney, ureter, and bladder X-ray (KUB) were performed to assess stone fragmentation and hydronephrosis. According to postoperative imaging, stone-free was defined as residual fragments of 4 mm or less on KUB and 2 mm or less on CT. The mean stone size was 11 mm (6-13 mm). The mean stone volume was 1. 51 ml (0.33-2.56 ml). The mean operative time was 91 min (60-133 min). SFR was 100% on KUB and 87.5% on CT. One procedure (12.5%) resulted in a postoperative fever greater than 38.5℃. There were no complications of grade III or higher according to the modified Clavien-Dindo classification. No exacerbation of hydronephrosis was observed on CT. Retrograde ureteroscopy with a ureteral access sheath was found to be effective for urolithiasis in patients with ileal conduit.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"69 9","pages":"239-242"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41162406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0