Acta Urologica Japonica最新文献

[Primary Malignant Melanoma Arising from the Anterior Urethra ; A Case Report]. 起源于前尿道的原发性恶性黑色素瘤；病例报告]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_203

Ryotaro Kawashima, Makito Miyake, Takuto Shimizu, Daiki Ichii, Kazuki Miyazaki, Mitsuru Tomizawa, Kenta Onishi, Syunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Kazumasa Torimoto, Tatsuo Yoneda, Nobumichi Tanaka, Kiyohide Fujimoto, Yoshihiro Tatsumi, Tomomi Fujii

引用次数: 0

[Primary Follicular Lymphoma of the Prostate Diagnosed after Robotic-Assisted Laparoscopic Radical Prostatectomy : A Case Report and Review of the Literature]. [机器人辅助腹腔镜根治性前列腺切除术后诊断的原发性前列腺滤泡性淋巴瘤：1例报告及文献回顾]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_197

Tateki Yoshino, Runa Matsubara, Yuya Ohata, Akira Shibahara, Ken Ando, Shinnosuke Fujikawa, Tomoyuki Sugitani, Taichi Nagami

{"title":"[Primary Follicular Lymphoma of the Prostate Diagnosed after Robotic-Assisted Laparoscopic Radical Prostatectomy : A Case Report and Review of the Literature].","authors":"Tateki Yoshino, Runa Matsubara, Yuya Ohata, Akira Shibahara, Ken Ando, Shinnosuke Fujikawa, Tomoyuki Sugitani, Taichi Nagami","doi":"10.14989/ActaUrolJap_71_6_197","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_6_197","url":null,"abstract":"Primary follicular lymphoma of the prostate is extremely rare, with this case representing only the 13th reported in the English literature. This report includes a review of the literature and details of a case in a 75-year-old male with concurrent primary follicular lymphoma and adenocarcinoma of the prostate. The patient was referred to our department due to prostate enlargement observed on CT and complaints of a decreased urinary stream. His PSA level was elevated at 8.9 ng/ml. MRI showed a PI-RADS category 4 lesion in the right peripheral zone of the prostate, with an estimated prostate volume of 60 ml. A transrectal prostate biopsy identified adenocarcinoma in two cores from the right base and one from the left apex, leading to a diagnosis of prostate cancer cT2aN0M0. Subsequently, the patient underwent robotic-assisted laparoscopic radical prostatectomy. Pathological findings confirmed adenocarcinoma in the right and left lobes (pT2a, pN0, EPE0, SV0, LVl1, RM0) and identified concurrent primary follicular lymphoma within the anterior fibromuscular stroma, which was positive for CD20, CD10 and Bcl-2. A complete clinical investigation, including an 18F-fluorodeoxyglucose positron emission tomography scan and bone marrow biopsy, revealed no involvement of other sites, and the patient was ultimately diagnosed with Ann Arbor stage IE lymphoma. No additional treatment was administered, and the patient has been followed up regularly. At six months postoperatively, there was no evidence of recurrence of either prostate cancer or lymphoma.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 6","pages":"197-202"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Superior Vena Cava Syndrome and Trousseau Syndrome in a Patient with Metastatic Urothelial Carcinoma Treated with Enfortumab Vedotin : A Case Report]. [上腔静脉综合征和Trousseau综合征在转移性尿路上皮癌患者中的应用：1例报告]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_191

Takuya Hida, Naoko Fujita, Takaya Murashima, Masato Fujii, Takahiro Nagai, Chie Onizuka, Koshiro Nishimoto, Atsuro Sawada, Shoichiro Mukai, Toshiyuki Kamoto

引用次数: 0

[Comprehensive Genomic Profiling Tests for Japanese Patients with Metastatic Castration-Resistant Prostate Cancer : A Single-Institution Experience]. [日本转移性去势抵抗性前列腺癌患者的综合基因组分析测试：单一机构的经验]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_171

Shiori Miyachi, Takeshi Sasaki, Momoko Kato, Shinichiro Higashi, Satoru Masui, Kouhei Nishikawa, Takumi Fujiwara, Takahito Kitajima, Yotaro Hashizume, Katsunori Uchida, Hiroshi Imai, Masatoshi Watanabe, Yoshinaga Okugawa, Takahiro Inoue

{"title":"[Comprehensive Genomic Profiling Tests for Japanese Patients with Metastatic Castration-Resistant Prostate Cancer : A Single-Institution Experience].","authors":"Shiori Miyachi, Takeshi Sasaki, Momoko Kato, Shinichiro Higashi, Satoru Masui, Kouhei Nishikawa, Takumi Fujiwara, Takahito Kitajima, Yotaro Hashizume, Katsunori Uchida, Hiroshi Imai, Masatoshi Watanabe, Yoshinaga Okugawa, Takahiro Inoue","doi":"10.14989/ActaUrolJap_71_6_171","DOIUrl":"10.14989/ActaUrolJap_71_6_171","url":null,"abstract":"Comprehensive genomic profiling for metastatic castration-resistant prostate cancer (mCRPC) is rapidly becoming widespread. This study sought to investigate the gene alteration profiles of Japanese patients with mCRPC. We retrospectively reviewed 80 consecutive mCRPC patients who underwent comprehensive genomic profiling tests at our institution between 2021 and 2022. All patients underwent next-generation sequencing (NGS) : FoundationOne® CDx (F1-CDx) or FoundationOne® Liquid CDx (F1L-CDx). F1LCDx was indicated for cases in which tissue specimens were older than 5 years or could not be analyzed using F1-CDx. The median patient age was 74 years. Thirty-five and 45 patients received F1-CDx and F1LCDx, respectively. At least one pathogenic variant was found in 35 (100%) who received F1-CDx and 43 (95%) who received F1L-CDx. In total, 11 and 1 patients had pathogenic variants of BRCA2 and BRCA1, respectively. Among them, 4 cases (33%) were found to be germline variants. TP53, CDK12, and PTEN were found in ＞ 20% of cases who received F1-CDx. DNMT3A, TP53, AR, and TET2 were found in ＞ 20% of cases who received F1L-CDx. The proportion of gene alteration subtypes of amplification and loss in F1L-CDx was less common than that in F1-CDx. Pathogenic variants were successfully detected in almost all F1-CDx and F1L-CDx cases in our mCRPC cohort. The total proportion of BRCA1/2 pathogenic variant patients was similar to those in previous reports.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 6","pages":"171-179"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Partial Nephrectomy for Juxtaglomerular Cell Tumor in the Renal Hilum]. [肾门肾小球旁细胞瘤部分切除1例]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_181

Sena I, Teppei Yamamoto, Kazuyoshi Iijima, Akio Miyamoto, Yukiko Kusama, Tomomi Haba, Takashi Hagimoto, Masashi Koshiba, Haruaki Kato

引用次数: 0

[A Case of Urothelial Carcinoma of Renal Pelvis Intraoperatively Diagnosed during Robot-Assisted Ureterocalicostomy]. [机器人辅助输尿管造口术中诊断肾盂尿路上皮癌1例]。

Acta Urologica Japonica Pub Date : 2025-06-01 DOI: 10.14989/ActaUrolJap_71_6_187

Yoshitaka Motoki, Toueki Yanagi, Shinpei Yoshioka, Masato Tomono, Motohiro Taguchi, Kimihiro Shimatani, Yusuke Yamada, Shuken Go, Akihiro Kanematsu, Shingo Yamamoto, Takashi Yamasaki, Seiichi Hirota

引用次数: 0

[Pyonephrosis Caused by Ureteral Stricture Due to Syphilitic Granuloma: A Case Report]. [梅毒肉芽肿致输尿管狭窄致脓肾1例]。

Acta Urologica Japonica Pub Date : 2025-05-01 DOI: 10.14989/ActaUrolJap_71_5_145

Seigo Machiya, Haruto Honda, Makoto Ishii, Hiromu Horitani, Sayaka Horii, Masao Kobayashi, Yutaka Ono, Shigeru Nakamori

引用次数: 0

[A Case of Ureteral Sciatic Hernia Treated by Laparoscopic Vesicoureterl Neoanastomosis]. [腹腔镜输尿管输尿管吻合术治疗输尿管坐骨疝1例]。

Acta Urologica Japonica Pub Date : 2025-05-01 DOI: 10.14989/ActaUrolJap_71_5_159

Kanji Nagahama, Toru Kanno, Kazuto Imai, Norihiko Masuda, Takahiro Maruyama, Haruki Imura, Keita Hanada, Takakazu Matsushita, Toshiya Akao

{"title":"[A Case of Ureteral Sciatic Hernia Treated by Laparoscopic Vesicoureterl Neoanastomosis].","authors":"Kanji Nagahama, Toru Kanno, Kazuto Imai, Norihiko Masuda, Takahiro Maruyama, Haruki Imura, Keita Hanada, Takakazu Matsushita, Toshiya Akao","doi":"10.14989/ActaUrolJap_71_5_159","DOIUrl":"10.14989/ActaUrolJap_71_5_159","url":null,"abstract":"Pelvic herniation of the ureter through anatomical musculoskeletal foramina stands out as one of the rarest causes of ureteric obstruction. The herniation of the ureter through the sciatic foramen presents as a particularly uncommon variant of this condition. A 62-year-old woman was referred to our hospital from a family practioner with symptoms of fever and septic shock. Subsequent computed tomography imaging revealed left hydroureteronephrosis without clear evidence of ureteral stones or ureteral tumors and that the lower part of the ureter was shifted to the outside of the cavum pelvis minor from the greater sciatic foramen. She was diagnosed with ureterosciatic hernia, and a left retrograde ureteral stent was indwelled. Her hemodynamic status improved and the ureteral stent was removed after ureteral migration became normal. However, three months later, left ureterosciatic hernia recurred. Therefore, we performed laparoscopic vesicoureteral neoanastomosis and native tissue repair of hernia by uterine appendages. The postoperative course was uneventful. We believe this is a durable repair although longer follow-up is needed to establish the longevity of our treatment modality.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 5","pages":"159-164"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pathophysiology of Semen Parameter Deterioration Associated with Varicocele --Evaluation of Total Antioxidant Capacity in Seminal Plasma and Serum-]. 精索静脉曲张相关精液参数恶化的病理生理学——精浆和血清总抗氧化能力的评估。

Acta Urologica Japonica Pub Date : 2025-05-01 DOI: 10.14989/ActaUrolJap_71_5_137

Masaki Kimura, Kazuki Takei, Kazuki Yanagida, Itsuki Yoshimura, Ichiro Takada, Tomoyuki Kaneko, Tohru Nakagawa

{"title":"[Pathophysiology of Semen Parameter Deterioration Associated with Varicocele --Evaluation of Total Antioxidant Capacity in Seminal Plasma and Serum-].","authors":"Masaki Kimura, Kazuki Takei, Kazuki Yanagida, Itsuki Yoshimura, Ichiro Takada, Tomoyuki Kaneko, Tohru Nakagawa","doi":"10.14989/ActaUrolJap_71_5_137","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_71_5_137","url":null,"abstract":"Varicocele is a frequent cause of male infertility. On the contrary, the majority of men who have varicocele show normal semen parameters. This study aimed to clarify the pathophysiology of abnormal semen findings associated with varicocele by evaluating the total antioxidant capacity in seminal plasma and serum. Sixty patients with clinical varicocele were included in this study. Of the 60 patients, 22 men had scrotal pain caused by varicocele with normal semen parameters, and 38 men had abnormal semen parameters as defined by the 2010 World Health Organization criteria. Before the investigation, semen samples were collected. Total antioxidant capacity in serum and seminal plasma was analyzed by colorimetric assay and the relationship between semen parameters and total antioxidant capacity was evaluated. Positive associations were found between antioxidant capacity in seminal plasma and concentration (r＝0.364, P＝0.004), motility (r＝0.254, P＝0.050), and total motile sperm count (r＝0.468, P＜0.001). In multivariate analysis, higher total motile sperm count showed a significant positive relationship with higher total antioxidant capacity in seminal plasma (P＝0.001). Our results indicated that the total antioxidant capacity of seminal plasma might affect varicocele-related male infertility.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"71 5","pages":"137-143"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Cut-to-the-light Incision for Ureteroileal Anastomotic Obstruction after Robot-Assisted Radical Cystectomy and Ileal Conduit]. [机器人辅助根治性膀胱切除术及回肠导管术后输尿管输尿管吻合口梗阻的切开式切口1例]。

Acta Urologica Japonica Pub Date : 2025-05-01 DOI: 10.14989/ActaUrolJap_71_5_155

Ryunosuke Murofushi, Daiki Ikarashi, Yasushi Nozaki, Moe Toyoshima, Ei Shiomi, Tomohiko Matsuura, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Jun Sugimura, Wataru Obara

引用次数: 0