Acta Urologica Japonica最新文献_第4页

[A Case of Urethral Foreign Body from 40 Years Ago with Scrotum Abscess and Urethroscrotal Fistula]. [40 年前尿道异物伴阴囊脓肿和尿道瘘病例]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_185

Yohei Kaizuka, Tetsuro Yoshimoto, Yutaka Doi, Motohiro Taguchi

引用次数: 0

[Resumption of Enfortumab Vedotin Supported by Diagnosis of a Late- Onset Immune-Related Adverse Event in Metastatic Urothelial Carcinoma : A Case Report]. [转移性尿路上皮癌晚期免疫相关不良事件诊断支持恢复使用恩福单抗维多汀：病例报告]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_161

Takeru Fujimoto, Yoshio Sugino, Kazuma Soya, Kana Kohashiguchi, Sachiko Higashino, Fumihiro Uwamori, Yusuke Takei, Hiroshi Iwamura

引用次数: 0

[A Case of Metastatic Prostate Cancer with Neuroendocrine Differentiation with Long-Term Survival after Multidisciplinary Therapy]. [神经内分泌分化转移性前列腺癌多学科治疗后长期生存病例]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_173

Koki Fujita, Minoru Kato, Yuki Kosugi, Yoshimasa Sekido, Nanami Matsui, Kazuki Masuda, Shoma Yamamoto, Taisuke Matsue, Keiko Iguchi, Nao Yukimatsu, Taiyo Otoshi, Takeshi Yamasaki, Katsuyuki Kuratsukuri, Kenichi Kohashi, Junji Uchida

{"title":"[A Case of Metastatic Prostate Cancer with Neuroendocrine Differentiation with Long-Term Survival after Multidisciplinary Therapy].","authors":"Koki Fujita, Minoru Kato, Yuki Kosugi, Yoshimasa Sekido, Nanami Matsui, Kazuki Masuda, Shoma Yamamoto, Taisuke Matsue, Keiko Iguchi, Nao Yukimatsu, Taiyo Otoshi, Takeshi Yamasaki, Katsuyuki Kuratsukuri, Kenichi Kohashi, Junji Uchida","doi":"10.14989/ActaUrolJap_70_6_173","DOIUrl":"10.14989/ActaUrolJap_70_6_173","url":null,"abstract":"A 74-year-old man visited the urology clinic with the chief complaint of urinary retention in December 2014. Serum level of initial prostate specific antigen (PSA) was 50 ng/ml and he was diagnosed with Gleason Score 4＋4 prostate adenocarcinoma with regional lymphadenopathy (cT3aN1M0). PSA level had declined after the treatment with combined androgen blockade. In November 2018, he was diagnosed with castration resistant prostate cancer (CRPC) as local progression was detected by computed tomography (CT) while PSA level did not increase. Since local symptoms worsened, resulting in repeated hematuria after the treatment with enzalutamide, palliative radiation therapy to the prostate (45 Gy) was performed. Five months later, follow-up CT showed multiple metastasis in bilateral lung and left testicle. Serum level of neuron-specific enolase (NSE) was 24.4 ng/ml without an elevated in serum PSA level. He received rebiopsy of the prostate, but no malignant findings were observed. Consequently, bilateral orchiectomy was performed for diagnosis of left testicular tumor. Pathological examination revealed metastasis of neuroendocrine prostate cancer (NEPC). Chemotherapy using cisplatin and irinotecan was administered after orchiectomy. Complete response of lung lesions was achieved and serum level of NSE decreased within normal range. No recurrence has been confirmed for 4 years after the completion of chemotherapy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 6","pages":"173-177"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Proliferative Cystitis Discovered as Protruding Lesion during Inspection of Secondary Infertility]. [在检查继发性不孕症时发现突出病变的增生性膀胱炎病例]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_167

Keita Okamoto, Kosuke Kojo, Masahiro Kurobe, Yoshimasa Nakazato, Hiromu Inai, Katsunori Uchida, Jun Miyazaki, Tatsuya Takayama

{"title":"[A Case of Proliferative Cystitis Discovered as Protruding Lesion during Inspection of Secondary Infertility].","authors":"Keita Okamoto, Kosuke Kojo, Masahiro Kurobe, Yoshimasa Nakazato, Hiromu Inai, Katsunori Uchida, Jun Miyazaki, Tatsuya Takayama","doi":"10.14989/ActaUrolJap_70_6_167","DOIUrl":"10.14989/ActaUrolJap_70_6_167","url":null,"abstract":"A 42-year-old man visited our hospital complaining of secondary infertility. An abdominal ultrasonography screening incidentally revealed a protruding lesion in the bladder. As the lesion extended from the prostatic urethra and bladder neck, there was a possibility of ejaculation dysfunction after resection of the lesion. Therefore, with the patient's informed consent, sperm cryopreservation was conducted for fertility preservation, and subsequently histological examination was performed by partial transurethral resection of bladder tumor. The pathological findings were proliferative cystitis including all three subtypes (glandularis, cystica, and papillary). Cyclooxygenase-2 immunostaining was positive in cytoplasm; weakly positive in cystic and papillary lesions, and strongly positive in glandular lesions. According to a literature review of massive proliferative cystitis, the patient was the 77th case in Japan. Novel postoperative immunological pharmacotherapies with cyclooxygenase-2 inhibitors have been introduced in recent years.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 6","pages":"167-171"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Xanthogranulomatous Pyelonephritis with Multiple Lymphadenopathy that was Difficult to Differentiate from Renal Tumor]. [黄疽性肾盂肾炎伴多发性淋巴结病难以与肾肿瘤鉴别的病例]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_149

Yuta Goto, Ei Shiomi, Mizuki Hisano, Shuhei Ishii, Takashi Ujiie, Yasuyuki Nakamura

{"title":"[A Case of Xanthogranulomatous Pyelonephritis with Multiple Lymphadenopathy that was Difficult to Differentiate from Renal Tumor].","authors":"Yuta Goto, Ei Shiomi, Mizuki Hisano, Shuhei Ishii, Takashi Ujiie, Yasuyuki Nakamura","doi":"10.14989/ActaUrolJap_70_6_149","DOIUrl":"10.14989/ActaUrolJap_70_6_149","url":null,"abstract":"A 74-year-old woman presented to our hospital with the main complaint of anorexia and weight loss for several months. Computed tomography (CT) revealed right urinary stone, hydronephrosis, multiple lymphadenopathy, and a mass in the right kidney. Considering these findings, she was suspected to have renal malignancy (kidney or renal pelvis cancer) with multiple lymph node metastases; therefore, nephrectomy was performed. Her pathological diagnosis was xanthogranulomatous pyelonephritis (XGPN). There was no postoperative renal function decline, and multiple lymphadenopathy also disappeared on CT 3 months after surgery. It was judged to be reactive swelling due to inflammation. XGPN is a pathological condition characterized by accumulation of mast cells and activated macrophages in the renal tissue; and, the renal tissue recognizes yellowish granulation growth because of repeating pyelonephritis due to urinary tract passing impairment. In some cases, it is difficult to differentiate XGPN from renal malignancy. Moreover, lymphadenopathy may be lymph node metastasis but may also present reactive enlargement due to the effect of inflammation, making it even more difficult to differentiate when accompanied by lymphadenopathy. We report this case in which it was difficult to differentiate XGPN from renal malignancy considering the scarcity of reports of XGPN accompanied by multiple lymphadenopathy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 6","pages":"149-153"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The Association of Docetaxel Side Effects and Introduction of Subsequent Cabazitaxel for Castration-Resistant Prostate Cancer : A Clinical Study]. [多西他赛副作用与后续卡巴他赛治疗阉割耐药前列腺癌的关联：一项临床研究]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_141

Yuma Kujime, Mototaka Sato, Takahiro Maekawa, Shun Umeda, Makoto Matsushita, Norihide Tei, Osamu Miyake

{"title":"[The Association of Docetaxel Side Effects and Introduction of Subsequent Cabazitaxel for Castration-Resistant Prostate Cancer : A Clinical Study].","authors":"Yuma Kujime, Mototaka Sato, Takahiro Maekawa, Shun Umeda, Makoto Matsushita, Norihide Tei, Osamu Miyake","doi":"10.14989/ActaUrolJap_70_6_141","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_6_141","url":null,"abstract":"The administration of cabazitaxel for patients with castration-resistant prostate cancer (CRPC) requires prior docetaxel therapy. Sequential chemotherapy may have to be discontinued due to docetaxelassociated side effects. This study investigated the relationship between treatment outcome of docetaxel and cabazitaxel and their associated side effects. We retrospectively analyzed 69 patients with CRPC who had been administered docetaxel withand without subsequent cabazitaxel at Toyonaka Municipal Hospital from October 2014 to June 2022. Twenty-eight patients (41%) discontinued docetaxel because of side effects, and the median number of docetaxel cycles at discontinuation was 2 (range : 1-11). Fourteen of these patients received no treatment following docetaxel. A comparison of the 28 patients who had discontinued docetaxel due to side effects with 41 patients who had not revealed a significant difference in the total numbers of chemotherapy cycles (2.5 vs 9 ; P＜0.001) and time to treatment failure (56 days vs 301 days ; P＝ 0.001), with a trend toward shorter overall survival from the start of docetaxel treatment (259 days vs 512 days ; P＝0.06). Multivariate analysis identified discontinuation of docetaxel due to side effects (OR＝0.07 ; P＜0.001) and lower hemoglobin (OR＝0.01 ; P＝0.001) as significant factors inhibiting the introduction of cabazitaxel. Reducing the side effects of docetaxel, including early drug switching, may allow more CRPC patients to be reached with cabazitaxel. Consequently, the resulting taxane-based chemotherapy may contribute to an additional survival advantage.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 6","pages":"141-147"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Granulocyte Colony-Stimulating Factor-Related Aortitis that Developed during the Treatment of Advanced Prostate Cancer with Neuroendocrine Differentiation]. [治疗神经内分泌分化的晚期前列腺癌期间出现的粒细胞集落刺激因子相关性大动脉炎病例]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_179

Tatsuya Hazama, Kohei Maruno, Toshifumi Takahashi, Yuya Yamada, Masakazu Nakashima, Kazuro Kikkawa, Masahiro Tamaki, Noriyuki Ito

{"title":"[A Case of Granulocyte Colony-Stimulating Factor-Related Aortitis that Developed during the Treatment of Advanced Prostate Cancer with Neuroendocrine Differentiation].","authors":"Tatsuya Hazama, Kohei Maruno, Toshifumi Takahashi, Yuya Yamada, Masakazu Nakashima, Kazuro Kikkawa, Masahiro Tamaki, Noriyuki Ito","doi":"10.14989/ActaUrolJap_70_6_179","DOIUrl":"10.14989/ActaUrolJap_70_6_179","url":null,"abstract":"An 81-year-old man with prostate cancer (cT3aN0M0), who had been undergoing hormonal therapy for 4 years and had maintained low prostate specific antigen levels, developed metastasized pelvic lymph nodes. A tissue biopsy revealed neuroendocrine differentiation of prostate cancer in the metastatic lymph nodes. Consequently, chemotherapy with carboplatin＋etoposide was initiated. During the first course, filgrastim was administered for 2 days due to a drop in his neutrophil count to 230/μl. During the second course, pegfilgrastim was administered as prophylaxis on day 4. However, on day 10 of the second course, he started to develop a fever and fatigue. Suspecting infection, antibiotics were administered, but failed to ameliorate his symptoms. On day 14, plain computed tomography revealed signs of aortic inflammation. Given the lack of improvement even after one week of antibiotic therapy, steroid treatment was initiated on the suspicion of granulocyte colony-stimulating factor (G-CSF) -induced aortitis, which rapidly improved his symptoms. Therefore, when encountering a case in which a fever remains unresponsive to antibiotics during chemotherapy with G-CSF agents, a differential diagnosis of aortic inflammation caused by G-CSF agents needs to be considered.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 6","pages":"179-183"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Repair of Vaginal Cuff Dehiscence after Laparoscopic Radical Cystectomy with Gracilis Myocutaneous Flap]. [用 Gracilis 肌皮瓣修复腹腔镜根治性膀胱切除术后阴道袖口开裂]。

Acta Urologica Japonica Pub Date : 2024-06-01 DOI: 10.14989/ActaUrolJap_70_6_155

Kanji Nagahama, Masaaki Ito, Kazuto Imai, Norihiko Masuda, Masahiro Takekawa, Tadashi Inoue, Takakazu Matsushita, Miyuki Ito, Toru Kanno, Toshiya Akao

引用次数: 0

[A Case of Metastatic Renal Cancer Responding to Sunitinib as the Eighth Line Therapy]. [一例对第八线疗法舒尼替尼有反应的转移性肾癌】。］

Acta Urologica Japonica Pub Date : 2024-05-01 DOI: 10.14989/ActaUrolJap_70_5_117

Mami Yamazaki, Kosuke Sakai, Kentaro Kiyozuka, Chiaki Nakamura, Masatoshi Kumagai, Masakatsu Ueda, Yusuke Shiraishi, Masaaki Imamura, Koji Yoshimura

引用次数: 0

[A Case of Lymphorrhea after Radical Cystectomy Treated by Ultrasound-Guided Inguinal Intranodal Lymphangiography]. [超声引导下腹股沟内淋巴管造影术治疗根治性膀胱切除术后淋巴结肿大一例]。

Acta Urologica Japonica Pub Date : 2024-05-01 DOI: 10.14989/ActaUrolJap_70_5_123

Taro Akai, Seiji Ueno, Atsushi Takeda, Satoru Tokuyama, Hiroshi Yamazaki

{"title":"[A Case of Lymphorrhea after Radical Cystectomy Treated by Ultrasound-Guided Inguinal Intranodal Lymphangiography].","authors":"Taro Akai, Seiji Ueno, Atsushi Takeda, Satoru Tokuyama, Hiroshi Yamazaki","doi":"10.14989/ActaUrolJap_70_5_123","DOIUrl":"10.14989/ActaUrolJap_70_5_123","url":null,"abstract":"A 76-year-old woman was diagnosed with invasive bladder cancer and underwent cystectomy, bilateral external iliac, internal iliac and obturator lymph node dissection, and bilateral cutaneous ureterostomy. Pathological findings showed no lymph node metastasis ; however, the patient had lower abdominal pain and fever from the 14th postoperative day, and computed tomography (CT) revealed fluid retention in the pelvis. Retrograde pyelography showed no leakage from the urinary tract, and a drain was placed after percutaneous puncture of the pelvic cavity. There was copious drainage fluid and its nature and composition suggested lymphorrhea. Ultrasound-guided intranodal lymphangiography revealed contrast material leakage from the bilateral lymph node dissection sites. After lymphangiography, drainage from the drain decreased. Despite the drainage being minimal yet persistent, sclerotherapy was performed, the drain was removed and the patient was discharged. After discharge, there was leakage from the site of urethral extraction, and CT revealed recurrent lymph leakage. The patient was readmitted, and a second lymphangiography was performed. The leakage from the site of urethral extraction gradually decreased, and the patient was discharged on the 59th postoperative day. CT after discharge confirmed that the lymphorrhea had shrunk in size, and there has been no recurrence since then. Lymphangiography is a promising treatment option for lymphorrhea after pelvic surgery.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 5","pages":"123-127"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0