Acta Urologica Japonica最新文献_第3页

[The Case of Solitary Adrenal Metastasis of Urothelial Carcinoma]. 尿路上皮癌单发肾上腺转移1例。

Acta Urologica Japonica Pub Date : 2025-01-01 DOI: 10.14989/ActaUrolJap_71_1_5

Shoma Yamamoto, Takeshi Yamasaki, Taisuke Matsue, Nao Yukimatsu, Taiyo Otoshi, Minoru Kato, Katsuyuki Kuratsukuri, Junji Uchida

引用次数: 0

[A Case of Mycoplasma genitalium Urethritis Refractory to Treatment]. 1例难治性生殖道支原体尿道炎。

Acta Urologica Japonica Pub Date : 2024-11-01 DOI: 10.14989/ActaUrolJap_70_11_387

Takanosuke Yoshikawa, Yoshitaka Itami, Kazuki Asada, Daiki Ichii, Kota Iida, Yukinari Hosokawa, Kiyohide Fujimoto

引用次数: 0

[Risk Factor of Cutaneous Symptoms Associated with Enfortumab Vedotin for Urothelial Carcinoma]. 尿路上皮癌与维多汀治疗相关皮肤症状的危险因素

Acta Urologica Japonica Pub Date : 2024-11-01 DOI: 10.14989/ActaUrolJap_70_11_361

Hiroyuki Honda, Tomohiro Matsuo, Shintaro Mori, Kyohei Araki, Kensuke Mitsunari, Kojiro Ohba, Yasushi Mochizuki, Ryoichi Imamura

{"title":"[Risk Factor of Cutaneous Symptoms Associated with Enfortumab Vedotin for Urothelial Carcinoma].","authors":"Hiroyuki Honda, Tomohiro Matsuo, Shintaro Mori, Kyohei Araki, Kensuke Mitsunari, Kojiro Ohba, Yasushi Mochizuki, Ryoichi Imamura","doi":"10.14989/ActaUrolJap_70_11_361","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_11_361","url":null,"abstract":"In 2021, Enfortumab Vedotin (EV) was approved for the treatment of locally advanced and metastatic urothelial carcinoma (UC) in Japan. Some patients require withdrawal or dose reduction due to cutaneous symptoms associated with EV treatment. Currently, the only reported associations of EV with cutaneous symptoms are pre-treatment performance status (PS) and body weight. However, no report has focused on the association between hematological factors and cutaneous symptoms. We retrospectively examined the occurrence of cutaneous symptoms and associated factors in patients who had been treated with EV for UC at Nagasaki University Hospital between February 2022 and June 2023. We evaluated the six patients with bladder cancer and three cases of upper urinary tract cancer. The median age was 73 [57-85] years. Seven patients had cutaneous reactions with EV treatment, and the median date of onset of the cutaneous symptoms was seven　[4 -28] days. PS was better inthe group with skinsymptoms compared with the group without (median : 1.0 vs 3.0), and in those with a higher incidence of eosinophilia or cutaneous symptoms on the previous regimen (71. 4% vs 0%). We suggested that the presence of eosinophilia or cutaneous symptoms at the time of pre-EV regimen administration may be a predictor of the appearance of cutaneous symptoms at the time of EV treatment. The limitation is that it is a single-center, small-case series, which does not allow for a rigorous statistical study.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 11","pages":"361-366"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Intestinal Metastasis of Testicular Choriocarcinoma Revealed Through Gastrointestinal Bleeding]. 【经胃肠道出血发现睾丸绒毛膜癌肠转移一例】。

Acta Urologica Japonica Pub Date : 2024-11-01 DOI: 10.14989/ActaUrolJap_70_11_379

Rei Ueno, Shunsuke Shinmei, Hayato Yoshioka, Tomoyo Murasawa, Yusuke Imura, Kousuke Sadahide, Yoshimasa Kurimura, Mitsuru Kajiwara

{"title":"[A Case of Intestinal Metastasis of Testicular Choriocarcinoma Revealed Through Gastrointestinal Bleeding].","authors":"Rei Ueno, Shunsuke Shinmei, Hayato Yoshioka, Tomoyo Murasawa, Yusuke Imura, Kousuke Sadahide, Yoshimasa Kurimura, Mitsuru Kajiwara","doi":"10.14989/ActaUrolJap_70_11_379","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_11_379","url":null,"abstract":"A 26-year-old male presented to a hospital with complaints of hemoptysis and right scrotal swelling. Computed tomography (CT) revealed right testicular swelling, multiple lung metastases, and small intestinal wall thickening. The patient's β-human chorionic gonadotropin, alpha-fetoprotein, lactate dehydrogenase, and hemoglobin levels were 103.3 ng/ml, 20.8 ng/ml, 300 U/l, and 11.3 g/dl, respectively. He underwent high orchidectomy after being diagnosed with a testicular tumor and multiple lung metastases. Histopathological examination revealed a mixed germ cell tumor (60% choriocarcinoma, 20% seminoma, 10% embryonal carcinoma, 10% mature teratoma, and 1% yolk sac tumor). As the patient exhibited active gastrointestinal hemorrhage requiring frequent blood transfusions, gastrointestinal endoscopy was performed to investigate its cause. When upper and lower gastrointestinal endoscopies revealed no bleeding, the patient was referred to our hospital for further examination and treatment. A small bowel endoscopy revealed a hemorrhagic jejunal mass. Because endoscopic hemostasis was challenging, we partially resected the small intestine. Pathological findings in the resected lesion were consistent with small intestinal metastasis of the testicular tumor. The tumor markers turned negative after four cycles of BEP and four cycles of TIP chemotherapy. He then underwent resection of the remaining lung tumor, and no residual tumor or recurrence was detected one year later.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 11","pages":"379-386"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical Study of Lymph Node Dissection in Robot-Assisted Radical Prostatectomy for High-Risk Prostate Cancer]. 机器人辅助前列腺根治术治疗高危前列腺癌淋巴结清扫的临床研究

Acta Urologica Japonica Pub Date : 2024-11-01 DOI: 10.14989/ActaUrolJap_70_11_367

Shotaro Hatano, Takayuki Goto, Jin Kono, Takayuki Sumiyoshi, Kimihiko Masui, Takuma Sato, Takeshi Sano, Atsuro Sawada, Shusuke Akamatsu, Takahiro Inoue, Osamu Ogawa, Takashi Kobayashi

{"title":"[Clinical Study of Lymph Node Dissection in Robot-Assisted Radical Prostatectomy for High-Risk Prostate Cancer].","authors":"Shotaro Hatano, Takayuki Goto, Jin Kono, Takayuki Sumiyoshi, Kimihiko Masui, Takuma Sato, Takeshi Sano, Atsuro Sawada, Shusuke Akamatsu, Takahiro Inoue, Osamu Ogawa, Takashi Kobayashi","doi":"10.14989/ActaUrolJap_70_11_367","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_11_367","url":null,"abstract":"We retrospectively analyzed the regions and perioperative outcomes associated with lymph node dissection in patients with prostate cancer. Of 543 patients who underwent robot-assisted radical prostatectomy for prostate cancer with or without lymph node dissection according to the modified D'Amico criteria, 333 (61.3%), 128 (23.6%), and 82 (15.1%) were classified into the non-dissection, limited dissection, and extended dissection groups, respectively. Lymph node metastasis was identified in eight patients : one in the limited dissection group and seven in the extended dissection group. Notably, all eight biopsies showed Gleason scores of 4＋4 or higher, and the initial prostate-specific antigen (PSA) concentration was ≥10 ng/ml in seven of these patients. Lymph node metastasis was detected in areas other than the obturator lymph nodes in five patients (62.5%). Although there was no significant difference in the rate of Clavien- Dindo grade ≥II complications among the three groups, six patients (7.3%) in the extended dissection group developed infectious lymphoceles. In the extended dissection group, the PSA progression-free survival (PSA-PFS) was significantly shorter in patients with than in those without lymph node metastasis (p＜0.001). Because lymph node metastases were rare in the limited dissection group in our cohort of patients with a high risk of localized prostate cancer, achieving a diagnosis seems difficult with limited dissection. By contrast, in the extended dissection group, the PSA-PFS prognosis was significantly worse in lymph node-positive cases. Therefore, considering the high complication risk of lymphoceles, extended dissection should be performed in patients with a high likelihood of lymph node metastasis.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 11","pages":"367-372"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical Outcomes of Transurethral Water Vapor Energy Therapy with Rezumᵀᴹ System]. 经尿道水蒸汽能量疗法与Rezum - <e:1>系统的临床疗效观察

Acta Urologica Japonica Pub Date : 2024-11-01 DOI: 10.14989/ActaUrolJap_70_11_373

Yoshiko Sugita, Toshiya Shitara, Hideharu Bessho, Haruko Takada, Satoru Bando, Hiroyuki Otani, Tetsuo Fujita, Masatsugu Iwamura

{"title":"[Clinical Outcomes of Transurethral Water Vapor Energy Therapy with Rezumᵀᴹ System].","authors":"Yoshiko Sugita, Toshiya Shitara, Hideharu Bessho, Haruko Takada, Satoru Bando, Hiroyuki Otani, Tetsuo Fujita, Masatsugu Iwamura","doi":"10.14989/ActaUrolJap_70_11_373","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_11_373","url":null,"abstract":"We carefully reviewed and evaluated the efficacy of transurethral water vapor energy therapy (WAVE) with Rezumᵀᴹ system for treatment of benign prostatic hyperplasia. Between April and September 2023, 41 patients received WAVE under local anesthesia as day surgery at the outpatient department in our institution. The mean age as of operation was 78.7 years, and mean estimated prostatic volume was 42.3 ml. The median total operative time was 2 minutes, median puncture number of time was 3 times, and median duration of urethral catheter day was 7 days. The International Prostate Symptom Score (IPSS), quality of life (QOL) index, and maximum flow rate (Qmax) were assessed preoperatively and at 1 and 3 months postoperatively. In this evaluation, IPSS and QOL index improved significantly at 1 month postoperatively (IPSS : p＝0.023, QOL index : p＜0.001). Although Qmax was not significantly different between preoperative and 1 month postoperatively (p＝0. 167), a significant difference was shown at 3 months postoperatively (p＝0.006). Objective test findings such as Qmax required more than 1 month to improve. Subjective symptoms such as IPSS and QOL index improved in an early postoperative period. In conclusion, WAVE is an effective procedure for the treatment of benign prostatic hyperplasia.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 11","pages":"373-377"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Retroperitoneal Primary Undifferentiated Pleomorphic Sarcoma with a Rapid Course]. 腹膜后原发性未分化多形性肉瘤1例。

Acta Urologica Japonica Pub Date : 2024-10-01 DOI: 10.14989/ActaUrolJap_70_10_331

Kentaro Kiyozuka, Ryosuke Suzuki, Kosuke Sakai, Naoki Kohei, Akinori Nozawa

{"title":"[A Case of Retroperitoneal Primary Undifferentiated Pleomorphic Sarcoma with a Rapid Course].","authors":"Kentaro Kiyozuka, Ryosuke Suzuki, Kosuke Sakai, Naoki Kohei, Akinori Nozawa","doi":"10.14989/ActaUrolJap_70_10_331","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_10_331","url":null,"abstract":"A 50-year-old woman presented to our hospital in May2021 with a fever of approximately39 °C and abdominal pain. A contrast-enhanced computed tomography (CT) scan revealed an 88 mm right renal tumor. Two weeks later, a follow-up CT scan demonstrated rapid tumor growth, with the major axis measuring 100 mm. During this interval, her abdominal pain worsened, and she developed lower leg edema. A contrast-enhanced CT scan conducted 5 days before the scheduled surgery, four weeks after initial presentation, showed further tumor progression, with a diameter of 155 mm. The tumor, which had infiltrated the ascending colon, duodenum, liver, gallbladder, and inferior vena cava (IVC), was surgically removed along with the right kidney. Due to its complexity, the planned wide excision was deemed infeasible. Therefore, a tumor resection was performed macroscopically. Histopathological examination confirmed the diagnosis of undifferentiated pleomorphic sarcoma (UPS). Subsequently, the patient experienced a postoperative tumor recurrence. Although the patient received doxorubicin chemotherapy, she passed away5 weeks after the operation. This case highlights the critical importance of prompt surgical excision with adequate tumor margins in the management of UPS.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 10","pages":"331-334"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Secondary Extramammary Paget's Disease Developed at 11 Years after Cystectomy]. [膀胱切除术后11年继发乳腺外佩吉特病1例]。

Acta Urologica Japonica Pub Date : 2024-10-01 DOI: 10.14989/ActaUrolJap_70_10_335

Yuki Nishimura, Yuta Oki, Daichi Nonomura, Kyosuke Matsuzaki, Kensaku Nishimura

{"title":"[A Case of Secondary Extramammary Paget's Disease Developed at 11 Years after Cystectomy].","authors":"Yuki Nishimura, Yuta Oki, Daichi Nonomura, Kyosuke Matsuzaki, Kensaku Nishimura","doi":"10.14989/ActaUrolJap_70_10_335","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_10_335","url":null,"abstract":"An 82-year-old woman previously underwent cystectomy and ureterocutaneous ureteral fistula for bacillus calmette guerin-resistant bladder cancer at the age of 70 years old in February 2012. Pathological examination revealed a pTisN0. In October 2020, the patient experienced vulvar itching and pain, which prompted her to consult a gynecologist. Vulvovaginitis was diagnosed, and the patient was observed. However, in June 2023, the vulvar itching persisted, prompting a biopsy for refractory erosions of the vulva. Paget cells were identified in the epidermis, and immunostaining (CK7 (＋), CK20 (＋), p63 (＋), GATA3 (＋), and GCDFP15 (-)) was used to diagnose secondary extramammary Paget's disease due to urothelial carcinoma. Magnetic resonance imaging revealed a 25 mm mass in the pelvic floor, and a biopsy showed the same immunostaining pattern as the skin lesion. Consequently, a diagnosis of local recurrence 11 years after cystectomy and associated secondary extramammary Paget's disease was established. Owing to the evidence of invasion of the mass into the levator ani muscle, she underwent laparoscopic rectal resection plus combined resection of the tumor, perineum, and levator ani muscle in October. Currently, she is 3 months postoperatively without evidence of recurrence.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 10","pages":"335-341"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Assessment of Risk Factors for Reinsertion of Indwelling Urinary Catheters Despite Intervention for Voiding Disturbances by the Urination Care Team]. [评估留置导尿管再次插入的危险因素，尽管排尿护理小组干预排尿障碍]。

Acta Urologica Japonica Pub Date : 2024-10-01 DOI: 10.14989/ActaUrolJap_70_10_323

Masayuki Kurokawa, Fumiko Okada, Kosuke Ogawa, Yoshiyuki Okada, Mitsue Ito, Manami Shimizu, Takahiro Nonaka, Kazutoshi Okubo

{"title":"[Assessment of Risk Factors for Reinsertion of Indwelling Urinary Catheters Despite Intervention for Voiding Disturbances by the Urination Care Team].","authors":"Masayuki Kurokawa, Fumiko Okada, Kosuke Ogawa, Yoshiyuki Okada, Mitsue Ito, Manami Shimizu, Takahiro Nonaka, Kazutoshi Okubo","doi":"10.14989/ActaUrolJap_70_10_323","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_10_323","url":null,"abstract":"A urination care team comprising professionals from various fields was developed. This team intervened during hospitalization of patients who were either expected to have voiding disturbances following the removal of indwelling urinary catheters or develop voiding disturbances following catheter removal during hospitalization. The team aims to remove unnecessary indwelling urinary catheters and promote patient independence during urination. However, if patients do not achieve spontaneous micturition or clean intermittent self-catheterization (CISC) during their hospital stay, an indwelling urinary catheter is reinserted. In this study, risk factors for indwelling urinary catheter reinsertion were retrospectively analyzed during hospitalization. In total, 98 patients from January 1, 2018, to December 31, 2020, were examined at Kyoto Katsura Hospital, where the urination care team intervened due to voiding disturbances with residual urine of ≥100 ml. At discharge, 46 (46%) patients were able to urinate independently, 9 (9%) were voiding through a diaper, 14 (14%) practiced CISC, and 29 (30%) had indwelling urinary catheters. Multivariate analysis revealed that age ≥75 years (p＝0.03), a cognitive functional independence measure (FIM) score of ≤25 on admission (p＜0.01), and residual urine of ≥300 ml at intervention (p＝0.03) were independent risk factors affecting the indwelling urinary catheter reinsertion. The indwelling urinary catheter non-reinsertion and reinsertion groups demonstrated significant improvement in the FIM total and motor scores between admission and discharge ; however, the FIM cognitive score did not show any statistically significant difference.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 10","pages":"323-330"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Study of the Prognosis of Prostate Cancer Patients Over 80 Years of Age]. 80岁以上前列腺癌患者预后的研究

Acta Urologica Japonica Pub Date : 2024-10-01 DOI: 10.14989/ActaUrolJap_70_10_309

Kodai Hattahara, Yuki Hashimoto, Masayuki Uegaki, Koji Nishizawa, Toru Yoshida

{"title":"[A Study of the Prognosis of Prostate Cancer Patients Over 80 Years of Age].","authors":"Kodai Hattahara, Yuki Hashimoto, Masayuki Uegaki, Koji Nishizawa, Toru Yoshida","doi":"10.14989/ActaUrolJap_70_10_309","DOIUrl":"https://doi.org/10.14989/ActaUrolJap_70_10_309","url":null,"abstract":"With the ageing of the population in Japan, an increasing number of elderly prostate cancer patients will require treatment. However, the elderly often have comorbidities, which can make treatment decisions for prostate cancer patients difficult. Therefore, we investigated prostate cancer deaths and risk factors among patients aged 80 years or older at diagnosis of prostate cancer at our hospital. Of 532 prostate cancer cases diagnosed and treated at our hospital between January2011 and December 2018, 90 cases were included. The median observation period was 54 months and 13 (14.4%) patients died of prostate cancer. The overall 5-year cancer-specific survival rate was 86.7%, with M1 (47.1%) and GS≥9 (71.9%) as significant risk factors on multivariate analysis. Patients with metastatic prostate cancer, even those older than 80 years, should be cautiously started on treatment after explaining to the patient and family that the chance of prostate cancer death is not low. Even in patients with localized prostate cancer, four out of 45 (8.9%) high-risk prostate cancer patients died of prostate cancer, suggesting that curative treatment is an option, depending on their life expectancy.","PeriodicalId":39291,"journal":{"name":"Acta Urologica Japonica","volume":"70 10","pages":"309-315"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0