Muhammad Asif, Wahab J Khan, Awais Aslam, Hammad S Chaudhry, Daud Shehzad
{"title":"Managing Congestive Heart Failure at Home by Transitioning From Intravenous Furosemide to a Subcutaneous Route.","authors":"Muhammad Asif, Wahab J Khan, Awais Aslam, Hammad S Chaudhry, Daud Shehzad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Heart failure is one of the leading chronic conditions affecting millions of individuals in the U.S. and across the globe. Congestive heart failure (CHF) is one of the leading diagnoses resulting in acute hospitalizations for administration of intravenous (IV) diuretics, hence putting significant direct economic costs from in-hospital treatment and indirect due to loss of work being hospitalized. With the ever-increasing strain on hospital beds and staffing from a variety of acute illnesses, there has been an urge to treat patients in outpatient settings as much as possible, providing highquality care and using hospitalization only as a last resort. Recently, there have been successful attempts to treat patients with subcutaneous furosemide and achieve results similar to conventional IV diuresis. In this article, we highlight some of the details and outcomes of these studies and summarize the important considerations about the utility of subcutaneous furosemide in treating CHF exacerbation.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 3","pages":"127-131"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Pembrolizumab Induced Pericardial Tamponade in a 77-Year-Old.","authors":"Muhammad Hasan, Melanie LaVoie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a rare case of pericardial tamponade in a 77-year-old male with metastatic squamous cell carcinoma (SCC) of the head and neck receiving pembrolizumab. Despite pembrolizumab revolutionizing cancer treatment, it can engender a spectrum of immune-related adverse events. Our patient presented with acute dyspnea and chest pain two weeks post pembrolizumab infusion and was diagnosed with pericardial tamponade requiring an emergent pericardial window. Our case highlights the importance of recognizing and managing this life threatening cardiac event that occurs in up to 0.4% of patients on pembrolizumab or other immune checkpoint inhibitors (ICI).</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 3","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gonococcal Arthritis-Dermatitis Syndrome.","authors":"Peter Pc Lim","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 3","pages":"137"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mystifying Masquerade: Renal Cell Carcinoma Associated Arteriovenous Fistula Presenting as High-Output Heart Failure - A Case Study.","authors":"Jaswanth Rao Jasti, Thabuna Sivaprakasam, Randall Lamfers, Orvar Jonsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We detail an uncommon presentation of high-output heart failure (HOHF) triggered by an arteriovenous fistula (AVF) associated with renal cell carcinoma (RCC) in a middle-aged woman with widespread anasarca. The rarity of HOHF linked to malignancies posed significant diagnostic challenges. This case emphasizes the intricate and thorough diagnostic process required to elucidate the connection between RCC and HOHF. The utilization of advanced abdominal imaging, right heart catheterization, and precise blood gas analysis from both the inferior vena cava and renal vein was pivotal in establishing the diagnosis. This comprehensive diagnostic regimen was crucial in identifying the RCC-associated AVF as the causative factor for HOHF, highlighting the importance of a detailed investigative approach in cases of unusual cardiac presentations associated with malignancy.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"65-67"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nilotinib Induced Large Pericardial Effusion in a Patient Being Treated for Chronic Myeloid Leukemia.","authors":"Muhammad Hasan, Melanie LaVoie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nilotinib, a second generation tyrosine kinase inhibitor, has remarkably improved outcomes in patients with newly diagnosed Philadelphia chromosome positive (Ph+) chronic myelogenous leukemia by targeting BCR-ABL1 fusion protein. Despite the safety and efficacy of these agents, adverse side effects can occur due to unintended inhibition of off-target kinases. While the clinical ramifications of serosal inflammation - including pleural and pericardial effusions - have been a common occurrence in patients on older tyrosine kinase inhibitors (TKI), the effect of nilotinib causing pericardial effusion is rare. This case report highlights a rare occurrence of pericardial effusion while being treated with nilotinib for chronic myeloid leukemia.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"61-62"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helean Barwari, Matthew Billion, Andrew Guymon, Jared Hueser, Alexandra Kracht, Tayler Modlin, Emily Petersen, Anthony Restaino, John Richter, Nathan Stadem, Jake Vaca, Michelle Schimelpfenig
{"title":"Observing Siblings of Children with Complex Medical Needs.","authors":"Helean Barwari, Matthew Billion, Andrew Guymon, Jared Hueser, Alexandra Kracht, Tayler Modlin, Emily Petersen, Anthony Restaino, John Richter, Nathan Stadem, Jake Vaca, Michelle Schimelpfenig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study examined the behaviors of siblings of child(ren) with complex medical needs (CCMN). Previous research indicates that these siblings may develop resilience and empathy, but also face risks like depression and poor social skills. To gain further insights, we completed surveys after observing family interactions. We reviewed 96 surveys, finding that siblings provided physical care 42.6% of the time and emotional care 32.5% of the time. Reactive outbursts were seen in 22.1% of cases, and 55.2% of siblings spent time alone, apart from their CCMN sibling. One-on-one time with parents was noted in 50% of observations, and siblings joined activities in 91.7% of cases. The siblings were mostly happy (73.7%), with some neutral (22.1%) and sad (4.2%). Conflicts occurred in 53.1% of cases, usually with mothers addressing the conflict. These findings show that siblings of CCMN often take on significant caregiving roles, which can affect their emotional and social development. Although the study was set in a vacation environment, it highlights the importance of recognizing the unique challenges these siblings face. More research is needed to understand how age and the severity of the medical condition influence sibling experiences.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"68-74"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dawood Shehzad, Helean S Barwari, Mustafa Shehzad, Garcia Alfredo
{"title":"Cytomegalovirus Ventriculoencephaltis Post-Temozolomide Use For Glioblastoma Multiforme.","authors":"Dawood Shehzad, Helean S Barwari, Mustafa Shehzad, Garcia Alfredo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a case of a male in his 60s with a past medical history of glioblastoma status post chemoradiotherapy and surgical resection. He had completed neoadjuvant temozolomide and was 26 days post-chemotherapy on presentation. He presented with fever, weakness, and confusion. Further evaluation revealed cytomegalovirus (CMV) ventriculoencephaltis. He was started on valganciclovir, but his hospital course was complicated by a pulmonary embolism. Repeat imaging showed tumor progression, and he was a poor surgical candidate. This case highlights the complexities of managing patients with opportunistic infections post-chemotherapy. It adds to the growing literature of disseminated, invasive, and often lethal CMV infections in non-HIV patients post-use of temozolomide. We urge the need for vigilant monitoring and consideration of prophylactic measures in individuals deemed at risk for invasive CMV.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Images in Medicine: Hydroa vacciniforme: An Unusual Dermatologic Complication of Epstein-Barr Virus Infection.","authors":"Peter Pc Lim","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"87"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conflicting Evidence Regarding Midodrine Use to Improve the Tolerability of Diuretics and Outcomes in Patients with Cirrhotic Ascites.","authors":"Dawood Shehzad, Mustafa Shehzad, Dawlat Khan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 2","pages":"53-56"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of Electrosurgical Unit Terminology and Applications in Orthopaedic Surgery.","authors":"Alexander J Bergeson, Nathan W Skelley","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 1","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}