South Dakota medicine : the journal of the South Dakota State Medical Association最新文献

{"title":"Expanding the Genetic Etiology of Multiple Morphological Abnormalities of the Sperm Flagella: A Case Report of Two Novel DNAH1 Variants.","authors":"Emily Anderson, Megan Bell, Katherine Hornberger, Jason Flanagan, Kayleigh Avello, Fang Xu, Steffen Christensen, Ellen Johnson","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The following case report details the genetic evaluation and treatment of a 30-year-old male with a history of asthenoteratospermia and notable abnormalities of the sperm flagella.</p><p><strong>Methods: </strong>Genetic evaluation was performed via a multi-gene panel of genes associated with primary ciliary dyskinesia and multiple morphological abnormalities of the sperm flagella (MMAF) prior to the couple's in vitro fertilization (IVF) cycle.</p><p><strong>Results: </strong>Genetic evaluation was performed via a multi-gene panel of genes associated with primary ciliary dyskinesia and multiple morphological abnormalities of the sperm flagella (MMAF) prior to the couple's in vitro fertilization (IVF) cycle.</p><p><strong>Conclusions: </strong>The two novel DNAH1 variants add to the growing body of evidence of the relationship between DNAH1 and multiple morphological abnormalities of the sperm flagella. DNAH1 variants and abnormal sperm morphology appear to negatively impact embryo development. Genetic counseling can aid in genetic testing and counseling related to male infertility.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"540-544"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tularemia in a Psoriasis Patient on Biologic Therapy After Relocation to Western South Dakota.","authors":"Alek Keegan, Luke Fritsch, James Engelbrecht","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Francisella tularensis is an aerobic, gram negative coccobacillus bacterium that causes tularemia. F. tularensis spreads primarily through ticks, biting flies, droplet inhalation, contaminated mud or water, or infected animal bites, and it can survive in animal carcasses with the most common mode of transmission occurring via inoculation into the skin and inhalation/ingestion. Individuals on biologics or immunosuppressive medications are at an increased risk for infections such as tularemia, particularly when moving geographically to regions where it is endemic.</p><p><strong>Case description: </strong>We describe a case of tularemia presenting in a South Dakota resident. The patient, who was on long term adalimumab, presented with persistent fever, chills, fatigue, night sweats and anorexia for 6 days. The patient had recently moved from eastern South Dakota to western South Dakota onto a farm that is mostly pasture land. Chest imaging showed bilateral nodular densities, and lymph node biopsy was diagnostic for F. tularensis. A diagnosis of tularemia was made based on her biopsy results and exposure to rabbit carcasses while mowing grass on her ranch. She was started on antibiotic therapy, and her symptoms and imaging improved. She followed up with internal medicine and infectious disease clinic, and her symptoms resolved and imaging cleared with transition to ciprofloxacin in the outpatient setting; additionally, she continues to do well with no evidence of recurrence of active infection.</p><p><strong>Conclusions: </strong>It is important that clinicians recognize the geographical dimension in infectious disease risk for immunosuppressed individuals. The patient's experience with tularemia following her relocation from eastern to western South Dakota highlights how geographic transitions can introduce new infectious exposures and risks. For patients on immunosuppressive therapies, healthcare providers must consider potential infections endemic to the new region and adopt proactive management strategies. Early recognition, targeted therapy, and adjustments in immunosuppression are critical in managing such cases effectively. This case illustrates the importance of detailed travel histories, patient education, and coordination between specialists to ensure comprehensive care and optimal outcomes for immunocompromised patients in new environments.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"550-555"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do We Need a Fluid Bolus? The Necessary Refinement of Pediatric Propofol Sedation - a Quality Improvement Project.","authors":"Andrew L Guymon, Madigan M Moore, Laura E Nelson, Mir Ali","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Propofol is commonly used for pediatric MRIs to minimize patient movement. At our institution, intensivists typically administer a prophylactic 20 ml/kg saline bolus to maintain blood pressure (BP) during propofol sedation. This quality improvement project assessed whether a 10 ml/kg and a completely eliminated saline bolus are as effective as the standard 20 ml/kg bolus in completing pediatric propofol sedation and maintaining Mean Arterial Pressure (MAP).</p><p><strong>Methods: </strong>We reviewed pediatric propofol sedations over an 18 month period in which pediatric intensivists administered the standard 20 ml/kg saline bolus, a reduced 10 ml/kg bolus, and no saline bolus. Successful sedation meant completing the MRI without complications.</p><p><strong>Results: </strong>172 patients aged 19 months to 16 years were assessed. The percentage of successful sedations with a 20 ml/kg bolus, 10 ml/kg bolus, and no saline bolus was 92%, 100%, and 91%, respectively. There was a statistically significant higher average MAP in the 0 ml/kg group than in the 10 and 20 ml/kg cohorts (p = 0.002). No patients required an additional bolus to maintain blood pressure.</p><p><strong>Conclusions: </strong>The preservation of hemodynamic stability without a saline bolus supports the literature that the saline bolus can be safely reduced during pediatric propofol sedation for MRI.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"557-560"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Access to Palliative Care through Education and Training.","authors":"Amanda Kay Sedlacek, Michelle Gierach, Michele Snyders, Sarah Mollman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The population is aging, especially in rural areas where people experience higher rates of mortality and chronic illness as well as greater distances to care, including specialty care. Since there is a lack of access to specialty palliative care, all clinicians must be trained to provide the fundamentals of palliative care to improve quality of life and limit suffering. Numerous options are available for clinicians to be trained in palliative care. A long-standing palliative care training option in South Dakota is the Interdisciplinary Palliative Care (IPC) Seminar which trains students from multiple disciplines in the foundation of palliative care. It has demonstrated significant student learning outcomes for 22 years. The IPC Seminar transitioned to virtual delivery in 2020 allowing additional students to participate across the state. It is currently hosted within the University of South Dakota Interprofessional Health Education Center which fostered additional disciplines to participate. As the need for palliative care grows in our state, so too, does the need for palliative care education whether it is acquired through national organizations or local education providers.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"546-548"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dr. TikTok: The Viral Social Media App Acting as the Newest Self-Diagnosis Platform.","authors":"Cole D Tessendorf","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"531"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Cardiac Imaging Modalities: A Brief Review for the Primary Care Physician.","authors":"Muhammad Hasan, Ninad Nadkarni, Naveen Rajpurohit","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Advanced cardiac imaging modalities have revolutionized the field of cardiovascular medicine, offering invaluable tools for both diagnosis and the management of a wide spectrum of cardiovascular diseases. These imaging methods, including echocardiography, cardiac computed tomography (CT), computed tomography angiography (CTA), cardiac magnetic resonance imaging (MRI), nuclear imaging, and fluoroscopy, offer various approaches to evaluate both the structure and function of the heart. This article provides an overview of imaging modalities for primary care physicians, highlighting their types, advantages, limitations and clinical uses.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"562-570"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey of Employed Orthopedic Surgeons Ability to Estimate Operating Room Device Costs.","authors":"Michaela Derby, Edward Floyd, David Sturdevant, Hunter O'Connor, Nathan Skelley","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Orthopaedic devices represent a large amount of the overall cost incurred in the operating room. It is unknown if employed sports medicine surgeons are aware of the true prices of these devices. The purpose of this study was to assess sports medicine orthopaedic surgeons' knowledge of implant and device costs, as well of commonly used items in their operating rooms.</p><p><strong>Methods: </strong>REDCap surveys were distributed to 18 orthopaedic surgeons who perform arthroscopic and sports medicine procedures. All surgeons are employed at a healthcare system spanning four different states. Surgeons estimated the cost of 26 items used in the operating room. A surgeon reported cost within 10% of the actual price was established as having awareness of that item's cost.</p><p><strong>Results and conclusions: </strong>Response rate was 89% (16/18). Twenty-five percent (n = 4) of surgeons were within 10% of the actual cost of only one item (Swivelock 4.75mm). Forty-three percent (n = 7) were within 20% of the actual cost of one item (Achilles Allograft). Those who perceived they had the poorest insight into device costs were found to have the greatest difference between estimated and actual cost. Surgeons in our study were not aware of the cost of commonly used items and implants in the operating room. Surgeons with greater insight into this topic can contribute toward a more value-based delivery of care. These findings support engaging employed physicians with initiatives to increase their awareness of the actual cost of the care they deliver, benefiting the whole healthcare system.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 12","pages":"534-539"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carpal Tunnel, Trigger Finger, and Spinal Stenosis: The Rest of the Story.","authors":"Joseph Rath, Victoria Durkin, Robert E Van Demark","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Amyloidosis is a deadly systemic disease in which misfolded proteins accumulate in human tissue eventually leading to morbid dysfunction in multiple organ systems. The prognosis of untreated amyloidosis is poor. Orthopedic manifestations of amyloidosis include carpal tunnel syndrome (CTS), trigger digit, distal biceps tendon rupture, rotator cuff disease, and lumbar spinal stenosis. These orthopedic conditions are early red flags for systemic amyloidosis. CTS is often the earliest manifestation and can precede the disease by over four years. With the advent of medications that can slow the progression of amyloidosis, particularly in the early stages of the disease, it is imperative to diagnose amyloidosis early on. Both primary care physicians and orthopedic surgeons can recognize the various orthopedic conditions associated with amyloidosis and play a vital role in early disease detection. Awareness of the musculoskeletal presentation of systemic amyloidosis can lead to earlier detection and treatment that can delay the progression of the disease.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 11","pages":"516-525"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From GRIT to Determination.","authors":"Jason J Kemnitz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 11","pages":"483"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report: Rosuvastatin Induced Rhabdomyolysis in an 80-Year-Old Female.","authors":"Muhammad Hasan, Mohammad Ahmed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rosuvastatin, a commonly prescribed lipid-lowering medication for primary and secondary prevention of cardiovascular disease, is generally considered safe with associated mortality benefits. Despite its overall safety profile, the drug is not without side effects. Statin-induced myopathy, a known complication, can manifest in 10-25% of cases, while more uncommon complications such as rhabdomyolysis occur in less than 0.1% of treated patients. In this case report, we present an 80-year-old female presenting with rhabdomyolysis attributable to rosuvastatin.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"77 11","pages":"501-502"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}