{"title":"Artificial Intelligence in Dermatology: Addressing Algorithmic Bias in Skin of Color.","authors":"Lucas Goetz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"378"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kirsten May, Kyla Jarvis, Ted Van Alstyne, Peter Paul C Lim
{"title":"Extra-intestinal Manifestations of Salmonella in Immunocompetent Pediatric Patients: A Case Series.","authors":"Kirsten May, Kyla Jarvis, Ted Van Alstyne, Peter Paul C Lim","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>This case series discusses five cases of invasive Nontyphoidal Salmonella (iNTS) infections. These presentations are atypical in healthy children without immunodeficiency or hemoglobinopathy.</p><p><strong>Methods: </strong>We present five cases of iNTS in otherwise healthy children that were not previously known to have established risk factors. An abridged literature review of iNTS was performed.</p><p><strong>Results: </strong>The patients in this case series were older than previously documented reports of iNTS with a mean age of 12.4 years. Each patient was immunocompetent aside from hypogammaglobulinemia in case 5. These cases had variable presentations ranging from bacteremia, septic arthritis, abscesses, pyelonephritis, transaminitis and meningismus. Additionally, our patients had hospital durations with an average of 4.8 days.</p><p><strong>Conclusion: </strong>While iNTS most commonly affects pediatric patients less than 5 years of age with hemoglobinopathy or immunodeficiency, this is not always the case. Thus, a high index of suspicion is needed for iNTS: Blood cultures should be collected and focal infections ruled out. Additionally, patients should receive an immunologic and hematologic workup.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"368-375"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahd J Nazir, Syed Sami N Zafar Ahmed, Zahed Barak, Krishna Suresh, Neil K Bansal, Jawad Nazir
{"title":"Disseminated Coccidioides posadasii Infection in Pregnancy Complicated by Central Nervous System Disease: A Case Report and Review.","authors":"Fahd J Nazir, Syed Sami N Zafar Ahmed, Zahed Barak, Krishna Suresh, Neil K Bansal, Jawad Nazir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coccidioidomycosis is typically a self-limited pulmonary infection but may cause severe disseminated disease in pregnancy. Central nervous system involvement is the most serious manifestation and can be diagnostically challenging due to nonspecific symptoms. We report a case of disseminated Coccidioides posadasii infection in a pregnant patient presenting with persistent headache subsequently complicated with coccidioidal meningitis and hydrocephalus requiring neurosurgical intervention. This case highlights the importance of maintaining suspicion for endemic fungal infections in pregnant patients with unexplained neurologic symptoms and emphasizes the need for early, multidisciplinary management to prevent significant morbidity and mortality for both the mother and the fetus.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"350-353"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dawood Shehzad, Logan Johnke, Muhammad Faisal Riaz, Amr Moustafa, Hammad Chaudhry, Dawlat Khan
{"title":"Impact of Frailty on Outcomes After Transcatheter Edge-to-Edge Repair with MitraClip (from the National Inpatient Sample 2021-2022).","authors":"Dawood Shehzad, Logan Johnke, Muhammad Faisal Riaz, Amr Moustafa, Hammad Chaudhry, Dawlat Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Frailty profoundly influences procedural outcomes in cardiovascular interventions. Although its effect is well established in transcatheter aortic valve replacement (TAVR), data remains limited for mitral transcatheter edge-to-edge repair (TEER). We evaluated the impact of frailty (defined by the Johns Hopkins Adjusted Clinical Groups Indicator) and the prevalence of associated comorbidities on in-hospital outcomes after TEER.</p><p><strong>Methods: </strong>Adults (≥18 years) undergoing TEER were identified from the National Inpatient Sample (NIS) 2021-2022. Frailty was defined per the Adjusted Clinical Group (ACG) criteria, and patients were categorized as frail or nonfrail. The primary endpoint was in-hospital mortality. The secondary endpoints included: length of stay (LOS), hospitalization costs, and comorbidities associated with mortality. Univariate and multivariable logistic and linear regressions adjusted for demographics and comorbidities were conducted where appropriate.</p><p><strong>Results: </strong>Among 26,196 weighted TEER hospitalizations, 2,130 (8.13 %) met frailty criteria. Frailty was associated with four-fold higher odds of in-hospital mortality (OR 4.03, 95 % CI 2.97-5.44, p < 0.001). Independent predictors of mortality included end-stage renal disease (ESRD, OR 13.67), heart failure (OR 3.38), chronic liver disease (OR 2.60), and CKD stage 3-5 (OR 1.92). Obesity showed no association with mortality. Frail patients had longer LOS (10.9 vs 3.3 days, p < 0.001) and higher mean costs ($377,688 vs $230,650, p < 0.001).</p><p><strong>Conclusions: </strong>Frailty is present in approximately 8 % of TEER patients and is strongly associated with increased mortality and resource utilization. Routine frailty screening may help optimize patient selection and post-procedural care.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"345-348"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ellie Gubbrud, Mackenzie Gustafson, Will Brown, Sherlon Sinclair
{"title":"Acute Acalculous Cholecystitis as a Rare Manifestation of Thyroid Storm: A Case Report.","authors":"Ellie Gubbrud, Mackenzie Gustafson, Will Brown, Sherlon Sinclair","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Acute acalculous cholecystitis (AAC) is an uncommon, but potentially life-threatening inflammation of the gallbladder without gallstones. While typically seen in critically ill patients, its association with thyroid storm is exceedingly rare.</p><p><strong>Case presentation: </strong>We report a 28-year-old male with a history of Hashimoto's thyroiditis and Graves' disease, nonadherent to methimazole, who presented with dizziness, palpitations, epigastric pain, and nausea. Examination revealed tachycardia, hypertension, and atrial fibrillation with rapid ventricular response. Laboratory evaluation showed severe thyrotoxicosis (Free T4 5.63 ng/dL, Total T3 527 ng/dL, TSH <0.01 μIU/mL) and mildly elevated liver function tests. Abdominal imaging demonstrated gallbladder wall thickening without cholelithiasis, consistent with AAC. The patient was managed conservatively with antithyroid therapy, beta-blocker, IV fluids, and antibiotics. He experienced significant symptomatic improvement, and follow-up confirmed resolution of abdominal symptoms.</p><p><strong>Discussion: </strong>This case report highlights AAC as a rare, but clinically relevant complication of thyroid storm. Early recognition, appropriate imaging and management of underlying hyperthyroidism can allow successful non-operative treatment in patients. Clinicians should maintain a high index of suspicion for AAC in patients presenting with abdominal pain and severe thyrotoxicosis.</p><p><strong>Conclusion: </strong>Further research is needed to clarify the pathophysiological link between thyrotoxicosis and AAC as well as development of nonoperative management guidelines.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"358-361"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Images in Medicine: NSTEMI Due to Thrombosed Aneurysm of the Left Main and Left Circumflex Coronary Artery.","authors":"Dawood Shehzad, Hammad Chaudhry","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"376-377"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebecca Hofer, Tiffany Knecht, Maureen Hurley, Leah Naasz, Daniel Megard
{"title":"Review of Feasibility and Impact of Point-of-Care Ultrasound Use in Rural Guatemala Outreach Clinics.","authors":"Rebecca Hofer, Tiffany Knecht, Maureen Hurley, Leah Naasz, Daniel Megard","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Despite advances in medical technology, diagnostic gaps persist in low-resource settings. Point-of-care ultrasound (POCUS) is a portable, accessible tool that can expedite diagnosis, guide treatment, and improve clinical outcomes. However, few studies quantify its real-world impact, specifically in low-resource settings. This study seeks to evaluate how POCUS influences clinical diagnosis and treatment decisions in areas with limited radiologic support, as well as highlight cases where its use influenced patient management.</p><p><strong>Methods: </strong>POCUS use during five days of a primary care outreach clinic in five rural Guatemalan communities was documented. A POCUS-certified physician conducted abdominal, pelvic, renal, and thyroid scans with participating medical students. Verbal consent was obtained via certified translators and all images were deidentified. Data on pre-imaging suspicion and post-imaging diagnosis were documented, and diagnoses were categorized as confirmed, ruled out, or changed.</p><p><strong>Results: </strong>Of 219 patients seen, a total of 27 ultrasounds were performed. The most frequent type of scan was pelvic (n=12, 44.4%), followed by abdominal (n=11, 40.7%). Fourteen scans (51.9%) confirmed the suspected diagnosis, 10 (37.0%) ruled out structural abnormalities (i.e. leiomyomas, bladder abnormalities), and 3 (11.1%) changed diagnosis.</p><p><strong>Conclusion: </strong>POCUS use demonstrated practical utility that can allow physicians to offer definitive diagnoses and treatment options in communities with limited radiology support. This readily accessible imaging modality demonstrated usefulness in the diagnosis of conditions like hyperthyroidism, cholelithiasis, and numerous gynecologic conditions. Its utilization in primary care outreach clinics offers a method to enhance diagnostic accuracy and should be further explored.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"363-367"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Walk a Mile in Someone Else's Shoes: An Experiential Approach to Cultivating Compassion in Future Physicians in a Pre-Post Intervention Study.","authors":"Phebie Rossi, Michelle Schimelpfenig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study examined whether experiential role-play could enhance empathy and compassion in medical students by simulating the experiences of underserved populations. Fourteen third-year students at the University of South Dakota Sanford School of Medicine (USD SSOM) participated in scenarios involving homelessness, intimate partner violence, and undocumented status. Pre- and post-intervention surveys measured students' understanding of community barriers, confidence in accessing local resources, and perceived empathy. Results showed significant improvements in knowledge and confidence related to social determinants of health, though self-reported empathy did not change significantly. Despite this, students rated the experience as highly effective in fostering compassion and preparing them for empathetic clinical care.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 8","pages":"354-357"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148841475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Origins of the Stethoscope.","authors":"Andrew Kremer, H Bruce Vogt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 7","pages":"294-295"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148649364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bugs and Beyond: A Case of Chronic Osteomyelitis.","authors":"Colewyn Knoblich, Jared Daniel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Osteomyelitis is the infection of bone that can be either acute or chronic. Infection occurs through hematogenous spread and bacterial seeding from a distant site of infection, growth of nearby infected tissue, or direct inoculation from trauma or surgery. Hematogenous spread is more common in children and can cause spontaneous osteomyelitis. Chronic osteomyelitis is a rare occurrence that is often prevented by prompt diagnosis and treatment. This case report demonstrates a rare occurrence of chronic osteomyelitis with osteonecrosis and pathological fracture in a young patient with delayed diagnosis and management.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"79 7","pages":"314-317"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148649394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}