Clinical Microbiology Newsletter最新文献_第3页

Laboratory diagnosis of nontuberculous mycobacteria – an update – Part 3*: Molecular diagnostics, environmental testing, and notifiable conditions 非结核分枝杆菌的实验室诊断-更新-第3部分*：分子诊断、环境检测和应通报的条件

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-06-25 DOI: 10.1016/j.clinmicnews.2025.06.008

Barbara A. Brown-Elliott , Joseph O. Falkinham 3rd , Jennifer L. Furlong , David E. Griffith , Kimberlee A. Musser , Nicole M. Parrish , Max Salfinger , Janet E. Stout , Nancy L. Wengenack , Adrian M. Zelazny

{"title":"Laboratory diagnosis of nontuberculous mycobacteria – an update – Part 3*: Molecular diagnostics, environmental testing, and notifiable conditions","authors":"Barbara A. Brown-Elliott , Joseph O. Falkinham 3rd , Jennifer L. Furlong , David E. Griffith , Kimberlee A. Musser , Nicole M. Parrish , Max Salfinger , Janet E. Stout , Nancy L. Wengenack , Adrian M. Zelazny","doi":"10.1016/j.clinmicnews.2025.06.008","DOIUrl":"10.1016/j.clinmicnews.2025.06.008","url":null,"abstract":"<div><div>The nontuberculous mycobacteria (NTM) are now more frequently encountered in the laboratory compared to 20-30 years ago. New media and molecular assays have been introduced for the accurate detection and identification of an increased number of new NTM species. Furthermore, antimicrobial drug resistance genes have been characterized for the detection of macrolide and aminoglycoside resistance. NTM are often involved in nosocomial outbreaks where water sources are often the culprit. The authors of this 3-part publication aimed to provide an update on current clinical diagnostics for NTM as well as information about testing water or environmental samples for NTM, since this is often requested of the clinical laboratory. For an NTM disease to develop, a trifecta of elements/forces are in play: host characteristics, the NTM, and the environment.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"52 ","pages":"Pages 50-60"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Microbe snapshots: Measles virus 微生物快照：麻疹病毒

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-06-10 DOI: 10.1016/j.clinmicnews.2025.06.002

Kevin Fonseca

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Lophomonas sp. infection in a patient with chronic rhinitis 慢性鼻炎患者的单胞菌感染

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-08-14 DOI: 10.1016/j.clinmicnews.2025.08.002

Arijit Pal , Arkaprabha Sau

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Laboratory diagnosis of nontuberculous Mycobacteria – an update – Part 2: Specimen collection and laboratory work-up 非结核分枝杆菌的实验室诊断-更新-第2部分：标本收集和实验室检查

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-07-22 DOI: 10.1016/j.clinmicnews.2025.05.005

Barbara A. Brown-Elliott , Joseph O. Falkinham 3rd , Jennifer L. Furlong , David E. Griffith , Kimberlee A. Musser , Nicole M. Parrish , Max Salfinger , Janet E. Stout , Nancy L. Wengenack , Adrian M. Zelazny

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Vibrio cholerae cystitis following geothermal hot springs exposure in California 加州地热温泉暴露后的霍乱弧菌膀胱炎

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-06-16 DOI: 10.1016/j.clinmicnews.2025.06.004

Geneviève Amaral , Christopher F. Lowe , Gordon Ritchie , Conor Broderick , Michael Payne , Aleksandra Stefanovic , Nancy Matic , Nick P.G. Gauthier , Samuel D. Chorlton , Patrick Tang , Marc G. Romney

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Cholangitis caused by Streptococcus gordonii: A case report and review of the literature 戈多氏链球菌所致胆管炎1例报告及文献复习

Clinical Microbiology Newsletter Pub Date : 2025-09-01 Epub Date: 2025-06-18 DOI: 10.1016/j.clinmicnews.2025.06.007

Kaoutar Jamal , Said Ezrari , Abderrazak Saddari , Sabah Mokhtari , Zahi Ismaili , Elmostapha Benaissa , Yassine Ben Lahlou , Mostafa Elouennass , Adil Maleb

{"title":"Cholangitis caused by Streptococcus gordonii: A case report and review of the literature","authors":"Kaoutar Jamal , Said Ezrari , Abderrazak Saddari , Sabah Mokhtari , Zahi Ismaili , Elmostapha Benaissa , Yassine Ben Lahlou , Mostafa Elouennass , Adil Maleb","doi":"10.1016/j.clinmicnews.2025.06.007","DOIUrl":"10.1016/j.clinmicnews.2025.06.007","url":null,"abstract":"<div><div><em>Streptococcus gordonii</em> is a commensal bacterium rarely described in human infections. Herein, we describe a case of cholangitis due to <em>Streptococcus gordonii</em>. A 62-year-old woman, known to have had cholelithiasis, with history of gastroesophageal reflux and a brother who died of nasopharyngeal carcinoma, was admitted due to abdominal pain, fever, and jaundice. Abdominal computed tomography showed moderate dilation of the common and intrahepatic bile duct upstream of stones the distal ampullary portion, and cholelithiasis. The patient underwent endoscopic retrograde cholangiopancreatography and intraoperative sampling of bile fluid. The patient received empiric antibiotic therapy based on parenteral ceftriaxone and metronidazole. The microbiological analysis revealed the exclusive presence of <em>Streptococcus gordonii</em>. The initial treatment was maintained for 5 days and then replaced by oral amoxicillin-clavulanate and metronidazole. The clinical evolution was favorable. We present here a case of cholangitis caused by <em>Streptococcus gordonii</em> and a literature review.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"52 ","pages":"Pages 24-30"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Purulent pericarditis caused by Kytococcus schroeteri: Case report and literature review 鼠形Kytococcus schroeteri致化脓性心包炎1例并文献复习

Clinical Microbiology Newsletter Pub Date : 2025-06-01 Epub Date: 2025-04-21 DOI: 10.1016/j.clinmicnews.2025.04.002

Abir Yahyaoui , Abderrazak Saddari , Said Ezrari , Elmostapha Benaissa , Yassine Ben Lahlou , Mostafa Elouennass , Adil Maleb

{"title":"Purulent pericarditis caused by Kytococcus schroeteri: Case report and literature review","authors":"Abir Yahyaoui , Abderrazak Saddari , Said Ezrari , Elmostapha Benaissa , Yassine Ben Lahlou , Mostafa Elouennass , Adil Maleb","doi":"10.1016/j.clinmicnews.2025.04.002","DOIUrl":"10.1016/j.clinmicnews.2025.04.002","url":null,"abstract":"<div><div><em>Kytococcus schroeteri</em> is a Gram-positive Cocci, considered a saprophyte of human skin, which can cause severe infections. Diagnosis is difficult due to non-specific clinical manifestations that vary according to the host's immune status and the presence or absence of implantable devices. It appears that this pathogen has the potential to acquire resistance to multiple antibiotic classes, which only exacerbates the challenge of curing it. We report a rare case of <em>K. schroeteri</em> purulent pericarditis in a 40-year-old woman who underwent surgery to implant an implantable catheter chamber in order to receive chemotherapy for her left breast tumor, associated with a pericardial effusion requiring emergency drainage. Microbiological identification by matrix-assisted laser desorption-time-of-flight mass spectrometry (MALDI-TOF MS) demonstrated the exclusive presence of <em>K. schroeteri</em> from the subculture of the aerobic enrichment broth of the pericardial fluid. Prompt initiation of antibiotic therapy adapted to the results of the antimicrobial susceptibility testing led to clinical and biological improvement, marked by normalization of inflammatory indicators. This case sheds light on an emerging microbiological pathogen with the potential to affect a variety of tissues, putting the vital prognosis at risk, and underlines the need for heightened clinical suspicion and an adapted therapeutic approach in immunocompromised patients.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"51 ","pages":"Pages 21-25"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The need for clinical, public health, industry partnerships and collaborations 临床、公共卫生、行业伙伴关系和协作的需要

Clinical Microbiology Newsletter Pub Date : 2025-06-01 Epub Date: 2025-04-14 DOI: 10.1016/j.clinmicnews.2025.04.001

Filipe Cerqueira , Kristen L. Jurcic Smith , Kara J. Levinson , Diana R. Hernández , Andrea M. Prinzi

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Chikungunya: The silent threat in the shadows 基孔肯雅热：阴影中的无声威胁

Clinical Microbiology Newsletter Pub Date : 2025-06-01 Epub Date: 2025-02-20 DOI: 10.1016/j.clinmicnews.2025.02.001

Ambreen Talib , Rabbya Rayan Shah , Rameen Atique , Hafiza Arshi Saeed , Ayesha Haidar , Ayesha Nadeem , Areesha Naveed , Javeria Sharif , Ayesha Muazzam , Abdul Samad

{"title":"Chikungunya: The silent threat in the shadows","authors":"Ambreen Talib , Rabbya Rayan Shah , Rameen Atique , Hafiza Arshi Saeed , Ayesha Haidar , Ayesha Nadeem , Areesha Naveed , Javeria Sharif , Ayesha Muazzam , Abdul Samad","doi":"10.1016/j.clinmicnews.2025.02.001","DOIUrl":"10.1016/j.clinmicnews.2025.02.001","url":null,"abstract":"<div><div>Chikungunya virus (CHIKV) is mostly related to arboviruses that cause serious public health threats. CHIKV belongs to the family <em>Togaviridae</em> and genus <em>Alphavirus, the cause of chikungunya</em> fever (CHIKF), an arthritogenic disease. Its distinguishing feature is intense arthralgia that lasts for months and even years in susceptible persons. CHIKF is a re-emerging disease that has occurred as an epidemic in Africa across Asia and America in recent decades and has caused global health threats, leading to outbreaks that impact millions of people. Pathogenesis of CHIKV has been researched for >50 years, but no evidence has led to the development of vaccines or drugs. Current management involves reliving symptoms by supportive care to improve the quality of patients’ lives. The ongoing outbreaks of CHIKV show that there is a crying need to understand the pathogenesis of CHIKV. It is important to comprehend CHKIV to develop prevention and control measures for the spread of the disease. This review aims to provide comprehensive knowledge about CHIKV, shedding light on its host-related factors, vector-related factors, and complicated interactions of viral genetics. By following these complex interactions, this review aims to communicate the studies and research about CHIKV, offering strategies that lead to more effective prevention and control measures for this re-emerging global health threat.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"51 ","pages":"Pages 1-14"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Morganella morganii: an opportunistic multidrug-resistant pathogen isolated in ascitic fluid in an old man, case report and literature review 莫氏摩根菌：一种从老人腹水中分离出的机会性多重耐药病原菌，病例报告及文献复习

Clinical Microbiology Newsletter Pub Date : 2025-06-01 Epub Date: 2025-04-24 DOI: 10.1016/j.clinmicnews.2025.04.004

Ismail Faiz , Abderrazak Saddari , Said Ezrari , Mohammed Lahmer , Samir Kaddouri , Elmostafa Benaissa , Yassine BenLahlou , Mostafa Elouennass , Adil Maleb

{"title":"Morganella morganii: an opportunistic multidrug-resistant pathogen isolated in ascitic fluid in an old man, case report and literature review","authors":"Ismail Faiz , Abderrazak Saddari , Said Ezrari , Mohammed Lahmer , Samir Kaddouri , Elmostafa Benaissa , Yassine BenLahlou , Mostafa Elouennass , Adil Maleb","doi":"10.1016/j.clinmicnews.2025.04.004","DOIUrl":"10.1016/j.clinmicnews.2025.04.004","url":null,"abstract":"<div><div><em>Morganella morganii</em> is commonly found in nature and is also part of the normal intestinal flora in humans and animals. Although typically an opportunistic pathogen, it is rarely isolated in human infections. Infections caused by this bacterium primarily include postoperative wound infections, urinary tract infections, sepsis, abscesses, chorioamnionitis, and cellulitis. The emergence of multidrug-resistant strains poses a significant public health concern, as these strains can lead to severe or even fatal infections in vulnerable patients. We report the case of a 94-year-old immunocompromised patient admitted to the emergency department with dyspnea, significant ascites, and prolonged fever. A C-TAP scan revealed chronic liver disease with large-volume ascites. Laboratory tests showed a mild inflammatory response (CRP: 14 mg/L), low prothrombin time (PT: 56%), hypoalbuminemia (19 g/L), pancytopenia, and macrocytic anemia. Cytobacteriological analysis of the ascitic fluid revealed a significant neutrophilic response and the growth of <em>Morganella morganii</em>. Antibiotic susceptibility testing showed susceptibility to carbapenems, fluoroquinolones, co-trimoxazole, and chloramphenicol, while resistance was observed against penicillins (aminopenicillins, carboxypenicillins, ureidopenicillins), cephalosporins, fosfomycin/trometamol, and aminoglycosides. The multidrug-resistant strain of <em>Morganella morganii</em> in this case demonstrated concerning resistance to most <em>β</em>-lactams, aminoglycosides, and fosfomycin/trometamol. Given its increasingly opportunistic nature, multidrug resistance, and potential to cause severe nosocomial infections, clinicians must consider this bacterium during the diagnostic process.</div></div>","PeriodicalId":39211,"journal":{"name":"Clinical Microbiology Newsletter","volume":"51 ","pages":"Pages 31-36"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0