African Journal of Infectious Diseases最新文献_第2页

GENETIC DETERMINANTS OF ANTIBIOTIC RESISTANCE AND VIRULENCE IN Staphylococcus aureus ISOLATES FROM HOSPITAL SURFACES IN HIGH-RISK AREAS OF LOJA, ECUADOR. 厄瓜多尔洛哈高风险地区医院表面金黄色葡萄球菌分离株抗生素耐药性和毒力的遗传决定因素。

African Journal of Infectious Diseases Pub Date : 2025-10-17 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2S.10

Lima-Quizhpe Cristina, Andrade-Tacuri Carlos, Ortiz-Tejedor Jonnathan, Orellana-Bravo Paola, Toledo-Andrade Karla

{"title":"GENETIC DETERMINANTS OF ANTIBIOTIC RESISTANCE AND VIRULENCE IN Staphylococcus aureus ISOLATES FROM HOSPITAL SURFACES IN HIGH-RISK AREAS OF LOJA, ECUADOR.","authors":"Lima-Quizhpe Cristina, Andrade-Tacuri Carlos, Ortiz-Tejedor Jonnathan, Orellana-Bravo Paola, Toledo-Andrade Karla","doi":"10.21010/Ajidv19i2S.10","DOIUrl":"10.21010/Ajidv19i2S.10","url":null,"abstract":"Background: Staphylococcus aureus is a microorganism associated with nosocomial infections, characterized by its high pathogenicity and antibiotic resistance, posing a critical risk in hospital environments. This study aimed to determine its presence, antibiotic susceptibility, and the detection of virulence, adhesion, and regulatory genes on hospital surfaces using phenotypic and molecular methods.Materials and methods: A total of 200 surface samples were collected from a secondary-level hospital, including clinical wards, ICU, and emergency areas. S. aureus was isolated using phenotypic techniques (mannitol, coagulase, DNase) and genotypic methods (detection of nucA and femB). Antimicrobial susceptibility was evaluated using the Kirby-Bauer method. Polymerase Chain Reaction (PCR) was employed to identify resistance and virulence genes.Results: S. aureus was detected in 7.5% of the samples analyzed, with higher prevalence in Clinic I and Emergency areas. The most contaminated surfaces included door handles, tables, and keyboards, identified as critical transmission points. Among the isolated strains, 66.6% were resistant to penicillin, while 100% were sensitive to methicillin and vancomycin. Virulence genes (tst, sea) were present in 26.6% and 13.3% of the strains, respectively. Regarding regulatory genes, agrI (73.3%) was the most common, followed by agrIII. For adhesion factors, icaD and icaC were the most frequently detected genes.Conclusion: These findings highlight the pathogenic potential of S. aureus and its ability to persist on inert surfaces, representing a significant risk for infection transmission.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2 Suppl","pages":"78-88"},"PeriodicalIF":0.0,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12627219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VACCINES OVER ANTIBIOTICS: SAUDI ARABIA'S JOURNEY OF MANAGING PEDIATRIC BACTERIAL MENINGITIS. 疫苗胜过抗生素：沙特阿拉伯管理儿童细菌性脑膜炎之旅。

African Journal of Infectious Diseases Pub Date : 2025-10-17 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2S.6

Alnasser Yossef, Bin Obaid M Nada, Bamarei M Noura, Alshehri S Aseel, Jakhete A Akhilesh, Binkhamis Khalifa

{"title":"VACCINES OVER ANTIBIOTICS: SAUDI ARABIA'S JOURNEY OF MANAGING PEDIATRIC BACTERIAL MENINGITIS.","authors":"Alnasser Yossef, Bin Obaid M Nada, Bamarei M Noura, Alshehri S Aseel, Jakhete A Akhilesh, Binkhamis Khalifa","doi":"10.21010/Ajidv19i2S.6","DOIUrl":"10.21010/Ajidv19i2S.6","url":null,"abstract":"Background: Saudi Arabia had high rates of bacterial meningitis in the late 90s. Children are at highest risk of this devastating disease with poor outcomes.Objective: The study aims to evaluate the prevalence, causative pathogens, and antibiotic resistance patterns in pediatric bacterial meningitis cases at a tertiary hospital in Riyadh, Saudi Arabia.Materials and methods: Single-center retrospective chart review and cross-sectional methodology was conducted at King Saud University Medical City (KSUMC) from 2015 to 2023.Result: Reviewing 8 years of CSF culture results only yielded 37 cases. This is only 0.5% of total hospital admissions over 8 years. The majority of cases were for children under the age of 2 years (82%). Gender of cases was almost equal and there was no seasonal variation. The most common organisms were gram-positive (14, 38%) including Group B streptococcus (GBS) (4, 11%), Streptococcus pneumoniae (4, 11%). Gram-negative organisms caused 8 cases (22%) by 5 different organisms. There was no Haemophilus influenza type B or meningococcus found in any of the CSF cultures. The single sample of Staphylococcus aureus was methicillin-resistant Staphylococcus aureus (MRSA) and three gram-negative organisms were multidrug resistant.Conclusion: Saudi Arabia provides an example of the success of a mass vaccination program to curb the burden of pediatric bacterial meningitis. Future efforts should focus on antibiotic stewardship, mass screening of GBS, and adopting additional strains for the pneumococcus vaccine. Further research is needed to address the rising number of gram-negative organisms causing pediatric bacterial meningitis in Saudi Arabia and globally.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2 Suppl","pages":"45-53"},"PeriodicalIF":0.0,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12627222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BLOOD URINE POSITIVITY RATE DIPSTICK METHOD ON THE INCIDENCE OF ANEMIA IN URINARY TRACT INFECTION PATIENTS. 血尿阳性率试纸法对尿路感染患者贫血发生率的影响。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.2

Siti Zaetun, Lalu Srigede

{"title":"BLOOD URINE POSITIVITY RATE DIPSTICK METHOD ON THE INCIDENCE OF ANEMIA IN URINARY TRACT INFECTION PATIENTS.","authors":"Siti Zaetun, Lalu Srigede","doi":"10.21010/Ajidv19i2.2","DOIUrl":"10.21010/Ajidv19i2.2","url":null,"abstract":"Background: The prevalence of anemia in children suffering from urinary tract infections with positive hematuria is very high. UTI is confirmed by a complete urine examination including macroscopic, chemical and microscopic examinations. Chemical examination can be carried out using the dipstick method, while urine microscopy involves looking at the image of the urine sediment. One of the parameters on the dipstick is blood. Examination with a reagent strip (dipstick) function to detect erythrocytes, free hemoglobin and myoglobin. So, the presence of erythrocytes, myoglobin or hemoglobin in the urine will give a positive result on the urine blood dipstick parameters, which means hematuria occurs.Materials and methods: This is a cross-sectional analytical observational method, namely by comparing the results of blood urine examination using the dipstick method, with the results of the erythrocyte index and hemoglobin levels on the incidence of anemia in UTI patients.Results: The results of the blood urine dipstick examination obtained the highest positive value of 3. The average values for Hb, MCV, MCH, MCHC were respectively 10.9 g/dL, 83.3 fL, 28.5 pg, and 34.24%.Conclusion: The results of the Pearson correlation test obtained a degree of relationship of -0.363 which indicates a weak correlation. Blood urine is negatively related to the incidence of anemia (Hb levels), so that the higher the positive blood urine value, the lower the Hb value.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DETERMINANTS AND MAPPING OF LEPTOSPIROSIS IN KEBUMEN, INDONESIA: CASE-CONTROL STUDY. 印度尼西亚克布门钩端螺旋体病的决定因素和制图：病例对照研究。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.6

Lestari Mugi Rahayu, Nurcandra Fajaria, Buntara Arga, Simanjorang Chandrayani

{"title":"DETERMINANTS AND MAPPING OF LEPTOSPIROSIS IN KEBUMEN, INDONESIA: CASE-CONTROL STUDY.","authors":"Lestari Mugi Rahayu, Nurcandra Fajaria, Buntara Arga, Simanjorang Chandrayani","doi":"10.21010/Ajidv19i2.6","DOIUrl":"10.21010/Ajidv19i2.6","url":null,"abstract":"Background: Leptospirosis is a health concern with a high mortality rate. As of 2022, 9.8% of Indonesians are vulnerable to leptospirosis, and Kebumen Regency has been recognized as an endemic area since 2012. This study aims to identify the determinants and map the incidence of leptospirosis in Kebumen, Indonesia, in 2023.Material and methods: This study used a 1:1 sample of 53 cases and 53 controls in a case-control study design. Each group was sampled using a purposive sampling technique. Cases were defined as individuals seeking care at a health center or hospital and identified as leptospirosis patients in 2023, while controls were individuals living nearest to the cases. Data analysis for this study involved the use of a logistic regression model.Results: Individuals with a history of wounds have 40.20 times higher odds of experiencing leptospirosis. Men have 2.58 times higher odds of experiencing leptospirosis, while poor use of personal protective equipment (PPE) increases the odds by 2.27. Leptospirosis risk is elevated in areas where rats and standing water are prevalent, as these factors are typically found nearby. Furthermore, pets at risk are commonly found in high-risk areas.Conclusion: History of wounds, sex, and use of PPE are factors that can predict the incidence of leptospirosis. Environmental determinant mapping is observed in high-density, geographically proximate locations.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"50-59"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE RELATIONSHIP BETWEEN SCHOOL ENVIRONMENT CONDITION AND DENGUE HEMORRHAGE FEVER INCIDENCE AT PUBLIC ELEMENTARY SCHOOL. 公立小学校园环境状况与登革出血热发病的关系。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.7

Selamat Ginting, Hariati Hariati, Friska Ernita Sitorus, Jekson Martiar Siahaan

{"title":"THE RELATIONSHIP BETWEEN SCHOOL ENVIRONMENT CONDITION AND DENGUE HEMORRHAGE FEVER INCIDENCE AT PUBLIC ELEMENTARY SCHOOL.","authors":"Selamat Ginting, Hariati Hariati, Friska Ernita Sitorus, Jekson Martiar Siahaan","doi":"10.21010/Ajidv19i2.7","DOIUrl":"10.21010/Ajidv19i2.7","url":null,"abstract":"Background: Dengue cases in Indonesia remain a significant public health concern, with incidence rates increasing over the years. The school environment, including lighting, humidity, temperature, and ventilation, plays a crucial role in the spread of Dengue Hemorrhagic Fever (DHF). This study aims to analyze the relationship between school environmental conditions and DHF incidence.Materials and methods: This was an analytical observational study with a cross-sectional design. The sample consisted of 157 individuals selected using simple random sampling. Data collection was conducted from August to October 2023 using a validated questionnaire assessing school environmental conditions and DHF incidence. Statistical analysis was performed using chi-square and logistic regression tests with a significance level of p < 0.05.Results: School environmental factors significantly associated with DHF incidence included lighting (p = 0.008, PR = 1.82), humidity (p = 0.008, PR = 1.75), temperature (p = 0.045, PR = 1.498), and screen ventilation (p = 0.000, PR = 2.26). Logistic regression analysis identified humidity (OR = 7.16; 95% CI, 2.09-38.37) and ventilation (OR = 18.12; 95% CI, 3.36-56.70) as the most influential factors.Conclusion: The incidence of DHF is closely related to school environmental conditions. Preventive measures focusing on environmental cleanliness and improved ventilation could significantly reduce the risk of dengue transmission among school children.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"60-65"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE REPLICATION EFFICIENCY OF DENGUE VIRUS SEROTYPE 1 ISOLATED FROM PATIENTS WITH DENGUE FEVER IN HUMAN HEPATOCYTE CELL LINES. 从登革热患者分离的血清1型登革热病毒在人肝细胞系中的复制效率。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.4

Geni Lenggo, Widodo Lovendo Ilham, Swestikaputri Chrecentia Hanna, Syahrurachman Agus, Dewi Beti Ernawati

{"title":"THE REPLICATION EFFICIENCY OF DENGUE VIRUS SEROTYPE 1 ISOLATED FROM PATIENTS WITH DENGUE FEVER IN HUMAN HEPATOCYTE CELL LINES.","authors":"Geni Lenggo, Widodo Lovendo Ilham, Swestikaputri Chrecentia Hanna, Syahrurachman Agus, Dewi Beti Ernawati","doi":"10.21010/Ajidv19i2.4","DOIUrl":"10.21010/Ajidv19i2.4","url":null,"abstract":"Background: The Efficiency of viral replication in cells depends on the capability of supporting virus replication by the cells. We characterized the effectiveness of Dengue Virus Serotype 1 (DENV-1) replication in various cell lines and various multiplicity of infection (MOI) starting from 2 FFU/cell up to 0,3125 FFU/cell.Materials and method: We used HepG2 and Huh-7 human hepatocyte cell lines and in addition, we also used non-human kidney cells (Vero cells). DENV-1 strain IDS 11/2010 was isolated from DF patients and previously propagated in Huh7 and Vero cells as DENV-1-adapted Huh-7 and DENV-1-adapted Vero cells, respectively. Huh7 cells, Hep G2 cells, and Vero cells were infected with DENV-1 at various MOI and incubated for 48 hours at 370C with 5% CO2. DENV-infected cells were determined by indirect immuno-peroxidase staining using 3,3'-Diaminobenzidine (DAB). DENV-1 infected cells as foci were counted under inverted light microscopy and were used to determine the virus titer.Results: The virus was adapted to Huh-7 and Vero cells, with results showing that Vero cells exhibited the highest replication efficiency, evidenced by significant viral titers. Among human hepatocyte cell lines, DENV-1 demonstrated greater replication in Huh-7 cells than in HepG2 cells. Notably, no foci formation was observed in HepG2 cells after 48 hours of infection.Conclusion: These findings underscore the suitability of Vero and Huh-7 cells as optimal environments for DENV-1 replication, offering valuable insights for enhancing laboratory diagnostics and advancing antiviral strategies and vaccine development against DENV-1.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FAMILY SUPPORT, MOTIVATION, AND PATIENT ADHERENCE TO TUBERCULOSIS TREATMENT: INSIGHTS FROM INDONESIA. 家庭支持、动机和患者对结核病治疗的依从性：来自印度尼西亚的见解。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.5

Nindrea Ricvan Dana, Ming Long Chiau, Agustian Dede Rahman

{"title":"FAMILY SUPPORT, MOTIVATION, AND PATIENT ADHERENCE TO TUBERCULOSIS TREATMENT: INSIGHTS FROM INDONESIA.","authors":"Nindrea Ricvan Dana, Ming Long Chiau, Agustian Dede Rahman","doi":"10.21010/Ajidv19i2.5","DOIUrl":"10.21010/Ajidv19i2.5","url":null,"abstract":"Background: Tuberculosis (TB) remains a significant public health issue globally, with patient adherence to treatment being critical for successful outcomes.This study aimed to investigate the roles of family support and motivation in influencing adherence to TB treatment in Indonesia.Materials and methods: A cross-sectional study was conducted among patients at four health centers in Padang Municipality, Indonesia, between January and November 2024. A total of 125 respondents diagnosed with drug-sensitive TB and in the second stage of treatment participated. Data were collected through structured interviews using validated questionnaires, assessing family support, motivation, and treatment adherence. Structural Equation Modeling (SEM) was used to analyze the relationships between variables.Results: The findings revealed significant relationships between family support and motivation (β = 0.931, t-value = 47.016, P<0.001), family support and adherence to TB treatment (β = 0.229, t-value = 2.743, P=0.006), and motivation and adherence to TB treatment (β = 0.775, t-value = 9.334, P<0.001).Conclusion: Family support and motivation play crucial roles in enhancing patient adherence to TB treatment. Strategies to strengthen family involvement and patient motivation should be integrated into TB control programs to improve treatment outcomes. Further research is recommended to explore additional factors influencing adherence in different contexts.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"43-49"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DOES COVID-19 PANDEMIC AFFECT THE ELIMINATION OF TUBERCULOSIS? LESSONS LEARNED FROM INDONESIA. COVID-19大流行是否会影响结核病的消除？从印度尼西亚吸取的教训。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.1

Utomo Budi, Fatmaningrum Widati, Sulistiawati Sulistiawati, Khuen Chan Chow, Fauziyah Shifa, Adnyana I Made Dwi Mertha, Eljatin Dwinka Syafira, Sucipto Teguh Hari

{"title":"DOES COVID-19 PANDEMIC AFFECT THE ELIMINATION OF TUBERCULOSIS? LESSONS LEARNED FROM INDONESIA.","authors":"Utomo Budi, Fatmaningrum Widati, Sulistiawati Sulistiawati, Khuen Chan Chow, Fauziyah Shifa, Adnyana I Made Dwi Mertha, Eljatin Dwinka Syafira, Sucipto Teguh Hari","doi":"10.21010/Ajidv19i2.1","DOIUrl":"10.21010/Ajidv19i2.1","url":null,"abstract":"Background: Tuberculosis is one of the tropical diseases which still exist in the tropical country specifically Indonesia. This study aims to investigate the recent epidemiology of tuberculosis before and during the pandemic of COVID-19.Materials and methods: Data were collected from East Java Health Profile 2019 and 2020 which was provided by East Java Health Officer. Data were extracted and analyzed by statistical software SPSS and QGIS Application for the geographical map interpretation.Results: This study shows that the total cases of tuberculosis in 2019 was 606,985 cases, while in 2020 was decreased to 384,752 cases. The incidence rate of tuberculosis in 2019 was 224.98 per 100,000 populations, while in 2020 was 134.58 per 100,000 populations. The province with the highest amount of tuberculosis in 2019 was West Java with 143,935 cases, and also in 2020 with 90,905 cases. The province with the lowest number of tuberculosis was North Kalimantan with 2,113 cases, while in 2020 were 985 cases. The highest incidence rate of tuberculosis in 2019 was found in Jakarta which was 443,47 per 100,000 population, while in 2020 was found in Papua which was 279.92 per 100,000 population. The lowest incidence rate in 2019 was found in Bali Province which was 102.72 per 100,000 population, while in 2020 was 67.43 per 100,000 population.Conclusion: There was a decrease in TB cases before the COVID-19 pandemic (2019) compared to during the COVID-19 pandemic (2020).","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SPATIAL MODELING OF RISK FACTORS FOR UNDER-FIVE PNEUMONIA IN ROKAN HILIR DISTRICT, INDONESIA. 印度尼西亚rokan hilir地区五岁以下儿童肺炎危险因素的空间建模。

African Journal of Infectious Diseases Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.21010/Ajidv19i2.3

Yusdiana Yusdiana, Sukendi Sukendi, Siregar Yusni Ikhwan, Afandi Dedi

{"title":"SPATIAL MODELING OF RISK FACTORS FOR UNDER-FIVE PNEUMONIA IN ROKAN HILIR DISTRICT, INDONESIA.","authors":"Yusdiana Yusdiana, Sukendi Sukendi, Siregar Yusni Ikhwan, Afandi Dedi","doi":"10.21010/Ajidv19i2.3","DOIUrl":"10.21010/Ajidv19i2.3","url":null,"abstract":"Background: Under-five pneumonia remains a critical health issue in Indonesia. Identifying risk factors using spatial models is crucial for developing effective disease-prevention strategies. This study aimed to identify risk factors and create a spatial model for under-five pneumonia distribution based on regional vulnerability.Materials and methods: This study used a mixed-method approach that integrated mathematical models and GIS to identify risk factors using generalized Poisson regression (GPR) and developed a GIS-based spatial model with inverse distance weighted (IDW) and natural break methods.Results: The GPR model revealed significant associations between under-five pneumonia and population density (β = 0.004, Z-score = 6.118), rainfall (β = 0.002, Z-score = 6.031), malnutrition (β = 1.786, Z-score = 3.696), and health facilities (β = 0.073, Z-score = 13.527). Protective factors included exclusive breastfeeding (β = -0.004, Z-score = -2.874), healthy homes (β = -0.021, Z-score = -9.532), and under-five health service coverage (β = -0.003, Z-score = -2.225). Spatial modeling classified regions into high-risk (5 subdistricts), medium-risk (11 subdistricts), and low-risk (3 subdistricts).Conclusion: This study identified key risk factors and mapped spatial vulnerability for under-five pneumonia. Targeted, integrated interventions in high-risk areas are essential to reduce pneumonia incidence below 12 cases per 1,000 children under five by 2030, aligning with global health goals.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"19 2","pages":"15-32"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum: EFFECT OF PENICILLIUM SPECIES ON THE ANTIBIOTIC RESISTANCE PROFILE OF ALCALIGENES FAECALIS. 勘误：PENICILLIUM SPECECIES 对 ALCALIGENES FAECALIS 抗生素特性的影响。

African Journal of Infectious Diseases Pub Date : 2024-07-04 eCollection Date: 2024-01-01 DOI: 10.21010/Ajidv18i2S.6

Alkhalil S Samia

引用次数: 0