Journal of Gastrointestinal and Digestive System最新文献

{"title":"Mesenteric Lymphangioma with Small Intestinal Volvulus in an Adult","authors":"Hyundong Chae, C. Cho, In-Hwan Kim","doi":"10.4172/2161-069X.1000485","DOIUrl":"https://doi.org/10.4172/2161-069X.1000485","url":null,"abstract":"Lymphangioma occur commonly in the neck and axillae of pediatric patients, caused by an obstruction of the lymphatic flow because of congenital lymphatic malformation. However, mesenteric lmphangioma of the small intestine is a rare tumor that is seldom associated with small bowel volvulus, particularly in adult patients. Although rare, mesenteric lymphangioma can cause volvulus and intestinal obstruction by a torsion of mesentery. We report an unusual case of mesenteric lymphangioma with small bowel volvulus who was suffered from intermittent abdominal pain, treated with surgical resection.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"66 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126399839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemangiopericytoma of the Greater Omentum with Pelvic Metastasis: A Very Rare Occurrence","authors":"S. Bushira","doi":"10.4172/2161-069X.1000486","DOIUrl":"https://doi.org/10.4172/2161-069X.1000486","url":null,"abstract":"Hemangiopericytoma arising from the greater omentum is very rare and only 14 case reports were found in the English literature. Here we report a case of hemangiopericytoma arising from the greater omentum with pelvic metastasis. The case was a 45 year old male patient admitted to our hospital with abdominal pain and swelling. Abdominal ultrasound and computer tomography detected a huge heterogeneously enhancing predominantly solid central abdominal mass with cystic changes. Laparotomy and excision of huge freely mobile highly vascularized mass arising from the greater omentum and multiple deposits on the anterior wall of the rectum was performed. Histological findings confirmed a diagnosis of hemangiopericytoma of the greater omentum with secondary deposits in the pelvis","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122970788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Presentation of Short Bowel Syndrome Complicated with SevereDegree of Nutritional Deficiencies, Nephrocalcinosis and Distal Renal TubularAcidosis","authors":"T. Herath, A. Kulatunga","doi":"10.4172/2161-069X.1000484","DOIUrl":"https://doi.org/10.4172/2161-069X.1000484","url":null,"abstract":"Background: Short bowel syndrome (SBS) is a malabsorptive state due to functional or anatomic loss of extensive segments of small intestine which can lead to nutritional deficiencies and metabolic disarrangements. Here we describe a young patient with short bowel presenting with severe nutritional deficiencies, nephrocalcinosis and distal renal tubular acidosis. Nephrocalcinosis and distal renal tubular acidosis are closely associated and each can lead to the other. There are only rare case reports of short bowel syndrome complicated with nephrocalcinosis and distal RTA and severe degree of metabolic derangement with nutritional deficiencies. And this case highlights the importance of early management of short bowel syndrome in order to prevent long-term complications. Case presentation: A forty two-year-old Sri Lankan male patient who had undergone appendectomy at the age of nineteen years, which was complicated by bowel gangrene and about 240 cm of small bowel was resected. Later he presented with recurrent urolithiasis and urinary tract infections and ten years after the surgery imaging revealed bilateral nephrocalcinosis and obstructive uropathy. Distal Renal tubular acidosis (RTA) was diagnosed at the same time. He also had osteomalacia, proximal myopathy, multiple vitamin deficiencies, mixed deficiency anemia. He was started on calcium, iron supplements, parenteral B12, vitamin D injections and alkali therapy to achieve a normal serum bicarbonate concentration. His calcium and Vitamin D supplementation is currently being monitored with serum calcium, 25-hydroxyvitamin D, serum alkaline phosphatase, serum PTH and urinary calcium/creatinine ratio. Conclusion: Patients with extensive small bowel resection are at risk for nutrient, mineral, and vitamin deficiencies because of the loss of absorptive surface. It can also be complicated with nephrocalcinosis and distal RTA which is rare in short bowel syndrome. It is therefore important to identify patients at risk of short bowel syndrome and institute an early management, follow up plan to prevent complications.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122753146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appendicectomy for Appendicitis and Laparoscopy Training","authors":"E. Ray-Offor, Jebbin Nj","doi":"10.4172/2161-069X.1000483","DOIUrl":"https://doi.org/10.4172/2161-069X.1000483","url":null,"abstract":"Background: Globally, acute appendicitis is the most common cause of acute surgical abdomen with significant morbidity and mortality. Laparoscopy is a notable stride in the improvement of surgical care. Aims: To study the practice of appendicectomy in the tertiary hospital setting of a developing country to know who performs it, when and how. Patients and Methods: A retrospective study of all appendicectomies for acute Appendicitis performed in University of Port Harcourt Teaching Hospital (UPTH) from January 2007 to December 2012. Data were extracted from the theatre records on demographics, anaesthesia, cadre of surgeon, method of operation and operating time. Statistical analysis of data was done using SPSS version 20. Results: A total of 432 appendicectomies for acute appendicitis were performed during the study period. There were 205 males and 217 females with 10 unspecified cases. Four hundred and eight (98.6%) were by open method while 6 (1.4%) underwent laparoscopic appendicectomy. Senior registrars performed most appendectomies 255 (59%) while consultant surgeons performed 83 (19.0%) cases. Conclusions: Surgical trainees perform most of the emergency operations for acute appendicitis. The open method is routinely used however a structured training in laparoscopic appendicectomy especially for surgical trainees is recommended.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132121872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of ethanolic extract of coconut (Cocos nucifera) on aspirin-induced gastric ulcer in albino rats","authors":"Amjad M, Tahir M","doi":"10.4172/2161-069X.1000512","DOIUrl":"https://doi.org/10.4172/2161-069X.1000512","url":null,"abstract":"Statement of problem: Aspirin is extensively used as an analgesic, antipyretic, anti-thrombotic and antiinflammatory drug. It is safe in therapeutic doses but it is toxic in over dosage or in chronic injudicious use, when it causes acute or chronic toxicity respectively. Acute toxicity causes gastric ulceration and bleeding. Gastric ulcer developed when the imbalance occurs between aggressive and defensive factors of the stomach and situation favours aggressive factors enough to cause mucosal damage and lead to ulceration. Many antioxidants have been trying to study their protective effects of aspirin and others NSAID’s induced gastric ulcers. Coconut and its products are known for their antioxidant, antibacterial, anti-diabetic, antithrombotic and antiulcer genic effects. Two different studies are documented about the effect of ethanolic extract of coconut on indomethacin induced gastric ulcers. Both are paradoxical, and show controversy at different doses of extract. The present study, therefore, designed in an attempt to observe the effects of high doses of ethanolic extract of coconut on aspirin induced gastric ulcers. This was conducted at University of Health Sciences Lahore. Thirty rats, weighing 175-220 gm, were divided into six groups and were treated with different doses of extract for 14 days and were sacrificed on 15th day of experiment. Methodology involved staining of stomach with H and E and Masson Trichome staining and was observed for desquamation, mucosal congestion, inflammatory Cells and necrosis. Blood samples were drawn for serum analysis of Super Oxide Dismutase (SOD). \u0000Findings: The results showed that ethanolic extract of coconut helps to heal the stomach ulcers and gives best results at 400 mg/kg dose and also helps to reduce oxidative stress which also helps to heal ulcers. \u0000Conclusion and significance: It was concluded that ethanolic extract of coconut provides a very reliable and cost effective adjunctive therapy to be routinely used in patients who take aspirin and aspirin induced gastric ulcers as well.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126475624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging and Clinical Relevance of Intrahepatic Gall Bladder-A Rare Anomaly","authors":"R. Rastogi, A. Gaur, Y. Gupta, Shourya Sharma, P. Sinha, P. Das, S. Parashar, Vijai Pratap","doi":"10.4172/2161-069X.1000482","DOIUrl":"https://doi.org/10.4172/2161-069X.1000482","url":null,"abstract":"Intrahepatic gall bladder (GB) is an uncommonly encountered condition in clinical practice characterised by ectopic location of GB within the hepatic parenchyma. This condition not only produces difficulty in clinical diagnosis of various GB diseases especially cholecystitis and carcinoma but also in their management including cholecystectomy. Hence, this article discusses imaging diagnosis as well as the clinical difficulties faced in patients with this rare anomaly.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131511057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Analysis of 65 Patients with Pancreatic Fistula and Wound Infection after Pancreatoduodenectomy (PD) with Duct-to-Mucosa Pancreaticojejunostomy: A Single-Center Report","authors":"M. Mazid","doi":"10.4172/2161-069X.1000481","DOIUrl":"https://doi.org/10.4172/2161-069X.1000481","url":null,"abstract":"Objective:The study sought to analyze Whipple procedure in 65 patients’ in-hospital evaluation of morbidity and mortality rate after pancreatoduodenectomy (PD) with adjusted duct-to mucosa pancreaticojejunostomy. Methods: A retrospective study of 65 consecutive patients that underwent (PD) at ‘The First Affiliated Hospital of Anhui Medical University teaching Hospital during the period of December 2008 to December 2015 was done. A two-layered duct-to-mucosa pancreaticojejunostomy over an internal transanastomotic stent was performed in all 65 patients. Results: The in-hospital morbidity and mortality rate in the study was 47.6% and 1.5%, respectively. One patient died as a consequence of mesenteric ischemia. Pancreatic fistula occurred in one patient (1.5%) and was treated conservatively with good results. The wound infection was the most common surgical complication (13/65; 20%) and occurred more often in patients who had a biliary stent inserted endoscopicallyprior to surgery (10/24; 41.7%), as compared to those without the stent (3/41; 7.3%; P<0.0001). Conclusions: The consequences of the present study recommend that a two-layered conduit to-mucosa pancreaticojejunostomy with inside trananastomotic stent is a sheltered anastomosis, connected with an okay of pancreatic fistula. The nearness of a biliary stent at the season of surgery speaks to a danger element for the improvement of postoperative injury contamination. In our information we have an aggregate number of 65 patients some of them we did endoscopy and some of them didn't. 24 patients were done endoscopy and in these cases 10 patients get wound contamination while 41 of our patients did not get endoscopy but rather 3 patients get wound disease. The summery of information is that the rate of wound contamination is high with patients is who get the endoscopy.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"4 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123269638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of Prognostic Scoring Systems in Turkish Alcoholic HepatitisPatients","authors":"F. Tekin, Z. Karasu, E. Erdogan, F. Gunsar, G. Ersoz, O. Ozutemiz, U. Akarca","doi":"10.4172/2161-069X.1000480","DOIUrl":"https://doi.org/10.4172/2161-069X.1000480","url":null,"abstract":"Objective: There is a lack of data concerning Turkish patients with alcoholic hepatitis (AH). The aims of the present study were to present the clinical characteristics of hospitalized AH patients and to compare the predictive ability of Maddrey’s discriminant function (DF) score, Model for End-Stage Liver Disease (MELD) score, Glasgow AH (GAHS) score and age, bilirubin, International Normalized Ratio (INR), and creatinine (ABIC) score on in-hospital mortality. \u0000Methods: The DF score and clinical data of 34 patients with AH admitted from 2008 to 2014 were reviewed from patient’s files. Scores for MELD, GAHS and ABIC were then retrospectively calculated. A comparison of scores was obtained using area under the receiver operating characteristics curves to predict in-hospital mortality. \u0000Results: In-hospital mortality was calculated at 23.5% (8/34). Treatment with corticosteroids and/or pentoxifylline was started in 18 patients with DF score ≥ 32; however, seven of them died (7/18, 39%). No significant differences were found between DF, MELD, GAHS and ABIC scores for predicting in-hospital mortality (p>0.05). \u0000Conclusion: DF score, which is easier and more practical, can be used in clinical practice to predict in-hospital mortality because other scores have no statistical superiority. The response to corticosteroid and/or pentoxifylline treatment in patients with a DF score ≥ 32 was poor in Turkish AH patients.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121249814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathological (Histological and Ultrastructural) Study in Stomach and Intestine ofHeteropneustes fossilis (Bloch) to Excel Mera 71, a Glyphosate-Based Herbicide","authors":"P. Samanta, Sandipan Pal, A. K. Mukherjee, A. Ghosh","doi":"10.4172/2161-069X.1000479","DOIUrl":"https://doi.org/10.4172/2161-069X.1000479","url":null,"abstract":"Effects of glyphosate-based commercial herbicide, Excel Mera 71 were performed to evaluate the pathological responses in stomach and intestine of Heteropneustes fossilis (Bloch) for duration of 30 days both under rice field and laboratory concentrations. Under light microscopy, stomach showed distortion in columnar epithelial cells (CEC), lamina propria (LP) and gastric glands under both conditions, but the severity of responses were more pronounced under laboratory condition. Severe fragmentation in mucosal folds (MF) and epithelial cells, and excessive mucus secretion were observed under scanning electron microscopic (SEM) study in laboratory study but alterations in stratified epithelial cells and microridges structure were not prominent under field; while deformation in mitochondria and endoplasmic reticulum and cytoplasmic vacuolations were seen under transmission electron microscopic (TEM) observation in both the conditions, but less severe in field study. Intestine showed distortion and fatty deposition in lamina propria, lifting of CEC and loss of brush border structures in laboratory study, while damage only at the tip of the mucosal villi and CEC were observed under field study through light microscopic observation. Under SEM study, degeneration in CEC and excessive mucus secretion over CEC were prominent, while under TEM study deformation and necrosis in mitochondria, severe cytoplasmic vacuolation, necrosis, cytosolic disorganization, and loss of cellular compartmentation were observed in laboratory study, but intestinal epithelium showed normal appearance under field observation. Therefore, present investigation depicted that long-term glyphosate exposure caused stronger pathological alterations under laboratory condition compared with field study and finally, displayed responses could be considered as indicators of herbicidal contamination in aquatic environment.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"32 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133769880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a Role of Lateral Pelvic Lymph Node Dissection in the Current Era of Neoadjuvant Chemoradiotherapy for Rectal Cancer","authors":"Girish K Kundagulwar, V. Pai, A. Saklani","doi":"10.4172/2161-069X.1000473","DOIUrl":"https://doi.org/10.4172/2161-069X.1000473","url":null,"abstract":"Colorectal cancer is the third most common cancer in men. Total mesorectal excision remains the gold standard treatment for rectal cancer with chemoradiotherapy preceding the surgery in all locally advanced rectal malignancies. Lateral pelvic lymph node dissection (LPLND), although a part of standard surgery for rectal cancers treatment in Japan has not been adopted by surgeons in the rest of the world. There is a long-standing controversy on whether lateral pelvic node metastasis represents localized or metastatic disease. Current standard in Japan is to consider lateral pelvic nodes as regional disease and, hence, perform prophylactic LPLND in low rectal cancers of stage T3 or more or with involved mesorectal nodes. In contrast, standard therapy in west is to consider lateral pelvic nodes as systemic disease and, hence, to either ignore them or treat obvious nodes with chemoradiotherapy. In Japan, neoadjuvant chemoradiotherapy (NACTRT) is less commonly used for locally advanced rectal cancers in contrast to the practice in the west. The role of LPLND in patients receiving NACTRT remains to be established. The aim of this article is to review the evidence for the role of LPLND in the current era of NACTRT.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125452260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}