Journal of Gastrointestinal and Digestive System最新文献

{"title":"Endoscopic Submucosal Dissection of Secondary Hypopharyngeal Neoplasia in Trismus Oral Cancer Patients: Case Series Report","authors":"C. Chung, Wu-Chia Lo, Kuan-Chih Chen, Li-Jen Liao","doi":"10.4172/2161-069X.1000507","DOIUrl":"https://doi.org/10.4172/2161-069X.1000507","url":null,"abstract":"The incidence of second primary tumor (SPT) in head and neck (H&N) cancer patients is not uncommon [1,2]. \u0000 When using image-enhanced endoscopy (IEE) screening in patients at risk, especially narrow-band imaging (NBI) \u0000 endoscopy and chromoendoscopy with Lugol's solution, approximately 20% of H&N cancer patients have \u0000 synchronous neoplasia in H&N regions of esophagus [1,2]. Unfortunately, some of them have trismus because of \u0000 oral submucosa fibrosis secondary to long-term betel quit chewing or post-irradiation therapy, and tumor-related \u0000 airway compromised. These situations make the pharyngeal passages difficult to reach with conventional \u0000 endoscopes. Traditionally, hypopharyngeal neoplasia in trismus patients are managed with widest field of resection, \u0000 open partial pharyngectomy and usually in conjunction with partial or total laryngectomy, which are accompanied \u0000 with poor quality of life (QoL). We present three trismus patients with early hypopharyngeal neoplasia treated by \u0000 transoral endoscopic submucosal dissection (ESD).","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"276 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127381474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of Reproductive Disorders Related to Celiac Disease Under Glutenfree Diet","authors":"A. Aomari, M. Firwana, A. Amjahdi, A. Rahaoui, I. Benelbarhdadi, F. Ajana","doi":"10.4172/2161-069X.1000506","DOIUrl":"https://doi.org/10.4172/2161-069X.1000506","url":null,"abstract":"Introduction: Celiac disease is an autoimmune enteropathy induced by the ingestion of gluten (wheat, barley, rye). The classical form has become a minority. Currently, the most frequent forms of presentation are extraintestinal with various manifestations, among others, reproductive disorders. The aim of our study is to assess the frequency of these disorders in celiac disease and their evolution under gluten-free diet. \u0000Materials and methods: Descriptive retrospective study of 173 patients with celiac disease followed in the department of diseases of the digestive tract \"Medecine C\" of the Ibn Sina Hospital in Rabat, over a period of 18 years. \u0000Result: In 173 patients with celiac disease, 58 patients (28.9%) had reproductive disorders. There are 53 women and 5 men. The average age was 25-32 years. The diagnosis of celiac disease is based on histology and serology. The reproductive problems were never isolated but always associated with other digestive or extra-intestinal signs at the time of diagnosis of celiac disease. These disorders are represented by: delayed puberty in 11 cases (19%), secondary amenorrhea in 13 cases (22.4%), irregular menstrual in 12 cases (20.6%), absence of development of secondary sex characteristics in 8 cases (12.5%), spontaneous abortions in 7 cases (10.9%), menometrorrhagia in 4 cases (13.8%), primary sterility in 5 cases (8.6%), early menopause in 6 cases (10.3%), premature delivery in 3 cases (5%), primary amenorrhea in 2 cases (3.4%) and intrauterine fetal death in one case (1.7%). All our patients have had a gluten-free diet. 15 patients lost to follow-up, two patients died and 12 patients undergoing follow-up. The remaining 29 patients, the evolution of reproductive disorders under gluten-free diet was favourable in 26 cases (90%), with the normalization of cycles in 15 cases, resumption of cycles in 6 cases, development of secondary sex characteristics in 2 cases, fertility resumption in one case, initiation of cycles after primary amenorrhea in one case and delivery of a new-born at term after premature deliveries in one case. The evolution was unfavourable in 3 cases with the notion of miscarriage 4 years after the start of the gluten-free diet in one patient and the absence of cycle resumption in two cases. \u0000Conclusion: The reproductive disorders associated with celiac disease are frequent and varied. In our study, these disorders responded very well under a gluten-free diet, conducted in 90% of cases. These disorders are thus reversible under this diet.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129773636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cocaine-induced Fulminant Hepatitis","authors":"A. Roqué, G. Soy, O. Retto, C. Núñez, E. Fort, X. Aldeguer, Piñol","doi":"10.4172/2161-069X.1000505","DOIUrl":"https://doi.org/10.4172/2161-069X.1000505","url":null,"abstract":"Cocaine abuse and intoxication is a global problem leading to many medical complications that can result in   significant morbidity and mortality. We present the clinical case of a young man who presented with a fulminant   hepatic failure, renal failure and a duodenal ulcer related to cocaine consumption.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129476273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution and Outcome of Eight Patients Undergoing Treatment of Gastroesophageal Disease by Esophyx","authors":"A. A. Abboud, W. Khalek","doi":"10.4172/2161-069X.1000504","DOIUrl":"https://doi.org/10.4172/2161-069X.1000504","url":null,"abstract":"Background: Gastroesophageal reflux disease (GERD) is arguably the most common disease encountered by \u0000 the gastroenterologist. It is mainly caused by defects in the lower esophageal sphincter (LES) that induces \u0000 spontaneous transient LES relaxations (tLESRs). This is a chronic condition with typical and atypical, sometimes \u0000 troublesome manifestations requiring long term treatment. Anti-reflux surgery is an alternative option. The TIF (transoral \u0000 incisionless fundoplication) procedure by offering some advantages over surgery could be recommended for \u0000 patients whose symptoms recur upon discontinuation of the medications. This study intended to assess the safety \u0000 and efficacy of TIF for treating GERD. \u0000Methods: A prospective trial was conducted at Lebanese Hospital Geitaoui University Medical Center and Middle \u0000 East Institute of Health in Lebanon, on 8 patients, age 28-55 years, with chronic GERD, symptoms (>5 years), \u0000 undergoing EsophyX procedure and followed for 1 year after their procedure. Information concerning the patients \u0000 was gathered using an international questionnaire (GERD-HRQL, Health Related Quality of Life questionnaire) filled \u0000 by the treating physician. \u0000Results: When compared to scores before TIF and without medications, the GERD-HRQL scores were \u0000 significantly reduced one year after the procedure. Regurgitation experienced was reduced to 62.5% compared to \u0000 75% while patients were off PPI. Symptoms free (GERD-HRQL score ≤ 12) achieving complete cessation of \u0000 medications, were reported by 25% of patients. Overall 37.5% of patients were satisfied, 12.5% neutral, and 50% \u0000 less satisfied with their results.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114686689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of the Patients Undergoing Colonoscopy in a Single Center within an 8-year Period","authors":"Aslan Ãelebi, F. Teker, Mujgan Gurler, D. Koc, A. Ozdemir, I. Ekizoğlu, M. Altay","doi":"10.4172/2161-069X.1000503","DOIUrl":"https://doi.org/10.4172/2161-069X.1000503","url":null,"abstract":"Aim: To evaluate patient characteristics by reviewing colonoscopy procedures performed within an 8-year period \u0000 in the endoscopy centre of a training and research hospital. \u0000Methods: Colonoscopy procedures that were performed for various indications between 2002 and 2009 in the \u0000 endoscopy unit of our hospital were retrospectively evaluated. Of 3035 colonoscopy procedures, 2831 were \u0000 included in the analysis. In addition to demographic characteristics of the patients, presence and localization of \u0000 colorectal masses, presence of inflammatory bowel disease, frequency of presence of hemorrhoids, diverticula, \u0000 polyps, and other diseases, as well as complications were recorded. \u0000Results: The mean age of the patients (male, 50.5%) was 54.36 ± 15.05 years (range, 16-93 years). While a \u0000 pathological finding was determined in 1512 (53.4%) colonoscopy procedures, 1319 (46.6%) colonoscopy \u0000 procedures were reported as normal. Concerning complications during examinations, perforation was encountered \u0000 in two patients and major bleeding was not determined in any of the patients. The most common diagnoses were \u0000 polyps (15.9%) and hemorrhoids (15.9%), followed by colorectal mass (12.9%), diverticula (6.8%), and inflammatory \u0000 bowel disease (5.6%). \u0000Conclusion: The fact that colorectal masses ranked third among the colonoscopic diagnoses suggested that \u0000 cancer screening programs should be handled nationally.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121932704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Cause of Intestinal Volvulus: Spontaneous Intramural Hematoma ofSmall Intestine","authors":"Y. E. Gamrani, Z. Chahbi, H. Qacif, S. Kaddouri, A. Badi, M. Zyani","doi":"10.4172/2161-069X.1000502","DOIUrl":"https://doi.org/10.4172/2161-069X.1000502","url":null,"abstract":"Introduction: Anticoagulation therapy is widely used for curative and prophylactic purposes. The most serious complication is bleeding, which presents as an intramural hematoma of the small intestine; however, it is uncommon, seen in 1 in 2,500 patients. We report an unusual case of a warfarin overdose that resulted in spontaneous intramural hematoma of the small intestine with intestinal volvulus. \u0000Observation: A 60-year-old patient was admitted to the emergency department with diffuse abdominal pain and anuria that had started several hours earlier. The patient had a long history of complicated diabetes, marked by moderate chronic renal failure as well as arterial hypertension and atrial fibrillation, which was managed with the oral anticoagulant acenocoumarol. Respiratory and cardiovascular exams revealed no abnormality except for an irregular rhythm in cardiac auscultation. His abdomen was mildly distended and there was tenderness with Blumberg’s sign in the periumbilical region, which was associated with signs of peritoneal irritation. Laboratory tests showed incoagulable plasma, an inflammatory syndrome, and renal failure. The Computed tomography (CT) scan without intravenous injection revealed a spontaneous intramural hematoma of the small intestine with intestinal volvulus; moderate hemoperitoneum was also documented. Initial patient management consisted of the cessation of oral anticoagulation therapy, gentle gastric aspiration, correction of the coagulopathy with fresh frozen plasma, and the administration of parenteral Vitamin K. The patient’s condition began to decline, marked by a worsening of clinical and laboratory parameters, and the patient ultimately died from acute cardio-circulatory failure while on ventricular fibrillation. \u0000Conclusion: Spontaneous small intestine hematoma is an uncommon clinical complication, but it should be taken into consideration for any patient on long-term anticoagulation therapy who presents with acute abdomen. Abdominal CT is the key for diagnosis. Early diagnosis is crucial because most patients can be treated nonoperatively with a good outcome.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117126111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Upper Gastrointestinal Bleeding from Gastric Involvement of Chronic Lymphocytic Leukemia: A Case Report","authors":"N. Than, M. Mottershead, G. Langman, A. Daley","doi":"10.4172/2161-069X.1000499","DOIUrl":"https://doi.org/10.4172/2161-069X.1000499","url":null,"abstract":"Gastrointestinal involvement of chronic lymphocytic leukaemia (CLL) is uncommon and acute GI bleeding as a result of CLL involvement is much rarer. We report a 77-year-old lady with known history of chronic lymphocytic leukaemia (CLL) presented to emergency department with haematemesis and melaena. Upper gastrointestinal endoscopy showed large necrotic looking area in the stomach with bleeding from necrotic area. Biopsies showed lymphoid infiltration and immunohistochemistry showed CD20+, CD5+, Cyclin D1- and CD23- which were similar findings to CLL from bone marrow biopsy.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"31 32","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131804684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombosed Cavo-Portal Hemi-Transposition Salvaged by Digital SubtractionAngiography and Self Expanding Metallic Stent Deployment-Report of FirstCase and Review of Literature","authors":"Selvakumar Naganathan, Subash Gupta, H. Rastogi","doi":"10.4172/2161-069X.1000500","DOIUrl":"https://doi.org/10.4172/2161-069X.1000500","url":null,"abstract":"Cavo Portal Hemi-Transposition (CPHT) is a surgical technique used in liver transplantation (LT) to salvage low portal perfusion situations. Although non physiological it is an established surgical technique for over two decades for the aforementioned clinical situation. CPHT also may fail. Our patient was a 6 months old male child with decompensated cirrhosis secondary to extra hepatic biliary atresia. Intraoperatively there was recurrent thrombosis of portal vein anastomosis. Hence portal flow of the graft was salvaged by CPHT. However, in the immediate postoperative period there was thrombosis of CPHT. Emergency angiography and stenting of CPHT was done. At 3 years post LT the child has stable graft function and good quality of life. This is the first case of this kind to be reported in the literature.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132457588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring Sentinel of Diarrhea: A Rotavirus in the Site of Hospital ComplexPediatrique of Kingasani II: 2009-2014","authors":"J. Mukwela, G. Kitambala, I. Baba, M. Kimbi, J. Emonmey, S. Clelia, D. Masungi, N. Kibaka, D. Disengomoka, Katembo, L. Bitaya, M. Mawonda, S. Lubi, J. Lupwenge, C. Belerheine, V. Masudi","doi":"10.4172/2161-069X.1000501","DOIUrl":"https://doi.org/10.4172/2161-069X.1000501","url":null,"abstract":"After paludism, respiratory infections, and meningitis, the severe diarrhoea belongs to the major causes of the problems of public health in the whole world. According to current statistics' of WHO, this disease cause at least 483 000 deaths of children from zero to 59 months per annum in the world. The children whose above mentioned age, are victims permanant of this very fatal disease. Let us announce by here that the vaccine against the gastro enterite with rotavirus is already operational in certain developed countries whose principal objective remains that to reduce its incidence. In addition, no one is not unaware of that the diarrhoea with rotavirus remains one of the concerns paramount among the problems of public health in the countries under developed and sends development; they is the cases in particular of the Latin America and certain sub-Saharan countries of Africa. At strong present remains to draw the alarm bell near the authorities politico medical and administrative on all the levels in order to make a plea with close to the backers for establishment again vaccine with rotavirus especially in the countries with strong incidence of this cruel disease (case of the RDC). This would reduce the incidence. By way of recall, it ya place to announce by here that it is since 2009 that the ministry for the public health of the RDC, via its program widened of vaccination (PEV) with the support of the certain partners and financial backers of the bottom had made the installation of a study on the incidence of this disease.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131942082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of Smart Shooterî for Colorectal Endoscopic Submucosal Dissection","authors":"D. Kikuchi, T. Iizuka, S. Hoteya, M. Kaise","doi":"10.4172/2161-069X.1000497","DOIUrl":"https://doi.org/10.4172/2161-069X.1000497","url":null,"abstract":"Objectives: For safe and speedy colorectal endoscopic submucosal dissection (ESD), it is desirable that the endoscopist operates the endoscope and treatment device simultaneously. We developed a new device, named Smart Shooter® (SS), and introduced it for colorectal ESD. Methods: SS is a loop-shaped channel extender that allows the endoscopist to operate the endoscope with the right hand while manipulating a treatment device with the right thumb. During a 1-year period after introduction of SS, colorectal ESD using SS was performed on 13 consecutive patients by a single endoscopist. The outcome of these patients were compared with that of 13 consecutive patients treated by the conventional technique before introduction of SS, with respect to treatment-related factors. Results: All patients in the SS and conventional groups were treated by en bloc resection, with no serious complications. The use of SS reduced the procedure time from 84.1 to 67.5 min and improved the dissection speed from 16.4 to 20.7 mm2/min, although. Before introduction of SS the clinical path was adhered to by 61.5% (8/13) patients. After introduction all patients (13/13) adhered to the clinical path. Conclusion: SS may contribute to safe and speedy colorectal ESD.","PeriodicalId":388922,"journal":{"name":"Journal of Gastrointestinal and Digestive System","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121116314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}