Ceska a Slovenska Farmacie最新文献_第8页

Evaluation of polycystic ovary syndrome pharmacotherapy. 多囊卵巢综合征药物治疗的评价。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.031

Mária Kolesárová, Nikola Zálešová, Dana Marcinčáková, Kolesár Dalibor, Zuzana Mačeková

{"title":"Evaluation of polycystic ovary syndrome pharmacotherapy.","authors":"Mária Kolesárová, Nikola Zálešová, Dana Marcinčáková, Kolesár Dalibor, Zuzana Mačeková","doi":"10.36290/csf.2024.031","DOIUrl":"10.36290/csf.2024.031","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects approximately 5-10 % of women of reproductive age. PCOS can have a significant impact on the quality of life of affected women, contributing to fertility problems and increasing the risk of metabolic and cardiovascular diseases. The aim of this study was to compare and evaluate the effectiveness of indicated 6-month pharmacotherapy in patients with PCOS. Data were collected from the medical records of patients in the gynecological outpatient clinic in Stara Lubovna. A total of 980 patients were enrolled in the study, of which 40 (4 %) were diagnosed with PCOS. At the beginning of the study, the patients were divided into three groups based on the main goal of therapy. The first group consisted of patients aged between 18 and 24 years for whom the primary therapeutic goal was the treatment of menstrual cycle disorders and the treatment of acne (N=13). The second group consisted of patients aged 25 to 35 years who were planning to become pregnant and the therapy was aimed at treating infertility (N= 19). The third group consisted of patients aged 36 years and older who already had a personal history of pregnancy, were not planning another pregnancy, and the therapy was focused on the comprehensive treatment of metabolic syndrome and alopecia (N= 8). To evaluate the effectiveness of the treatment, the mean values of Body Mass Index (BMI) and hormonal profile of the patients were compared by paired t-test (GraphPad Prism 8.3.0), before the start of pharmacotherapy and after 6 months of treatment. Results were considered statistically significant at p < 0.05. Our results confirm the success and efficacy of the indicated pharmacotherapy in all three groups. The selected pharmacotherapy contributed to the modification of the hormonal profile of the patients. The results suggest that PCOS therapy requires complex pharmacotherapy, individual approach and high adherence rate of patients.","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 E3","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel pyrazole bearing heterocyclic hybrids as promising biologically active compounds. 新型吡唑类杂环杂化物具有良好的生物活性。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.032

Kostiantyn Shabelnyk, Yevhen Zaika, Dmytro Skoryna, Inna Nosulenko, Anna Kinichenko, Oleksii Voskoboinik, Serhii Kovalenko

引用次数: 0

Oral supplementation of sodium, potassium and phosphate ions in extemporaneous preparation. 即席制剂中钠、钾、磷离子的口服补充。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.006

Markéta Petrželová, Jana Hénková

引用次数: 0

Pharmaceutical care for patients with acne. 痤疮患者的药学护理。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.023

Tereza Toušková, Kateřina Malá-Ládová

{"title":"Pharmaceutical care for patients with acne.","authors":"Tereza Toušková, Kateřina Malá-Ládová","doi":"10.36290/csf.2024.023","DOIUrl":"10.36290/csf.2024.023","url":null,"abstract":"Pharmaceutical care for patients with acne Acne is a multifactorial inflammatory skin disease affecting mostly adolescents, but it can persist into adulthood. The aim of treatment is to improve the patient's dermatological condition and improve the overall quality of life. Pharmacists play a very important role in the care of acne patients and this article reviews opportunities for pharmaceutical care of such patients. Pharmacists can identify patients with different forms of acne, engage in acne prevention including lifestyle modifications, and contribute to optimizing the choice and use of appropriate pharmacotherapy accompanied by non-pharmacological approaches according to the specific patient characteristics. The mainstay of acne treatment is topical pharmacotherapy, where over-the-counter products containing benzoyl peroxide or azelaic acid may be recommended for mild to moderate forms of acne. Retinoids or their combination with antibiotics are prescribed for moderate and severe forms of acne. When topical treatment is ineffective or resistant, systemic treatment including for example oral antibiotics or isotretinoin is considered. Pharmacists thus engage themselves in maximizing the effect and minimizing the risks of these drugs and, last but not least, educating patients on how to properly care for their skin using so called dermocosmetics, which is defined in this article.","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 3","pages":"148-155"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive therapy of upper functional dyspepsia: the potential of herbal medicines. 上肢功能性消化不良的综合治疗：草药的潜力。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.012

Vilma Vranová

引用次数: 0

Current pharmacotherapy of rosacea. 目前酒渣鼻的药物治疗。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.024

Magdalena Ryšavá, Renata Žáková

引用次数: 0

Enhancing pharmacovigilance practices: Insights from audits and ethical connotations. 加强药物警戒实践：从审计和伦理内涵的见解。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.033

Anetta Jedličková

{"title":"Enhancing pharmacovigilance practices: Insights from audits and ethical connotations.","authors":"Anetta Jedličková","doi":"10.36290/csf.2024.033","DOIUrl":"10.36290/csf.2024.033","url":null,"abstract":"Pharmacovigilance, pivotal in ensuring drug safety and regulatory compliance, requires meticulous surveillance and adherence to ethical standards. This article explores the multifaceted realm of pharmacovigilance, emphasizing the essential role of pharmacovigilance audits and compliance monitoring. By delving into key areas such as drug safety surveillance, signal detection, literature monitoring, and ethical considerations, this research sheds light on critical aspects of pharmacovigilance activities. The paper examines the outcomes of pharmacovigilance audits, highlighting common findings and areas for improvement to enhance regulatory compliance and the safety of pharmaceutical products. Insights gleaned from real-world experiences and regulatory guidelines underscore the importance of fostering a culture of good practice and ethical conduct in pharmacovigilance activities. By addressing challenges and trends, and elucidating the critical interaction between regulatory compliance, signal detection, and ethical considerations, this article provides valuable insights for stakeholders in the pharmaceutical industry, aiding them in optimizing pharmacovigilance systems and safeguarding patient safety.","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 E3","pages":"13-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation tools used for assessing inhalation technique in patients with chronic obstructive lung disease - a literature review. 用于评估慢性阻塞性肺疾病患者吸入技术的评估工具-文献综述

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.037

Gabriela Strnadová, Tereza Hendrychová, Vladimír Koblížek, Vratislav Sedlák, Josef Malý

{"title":"Evaluation tools used for assessing inhalation technique in patients with chronic obstructive lung disease - a literature review.","authors":"Gabriela Strnadová, Tereza Hendrychová, Vladimír Koblížek, Vratislav Sedlák, Josef Malý","doi":"10.36290/csf.2024.037","DOIUrl":"10.36290/csf.2024.037","url":null,"abstract":"Introduction and aim: Chronic obstructive lung diseases, including bronchial asthma and chronic obstructive pulmonary disease, among others, are characterized by inadequate adherence to inhalation technique. Evaluation of inhalation technique and subsequent repeated patient's education should be a routine part of therapy management. The aim of this article was to provide an overview of tools used to assess inhalation technique in patients with chronic obstructive lung disease based on a literature search and to analyse in more detail individual questionnaires/checklists specific for a group of inhalers or for a particular type of inhaler.Methods: Bibliographic database PubMed was used for the literature review. Original papers in Czech, English, German and French published in the period 2014-2023 focusing on assessing inhalation technique in patients with chronic obstructive lung disease were included.Results: The inclusion criteria were met by 66 studies, of which 49 studies assessed inhalation technique using individual questionnaires/checklists, 10 studies using electronic monitoring devices, 7 studies using the TAI-12 (Test of the Adherence to Inhalers) and 1 study using Vitalograph AIMTM (Aerosol Inhalation Monitor). In some works, a combination of the above methods was used.Conclusion: The use of individual questionnaires/checklists, whose reproducibility is limited due to their heterogeneity and inconsistent terminology, dominated the evaluation of inhalation technique. There is a need to introduce a simple validated tool applicable to all types of inhalation systems to unify the assessment of inhalation technique in research and clinical practice.","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 E4","pages":"9-33"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146041637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paratext in Antidotarium Cassoviense (1732). 《卡索维安论》（1732年）附文。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01 DOI: 10.36290/csf.2024.018

František Šimon

引用次数: 0

Analysis of medication administration in relation to food and beverages in inpatients. 分析住院病人用药与食物和饮料的关系。

Ceska a Slovenska Farmacie Pub Date : 2024-01-01

Ondřej Tesař, Josef Malý, Lucie Malečová, Kateřina Malá-Ládová, Martin Doseděl, Iva Brabcová, Martin Červený, Radka Prokešová, Hana Hajduchová, Ivana Chloubová, Valérie Tóthová, Jiří Vlček

{"title":"Analysis of medication administration in relation to food and beverages in inpatients.","authors":"Ondřej Tesař, Josef Malý, Lucie Malečová, Kateřina Malá-Ládová, Martin Doseděl, Iva Brabcová, Martin Červený, Radka Prokešová, Hana Hajduchová, Ivana Chloubová, Valérie Tóthová, Jiří Vlček","doi":"","DOIUrl":"","url":null,"abstract":"Proper medication administration in relation to beverage or food is one of the essential tools to achieve the pharmacotherapy goals. It is not known whether this is also considered in the care of inpatients. The aim of this study was to describe and analyse the current practice of medication administration in relation to food and beverages to patients hospitalized in four hospitals in the Czech Republic. This study was conducted based on the results of the first phase of a prospective observation study focused on the safety of medication administration performed by nurses. All data, including the timing of medication administration in relation to food and the data on beverages used, were obtained by the method of direct observation. The team of observersaccompanied the nurse during medication administration. The appropriateness of the medication administration in relationto food/beverages was assessed according to the summary of product characteristics and the published literature. In total, the administration of 5718 oral medications and 198 insulins were analysed. Unproper food timing wasobserved in 15.7% of oral medication administrations and 26.8% of insulin administrations. The highest number ofunproper food timing occurred in the proton pump inhibitors, antihypertensives, and prokinetics. Tea (63.4%) was the most used beverage. Errors with clinically serious impact have been observed in some groups of drugs. The necessity of a systemic approach in management of medication administration is required including interdisciplinary cooperation.","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"72 6","pages":"303-310"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0