Ceska a Slovenska Farmacie最新文献

{"title":"Rosemary - its biologically active compounds and their pharmacological effects.","authors":"Jana Karlíčková, Aneta Klížová","doi":"10.36290/csf.2024.008","DOIUrl":"https://doi.org/10.36290/csf.2024.008","url":null,"abstract":"<p><p>Rosemary - its biologically active compounds and their pharmacological effects Rosemary (Rosmarinus officinalis L.) has been used since ancient times for medicinal, cultic, and magic purposes. With the stress and diseases, it is increasingly popular today for many uses in both pharmacy and aromatherapy, as a spice in the kitchen and as a preservative. This plant has many interesting compounds (e.g. rosmarinic and carnosic acid, carnosol), which show a considerable amount of positive pharmacological effects.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"1,8-cineole (eucalyptol) in a therapy of respiratory diseases.","authors":"Zdeňka Navrátilová","doi":"10.36290/csf.2024.028","DOIUrl":"https://doi.org/10.36290/csf.2024.028","url":null,"abstract":"<p><p>1,8-cineole (eucalyptol) in a therapy of respiratory diseases 1,8-cineole (eucalyptol) is a natural terpenic compound isolated from eucalyptus essential oil, it is present also in other plant species, especially from Lamiaceae, Myrtaceae, and Zingiberaceae family. Plants containing 1,8-cineole have long been used to treat common cold and other respiratory diseases, gastrointestinal complaints, fever, infections, asthma, rheumatism, and skin conditions. 1,8-cineole is used in foods, cosmetics, perfumery, and also in pharmaceutical industry. 1,8-cineole exerts an antimicrobial, antiviral, mucolytic, anti-inflammatory and bronchodilatory effect and is suitable for the treatment of respiratory infections and other diseases. Medicinal effects were confirmed not only in vitro and in animal studies, but also in clinical trials. Medicinal products and dietary supplements containing 1,8-cineole are available.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 3","pages":"181-186"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rhinitis and Allergic Rhinitis - self-medication options.","authors":"Žaneta Tomčalová","doi":"10.36290/csf.2024.010","DOIUrl":"https://doi.org/10.36290/csf.2024.010","url":null,"abstract":"<p><p>Rhinitis and Allergic Rhinitis - self-medication options Rhinitis is one of the common diseases that the patient often does not consider necessary to consult a doctor and turns directly to the pharmacist in the pharmacy, who is usually much more accessible to him. It is definitely not appropriate to consider the rhinitis. The pharmacist's role in self-medication therefore consists in trying to determine from the patient's description of his troubles what type of rhinitis it may be, to assess the degree of severity and to decide on the necessity of intervention by a doctor, or the recommendation of a therapeutic procedure with over-the-counter medicinal products. In the case of self-medication, choose the most suitable product with maximum effect and minimum risk and explain the correct handling of it.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"58-65"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New edition of the Czech Pharmacopoeia 2023 and what preceded it.","authors":"Hana Bízková","doi":"10.36290/csf.2024.007","DOIUrl":"10.36290/csf.2024.007","url":null,"abstract":"<p><p>The Czech Pharmacopoeia 2023, according to which it is mandatory to proceed from 1.12.2023, is prepared according to the new waiver concept.The change concerns only the Special Part of the European Part of the ČL, which is translated and published only selectively starting from the 2023 ČL.The selection of the articles was made by the Pharmacopoeia Commission of the Ministry of Health in cooperation with experts.The General Part of the European Part of the PRC and the National Part of the PRC are published in full.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"39-41"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute intoxications with medications in children and the role of pharmacist in the National toxicological information center.","authors":"Erik Puchoň, Blažena Cagáňová, Silvia Plačková","doi":"10.36290/csf.2024.027","DOIUrl":"https://doi.org/10.36290/csf.2024.027","url":null,"abstract":"<p><p>Acute intoxications with medications in children and the role of pharmacist in the National toxicological information center National Toxicological Information Center (NTIC) provides 24 hours telephone consultation service in acute intoxications for physicians, health care providers and general public. More than half of all consulted intoxications provided by NTIC belong to the group of children younger than 18 years old.  Children 3 years old and younger were the main group of consulted intoxications in all children. Intoxications in children with the age up to 5 years old are often accidental intoxications without any or only mild symptoms. Older children and adolescents are more often consulted due to the suicidal attempt with moderate or severe symptoms. Chemicals, medications and plants were the most often consulted in children aged up to 18-years old during period 2018-2022. Pharmacist has complex knowledge of various scientific disciplines.  Pharmacist is valuable health care provider in NTIC as well as in various sectors of health care in society.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 3","pages":"176-179"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Travellers' diarrhoea - what to advise at a pharmacy currently?","authors":"Markéta Olšovská","doi":"10.36290/csf.2024.016","DOIUrl":"https://doi.org/10.36290/csf.2024.016","url":null,"abstract":"<p><p>Travellers' diarrhoea - what to advise at a pharmacy currently? Traveling abroad carries the risk of traveler's diarrhea, which affects 20 to 50% of individuals. This article focuses on the definition, classification, epidemiology, etiology, prevention, and treatment management of traveler's diarrhea. It also describes recommendations for patients traveling to higher-risk areas, which can be used by pharmacists in counceling activities in the pharmacy.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 2","pages":"113-117"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunctive treatment of behavioral disorders in patients with cognitive deficit.","authors":"Ivana Tašková","doi":"10.36290/csf.2024.043","DOIUrl":"https://doi.org/10.36290/csf.2024.043","url":null,"abstract":"<p><p>Adjunctive treatment of behavioral disorders in patients with cognitive deficit The article provides an overview of the pharmacotherapy of behavioural and psychological symptoms of dementia (BPSD) in the context of evidence-based medicine. Its goal is to provide readers with a practical and educational overview of managing these symptoms. Cognitive disorders, including dementia, result from the disruption of higher cortical functions of the brain. Dementia often manifests not only through cognitive dysfunction but also through BPSD, such as agitation, aggression, anxiety, psychosis, and sleep disturbances. These symptoms affect up to 97% of patients with dementia and significantly reduce the quality of life for both patients and caregivers. BPSD are often more stressful for patients and caregivers than the cognitive symptoms themselves. Behavioural symptoms include a wide range of manifestations from non-aggressive forms such as pacing and repetitive movements to aggressive and agitated behaviour (verbal and physical). Psychological symptoms can include depression, anxiety, and psychotic symptoms such as paranoia and delusions. The causes of BPSD can be varied, as well as their risk factors (including e.g. co-medication, comorbidities, the patient's personality traits, inappropriate communication by caregivers, and environmental influences). The pharmacotherapy of BPSD is complex and often involves the use of antipsychotics, antidepressants, benzodiazepines, or acetylcholinesterase inhibitors and memantine. Due to the diversity of manifestations and causes of BPSD, a unified pharmacotherapeutic approach cannot be applied. Non-pharmacological approaches should always be preferred, except in cases of severe depression, psychosis, or aggression that may endanger the patient or someone else. In practice, many medications indicated for BPSD therapy are used off-label. The pharmacotherapy of BPSD should only begin after ruling out other causes of BPSD. Furthermore, it should only be initiated after considering all risks and potential benefits, starting with low geriatric doses, monitoring side effects, regularly reassessing effectiveness, and administering medications for the shortest possible duration should be also applied.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 4","pages":"245-250"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daprodustat: a new approach to the treatment of anemia in chronic kidney disease.","authors":"Viktória Paulusová, Pavel Ryšánek, Martin Šíma, Ondřej Slanař","doi":"10.36290/csf.2024.013","DOIUrl":"https://doi.org/10.36290/csf.2024.013","url":null,"abstract":"<p><p>Daprodustat: a new approach to the treatment of anemia in chronic kidney disease Daprodustat, also known under the trade name DUVROQ, is a small molecule developed by GlaxoSmithKline, which has become a promising drug in the field of anemia treatment in patients with chronic kidney disease. Daprodustat belongs to a group of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors. These drugs interfere with the regulation of erythropoietin, which is a key factor in the production of red blood cells. This drug was approved in Japan in June 2020 and clinical studies with it are ongoing in several countries around the world, where they focus on evaluating the effectiveness and safety in various populations of patients with chronic kidney disease.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 2","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of gastrointestinal side effects of cancer pharmacotherapy: Part 1: Diarrhoea, constipation, mucositis and anorexia.","authors":"Jan Juřica, Miroslav Turjap","doi":"10.36290/csf.2024.040","DOIUrl":"https://doi.org/10.36290/csf.2024.040","url":null,"abstract":"<p><p>Management of gastrointestinal side effects of cancer pharmacotherapy: Part 1: Diarrhoea, constipation, mucositis and anorexia Gastrointestinal side effects are common in cancer pharmacotherapy and may be facilitated by the disease itself. These adverse effects lead to reduced quality of life and may result in premature termination of therapy, which can adversely affect treatment outcomes. In extreme cases, adverse effects can even lead to patient death. This article reviews the main gastrointestinal side effects of anticancer drug therapy anticancer drug therapy in the context of solid tumor treatment and discusses the appropriate management and discusses the appropriate management of these complications. In the first part of this two-part article, we discuss diarrhoea, constipation, mucositis and anorexia.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 4","pages":"222-227"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological profile of erdosteine - known molecule - new effects.","authors":"Hana Kotolová, Martina Nováková","doi":"10.36290/csf.2024.003","DOIUrl":"https://doi.org/10.36290/csf.2024.003","url":null,"abstract":"<p><p>Erdostein belongs to the well-known thiol mucoactive drugs, whose effect is used in respiratory infections. Recently, expert findings show that the effect of erdosteine is more complex and can significantly contribute to the management of respiratory infections. Its antioxidant and anti-inflammatory properties come to the fore, or antiviral properties associated with them, as well as the ability to reduce bacterial adhesion and increase the effects of some antibiotics. Erdostein represents a comprehensive therapeutic option both in the field of self-treatment of respiratory infections and in other respiratory diseases.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}