Ceska a Slovenska Farmacie最新文献

{"title":"Paratext in Antidotarium Cassoviense (1732).","authors":"František Šimon","doi":"10.36290/csf.2024.018","DOIUrl":"https://doi.org/10.36290/csf.2024.018","url":null,"abstract":"<p><p>Paratext in Antidotarium Cassoviense (1732) In 1732, a work known as Antidotarium Cassoviense was published in Košice, which represents the first attempt at a pharmacopoeia in the territory of Hungarian kingdom. It is very brief, with 28 pages in quarto format. The paper deals with the paratext of the Košice Antidotarium. It contains a translation of all its parts from Latin into Slovak as well as a commentary on them. The parts of the paratext are the title page, the preface, the appendix, the approval of the doctors and the colophon. The preface names two reasons for the publication, one, to try to restore the reputation of the city pharmacy, the other, to help the health of the reader, the city of Košice and the whole Upper Hungary. The paratext mentions three times the removal of old, ineffective medicines, which were even burned in public. The author of the text, the provisor Thaurenti, begs the reader to trust this work and invites him to cooperate.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 2","pages":"124-128"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Available diagnostic tests in the pharmacy and the role of the pharmacist.","authors":"Eliška Kolmanová, Ondřej Tesař","doi":"10.36290/csf.2024.030","DOIUrl":"https://doi.org/10.36290/csf.2024.030","url":null,"abstract":"<p><p>Available diagnostic tests in the pharmacy and the role of the pharmacist The topic of in vitro diagnostic tests is a relatively robust area of medical devices. It includes tests used in the providing of healthcare, i.e., intended for healthcare professionals, and a group of tests intended directly for consumers (Direct-To-Consumer tests). The subject of the following article is diagnostic tests intended for home in vitro self-testing of patients in the Czech Republic. The aim is to present a basic overview of the available tests, to present the principle of diagnostic tests and in selected groups of tests to summarise the most important information for the correct performance of tests that should be part of pharmaceutical care.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 3","pages":"193-198"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical devices in wound healing V: Special types of wound plasters II.","authors":"Barbora Vraníková, Andrej Kováčik","doi":"10.36290/csf.2024.045","DOIUrl":"https://doi.org/10.36290/csf.2024.045","url":null,"abstract":"<p><p>Medical devices in wound healing V: Special types of wound plasters II Patches represent a broad category of medical devices with versatile applications that go far beyond their traditional function as wound dressings. This article focuses on the other possible utilization of patches, such as fixation patches for cannulas, patches for epicutaneous tests, warming and cooling patches, patches for acne, anti-snoring patches, and mosquito-repellent patches. In addition to their specific functions, the article highlights the importance of correct application, which represents crucial knowledge not only for pharmacists and pharmacy assistants but also for other healthcare professionals who work with these patches in practice.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 4","pages":"261-264"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-related hospitalizations - insights from the Czech Republic.","authors":"Zuzana Juhásová, Martina Maříková, Jiří Vlček","doi":"10.36290/csf.2024.015","DOIUrl":"https://doi.org/10.36290/csf.2024.015","url":null,"abstract":"<p><p>Drug-related hospitalizations - insights from the Czech Republic Background and objective: Drug-related hospitalizations represent a significant burden on healthcare. The aim of the study was to determine the prevalence of drug-related hospitalizations and identify medications and clinical manifestations associated with drug-related hospitalizations in patients admitted to hospital through the emergency department.</p><p><strong>Methods: </strong>This cross-sectional study examined unplanned hospitalizations at the University Hospital Hradec Kralove through the Department of Emergency Medicine between August and November 2018. Data were obtained from electronic health records. The methodology for identifying drug-related hospitalizations was based on the guideline of the European project OPERAM. This article focuses on a subgroup of drug-related problems related to the medication safety.</p><p><strong>Results: </strong>Of the total 1252 hospitalizations analyzed, 145 cases were identified as drug-related. The prevalence of drug-related hospitalizations was 12% (95% confidence interval 10-13). In 62% of cases, medications only contributed to the cause of hospitalization. Antithrombotics, cytostatics, diuretics, and systemic corticosteroids were the most common medication classes leading to drug-related hospitalizations. Gastrointestinal bleeding was the most common cause of drug-related hospitalizations. The potential preventability of drug-related hospitalizations was 34%.</p><p><strong>Conclusion: </strong>Drug-related hospitalizations remain relatively common, while some of them could be potentially prevented. Pharmacists can contribute to enhancing patient safety by detecting drug-related problems and proposing measures to minimize risks.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 2","pages":"93-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic spontaneous urticaria, treatment with antihistamines.","authors":"Iva Karlová","doi":"10.36290/csf.2024.002","DOIUrl":"https://doi.org/10.36290/csf.2024.002","url":null,"abstract":"<p><p>Chronic spontaneous urticaria is characterized by reccurent wheals lasting more than 6 weeks, it can persist for months or years. The disease can lead to a significant worsening in the quality of life. According to recent guidelines second-generation non-sedative antihistamines are the first-line treatment. If the therapeutic effect of the standard dose of antihistamines is insufficient, it is recommended to up-dose to 4-fold.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"13-15"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical care in the self-treatment of common urological problems.","authors":"Jana Šolínová","doi":"10.36290/csf.2024.009","DOIUrl":"https://doi.org/10.36290/csf.2024.009","url":null,"abstract":"<p><p>Pharmaceutical care in the self-treatment of common urological problems In case of self-treatment of common urological disorders, a pharmacist or pharmacy assistant is often the first healthcare professional the patient turns to. Appropriate information should be obtained from the interview with the patient to distinguish between symptoms and conditions suitable for self-treatment and, conversely, to recommend a visit to the physician. The first contact of a patient with healthcare professionals in a pharmacy can also contribute to the detection of more serious diseases. The article deals with the possibilities of pharmaceutical care for a patient with common urological difficulties and the requirement of a recommendation for self-treatment, focusing on the understanding of individual symptoms, their differentiation, principles of self-treatment and the identification of situations unsuitable for self-treatment.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"48-56"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New approaches to the issue of pyrogens in parenteral preparations.","authors":"Michal Janů","doi":"10.36290/csf.2024.026","DOIUrl":"https://doi.org/10.36290/csf.2024.026","url":null,"abstract":"<p><p>New approaches to the issue of pyrogens in parenteral preparations The article provides a basic understanding of the pathophysiology of exogenous and endogenous pyrogens, particularly in the context of parenteral administration of drugs and the use of medical devices. It explains that pyrogens cause an increase in body temperature by activating the thermoregulatory center in the hypothalamus, with bacterial lipopolysaccharides being the most common source of pyrogenic burden. Contamination of pharmaceuticals with pyrogenic substances can lead to adverse effects, including life-threatening conditions. The text focuses on modern methods for identifying pyrogens, specifically endotoxins, and selecting suitable analytical procedures for their determination. These include in vivo tests on rabbits and the bacterial endotoxin tests, as well as in vitro tests such as the monocyte activation test and the recombinant Factor C test. The work includes a detailed description how to perform these tests, their advantages and disadvantages, and the development of methods for detecting pyrogens in pharmaceuticals. The author explains the reasons of false positive and negative test results, and ilusrates the calculations of threshold endotoxin limits. Information is provided on the new strategy of the European and Czech Pharmacopoeias on this issue, emphasizing efforts to reduce pyrogenic burden and the need to control both microbiological and endotoxin contamination levels.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 3","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical care for patients with sore throat not requiring medical attention.","authors":"Lenka Ťupová, Tereza Hendrychová, Josef Malý","doi":"10.36290/csf.2024.044","DOIUrl":"https://doi.org/10.36290/csf.2024.044","url":null,"abstract":"<p><p>Pharmaceutical care for patients with sore throat not requiring medical attention Counsultancy in self-treatment of mild health problems is one of the dominant aspects of providing pharmaceutical care, especially in pharmacy practice. A sore throat is one of the most common reasons for visiting a pharmacy. According to current knowledge, the biggest pitfall of sore throat management is the systematic and reliable classification of patients into uncomplicated and potentially complicated cases, which should ideally take place at the level of pre-medical care, i.e. in a pharmacy. For this purpose, the practical use of the self-treatment algorithm in the therapy of sore throat was presented in the article. The introduction of a systematic algorithm into pharmacy practice could contribute to higher efficacy of the provided care and reduce the risk of overlooking warning symptoms (red flags). The article also provides an overview of over the counter therapeutic options for sore throat.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 4","pages":"252-260"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obsolete for many years but still in use - consumption of phenobarbital in compounding pharmacies.","authors":"Miroslav Turjap, Eva Pailová, Jan Juřica","doi":"10.36290/csf.2024.001","DOIUrl":"https://doi.org/10.36290/csf.2024.001","url":null,"abstract":"<p><p>Phenobarbital was synthesized by the German organic chemist Emil Fischer in 1911. It is approved and marketed in the Czech Republic as an antiepileptic in tablet and injection form. Although phenobarbital as a hypnosedative has been outdated for decades, it is still available as a substance and used for the individual compounding of various obsolete mixtures. It is likely that prescribers are unaware of the risks associated with their use. The article presents a brief pharmacological profile of phenobarbital, lists the most often used mixtures, substance consumption and risks associated with its use.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct oral anticoagulants from the perspective of Czech pharmacists - opinions, attitudes, confidence, and patient education during dispensing in a pharmacy.","authors":"Simona Dvořáčková, Kateřina Malá-Ládová, Tereza Mertová, Eliška Kolmanová, Josef Malý","doi":"10.36290/csf.2024.004","DOIUrl":"https://doi.org/10.36290/csf.2024.004","url":null,"abstract":"<p><p>Direct oral anticoagulants from the perspective of Czech pharmacists - opinions, attitudes, confidence, and patient education during dispensing in a pharmacy Introduction and Aim: Pharmacists play an important role in the management of anticoagulation therapy, therefore good knowledge and confidence in care of patients treated with anticoagulation are essential. The aim of this study was to analyse the opinions and attitudes of pharmacists in the Czech Republic towards direct oral anticoagulants (DOACs), their perception of the benefits and risks of DOACs, and the position of pharmacists in educating patients about the basic principles of DOAC treatment in the context of dispensing these medicines in pharmacies.</p><p><strong>Methods: </strong>An online anonymous questionnaire survey conducted in 2021 among pharmacists of three specific District Pharmacists Associations of the Czech Chamber of Pharmacy. The questionnaire included 32 open- and closed-ended questions, and questions for reporting of the level of agreement using a Likert scale. Descriptive statistics, parametric and non-parametric tests were used to evaluate the data.</p><p><strong>Results: </strong>A total of 162 pharmacists participated (14% return rate), 139 of whom dispensed medicines in a pharmacy in the last year. Respondents working in pharmacies located in any health centre and in hospital pharmacies reported dispensing DOACs more frequently (p &lt; 0.001). The majority of respondents (73%) felt completely or rather confident in providing expert information regarding DOACs. Higher confidence was associated with respondents working in hospital pharmacies or pharmacies located in health centres (p &lt; 0.05), working in clinical pharmacy wards (p &lt; 0.05) and being more likely to dispense DOACs in the pharmacy (p &lt; 0.001). Higher confidence was related to the areas pharmacists discussed with patients during DOAC dispensing, e.g., reasons for using DOACs or how to administer.</p><p><strong>Conclusion: </strong>The frequency of dispensing DOACs, type of pharmacy, and working as clinical pharmacist influenced respondents' confidence towards DOACs. Confidence may have influenced the course of DOAC dispensing in the pharmacy. Consolidating the pharmacist's position in patient education during DOAC treatment and strengthening pharmacists' confidence in dispensing DOACs should be therefore considered.</p>","PeriodicalId":38771,"journal":{"name":"Ceska a Slovenska Farmacie","volume":"73 1","pages":"22-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}