中华心血管病杂志最新文献

{"title":"[Using intravascular imaging to guide percutaneous coronary intervention].","authors":"N Guo, Z Y Yuan","doi":"10.3760/cma.j.cn112148-20260315-00169","DOIUrl":"10.3760/cma.j.cn112148-20260315-00169","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"493-497"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Extreme high temperature and cardiovascular disease: mechanisms, burden, and response strategies].","authors":"L Zhou, X T Song","doi":"10.3760/cma.j.cn112148-20260125-00062","DOIUrl":"10.3760/cma.j.cn112148-20260125-00062","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"585-589"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Feasibility and safety of leadless pacemaker implantation in elderly patients].","authors":"J J Wang, F Ze, X B Li, D Li, X Zhou, J B Duan, C C Wu, J S He, L Wang, C Z Yuan","doi":"10.3760/cma.j.cn112148-20260305-00138","DOIUrl":"10.3760/cma.j.cn112148-20260305-00138","url":null,"abstract":"<p><p><b>Objectives:</b> To analyze the feasibility and safety of leadless pacemakers in elderly patients. <b>Methods:</b> This retrospective cohort study analyzed 140 patients who underwent leadless pacemaker implantation at People's Hospital of Peking University and People's Hospital of Henan Province between January 2020 and December 2023. The patients were categorized into a non-elderly group (age<75 years) and an elderly group (age≥75 years). The study compared and analyzed demographic information, clinical data, pacing parameters during the surgery and surgery-related complications between the two groups. Pacing parameters (threshold, sensing, and impedance) were monitored in both groups at 24 hours, 3 months, and 6 months post-procedure, and pacing-related complications were recorded. <b>Results:</b> A total of 140 patients were enrolled, with a mean age of (73.6±13.2) years, including 83 males (59.3%). There were 64 patients in the non-elderly group and 76 patients in the elderly group. Compared to the non-elderly group, the elderly group had a lower body mass index, a higher proportion of comorbidities such as atrial fibrillation/atrial flutter, hypertension, coronary heart disease, and stroke, and a lower proportion of postoperative valvular diseases (all <i>P</i><0.05). The elderly group had a higher proportion of patients undergoing leadless pacemaker implantation for the first time (48.7% (37/76) vs. 21.9% (14/64), <i>P</i>=0.001) and a lower rate of leadless pacemaker re-implantation after infection and lead removal (43.4% (33/76) vs. 65.6% (42/64), <i>P</i>=0.006) than the non-elderly group. There were no significant differences in pacing parameters at the time of leadless pacemaker implantation between the two groups (all <i>P</i>>0.05). All patients were successfully implanted with a leadless pacemaker, with only 1 case (0.7%) in the elderly group experiencing pericardial tamponade, which was resolved through puncture and drainage. Additionally, no notable disparities in pacing threshold, sensing, and impedance were observed during the 24-hour, 3-month, and 6-month follow-up periods between the two groups (all <i>P</i>>0.05), and no pacemaker-related complications were observed. <b>Conclusion:</b> Implantation of a leadless pacemaker device in elderly patients (age≥75 years) is safe and effective.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"558-563"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on the relationship between non-high-density lipoprotein cholesterol and cardiovascular disease risk, and clinical management].","authors":"","doi":"10.3760/cma.j.cn112148-20251125-00824","DOIUrl":"10.3760/cma.j.cn112148-20251125-00824","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"518-527"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Triggers of insufficient calorie intake in hospitalized patients with heart failure and their associations with heart failure rehospitalization and cardiovascular death].","authors":"R Y Xi, C X Jia, X R Liu, Z Y Wang, J W Liu, Y F Wu, C Jiang, X Du","doi":"10.3760/cma.j.cn112148-20250819-00588","DOIUrl":"10.3760/cma.j.cn112148-20250819-00588","url":null,"abstract":"<p><p><b>Objective:</b> To explore the causes of inadequate caloric intake for hospitalized patients with heart failure and its association with heart failure rehospitalization and cardiovascular death. <b>Methods:</b> This was an observational study. Patients hospitalized for heart failure in Beijing Anzhen Hospital, Capital Medical University from January 2022 to April 2023 were enrolled. Dietary intake for 3 consecutive days during hospitalization was collected. Patients were divided according to the ratio of the mean actual calorie intake to the theoretical calorie requirement: the insufficient calorie intake group (ratio<0.7) and the sufficient calorie intake group (ratio≥0.7). Baseline clinical characteristics, calorie and nutrient intake, as well as the incidence of heart failure rehospitalization and cardiovascular death within 6 months after discharge were collected and compared between the two groups. Logistic regression models were used to analyze the association between calorie intake and the risk of heart failure rehospitalization and cardiovascular death. <b>Results:</b> A total of 261 patients with heart failure were enrolled, with an age of 59 (48, 67) years, including 196 males (75.1%). There were 136 patients in the insufficient calorie intake group and 125 in the sufficient calorie intake group. Compared with the sufficient calorie intake group, the insufficient calorie intake group had higher proportions of male patients (116 cases (85.3%) vs. 80 cases (64.0%)), patients with no fixed income (83 cases (61.0%) vs. 24 cases (19.2%)), and higher CONUT scores (3 (2, 4) points vs. 1 (1, 3) points) (all <i>P</i><0.05). Follow-up results showed that the incidence of the composite endpoint of heart failure rehospitalization and cardiovascular death was higher in the insufficient calorie intake group than in the sufficient calorie intake group (26 cases (20.6%) vs. 12 cases (9.8%), <i>P</i>=0.017). Multivariate logistic regression analysis showed that insufficient calorie intake was a risk factor for heart failure rehospitalization and cardiovascular death within 6 months after discharge (<i>OR</i>=2.450, 95%<i>CI</i> 1.164-5.158, <i>P</i>=0.018). <b>Conclusions:</b> Male patients and those with no fixed income are more prone to insufficient calorie intake, which is accompanied by poorer nutritional status and higher CONUT scores. Furthermore, insufficient calorie intake is a risk factor for rehospitalization and cardiovascular death in patients with heart failure.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"564-569"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Nomogram incorporating OCT-based plaque morphology and computational physiology features for predicting major adverse cardiovascular events in patients with acute coronary syndrome].","authors":"D M Wang, L Pan, S W Lu, Z J Liu, J Z Yang, Z M Qiu, S Y Yang, Q H Xia, Y C Zhao, R Z Zhao, B Shi","doi":"10.3760/cma.j.cn112148-20260406-00218","DOIUrl":"10.3760/cma.j.cn112148-20260406-00218","url":null,"abstract":"<p><p><b>Objective:</b> To develop a nomogram based on plaque morphological features and derived computational physiological characteristics from optical coherence tomography (OCT) images, and to assess the prognostic value of the nomogram for postoperative outcomes in patients with acute coronary syndrome (ACS). <b>Methods:</b> This retrospective cohort study included ACS patients hospitalized in the Affiliated Hospital of Zunyi Medical University between January 1, 2021 and December 31, 2023. All patients underwent OCT-guided percutaneous coronary intervention (PCI). Data were collected on baseline characteristics, laboratory indices, ancillary examination results, treatment regimens, angiographic data, OCT morphofunctional data. The primary endpoint event was major adverse cardiovascular events (MACE). LASSO regression was used to screen variables, and multivariable Cox regression was employed to establish a model and develop a nomogram. The predictive model was validated using receiver operating characteristic (ROC) curves, calibration curves, and clinical decision curves. Based on the median risk score calculated from the model in the entire cohort, patients were divided into a high-risk group (risk score≥-6.267) and a low-risk group (risk score<-6.267). Kaplan-Meier method was used to plot the survival curves for the two groups of patients. <b>Results:</b> A total of 1 056 patients were enrolled, with a median age of 59 (52, 70) years, of whom 881 (83.4%) were male. The median follow-up duration was 687 days, and 133 (12.6%) patients experienced MACE. Four variables, including symmetry, lipid-fiber cap ratio, mean lumen area, and vascular-level optical flow ratio, were ultimately selected, and a nomogram model was constructed based on these variables. The ROC curve indicated that the area under the curve of this model for predicting MACE at 6, 12, and 18 months after PCI was 0.710, 0.702, and 0.697, respectively. The calibration curve and clinical decision curve demonstrated good consistency and clinical practicality of the model. The Kaplan-Meier survival curve showed that the MACE-free survival rate of patients in the high-risk group was lower than that of the low-risk group (<i>P</i>_log-rank<0.000 1). <b>Conclusion:</b> The nomogram model, established based on the plaque morphological features and computational physiological indicators in OCT images, possesses certain predictive value for the postoperative prognosis of ACS patients.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"544-551"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Astragaloside Ⅳ ameliorates cardiac fibroblast injury induced by the radiation bystander effect and modulates the miRNA-134-5p/BDNF/TGF-β1 signaling pathway].","authors":"J Gu, D Fang, L W Fu, S Jing, M Hou, Y H Xie","doi":"10.3760/cma.j.cn112148-20260310-00154","DOIUrl":"10.3760/cma.j.cn112148-20260310-00154","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the effects of radiation bystander effect mediated by microRNA (miRNA)-134-5p/brain-derived neurotrophic factor (BDNF)/transforming growth factor-β1 (TGF-β1) pathway on cardiac fibroblasts, as well as the protective effect of astragaloside Ⅳ (AST) against fibrotic injury. &lt;b&gt;Methods:&lt;/b&gt; Rat cardiac fibroblasts were used, and a radiation bystander effect model was established via co-culturing cardiac fibroblasts irradiated with 2 Gy X-ray for 1 min with normal cardiac fibroblasts in a Transwell co-culture plate. The experiment was divided into 9 groups: control group (normal cardiac fibroblasts without additional intervention), AST group (normal cardiac fibroblasts pretreated with 5.1 μmol/L AST solution for 2 h), X-co group (irradiated cardiac fibroblasts co-cultured with normal cardiac fibroblasts), X-IN-co group (irradiated cardiac fibroblasts transfected with miRNA-134-5p inhibitor co-cultured with normal cardiac fibroblasts), X-inNC-co group (irradiated cardiac fibroblasts transfected with miRNA-134-5p inhibitor negative control co-cultured with normal cardiac fibroblasts), X-AST-co group (irradiated cardiac fibroblasts pretreated with 5.1 μmol/L AST for 2 h co-cultured with normal cardiac fibroblasts), MI-co group (cardiac fibroblasts transfected with miRNA-134-5p mimic co-cultured with normal cardiac fibroblasts), miNC-co group (cardiac fibroblasts transfected with miRNA-134-5p mimic negative control co-cultured with normal cardiac fibroblasts), and AST-MI-co group (cardiac fibroblasts transfected with miRNA-134-5p mimic co-cultured with cardiac fibroblasts pretreated with 5.1 μmol/L AST for 2 h). Flow cytometry was used to detect the reactive oxygen species (ROS) level in cardiac fibroblasts of each group; Cell Counting Kit-8 assay was used to measure cell proliferation capacity at different time points (0, 6, 12, 24, and 48 h); the thiobarbituric acid method was used to determine malondialdehyde (MDA) concentration; the water-soluble tetrazolium salt method was applied to detect superoxide dismutase (SOD) activity; quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to detect the expression level of miRNA-134-5p; and Western blot was performed to measure the protein expression levels of BDNF, α-smooth muscle actin (α-SMA), TGF-β1, mothers against decapentaplegic homolog 2 (Smad2), and type Ⅰ collagen. &lt;b&gt;Results:&lt;/b&gt; Cell Counting Kit-8 assay showed that the cell viability in all groups was low at 6 h and peaked at 24 h. Compared with the control group, the bystander cells in the X-co group had higher expression levels of miRNA-134-5p, higher levels of ROS and MDA, lower levels of BDNF, and lower SOD activity (all &lt;i&gt;P&lt;/i&gt;&lt;0.05); meanwhile, the protein levels of α-SMA, TGF-β1, Smad2 and type Ⅰ collagen in the bystander cells of the X-co group were higher than those in the control group (all &lt;i&gt;P&lt;/i&gt;&lt;0.05). In comparison with the X-co group, the bystander cells i","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"570-580"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress on the association of cardiac ion channel gene variants with hypertrophic cardiomyopathy and related arrhythmias].","authors":"X Y Ma, J Zhao, B Wang, L W Liu","doi":"10.3760/cma.j.cn112148-20260309-00148","DOIUrl":"10.3760/cma.j.cn112148-20260309-00148","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"600-605"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of intravascular imaging in leave-nothing-behind strategies for coronary intervention].","authors":"T Lin, C Fang, J N Dai, B Yu","doi":"10.3760/cma.j.cn112148-20260116-00037","DOIUrl":"10.3760/cma.j.cn112148-20260116-00037","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"498-502"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[From CKM to MCK: clinical implications of renaming cardiovascular-kidney-metabolic syndrome as metabolic-cardiovascular-kidney syndrome].","authors":"Y M Li, N Yang","doi":"10.3760/cma.j.cn112148-20260222-00106","DOIUrl":"10.3760/cma.j.cn112148-20260222-00106","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"54 5","pages":"503-508"},"PeriodicalIF":0.0,"publicationDate":"2026-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147983710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}