中华心血管病杂志最新文献

{"title":"[Chinese expert consensus on exercise rehabilitation of stable angina pectoris].","authors":"","doi":"10.3760/cma.j.cn112148-20230814-00076","DOIUrl":"10.3760/cma.j.cn112148-20230814-00076","url":null,"abstract":"稳定型心绞痛是常见的冠心病临床类型，在规范的药物及血运重建基础上，运动康复被证实能够减轻或控制稳定型心绞痛患者的症状，提高运动耐量和生活质量，并改善患者的预后，已较广泛地应用于临床。为帮助广大医务工作者在临床工作中规范、合理进行稳定型心绞痛患者的运动康复，中华医学会心血管病学分会、中国康复医学会心肺预防与康复专业委员会、中华心血管病杂志编辑委员会组织专家，根据国内外最新临床研究成果，结合我国国情及临床实践，撰写该专家共识，对稳定型心绞痛患者运动康复的临床研究证据、危险分层评估、运动处方的制订与实施、注意事项等进行全面阐述。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1033-1042"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Hypertrophic cardiomyopathy complicating with ventricular tachycardia induced by MYBPC3 and RYR2 double gene mutations: a case report].","authors":"Z Y Fang, H Wang, Y B Wang, T Sun, F Cao, Y Y Bai","doi":"10.3760/cma.j.cn112148-20230531-00318","DOIUrl":"10.3760/cma.j.cn112148-20230531-00318","url":null,"abstract":"肥厚型心肌病（HCM）是一种常见的遗传性心肌病，临床表现差异较大，多数无临床症状，部分以心原性猝死为首发表现。该文报道1例家族性HCM合并室性心动过速的老年患者，基因测序发现该患者携带HCM4型的明确致病突变MYBPC3基因c.1504C>T杂合错义变异，以及可能与致心律失常右心室发育不良相关的RYR2基因c.6298C>T杂合错义变异，探讨了其临床特征及鉴别诊断，强调了HCM早期筛查、早期诊断、规范治疗的重要性。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1087-1089"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pathological study on the relationship between nucleic acid oxidative stress and heart failure with preserved ejection fraction in patients aged over 85 years].","authors":"W R Zhu,&nbsp;K Chai,&nbsp;F Fang,&nbsp;S R He,&nbsp;Y Y Li,&nbsp;M H Du,&nbsp;J J Li,&nbsp;J F Yang,&nbsp;J P Cai,&nbsp;H Wang","doi":"10.3760/cma.j.cn112148-20230625-00373","DOIUrl":"10.3760/cma.j.cn112148-20230625-00373","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the level of nucleic acid oxidation in myocardial tissue of patients aged over 85 with heart failure with preserved ejection fraction (HFpEF) and the correlation with myocardial amyloid deposition. <b>Methods:</b> This was a retrospective case-control study. Data of patients≥85 years old who underwent systematic pathological autopsy in Beijing Hospital from 2003 to 2017 were retrospectively collected. Twenty-six patients were included in the HFpEF group and 13 age-and sex-matched patients who had not been diagnosed with heart failure and died of non-cardiovascular diseases served as the control group. The left ventricular myocardium slices of both groups were semi-quantitatively analyzed using immunohistochemical staining of 8-oxidized guanine riboside (8-oxo-G) and 8-oxidized guanine deoxyriboside (8-oxo-dG) to evaluate the oxidation of RNA and DNA in cardiomyocytes. Using the median of the mean absorbance value of 8-oxo-G immunohistochemical staining as the cut-off value, patients were divided into high-absorbance group and low-absorbance group. Congo red staining was used to compare myocardial amyloid deposition between the two groups. <b>Results:</b> The mean age of patients in HFpEF group was (91.8±3.7) years, 24 (92.3%) were males. The mean age of patients in control group was (91.7±3.7) years old, 11 (84.6%) were males. The median mean optical absorbance value of 8-oxo-G immunohistochemical staining of myocardium was significantly higher in HFpEF patients than in control group (0.313 8 (0.302 2, 0.340 6) vs. 0.289 2 (0.276 7, 0.299 4), <i>Z</i>=-3.245, <i>P=</i>0.001). The median mean absorbance value of 8-oxo-dG immunohistochemical staining of myocardial tissue was similar between the two groups (0.300 0 (0.290 0, 0.322 5) vs. 0.300 0 (0.290 0, 0.320 0), <i>Z</i>=-0.454, <i>P=</i>0.661). Proportion of patients with moderate and severe cardiac amyloid deposition was significantly higher in the high-absorbance group than in the low-absorbance group ((85.0%, 17/20) vs. (31.6%, 6/19), <i>P</i>=0.001). <b>Conclusion:</b> The RNA oxidation degree of myocardium in HFpEF patients is higher than that in elderly people without heart failure. Degree of myocardial amyloid deposits is higher in patients with high levels of RNA oxidation.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1063-1068"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of conventional echocardiographic features in apical hypertrophic cardiomyopathy patients complicated with left ventricular apical aneurysm].","authors":"Y Zhao,&nbsp;H Wang,&nbsp;K Yang,&nbsp;J R Lin,&nbsp;X Quan,&nbsp;R Qu,&nbsp;S H Zhao","doi":"10.3760/cma.j.cn112148-20230815-00079","DOIUrl":"10.3760/cma.j.cn112148-20230815-00079","url":null,"abstract":"<p><p><b>Objective:</b> To explore the basic characteristics of conventional echocardiography of apical hypertrophic cardiomyopathy (ApHCM) patients complicating with left ventricular apical aneurysm (LVAA). <b>Methods:</b> This is a retrospective study. Patients who underwent echocardiography and cardiac magnetic resonance (CMR) and were diagnosed with ApHCM complicated with LVAA by CMR at Fuwai Hospital, Chinese Academy of Medical Sciences from August 2012 to July 2017 were enrolled. According to whether LVAA was detected by echocardiography, the enrolled patients were divided into two groups: LVAA detected by echocardiography group and LVAA not detected by echocardiography group. Clinical data of the two groups were compared to analyze the causes of missed diagnosis by echocardiography. <b>Results:</b> A total of 21 patients were included, of whom 67.0% (14/21) were males, aged (56.1±16.5) years. Patients with chest discomfort accounted for 81.0% (17/21), palpitation 38.1% (8/21), syncope 14.3% (3/21). ECG showed that 21 (100%) patients had ST-T changes and 18 (85.7%) had deep T-wave invertion. Echocardiography revealed ApHCM in 17 cases (81.0%) and LVAA in 7 cases (33.3%). The mean left ventricular apical aneurysm diameter was 33.0 (18.0, 37.0) mm, and left ventricular ejection fraction was (66.5±6.6) %, and left ventricular apex thickness was (21.0±6.3) mm. Left ventricular outflow tract obstruction was presented in 4 cases and middle left ventricular obstruction in 10 cases. The mean left ventricular apical aneurysm diameter of LVAA detected by echocardiography was greater than that of LVAA not detected by echocardiography (25.0 (18.0, 28.0) mm vs. 16.0 (12.3, 21.0) mm, <i>P</i>=0.006). <b>Conclusions:</b> Conventional echocardiography examination has certain limitations in the diagnosis of ApHCM. Smaller LVAA complicated with ApHCM is likely to be unrecognized by echocardiography. Clinicians should improve their understanding of this disease.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1075-1079"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Challenges and future directions in heart failure with preserved ejection fraction].","authors":"H Wang,&nbsp;J F Yang,&nbsp;Y L Han","doi":"10.3760/cma.j.cn112148-20230725-00023","DOIUrl":"10.3760/cma.j.cn112148-20230725-00023","url":null,"abstract":"射血分数保留的心力衰竭具有发病率高、患者预后及生活质量差、医疗花费高等特点，将成为我国未来重要的公共卫生问题，是心血管领域急需解决的重要难题。该疾病的治疗目前面临着病因复杂、病理生理机制有待阐明、缺乏有效治疗等挑战，临床医师对其重视不够。未来需要加强对射血分数保留的心力衰竭发病机制的研究，寻找药物治疗新靶点，加强预防和早期诊断，注重病因筛查，减少误诊及漏诊，加强综合管理。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1028-1032"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical value of arterial stiffness assessment on risk prediction of vascular stiffness in the octogenarian elderly].","authors":"Y J Wang,&nbsp;Z H Gu,&nbsp;X P Wu,&nbsp;Z Y Fang,&nbsp;T H Wang,&nbsp;S Gao,&nbsp;X Yang,&nbsp;X Y Shen,&nbsp;T Y Zhou,&nbsp;Q Zhang,&nbsp;J X Li,&nbsp;F Cao","doi":"10.3760/cma.j.cn112148-20230530-00316","DOIUrl":"10.3760/cma.j.cn112148-20230530-00316","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to analyze clinical factors related to arterial stiffening and establish a risk prediction nomogram of arterial stiffening in the octogenarian(≥80 years). <b>Methods:</b> This study was a retrospective cross-sectional study, which enrolled the octogenarian elderly who underwent physical examination and secondary prevention intervention in the outpatient department of Chinese People's Liberation Army General Hospital from April 2022 to August 2022. Clinical data including demographics, biochemical indicators and medical history were collected. Brachial-ankle pulse wave velocity (baPWV) was detected during the clinical visit. Participants were divided into the control group (baPWV≤1 800 cm/s) and vascular sclerosis group (baPWV>1 800 cm/s). The risk factors of arterial stiffness were analyzed by univariate and logistic regression analysis, and the nomogram model was constructed by R programming language. The predictive effect of the nomogram model was evaluated by the receiver operating characteristic curve (ROC). <b>Results:</b> The median age of the 525 participants was 87.0 (82.0, 92.0) years, 504 (96.0%) were male, 82 in the control group, 443 in the vascular sclerosis group. The baPWV, age, systolic blood pressure, mean arterial pressure and diastolic blood pressure were significantly lower in the control group than those in the vascular sclerosis group (all <i>P</i><0.05). Logistic regression analysis showed that high-density lipoprotein cholesterol, alanine aminotransferase and amylase were protective factors, and alkaline phosphatase and creatinine were risk factors of arterial stiffening (all <i>P</i><0.05). The combined nomogram model scores including age, mean arterial pressure and the above five laboratory indicators indicated that mean arterial pressure and serum creatinine levels were strongly correlated with vascular sclerosis. The ROC curve suggested that the nomogram model had good prediction ability. <b>Conclusions:</b> Age, mean arterial pressure, high-density lipoprotein cholesterol, alanine aminotransferase, alkaline phosphatase, amylase and creatinine are independently determinants for increased vascular stiffness. The combined prediction model in this study can provide reference for individualized clinical risk prediction of vascular sclerosis in the octogenarian elderly.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 10","pages":"1069-1074"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Catheter ablation technologies for persistent atrial fibrillation: controversies and evaluation].","authors":"S T Li,&nbsp;Q F Li,&nbsp;Y W Lai,&nbsp;C H Sang,&nbsp;C S Ma","doi":"10.3760/cma.j.cn112148-20230605-00329","DOIUrl":"10.3760/cma.j.cn112148-20230605-00329","url":null,"abstract":"肺静脉隔离是房颤消融的基石，然而对于持续性房颤疗效欠佳，尽管目前专家共识均认为持续性房颤消融有必要在肺静脉隔离的基础上进一步进行心房基质改良，但目前的随机对照试验并没有证实肺静脉以外的消融策略可以带来临床获益。随着导管消融技术的进步以及心律失常介入器械的研发，持续性房颤导管消融策略在争议与创新中不断发展进步，本文将针对目前持续性房颤消融技术的进展与争议进行述评。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 9","pages":"909-914"},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10277331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of interventional treatment of aortopulmonary septal defect with Amplatzer duct occlude Ⅱ].","authors":"S Huang,&nbsp;J W Xiao,&nbsp;Q G Wang","doi":"10.3760/cma.j.cn112148-20230202-00056","DOIUrl":"10.3760/cma.j.cn112148-20230202-00056","url":null,"abstract":"主肺动脉间隔缺损（APSD）是一种少见的先天性心脏畸形，一旦诊断应尽早手术治疗。既往多采用外科开胸手术或第一代动脉导管未闭封堵器、膜部或肌部室间隔缺损封堵器介入封堵治疗。该文报道1例体重仅有8.6 kg的APSD患儿，采用第二代Amplatzer动脉导管未闭封堵器进行封堵治疗后，效果良好。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 9","pages":"995-997"},"PeriodicalIF":0.0,"publicationDate":"2023-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transcatheter aortic valve replacement via femoral artery access assisted by Shockwave lithotripsy balloon: a case report].","authors":"Y F Dai,&nbsp;S Y Li,&nbsp;G Y Du,&nbsp;X D Wang,&nbsp;Y Y Huang,&nbsp;J Liu","doi":"10.3760/cma.j.cn112148-20230101-00001","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20230101-00001","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 8","pages":"866-869"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10003488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interventional treatment of outflow tract obstruction and iatrogenic ventricular septal defect after transcatheter aortic valve replacement: a case report].","authors":"Y J Li,&nbsp;X Pan,&nbsp;L Ma,&nbsp;C Wang,&nbsp;B He","doi":"10.3760/cma.j.cn112148-20230628-00377","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20230628-00377","url":null,"abstract":"主动脉生物瓣置换术后瓣膜衰退包括人工瓣叶撕裂、钙化、纤维化及血管翳形成等，可造成瓣膜功能障碍，进而导致生物瓣狭窄或者关闭不全。目前，经导管主动脉瓣置换术（TAVR）已成为老年重度主动脉瓣狭窄的主流治疗方式；该文报道1例TAVR术后瓣下梗阻患者，考虑为严重血管翳形成伴医源性室间隔缺损，采用经导管主动脉瓣中瓣植入术和经皮室间隔缺损封堵术成功完成治疗。.","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"51 8","pages":"862-865"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10012183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}