中华心血管病杂志最新文献

{"title":"[Aortic diseases: progress, clinical challenges, and future prospects].","authors":"Y L Han, Q Y Zhang, X Z Wang","doi":"10.3760/cma.j.cn112148-20241216-00786","DOIUrl":"10.3760/cma.j.cn112148-20241216-00786","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"105-109"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress on perivascular adipose tissue in aortic dissection and aortic aneurysm].","authors":"Z X Zhou, Q Wang, Musaiya Yaermaimaiti Xia, X Ma","doi":"10.3760/cma.j.cn112148-20241014-00605","DOIUrl":"10.3760/cma.j.cn112148-20241014-00605","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"187-191"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk factors for adverse prognosis in acute aortic syndrome: a single-center retrospective cohort study].","authors":"Z C Gao, Y Wang, G S Li, C Yin, D H Qian, J Jin","doi":"10.3760/cma.j.cn112148-20240903-00507","DOIUrl":"10.3760/cma.j.cn112148-20240903-00507","url":null,"abstract":"<p><p><b>Objective:</b> To explore the prognosis of patients with acute aortic syndrome (AAS) in the real world and to examine the risk factors associated with poor outcomes in AAS. <b>Methods:</b> This is a single-center retrospective study. Patients diagnosed with AAS at Xinqiao Hospital from January 2021 to July 2023 were included. The primary endpoints were all-cause mortality and aorta-related mortality, while the secondary endpoints included stroke, myocardial infarction, secondary interventions, and readmission for any cause. Survival analysis was performed using Kaplan-Meier curves, and risk factors for primary endpoint events were analyzed using multivariate Cox regression. <b>Results:</b> A total of 254 AAS patients, aged (58.9±13.2) years were included in this study. There were 178 cases of aortic dissection, 69 cases of aortic intramural hematoma, and 7 cases of aortic penetrating ulcer. The median follow-up time was 545 days. Seventy-three all-cause deaths occurred among patients with AAS, including 61 aorta-related deaths; 3 strokes, 1 myocardial infarction, 9 secondary surgeries, and 35 readmissions for any cause were observed. Kaplan-Meier curve analysis demonstrated significant differences in all-cause mortality rates based on the Stanford classification, AAS disease classification, eGFR, and albumin levels (all <i>P</i><0.05), and similar results were also observed in aorta-related death (all <i>P<</i>0.05). Multivariate Cox regression suggested that albumin<35 g/L (<i>HR</i>=2.372, 95%<i>CI</i> 1.337-4.210, <i>P=</i>0.003), eGFR<90 ml·min^-1·1.73 m^-2 (<i>HR</i>=2.457, 95%<i>CI</i> 1.261-4.786, <i>P=</i>0.008), and Stanford type A AAS (<i>HR</i>=3.420, 95%<i>CI</i> 1.998-5.856, <i>P<</i>0.001) were independent risk factors for all-cause mortality in AAS patients; albumin<35 g/L(<i>HR</i>=2.432, 95%<i>CI</i> 1.295-4.570, <i>P</i>=0.006), eGFR<90 ml·min^-1·1.73 m^-2(<i>HR</i>=2.523,95%<i>CI</i> 1.243-5.122,<i>P</i>=0.010), and Stanford type A AAS (<i>HR</i>=3.455,95%<i>CI</i> 1.819-6.564,<i>P<</i>0.001) were independent risk factors for aorta-related mortality in AAS patients. <b>Conclusions:</b> In the real world, the prognosis of patients with AAS remains pessimistic. Patients with type A AAS, renal dysfunction, hypoproteinemia may have a higher risk of poor prognosis.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"136-142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of coronary and peripheral microvascular endothelial dysfunction in patients with heart failure with non-reduced ejection fraction].","authors":"Y Y Wang, X T Han, Z L Xie, Y Song, S Yuan, S Yao, Y M Xu, X T Cui, J M Zhou","doi":"10.3760/cma.j.cn112148-20241211-00777","DOIUrl":"10.3760/cma.j.cn112148-20241211-00777","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the prevalence, potential risk factors, and correlation between coronary and peripheral microvascular dysfunction in heart failure with non-reduced ejection fraction (nHFrEF) patients. <b>Methods:</b> This was a prospective registry study. nHFrEF patients admitted to Zhongshan Hospital affiliated with Fudan University from December 2021 to December 2023 were enrolled. According to coronary flow reserve (CFR) or reactive congestion index (RHI), enrolled patients were divided into coronary microvascular endothelial dysfunction (CMD) group (CFR<2.5) and no CMD group (CFR≥2.5) or peripheral microvascular endothelial dysfunction (MED) group (RHI<1.67) and no MED group (RHI≥1.67). Patients' general information, laboratory and auxiliary examination data were collected. Univariate and multivariate logistic regression were used to analyze the influencing factors of CMD and MED in nHFrEF patients, and Spearman correlation analysis was used to evaluate the correlation between MED and CMD. <b>Results:</b> A total of 142 nHFrEF patients were enrolled, aged 69.0 (59.0, 74.0) years, with a male proportion of 66.9% (95/142). The grouping results were as follows: (1) According to CFR, there were 73 cases in the CMD group and 69 cases in the no CMD group; (2) According to RHI, there were 57 cases in the MED group and 85 cases in the no MED group. The prevalence of CMD and MED in this study was 51.4% (73/142) and 40.1% (57/142), respectively. Univariate logistic regression analysis showed that increased heart rate, chronic kidney disease, atrial fibrillation, elevated N-terminal pro-B type natriuretic peptide levels, and increased urinary albumin/creatinine ratio were risk factors for CMD, while increased RHI was a protective factor for CMD; Atrial fibrillation is a risk factor for MED, while increased CFR is a protective factor for MED. Incorporating clinically significant variables from univariate analysis into multivariate analysis, the results showed that increased heart rate and elevated RHI remained risk and protective factors for CMD, respectively; increased CFR remains a protective factor for MED. Spearman correlation analysis showed that CFR was negatively correlated with lg urinary albumin/creatinine ratio, lg cardiac troponin T, lg N-terminal pro-B type natriuretic peptide, and heart rate; RHI is positively correlated with CFR. <b>Conclusions:</b> The prevalence of CMD and MED in nHFrEF patients is high, and the two have a certain positive correlation. Increased heart rate and RHI are risk and protective factors for CMD, respectively, while increased CFR is a protective factor for MED. MED may be a potential therapeutic target for nHFrEF patients.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"151-159"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Impact of changes in cardiovascular and cerebrovascular diseases death spectrum on the gender gap in life expectancy among Tianjin residents from 2004 to 2020].","authors":"S Y Wang, T T Jiang, X L Yin, J H Xu, D Z Wang","doi":"10.3760/cma.j.cn112148-20241224-00807","DOIUrl":"10.3760/cma.j.cn112148-20241224-00807","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the impact of changes in cardiovascular and cerebrovascular diseases mortality on the gender gap in life expectancy among Tianjin residents from 2004 to 2020. <b>Methods:</b> This is a cross-sectional study. The data sources included all-cause death surveillance data collected by the Tianjin Centre for Disease Control and Prevention, covering the entire population of Tianjin from 2004 to 2020, and the number of urban and rural residents by age, sex, and urban and rural areas from the Population Management Office of the Tianjin Public Security Bureau during the same period. The abbreviated life table and Arriaga's decomposition method were applied to analyze the cause-of-death surveillance data of Tianjin residents from 2004 to 2020, and to calculate the impact of changes in mortality rates of cardiovascular and cerebrovascular diseases on gender differences in life expectancy by age, subcategory, and urban and rural areas. <b>Results:</b> In 2004, there were 56 189 deaths among Tianjin residents, including 31 233 males and 24 956 females. In 2020, there were 79 782 deaths among Tianjin residents, including 44 829 males and 34 953 females. The gender difference in life expectancy attributable to cardiovascular and cerebrovascular diseases among Tianjin residents increased from 1.52 years in 2004 to 2.02 years in 2020, with females having a longer life expectancy than males. The cumulative impact rate was higher among residents aged 40-74 years, increasing from 26.41% to 33.48%, while the cumulative impact rate among residents aged≥75 declined from 12.66% to 8.54%. The impact rates of intracerebral hemorrhage and cerebral infarction decreased significantly during the observation period, with intracerebral hemorrhage impact rate decreasing from 13.21% to 6.12% and cerebral infarction impact rate decreasing from 11.32% to 5.02%. The impact rate of acute myocardial infarction decreased but remained at a high level, from 9.70% to 6.99%. The impact rate of sequelae of cerebrovascular disease and other coronary heart diseases increased significantly, with the impact rate of sequelae of cerebrovascular disease increasing from 0.54% to 14.42% and the impact rate of other coronary heart diseases rising from 1.35% to 6.34%. The impact of sequelae of cerebrovascular disease deaths on the gender difference in life expectancy was greater in urban areas compared to rural areas, with an increase of 2 101.41% in urban areas and 1 898.51% in rural areas. <b>Conclusions:</b> The gender difference in life expectancy attributable to cardiovascular and cerebrovascular diseases among Tianjin residents is widening. Attention should be paid to the prevention of cerebrovascular disease sequelae and other coronary heart diseases among males aged of 40-74 years in urban areas.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"167-174"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A case of biventricular involvement of arrhythmogenic right ventricular cardiomyopathy associated with PKP2 gene variation].","authors":"M J Huang, R J Han, J Peng, X Q Zeng","doi":"10.3760/cma.j.cn112148-20240730-00424","DOIUrl":"10.3760/cma.j.cn112148-20240730-00424","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"183-186"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Development and validation of the MLR-based nomogram for predicting short-term adverse events in patients with acute uncomplicated type B aortic intramural hematoma].","authors":"Y S Wang, X Wu, Y Wang, T N Zhou, D Y Sun, X Liu, X Z Wang","doi":"10.3760/cma.j.cn112148-20241009-00588","DOIUrl":"10.3760/cma.j.cn112148-20241009-00588","url":null,"abstract":"<p><p><b>Objective:</b> To develop a nomogram based on the monocyte-to-lymphocyte ratio (MLR) for predicting the risk of aortic-related adverse events within 30 days in patients with acute uncomplicated type B aortic intramural hematoma. <b>Methods:</b> This single-center retrospective cohort study screened consecutive patients with acute uncomplicated type B aortic intramural hematoma treated at the Emergency and Cardiovascular Medicine Departments of the General Hospital of the Northern Theater Command from April 2018 to April 2024. Patients were divided into two groups based on the optimal MLR cut-off value for predicting aortic-related adverse events: low MLR and high MLR group. MLR was defined as the ratio of monocytes to lymphocytes. Aortic-related adverse events were defined as a composite of aortic-related death or aortic intramural hematoma progression (including aortic dissection and penetrating aortic ulcers) within 30 days. The receiver operating characteristic (ROC) curve identified the optimal MLR cut-off value. Multivariate logistic regression was used to identify independent predictors of aortic-related adverse events within 30 days, based on which nomogram models were constructed: the clinical characteristics model and the clinical characteristics-MLR model. The DeLong test was used to evaluate the diagnostic performance of different risk models. The additional predictive value of MLR was assessed using the net reclassification index (NRI) and integrated discrimination improvement (IDI). <b>Results:</b> A total of 332 patients were included, of whom 217 were male (65.4%), with an average age of (64.3±9.4) years. A total of 107 aortic-related adverse events occurred during the 30-day follow-up period. The optimal cut-off value for MLR was 0.529. There were 189 cases in the low MLR group (MLR<0.529) and 143 cases in the high MLR group (MLR≥0.529). The rate of aortic-related adverse events was higher in the high MLR group compared to the low MLR group (44.1% (63/143) vs. 23.3% (44/189), <i>P</i><0.001), mainly due to a higher rate of progression to aortic dissection (9.8% (14/143) vs. 1.1% (2/189), <i>P</i><0.001) and penetrating aortic ulcers (31.5% (45/143) vs. 20.6% (39/189), <i>P</i>=0.025). Multivariate analysis identified diabetes (<i>OR</i>=0.25, 95%<i>CI</i> 0.08-0.78, <i>P</i>=0.017), anemia (<i>OR</i>=3.45, 95%<i>CI</i> 1.28-9.27, <i>P</i>=0.014), maximum descending aorta diameter (<i>OR</i>=1.08, 95%<i>CI</i> 1.02-1.15, <i>P</i>=0.007), ulcer-like projections (<i>OR</i>=4.04, 95%<i>CI</i> 2.26-7.24, <i>P</i><0.001), and MLR (<i>OR</i>=6.61, 95%<i>CI</i> 2.50-17.46, <i>P</i><0.001) as independent predictors of aortic-related adverse events during the 30-day follow-up period. The clinical characteristics model includes diabetes, anemia, ulcer-like projections and maximum diameter of the descending aorta, and the clinical characteristics-MLR model includes the above clinical characteristics and MLR. The results of the DeLong","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"128-135"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Predictive value of whole blood cell derived inflammatory markers in combination with NT-proBNP on the prognosis of patients with chronic heart failure].","authors":"Z B Lin, Z H Teng, Y R Xu, Y S Deng, G L Liang, H Y Deng, Q C Zeng","doi":"10.3760/cma.j.cn112148-20241211-00774","DOIUrl":"10.3760/cma.j.cn112148-20241211-00774","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To evaluate the predictive value of whole blood cell derived inflammatory marker (including systemic immunoinflammatory index (SII), systemic inflammatory response index (SIRI), neutrophil count/lymphocyte count (NLR), platelet count/lymphocyte count (PLR), and monocyte count/lymphocyte count (MLR)) and in combination with N-terminal pro-B-type natriuretic peptide (NT-proBNP) on the prognosis of patients with chronic heart failure. &lt;b&gt;Methods:&lt;/b&gt; This study was a retrospective cohort study. Patients with chronic heart failure hospitalized in the Department of Cardiovascular Medicine, Nanfang Hospital, Southern Medical University from January 2019 to August 2022 were enrolled. Patients were followed up and were divided into survival group and death group according to the follow-up results. Clinical characteristics of the two groups were compared. Receiver operating characteristic (ROC) curve was used to determine the optimal cut-off value of each whole blood cell derived inflammatory marker for predicting all-cause death in patients with chronic heart failure. Kaplan-Meier survival curve was drawn, and log-rank test was used to compare the difference in survival of chronic heart failure patients with different levels of whole blood cell derived inflammatory markers. Univariate and multivariate Cox proportional hazards models were used to analyze the effects of whole blood cell derived inflammatory markers and NT-proBNP on the all-cause death of patients with chronic heart failure. ROC curve was used to analyze the predictive value of whole blood cell derived inflammatory markers combined with NT-proBNP on the prognosis of patients with chronic heart failure. &lt;b&gt;Results:&lt;/b&gt; A total of 324 patients with heart failure aged (64.76±13.78) years were enrolled, with 212 males (65.43%). 297 patients (91.67%) completed follow-up, 27 patients (8.33%) were lost to follow-up. The follow-up time was 24.0 (18.0, 41.8) months. There were 258 patients in the survival group and 66 patients in the death group. The optimal cut-off values of SII, SIRI, NLR, PLR and MLR determined by ROC curve were 739.83, 1.65, 3.14, 151.95 and 0.37, respectively. Kaplan-Meier survival curve analysis showed that patients with chronic heart failure with high levels of SII (≥739.83), SIRI (≥1.65), NLR (≥3.14), PLR (≥151.95) and MLR (≥0.37) had higher incidence of all-cause death than patients with low levels of inflammatory markers (all &lt;i&gt;P&lt;/i&gt;&lt;0.001). Multivariate Cox proportional hazard regression analysis showed that age (&lt;i&gt;HR&lt;/i&gt;=1.04, 95%&lt;i&gt;CI&lt;/i&gt; 1.01-1.06, &lt;i&gt;P&lt;/i&gt;=0.002), NT-proBNP (&lt;i&gt;HR&lt;/i&gt;=2.93, 95%&lt;i&gt;CI&lt;/i&gt; 1.64-5.23, &lt;i&gt;P&lt;/i&gt;&lt;0.001), SII≥739.83 (&lt;i&gt;HR&lt;/i&gt;=3.27, 95%&lt;i&gt;CI&lt;/i&gt; 1.18-9.02, &lt;i&gt;P&lt;/i&gt;=0.022) and PLR≥151.95 (&lt;i&gt;HR&lt;/i&gt;=2.67, 95%&lt;i&gt;CI&lt;/i&gt; 1.02-6.96, &lt;i&gt;P&lt;/i&gt;=0.045) were independent predictors of all-cause death in patients with chronic heart failure. ROC curve analysis showed that the predictive value of SII and PLR combined with NT-proBNP","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"143-150"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Role of the Hippo-YAP signaling pathway in cardiomyopathy].","authors":"W Wu, X L Deng, X J Du","doi":"10.3760/cma.j.cn112148-20241025-00645","DOIUrl":"10.3760/cma.j.cn112148-20241025-00645","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 2","pages":"196-201"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Efficacy and safety of intracardiac echocardiography-guided \"one-stop\" procedures combining radiofrequency catheter ablation and left atrial appendage closure in elderly patients with atrial fibrillation].","authors":"X N Shang, M Y Sun, Z L Wang, Z Q Jin, M Liang, J Ding, Y L Han","doi":"10.3760/cma.j.cn112148-20240706-00372","DOIUrl":"10.3760/cma.j.cn112148-20240706-00372","url":null,"abstract":"<p><p><b>Objective:</b> To assess the efficacy and safety of \"one-stop\" procedures combining radiofrequency catheter ablation and left atrial appendage closure by guidance of intracardiac echocardiography(ICE) in elderly patients with atrial fibrillation. <b>Methods:</b> A retrospective cohort study was conducted on patients who underwent ICE-guided \"one-stop\" procedures at the Department of Cardiology, General Hospital of Northern Theater Command between December 2020 and January 2023. Patients were divided into elderly group (age≥60 years old) and non-elderly group (age 18-59 years old). The clinical characteristics, acute success rate, peri-operative complications and follow-up data between two groups were compared. Multivariate logistic regression analysis was used to analyze whether age was the influencing factor for perioperative complications and atrial fibrillation recurrence. <b>Results:</b> A total of 213 atrial fibrillation patients were enrolled, including 158 (74.18%) in the elderly group (age: (68.3±5.0) years; 56.96% male) and 55 (25.82%) in the non-elderly group (age: (53.7±5.2) years; 81.82% male). The elderly group had lower proportions of males, persistent atrial fibrillation, and left atrial spontaneous echocardiographic contrast compared to the non-elderly group (<i>P</i><0.05). CHA₂DS₂-VASc and HAS-BLED scores were higher in elderly group (<i>P<</i>0.05). The acute success rate,\"one-stop\" procedure time, fluoroscopy time and the rate of peri-operative complications (6 (3.80%) in elderly group vs. 2 (3.64%) in non-elderly group) were similar between two groups (all <i>P></i>0.05). The average time of clinical and telephone interviews in elderly group and non-elderly group was (16.9±6.1) months and (17.9±5.9) months, respectively. There was no significant difference in the rate of atrial fibrillation recurrence or clinical events between two groups (47 (30.72%) vs. 14 (26.42%), <i>P</i>=0.554; 10 (6.54%) vs. 2(3.77%), <i>P</i>=0.689, respectively). Iatrogenic atrial septal defects in 3-month transesophageal echocardiography follow up were detected in 44 patients (36.97%) in elderly group and 9 patients (19.57%) in non-elderly group (<i>P=</i>0.032). Multivariate logistic regression analysis results showed that age was not the influencing factor for peri-operative complications and atrial fibrillation recurrence (<i>P=</i>0.905 and <i>P=</i>0.676, respectively). <b>Conclusion:</b> Intracardiac echocardiography-guided \"one-stop\" procedures in the treatment of atrial fibrillation in elderly patients are safe and effective.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 1","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}