中华心血管病杂志Pub Date : 2025-05-26DOI: 10.3760/cma.j.cn112148-20241124-00730
{"title":"[Expert recommendations on clinical application of cardiac myosin inhibitor in patients with obstructive hypertrophic cardiomyopathy].","authors":"","doi":"10.3760/cma.j.cn112148-20241124-00730","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20241124-00730","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20240926-00573
P J Wei, J K Chang, J R Ma, G Z Zhao, J Dong, C Wang, F W Zhang, S G Li, F J Duan, W B Ouyang, S Z Wang, F Fang, X B Pan
{"title":"[Clinical efficacy of transcatheter edge-to-edge repair in patients with non-central degenerative mitral regurgitation].","authors":"P J Wei, J K Chang, J R Ma, G Z Zhao, J Dong, C Wang, F W Zhang, S G Li, F J Duan, W B Ouyang, S Z Wang, F Fang, X B Pan","doi":"10.3760/cma.j.cn112148-20240926-00573","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20240926-00573","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the clinical efficacy of mitral valve transcatheter edge-to-edge repair (TEER) in patients with non-central degenerative mitral regurgitation (DMR). <b>Methods:</b> This retrospective study included patients with non-central DMR who underwent TEER at Fuwai Hospital between January 2021 and February 2024. Patients were categorized into two groups: the commissure-involved group and the non-commissure group, based on whether the mitral valve commissures were involved. Clinical data, surgical outcomes, and echocardiographic findings at 3 months postoperatively were collected and compared, and patients were followed up. The primary endpoint was the procedural success rate at discharge. <b>Results:</b> A total of 59 patients were included, aged (68.6±9.3) years, including 23 females (39%). In the overall study population, 78% (46/59) of patients had severe mitral regurgitation. Forty-two cases were in the non-commissure group, and 17 cases were in the commissure-involved group. Patients in the non-commissure group mainly had lesions in the A1/P1 region, while patients in the commissure-involved group mainly had lesions in the A3/P3 region. There was no significant difference in the procedural success rate at discharge (93% vs. 88%, <i>P</i>=0.95) and the incidence of postoperative complications (5% vs. 6%, <i>P</i>=1.00) between the two groups. Two patients in the commissure-involved group experienced single leaflet device attachment, with one of them requiring conversion to surgical mitral valve surgery; In the non-commissure group, two patients experienced single-valve clamping, and one of them was converted to surgical mitral valve surgery. The follow-up time of the entire cohort was (15.5±10.3) months. In the non-commissure group, 2 patients died and 2 were readmitted. While in the commissure-involved group, no patients died and only 1 patient was readmitted. <b>Conclusion:</b> TEER is an effective treatment for patients with non-central DMR involving the commissures, without increasing the incidence of postoperative complications.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"373-381"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20250113-00038
X R Chen, S H Zhao
{"title":"[Progress in the application of cardiac magnetic resonance for assessing coronary microvascular dysfunction in HFpEF].","authors":"X R Chen, S H Zhao","doi":"10.3760/cma.j.cn112148-20250113-00038","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20250113-00038","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"437-442"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20240828-00485
J Y Jiang, B Li, X P Hu, Q Peng
{"title":"[Anomalous origin of coronary artery misdiagnosed as fulminant myocarditis: a case report].","authors":"J Y Jiang, B Li, X P Hu, Q Peng","doi":"10.3760/cma.j.cn112148-20240828-00485","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20240828-00485","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"402-404"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20241230-00821
J B Hou, Q D Zhao, X T Huang, B Yu
{"title":"[Annual advances in coronary heart disease imaging research 2024].","authors":"J B Hou, Q D Zhao, X T Huang, B Yu","doi":"10.3760/cma.j.cn112148-20241230-00821","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20241230-00821","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"424-428"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20250227-00146
Y T Wang, S H Wang, D Niu, Y J Wang, H Liu, Z X Li, Z J Liu, R Yan, J H Song, J C Guo
{"title":"[Measurement of radial artery diameter by optical coherence tomography via distal radial access].","authors":"Y T Wang, S H Wang, D Niu, Y J Wang, H Liu, Z X Li, Z J Liu, R Yan, J H Song, J C Guo","doi":"10.3760/cma.j.cn112148-20250227-00146","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20250227-00146","url":null,"abstract":"<p><p><b>Objective:</b> To measure the radial artery (RA) diameter and explore its related factors by using optical coherence tomography (OCT). <b>Methods:</b> This was a cross-sectional study conducted in Cardiac Care Unit of Beijing Luhe Hospital, Capital Medical University. Patients who underwent first-ever right forearm access and OCT guided coronary intervention via right distal RA, and measurement of the whole portion of RA diameter with OCT in our center between January 2021 to December 2021 were enrolled. Following the coronary intervention, OCT was used to assess the entire RA. The RA diameter was measured from the RA ostium to 2 cm above the radial styloid process, with a 1 mm interval. Multiple linear regression analysis was performed to determine the factors related the RA diameter. <b>Results:</b> The study enrolled 124 patients with an age of (61.6±12.6) years, of whom 98 (79%) were male. The total length of the RA was (19.5±1.8) cm, for males (20.2±1.3) cm and females (17.2±1.2) cm. The average RA diameter was (3.13±0.50) mm, and the RA diameter at 2 to 5 cm above the radial styloid process was (2.98±0.53) mm. The average RA diameter was significantly larger for male patients than for female patients ((3.21±0.50) mm vs. (2.84±0.37) mm, <i>P</i><0.001). Multiple linear regression analysis indicated that gender was significantly associated with RA diameter (<i>P</i>=0.019). <b>Conclusions:</b> The average RA diameter measured by OCT is (3.13±0.50) mm, (2.98±0.53) mm at 2 to 5 cm above the radial styloid process. Gender is identified as a factor related to the RA diameter.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"388-393"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20250128-00074
H Xu, M F Xia, J Li
{"title":"[Research progress on the role of mechanically sensitive ion channel Piezo1 in vascular remodeling].","authors":"H Xu, M F Xia, J Li","doi":"10.3760/cma.j.cn112148-20250128-00074","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20250128-00074","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"452-456"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20250305-00169
T H Wang, D Han, F Cao
{"title":"[Research and application progress of 3D bioprinting technology in repairation of cardiovascular injury].","authors":"T H Wang, D Han, F Cao","doi":"10.3760/cma.j.cn112148-20250305-00169","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20250305-00169","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"443-447"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20250111-00032
J Hu, W Tan, W Zhang
{"title":"[Research progress on the role of CaN/NFAT signaling pathway activated by Ca<sup>2+</sup> overload in hypertensive cardiac hypertrophy].","authors":"J Hu, W Tan, W Zhang","doi":"10.3760/cma.j.cn112148-20250111-00032","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20250111-00032","url":null,"abstract":"","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"448-451"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华心血管病杂志Pub Date : 2025-04-24DOI: 10.3760/cma.j.cn112148-20241213-00783
X P Lin, W X Hu, Q F Zhu, H H Li, J Liang, H X Yan, L H Wang, P Hu, J B Jiang, K D Ren, J Q Fan, Y X He, X B Liu, J A Wang
{"title":"[Transcatheter edge-to-edge repair strategies for mitral commissural prolapse: a single-center experience].","authors":"X P Lin, W X Hu, Q F Zhu, H H Li, J Liang, H X Yan, L H Wang, P Hu, J B Jiang, K D Ren, J Q Fan, Y X He, X B Liu, J A Wang","doi":"10.3760/cma.j.cn112148-20241213-00783","DOIUrl":"https://doi.org/10.3760/cma.j.cn112148-20241213-00783","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the feasibility of transcatheter edge-to-edge repair (TEER) using a short-clip strategy for patients with moderate-to-severe or greater degenerative mitral regurgitation caused by commissural prolapse. <b>Methods:</b> This retrospective study included patients with severe mitral regurgitation secondary to commissural prolapse who underwent TEER at the Second Affiliated Hospital of Zhejiang University School of Medicine between September 2022 and July 2024. Preoperative clinical and imaging data, intraoperative details, procedural outcomes, and 1-month postoperative follow-up results were collected. <b>Results:</b> A total of 19 patients were enrolled, aged (74.1±6.1) years, including 12 males. Among them, 10 patients had external commissural prolapse, and 9 patients had internal commissural prolapse. Preoperatively, all patients exhibited severe mitral regurgitation (4+), with an effective regurgitant orifice area of (0.55±0.17) cm², left atrial volume of (104.77±36.57) ml, left ventricular end-diastolic volume of (102.29±32.47) ml, left ventricular end-diastolic dimension of (5.34±0.59) mm, and prolapse width of (1.18±0.34) cm. All procedures utilized short clips (NTR or NTW clips) to target the prolapsed commissural region and were completed successfully without intraoperative complications. At 1-month follow-up, no mortality, stroke, single-leaflet device attachment, myocardial infarction, or unplanned mitral reintervention occurred. Mitral regurgitation severity improved to ≤2+ in all patients, with left atrial volume of (74.49±33.83) ml, left ventricular end-diastolic volume of (85.90±18.05) ml, and left ventricular end-diastolic dimension of (4.93±0.37) mm (all <i>P</i><0.05). <b>Conclusion:</b> The short-clip strategy, focusing on precise clip placement at the commissural interface, is feasible and effective for TEER in patients with severe mitral regurgitation due to commissural prolapse.</p>","PeriodicalId":38755,"journal":{"name":"中华心血管病杂志","volume":"53 4","pages":"356-362"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}