Vojenske Zdravotnicke Listy最新文献_第7页

DRUG-INDUCED ACUTE PANCREATITIS - LITERATURE OVERVIEW AND OUR EXPERIENCE 药物性急性胰腺炎的文献综述及经验

Vojenske Zdravotnicke Listy Pub Date : 2022-04-06 DOI: 10.31482/mmsl.2022.016

J. Csomor, P. Hříbek, P. Urbánek

引用次数: 0

VITAMIN E VERSUS PROPOLIS AS AN ADD-ON THERAPY TO SITAGLIPTIN/METFORMIN ON OXIDANT/ANTIOXIDANT STATUS AND LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS 维生素e与蜂胶作为西格列汀/二甲双胍的附加治疗对2型糖尿病患者氧化/抗氧化状态和血脂的影响

Vojenske Zdravotnicke Listy Pub Date : 2022-04-04 DOI: 10.31482/mmsl.2022.015

Sarraa Dhiaa, I. Thanoon, Nabeel N. Fadhil

{"title":"VITAMIN E VERSUS PROPOLIS AS AN ADD-ON THERAPY TO SITAGLIPTIN/METFORMIN ON OXIDANT/ANTIOXIDANT STATUS AND LIPID PROFILE IN TYPE 2 DIABETIC PATIENTS","authors":"Sarraa Dhiaa, I. Thanoon, Nabeel N. Fadhil","doi":"10.31482/mmsl.2022.015","DOIUrl":"https://doi.org/10.31482/mmsl.2022.015","url":null,"abstract":"the of modulation of lipid in type 2 diabetic patients using E for comparison in sequential mode i.e. vitamin E used for 8 washout period and then propolis therapy started in the same group of patients (n = 45). Thereby a sample of serum has been collected in the first visit (baseline and vitamin E started, followed by collecting serum after 8 weeks (second visit); followed by commencing of propolis after a washout week from the second visit, at the third visit another serum sample collected from all patients. Serum was analyzed for oxidant/antioxidant status represented by malondialdehyde (MDA) and total antioxidant status (TAS). Additionally, lipid profile has been measured from the same samples. The results indicate that both propolis and vitamin E positively modulated the measured parameters with superiority of propolis over vitamin E in improving these measured biomolecules. To conclude, propolis is an overall safe natural product and is inducing such positive effects in the diabetic patient, we do advise these patients to start propolis therapy as an adjuvant medication to control these deleterious biomolecules.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43357985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

BIOCHEMICAL STUDY OF SERUM β-HYDROXYBUTYRATE DEHYDROGENASE IN β-THALASSEMIA β地中海贫血患者血清β-羟基丁酸脱氢酶的生化研究

Vojenske Zdravotnicke Listy Pub Date : 2022-03-31 DOI: 10.31482/mmsl.2022.013

Hiba Sami, M. Fakhri

{"title":"BIOCHEMICAL STUDY OF SERUM β-HYDROXYBUTYRATE DEHYDROGENASE IN β-THALASSEMIA","authors":"Hiba Sami, M. Fakhri","doi":"10.31482/mmsl.2022.013","DOIUrl":"https://doi.org/10.31482/mmsl.2022.013","url":null,"abstract":"Introduction: Thalassemia is a healthcare challenging disease all over the world. It imparts a great burden on patients’ families and healthcare institutions. Scientists focus on new aspects to overcome these challenges and increase patient tolerance of disease complications. This study aims to quantify β-Hydroxybutyrate Dehydrogenase BHBDH activity in thalassemia patients compared to the control group and their correlation with the patient's demographic characteristics. Methods: To do so, serum was collected from patients and the control group and analyzed biochemically for targeted laboratory tests. We determined β-Hydroxybutyrate Dehydrogenase from normal human serum using biochemical molecular techniques. Results: The results showed that BHBDH activity is significantly higher in the patients compared to the control group regardless of age, sex, or marital status. The results confirmed that enzyme activity and the purification folds were (0.0214 U/ml) and (51.7) respectively for the partially purified enzyme. Furthermore, the proportional molecular weight of the incompletely isolated β-Hydroxybutyrate Dehydrogenase was (125.8±0.5 kDa) using gel filtration chromatography. The comparative molecular weight of the subunit of partially isolated β-Hydroxybutyrate Dehydrogenase was (32.1±0.5 kDa) using SDS–PAGE. Conclusion: we demonstrate that BHBDH enzymatic activity is higher than control and this could be a prognostic or diagnostic tool in thalassemia patients.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41868904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CLOSTRIDIAL COLLAGENASE IMMOBILIZED ON CHITOSAN NANOFIBERS FOR BURN HEALING 壳聚糖纳米纤维固定化梭菌胶原酶用于烧伤愈合

Vojenske Zdravotnicke Listy Pub Date : 2022-03-17 DOI: 10.31482/mmsl.2022.012

M. Slováková, R. Köhlerova, P. Dvořáková, Veronika Vánová, Martina Špačková, Marcela Munzarová

{"title":"CLOSTRIDIAL COLLAGENASE IMMOBILIZED ON CHITOSAN NANOFIBERS FOR BURN HEALING","authors":"M. Slováková, R. Köhlerova, P. Dvořáková, Veronika Vánová, Martina Špačková, Marcela Munzarová","doi":"10.31482/mmsl.2022.012","DOIUrl":"https://doi.org/10.31482/mmsl.2022.012","url":null,"abstract":"This article describes the characterization and application of collagenase-based chitosan nanofiber membranes with rat burns. Electrospun chitosan nanofibers were functionalized with clostridial collagenase using carbodiimide chemistry. The immobilized collagenase was characterized by enzyme activity, kinetic constants, and dry storage stability measurements using a Pz-peptide substrate. The apparent kinetic constants K M and V max of immobilized collagenase showed a high affinity for the peptide substrate compared to the free enzyme. Drying of chitosan membranes with immobilized collagenase ensured 98 % stability of enzyme activity after rehydration. The effect of collagenase immobilized on chitosan nanofibers on the burn of the rat model was compared with a control treatment with chitosan nanofibers. The healing of the wound with both materials was terminated after 30 days at the same time, although the collagenase wound healed more rapidly during healing. The scar area size after the application of collagenase-containing chitosan nanofiber membranes was 31.6 % smaller than when only chitosan nanofibers were used.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43152548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VARIATION OF CALCIUM DISTRIBUTION IN DIFFERENT ORGANS OF LIVER FLUKE FASCIOLA HEPATICA 肝吸虫肝吸虫不同器官钙分布的变化

Vojenske Zdravotnicke Listy Pub Date : 2022-03-17 DOI: 10.31482/mmsl.2022.011

H. Sadoon, B. Al-Sabawi, Sundus N. Al-Kallak

引用次数: 0

THE CORRELATION BETWEEN L-CARNITINE UPTAKE AND SOME HEMATOLOGICAL PARAMETERS IN OXIDATIVE STRESSED RATS 氧化应激大鼠左旋肉碱摄取与血液学指标的关系

Vojenske Zdravotnicke Listy Pub Date : 2022-03-16 DOI: 10.31482/mmsl.2022.007

O. B. Aghaa, Hind T. Hamad

{"title":"THE CORRELATION BETWEEN L-CARNITINE UPTAKE AND SOME HEMATOLOGICAL PARAMETERS IN OXIDATIVE STRESSED RATS","authors":"O. B. Aghaa, Hind T. Hamad","doi":"10.31482/mmsl.2022.007","DOIUrl":"https://doi.org/10.31482/mmsl.2022.007","url":null,"abstract":"The objective of this research was to determine the effect of L-carnitine antioxidant ability on some hematological parameters such as the extent of red blood corpuscles (RBCs), \"Packed cells volume (PCV)\", Hemoglobin (Hb), and Mean cellular volume (MCV) in normal and oxidative stress exposed rats respectively. Using an animal model, \"Hydrogen peroxide ((H2O2 0.5 %)\" was mixed with drinking tap water to induce oxidative stress through the experiment period (30 days). Three groups were used in this study (each containing 7 rats) one of them was the negative control group and the other two were the positive control group (oxidative stress group treated with H2O2) and the treatment group treated with H2O2 + L-carnitine. The oxidative stress group showed a significant decrease (P<0.05) in RBCs count, and no significant differences (P<0.05) were observed in Hb, PCV, and MCV compared with the control group on the other hand the treatment group revealed a significant increase (P<0.05) in RBCs count in cooperation with the oxidative stress group. It can be concluded that L-carnitine has a positive key role toward H2O2 induced oxidative stress. This role positively affects the red bone marrow and erythropoiesis through balancing the negative effect of oxidative stress and can be monitored through RBCs count only.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44657553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EPICARDIAL FAT IN PATIENTS UNDERGO LAPAROSCOPICAL-SLEEVE GASTRECTOMY 腹腔镜胃切除患者的心外膜脂肪

Vojenske Zdravotnicke Listy Pub Date : 2022-03-15 DOI: 10.31482/mmsl.2022.008

Faris M. Lolan, Abdullah S. Mahmood, Yasser F. Al-Gburi

{"title":"EPICARDIAL FAT IN PATIENTS UNDERGO LAPAROSCOPICAL-SLEEVE GASTRECTOMY","authors":"Faris M. Lolan, Abdullah S. Mahmood, Yasser F. Al-Gburi","doi":"10.31482/mmsl.2022.008","DOIUrl":"https://doi.org/10.31482/mmsl.2022.008","url":null,"abstract":"Introduction: Obesity is increasingly reported to be a contributing factor to vascular diseases resulting in increased patient morbidity and mortality rates leading to increase healthcare expenses. More precisely, the lipid deposition in cardiac tissues is interesting, due to their direct contribution to the disease initiation, prognosis, and all subsequent patients’ fate. We do focus on the determination of the link between changes in body mass index (BMI) and epicardial fat deposition concerning gastric operation. Objective: The objective of this work was to study the relationship between weight reduction and \"epicardial thickness\" after laparoscopic-sleeve gastrectomy. Methods: Critically-ill patients were recruited from private clinics and out-patients hospital clinics. Forty-two patients undergoing laparoscopic-sleeve gastrectomy due to morbid obesity were included in this research. Patients followed for four months after the operation. Results: The results of this work find there is significant weight reduction in these patients in parallel with a reduction of epicardial fat thickness. Conclusion: Patients who experience laparoscopic-sleeve gastrectomy showed a reduction in weight in a parallel reduction in epicardial fat thickness.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41627495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COMPARATIVE STUDY OF IRON STATUS IN APPARENTLY HEALTHY PREGNANT WOMEN WITH NON PREGNANT WOMEN 表面健康孕妇与非孕妇铁含量的比较研究

Vojenske Zdravotnicke Listy Pub Date : 2022-02-16 DOI: 10.31482/mmsl.2022.006

Ahmed H. AL-Hamdani

{"title":"COMPARATIVE STUDY OF IRON STATUS IN APPARENTLY HEALTHY PREGNANT WOMEN WITH NON PREGNANT WOMEN","authors":"Ahmed H. AL-Hamdani","doi":"10.31482/mmsl.2022.006","DOIUrl":"https://doi.org/10.31482/mmsl.2022.006","url":null,"abstract":"Iron status in this clinical trial was represented as \"Serum Iron, Total iron˗ binding capacity (TIBC), Unsaturated iron˗ binding capacity (UIBC), Transferrin saturation, Packed cell volume (PCV), Hemoglobin (Hb)\", were evaluated in the blood of 98 healthy participant women, including 35 healthy non-pregnant women aged between (18-45) years as a control group and 63 healthy pregnant women aged between (15-44) years which divided into two groups depending on gestational age, the first group in the first trimester aged between (15-38) years; the second group in the third trimester aged between (21-44) years; in order to investigate the impacts of pregnancy and gestational period on iron status. The dedication of the contemporary research was to conclude the physiological changes in iron conditions in pregnant women in relation with non-pregnant women. Regarding this results that are recorded in the current research, a great significant drop in the level of the serum iron, transferrin saturation, PCV, Hb in \"the first and third trimester\" of pregnant women when comparison done with the control cases, while a statistical significance elevation of TIBC and UIBC level in the first and third trimester of pregnancy compared with control groups. Finally, the results of the mean value of iron status showed a meaningful difference between the first and third trimesters of pregnancy.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46224550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A ROLE FOR INFLAMMATORY IL-6 IN THE DEVELOPMENT OF CORONARY ARTERY DISEASE: A CASE CONTROL STUDY AT AL-QADISIYAH GOVERNORATE, IRAQ 炎症性IL-6在冠状动脉疾病发展中的作用：伊拉克AL-QADISIYAH省的病例对照研究

Vojenske Zdravotnicke Listy Pub Date : 2022-02-11 DOI: 10.31482/mmsl.2022.005

Ajil A. Alzamily, Mohammed N. Al-Delfi, Aqeel R Al-Barqaw

{"title":"A ROLE FOR INFLAMMATORY IL-6 IN THE DEVELOPMENT OF CORONARY ARTERY DISEASE: A CASE CONTROL STUDY AT AL-QADISIYAH GOVERNORATE, IRAQ","authors":"Ajil A. Alzamily, Mohammed N. Al-Delfi, Aqeel R Al-Barqaw","doi":"10.31482/mmsl.2022.005","DOIUrl":"https://doi.org/10.31482/mmsl.2022.005","url":null,"abstract":"Background: Disruption of the IL-6 axis can result in the beginning or progression of a variety of disease states, including cardiovascular diseases. Because of IL-6's pathogenic function, pharmacologic manipulation of the IL-6 axis is a sensible therapeutic strategy;nevertheless, various expected, yet frequently overlooked, effects on tissues and organs other than blood vessels may also occur. The study's goal is as follows: The purpose of this study is to see how inflammatory Interleukin-6 affects the development of coronary artery disease. Materials and Methods: Serum IL-6 level was estimated using Elabscience® kits. A case-control study included 30 CAD patients, 30 positive controls (PC) [(have family history for CAD)], and 30 negative controls (NG) [they have no family history for CAD]. Ranged from 30 to 81 years old. Patients with acute or chronic illnesses such as liver disease, renal disease, thyroid function disorders, COVID-19, and autoimmune disease were excluded from the study. During the period from December 2020 to May 2021. Our study was included other factors such as ages, genders, smoking, family history, antihypertensive drugs or drugs for other diseases, body mass index (BMI) which were assessed. Results: The results of this study show increased levels of IL-6 in patients with CAD compared with the PC and NC These results showed a highly significant difference (p < 0.0001) in the concentrations compared with PC and NC. Conclusions: IL-6 could be one of the prognostic signs of CAD. © 2022, University of Defence, Faculty of Military Health Sciences. All rights reserved.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48124196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

PREMENSTRUAL SYMPTOMS SCREENING AND SELF-MEDICATION AMONG WOMEN IN RIYADH, SAUDI ARABIA 沙特阿拉伯利雅得妇女经前症状筛查和自我用药

Vojenske Zdravotnicke Listy Pub Date : 2022-02-10 DOI: 10.31482/mmsl.2022.002

E. Alshammari, Khlood Aldossary

{"title":"PREMENSTRUAL SYMPTOMS SCREENING AND SELF-MEDICATION AMONG WOMEN IN RIYADH, SAUDI ARABIA","authors":"E. Alshammari, Khlood Aldossary","doi":"10.31482/mmsl.2022.002","DOIUrl":"https://doi.org/10.31482/mmsl.2022.002","url":null,"abstract":"Most women experience some premenstrual symptoms regularly. Because of this, PMS/ PMDD has emerged as a 20 century phenomenon, mostly since women now have better control over reproduction. The symptoms associated with these conditions may be minimal, moderate, or severe depending on the ratings of the symptoms recorded daily. Women also continue to report lower levels of productivity in the 5 to 10 days after the start of menses. As part of exploring these conditions, the study sought to examine the screening of premenstrual symptoms and self-medication acts among women in Riyadh, Saudi Arabia. The findings were as follows. There were 56 participants in the study, with their ages ranging between 18 and 54. Most of the participants were also either working or students. Regarding diagnosis, nearly half of the sample (n=27, 48.2 %) were diagnosed as normal, while 4 out of 10 study participants (n=23, 41.1 %) had PMS. Additionally, 10.7 % were diagnosed as having both PMDD and PMS. On self-medication, the findings revealed that 1 out of every 2 study participants (n=28, 50 %) self-medicated to ease PMS/PMDD. Among the 28 persons, only 17 (60.17 %) had PMS/PMDD. These findings suggest that nearly half of persons who did not have PMS/PMDD self-medicated themselves thinking that they had PMS/PMDD. The findings of this study provide government and other policymakers with the data required to inform debate and to increase access to public health. Having established a sensible belief that PMS may substantially affect women in Saudi Arabia, further studies might estimate the magnitude of the problem.","PeriodicalId":38749,"journal":{"name":"Vojenske Zdravotnicke Listy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47703176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0