A. N. Naumenko, Maksym V. Tarasenko, Mykhailo Yu. Bolgov
{"title":"Surgical treatment of unilateral laryngeal paralysis by selective reinnervation in thyroid surgery","authors":"A. N. Naumenko, Maksym V. Tarasenko, Mykhailo Yu. Bolgov","doi":"10.37219/2528-8253-2022-3-51","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-51","url":null,"abstract":"State of the problem: One of the complications in thyroid surgery is a lesion of RLN which can be bilateral with a violation of respiratory function of the larynx and unilateral, in which the first priority is a violation of vocal function of the larynx. The most effective treatment for paralysis of the larynx is the method of laryngeal reinnervation, which can be non-selective, which is usually used in unilateral laryngeal paralysis and promotes reinnervation of both abductors and laryngeal adductors. Selective reinnervation is selectively focuses on the reinnervation of individual target muscles, so it is more often used in bilateral laryngeal paralysis. But despite this, it was used in unilateral laryngeal paralysis during surgery on the thyroid gland during intentional resection of the anterior branch of RLN with partial invasion of its tumour process.\u0000Aim: evaluation of the results of surgical treatment unilateral laryngeal paralysis by the method selective reinnervation in thyroidectomy.\u0000Materials and Methods: clinical case results of patient A. 15 years old with papillary thyroid cancer and metastases to regional lymph nodes of the neck (T4aN1M0) with absence disorders of laryngeal motility before surgery were analyzed. Examination of the larynx and voice examination were performed before surgery, 2-3 days and 6,12 months after surgery. Changes of laryngoscopic images and evaluation of the Indicators: maximum pho-\u0000nation time, fundamental frequency, noise to harmonic ratio, Jitter (loc), Shimmer (loc), Voice Handicap Index-30 (VHI-30), completed version of Jacobcon B.\u0000Results: Considering extralaryngeal bifurcation of the recurrent laryngeal nerve (RLN) and invasion of the tumor into the adductive branch of RLN on the left, its dissection was performed and end-to-end neuroanastomosis was formed, completed is selective laryngeal reinnervation. In the immediate postoperative period, patients complained of voice disorders. Study of voice parameters corresponded to severe voice disorders.\u0000Partial resumption of the mobility of the larynx and voice function was after 6 months. The signs of the laryngoscopic picture and the spectral analysis of the voice corresponded to the indicators before the operation after 12 months\u0000Сonclusions\u00001. Primary selective reinnervation of the larynx can be used to treat unilateral laryngeal paralysis under the following conditions: extralaryngeal branching of the recurrent laryngeal nerve (bifurcation), lesion of only one of its branches, which will provide sufficient coaxiality to perform anastomosis \"end-to-end\" and preservation electrical integrity of another branch.\u00002. This method allows you to restore the motility of the denervated vocal folds and the main indicators of the voice.\u00003. Given only one clinical case of treatment of unilateral laryngeal paralysis by selective reinnervation, this technique needs further study and refinement.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"402 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89027116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low patient compliance to CPAP therapy as a new challenge in the management of patients with obstructive sleep apnea syndrome: social, demographic characteristics and the quality of life","authors":"Julia V. Dieeva","doi":"10.37219/2528-8253-2022-3-44","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-44","url":null,"abstract":"Introduction: Obstructive sleep apnea syndrome (OSAS) is one of the most common sleep disorders. According to various studies, the prevalence of OSAS varies between 2-4% of men and 1-2% of women in the general population, with more than 90% of cases among men and 80% of women being undiagnosed. The \"gold standard\" for the treatment of OSAS is respiratory therapy using CPAP. At the same time, the results of patients' compliance to CPAP are controversial. Thus, the inability to use this method was noted by 45 to 80% of patients, therefore it is important to study this group of patients, who showed low compliance with CPAP.\u0000Aim: to determine the social and demographic characteristics of the group of patients with OSAS and low compliance with CPAP therapy, as well as the impact of the disease on the quality of life of patients.\u0000Materials and methods: The study included 80 patients with second stage OSAS who had previously demonstrated low compliance with CPAP. Overall demographic indicators were assessed, and patients were interviewed to assess their quality of life using The Assessment of Quality of Life (AQoL) instrument. Statist ical criteria included methods of descriptive statistics (mean, mode, median, minimum and maximum value, variance). In case of normal data distribution methods of parametric statistics were used, and in case of uneven distribution – non-parametric criteria.\u0000Results: The gender distribution in the group showed 67.5% of men and 32.5% of women. Average age was 39.35 (±9.49) years and 39.56 (±11.89) years, respectively. The average value of the biomass index in men was 28.3 (±2.9), in women – 28.1 (±3.9). Only three people in the group reached retirement age. The results of the survey of the quality of life showed a significant reduction in the level of \"Relationships with others\", \"Social isolation\", \"Sleep\" and \"Anxiety and depression\" (p <0.05).\u0000Conclusions: The results of the study showed that the demographic characteristics of the group of patients with OSAS with low compliance to CPAP do not differ from the general patterns.\u0000In addition, a questionnaire using The Assessment of Quality of Life (AQoL) instrument showed a significant decrease in the quality of life of patients due to worsening of social isolation and reduced psychological wellbeing.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89160941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Shchelkunov, S. Pukhlik, O.V. Titarenko, Oleksandr A. Shchelkunov
{"title":"Development and improvement of methods of conservative treatment of stylohyoid syndrome","authors":"A. Shchelkunov, S. Pukhlik, O.V. Titarenko, Oleksandr A. Shchelkunov","doi":"10.37219/2528-8253-2022-3-77","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-77","url":null,"abstract":"Stylohyoid syndrome is a disease caused by irritation of the surrounding nerve, vascular and muscle structures by the styloid process, located at the temporal bone. The syndrome is manifested by chronic pain in the deep part of the lateral region of the face, radiating to the root of the tongue, pharynx and ear, dysphagia, and symptoms of cerebral circulatory disorders.\u0000The purpose of the study: to develop and improve accessible, safest and not leaving pronounced cosmetic defects, methods of conservative treatment of patients with stylohyoid syndrome and prevention of the recurrence of the described symptoms in the future.\u0000Materials and methods of research: Our work was aimed at improving and simplifying the methods of conservative and surgical treatment of patients with symptoms of stylohoid syndrome, taking into account the data of CT studies with contrast and functional tests and palpation of the oropharynx, as well as using functional tests , to determine the smallest distance of the apex of the styloid process of the temporal bone to the lateral wall of the oropharynx and determine the most optimal region for the injection of a medicinal substance.\u0000The material for our research and proposals was the examination and treatment of 204 patients over a 10-year period. Of these, there were 143 women (71%), men – 61 (30%), age – from 25 to 70 years old, 25-30 years old – 21 people (8.1%), 30-45 years old – 123 (63%), 45-60 years old – 42 (20.6%), 60-70 years old – 18 (8.1%); duration of the disease – from 1 to 10-15 years. Injections into the region of the apex of the styloid process must necessarily be supplemented with drug therapy. Out of 204 patients, the success of treatment at 0 points (no complaints) was assessed by 96 people (47%), at 1 point – by 64 (31.4%), at 2-3 points – by 31 (15.1%), at 4-5 points (that is, no significant effect of the treatment was achieved) – 13 (6.4%). Everyone who had a treatment result of 4-5 points was offered a surgical method of treatment – resection of the styloid process from the corresponding side.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"51 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85427103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Data of clinical otorhinolaryngologic review of servicemen of armed forces of Ukraine are at implementation of the educational firing","authors":"L. Petruk, R. P. Kramarenko","doi":"10.37219/2528-8253-2022-3-18","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-18","url":null,"abstract":"Lately medical help is provided in many medical institution of Ukraine for those servicemen who suffered of the influence of intensive noise during implementation of duties of military service. Before sending in the zone of battle actions for implementation of the assigned tasks, servicemen of certain military branches pass training for improving of their skills, including, handling a weapon. The actual task is to reveal in time violations that can lea to the development of defeat of the auditory system under action of sounds of high intensity in the conditions of realization of battle actions in future.\u0000Aim: to define changes in otorhinolaryngologic status of servicemen of AFU during the implementation of the educational firing on a polygon.\u0000Materials and methods: the otorhinolaryngologic inspection of 53 servicemen is conducted at age from 18 to 37 and after realization of firing from a rifle armament (gun-machine of Kalashnikov without and with subbarrel grenade launcher) on a polygon.\u0000Results and their discussions: After realization of series of shots in parts of servicemen certain changes were revealed in ENT status. During the otoscopy of some patients (11.3%) was revealed the injection of the vessels by the way of handle of hammer, in 5 (9.4%) cases during the otoscopy was marked certain smoothness of the contours of eardrums and reduction of light reflex. Worth mentioning that 10 (18.8%) patients inspected after training felt high-frequency subjective noise. 2 fighters (3.7%) ment ioned moderate dizziness after implementation of shots. 5 (9.4%) servicemen had complaints about a moderate headache after training. Majority of them noted that such a feeling passed during an hour after firing. However, in 7.5% cases such complaints took the place after this term. And exactly at this group of inspected we also looked after changes at an otoscopy. We guided such fighters at a further instrumental inspection for detection of possible violations in functioning of auditory analyzer as a result of the noise influence. To our opinion, such persons should be examined in relation to the presence of preclinical violations in an auditory analyzer and possible increase of individual sensitiveness to noise influence . There is a risk, which in the zone of battle actions in case of acousticbarotrauma the severe defeat of the auditory system can develop in such fighters.\u0000Thus, due to the conducted examination by otolaryngologist. increases the possibility of revealing the person with high sensitiveness to the noise influence in time that help determine the limitations that can be applied in this case, It is expedient to use possibility to prevent development of heavy hearing loss and invalidisation of servicemen, that has socio-economic consequences.\u0000Conclusions:\u00001. During the implementation of the educational firing some servicemen can suffer from the violations of the state of the auditory system, which looks like the changes of otoscopic picture and the p","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73712393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Shidlovskaya, T. Shidlovskaya, N. Kozak, K. V. Ovsyanik, L. Petruk
{"title":"Indicators of bioelectrical activity of the brain according to EEG data in patients with acute trauma received in real combat conditions, taking into account the effectiveness of medical measures","authors":"T. Shidlovskaya, T. Shidlovskaya, N. Kozak, K. V. Ovsyanik, L. Petruk","doi":"10.37219/2528-8253-2022-3-11","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-11","url":null,"abstract":"Topicality: The research conducted by the authors shows that acute trauma in combat conditions is accompanied by persistent psychophysiological disorders of the central nervous system, but a significant part of these studies is based on clinical observation data. The technique of electroencephalography (EEG) allows you to objectively assess the state of the central nervous system and provides a better understanding of neurophysiological processes in patients with sensorineural deafness (SND) with acute trauma, which will contribute to the development of more effective rehabilitation methods for this contingent of patients.\u0000Aim: to evaluate the indicators of bioelectrical activity of the brain according to electroencephalography (EEG) data in servicemen who received acute trauma in real combat conditions, with different effectiveness of treatment measures.\u0000Materials and methods: 2 groups of servicemen with combat acute trauma were examined: 1 group - patients with positive dynamics of treatment, 2 group - patients with insufficient effectiveness of treatment, and 15 healthy normal-sensing individuals of the control group. The electroencephalographic study was carried out with the help of a computer electroencephalograph of the company \"DH-systems\" (Ukraine).\u0000Results: All patients underwent a comprehensive, instrumental examination. The examined subjects had sensorineural deafness with a descending, often abrupt, type of tonal audiometric curve, with the most pronounced and reliable increase in hearing sensitivity thresholds in the region of 4, 6, and 8 kHz.\u0000According to the analysis of EEG indicators, in the patients examined by us, the most characteristic were a decrease in the bioelectric activity of the brain and disorganization of cortical rhythms with signs of dysfunction of the diencephalon-stem structures. At the same time, the decrease in bioelectric activity most often occurred in the frontal and temporal leads. Thus, in patients of group 1, during the background recording, the content of the delta rhythm was (13,61±0,37) and (9,96±0,29) %, respectively, which significantly exceeds the control indicators (8,5±1,6) and (5,3±1,5) % (Р<0,05). During photostimulation and hyperventilation in the frontal leads, the content of slow-wave activity significantly exceeded the control indicators. During photostimulation, the content of the\u0000delta rhythm in patients of group 1 was (14,23±0,38) and (7,3±1,4) % in the control group.\u0000In the comparative analysis of EEG indicators between the studied groups, an increase in the representation of slow-wave activity in frontal projections and a decrease in the share of alpha rhythm in patients of group 2 is noted. Thus, in frontal leads during background recording in patients of groups 1 and 2, the delta rhythm content was (13,61±0,37) and (16,95±0,25) %, respectively. Moreover, these trends were preserved both during background recording and during functional loads.\u0000Therefore, patients with combat acute traum","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80369318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. I. Yashan, O. Pokryshko, M. Herasymiuk, Artem O. Yashan, Pavlo O. Buchynskyi
{"title":"Evaluation of the effectiveness of natural oromukos throat spray from sunflower flower extracts in the treatment of acute pharyngitis in adults","authors":"O. I. Yashan, O. Pokryshko, M. Herasymiuk, Artem O. Yashan, Pavlo O. Buchynskyi","doi":"10.37219/2528-8253-2022-3-82","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-82","url":null,"abstract":"Acute pharyngitis is a common disease among the adult population. The most common causative agents of acute inflammatory diseases of the pharynx are β-hemolytic streptococci.\u0000Oromucous sprays, which are used in this case for treatment, are a special dosage form that ensures the spraying of particles of the active substance and their adhesion to the mucous membrane of the oral cavity and pharynx.\u0000The purpose of the study: to determine the therapeutic effect and the level of bacteriological colonization of the drug \"Lorosan\" for the treatment of acute pharyngitis.\u0000Materials and methods: 32 patients, aged from 20 to 27 years, with symptoms corresponding to the nosological form of acute pharyngitis were examined. Clinical examination of patients was carried out at the beginning of the disease and one week after treatment with Lorosan. The clinical effectiveness of the drug was determined by analyzing changes in complaints and the condition of the mucous membrane of the oropharynx.\u0000Results: After using the drug \"Lorosan\" for 7 days, all patients noted a decrease in pain in the throat, a significant decrease in the sensation of a foreign object in the throat and the number of secretions, normalization of the general condition and full recovery of the voice. The number of caseous tonsillitis in the tonsillar lacunae decreased, and the unpleasant smell from the mouth disappeared.\u0000The obtained results of the microbiological study of the biomaterial taken after 7 days of treatment with the drug \"Lorosan\" showed a sharp decrease in the number of microorganisms and the level of their spread of the posterior pharynx.\u0000Thus, the new natural oromucous spray from sunflower is an effective drug in the monotherapy of acute pharyngitis in adults, as it allows to significantly reduce the clinical symptoms of the disease and significantly reduce the bacterial colonization of the oropharynx by the causative agents of inflammatory processes.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80452787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Shidlovskaya, Julia B. Burlaka, N. Voroshilova, L. Petruk, Sergiy V. Verevka
{"title":"Features of the hemostatic system at combat-caused acoustic injuries","authors":"T. Shidlovskaya, Julia B. Burlaka, N. Voroshilova, L. Petruk, Sergiy V. Verevka","doi":"10.37219/2528-8253-2022-3-02","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-02","url":null,"abstract":"Introduction: Exposure to high-intensity sounds can cause significant damage to the human auditory system. Joint damage to the auditory system by high-intensity sound and shock waves causes acubarotrauma. Such lesions are systemic in nature, affecting not only the auditory system but also the entire human body. It significantly impairs the quality of life and general condition of the body, causes numerous complications. Therefore, the issues of diagnosis and treatment of hearing impairments caused by acutraumas and acubarotraumas received in combat conditions are highly relevant. Aim: to study the hemostatic indices of patients with combat-caused acoustic trauma and identify the most informative ones. Patients and methods: 22 patients with combat acoustic trauma and 10 healthy volunteers were tested. The object of the study was citrate plasma, which was obtained by standard methods. The content of fibrinogen was determined by thrombin-like enzyme Ancistron-H. Partially activated thromboplastin time and prothrombin time were determined by tests of Siemens, USA. The share of functionally inactive forms of prothrombin was determined by Ecamulin-based diagnostic test. The content of protein C activity was determined by cleavage of synthetic chromogenic substrate (Siemens, USA). The concentrations of soluble fibrin and D-dimer were evaluated by immunodiagnostic test systems \"DIA-soluble fibrin\" and \"DIA-D-dimer\" (Diaprof-Med, Ukraine). Statistical processing of the results was performed by WinPEPI package for biometric statistical processing with Student's t-test for evaluation of the difference between patients and the control group. Results and discussion: It was found that fibrinogen’s level in 25% of patients remained at the level of control. In 27% of patients this index decreased on the level of the trend, and in 50% - increased 1.6 times. The elevat ion of fibrinogen’s level proves for a risk of thrombotic complications, since this acute phaseprotein is well-known index of hypercoagulability. Partially activated thromboplastin time index in 14% of the tested group remained at the level of control values. In 14% of patients it was probably 1.4 times shorter, and in 73% of patients it was 1.6 times longer than control. Prolonged partially activated thrombin time may prove for the increased level of circulating coagulation factor VIII. In 82% of patients the index of prothrombin time was probably 2.4 times prolonged, where as in 18% of patients was almost at the level of control. It may prove for an imbalance between the components of blood clotting system. The indices of Ecamulin-based test were multidirectional. In 18% of patients it was on the level of control, in 55% of patients it was slightly shorter, and in 27% of patients - probably elongated 1.4 times. The level functionally inactive forms of prothrombin in 50% of patients didn’t differ of control values, in 23% it was tended to decrease, and in 27% it was 1.6 more. The latter proves f","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86462609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peculiarities of bone tissue metabolism in patients with acute otitis media with impared carbonhydrate metabolism","authors":"T. Pochuiеva, A. Filatova","doi":"10.37219/2528-8253-2022-3-23","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-23","url":null,"abstract":"Introductions: Relevance of the study is due to the unrecognized effect of carbohydrate metabolism disorders on bone tissue metabolism in patients with acute otitis media (AOM).\u0000Aim: to determine the peculiarities of bone tissue metabolism in patients with AOM caused by disorders of carbohydrate metabolism.\u0000Materials and methods: Our study included 73 patients aged 18 to 79 (29 males and 44 females) who were randomized into 4 groups according to the aim of the research:\u0000Group 1 – 17 patients with AOM,\u0000Group 2 – 15 patients with AOM combined with paranasal sinus pathology,\u0000Group 3 – 20 patients with AOM on the background of type 2 diabetes mellitus,\u0000Group 4 – 21 patients with AOM combined with transitory disorders of glucose metabolism.\u0000On the basis of clinical examination all patients were tested for glycosylated hemoglobin (HbAlc), blood calcium level and parathormone as a marker of bone resorption and osteocalcin as a marker of bone remodeling.\u0000Results of the study and discussion: The statistical evaluation of the indicators identified a reliable difference between groups 1-2 and groups 3-4, while between groups 1 and 2, 3 and 4 reliable difference in metabolic parameters of bone tissue has not been established. The level of glucosylated hemoglobin was significantly elevated even for transitory signs of carbohydrate metabolism disorders (5,17±0,17%, 4,95±0,17%, 9,8±0,46% and 7,78±0,19% in groups 1,2, 3 and 4 respectively).The value of parathormone was within the reference values, but it proved to be significantly (p˂0,001) higher in glucose metabolism disorders (56.8±3.02pg/ml and 52.56±2.7pg/ml in groups 3 and 4, respectively).The amount of osteocalcin and calcium tended to decrease in type 2 diabetes mellitus (group 3) and in transitory disorders (group 4), but without a significant difference (p˃0.05).\u0000Correlation analysis revealed a strong correlation between glucose and glucosylated hemoglobin levels in patients in group 3 and the average strength in patients in group 4 (r=0.832 and r=0.44, respectively). The increase of parathormone level on the basis of carbohydrate metabolism disorders was due to the presence of correlation with the level of glucosylated haemoglobin in groups 3 and 4 (r=0.705 and r=0.81 respectively). Calcium correlations of r=-0.77 and r=-0.56 with parathormone level and r=-0.79 and r=-0.44 with glucosylated haemoglobin level were found in patients of groups 3 and 4 accordingly. In the absence of glucose metabolism disorders in groups 1 and 2, no significant correlations were found, except for physiologically determined correlations of parathormone and calcium levels in group 1 (r=-0.489).\u0000Conclusions: Disorders of carbohydrate metabolism negatively affect metabolism of bone tissue due to activation of bone resorption processes. This is manifested by correlated with the level of glycosylated hemoglobin by an increase in the amount of parathormone with pathogenetic significance of both type 2 diabetes mellitus and trans","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83600557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of extended alar batten graft with Tajima reverse U incision for unilateral cleft rhinoplasty: a case control study","authors":"S. Pendem, Vaishnavi Sripathi","doi":"10.23736/s2724-6302.22.02420-3","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02420-3","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74462762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of hyaluronic acid on mucocillary clearance after septoplasty","authors":"A. Khammas, M. Dawood, Ban I. Ali","doi":"10.23736/s2724-6302.22.02421-5","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02421-5","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78106664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}