Evaluation of the effectiveness of natural oromukos throat spray from sunflower flower extracts in the treatment of acute pharyngitis in adults

Q4 Medicine

Otorhinolaryngology Clinics Pub Date : 2022-07-29 DOI:10.37219/2528-8253-2022-3-82

O. I. Yashan, O. Pokryshko, M. Herasymiuk, Artem O. Yashan, Pavlo O. Buchynskyi

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Abstract

Acute pharyngitis is a common disease among the adult population. The most common causative agents of acute inflammatory diseases of the pharynx are β-hemolytic streptococci. Oromucous sprays, which are used in this case for treatment, are a special dosage form that ensures the spraying of particles of the active substance and their adhesion to the mucous membrane of the oral cavity and pharynx. The purpose of the study: to determine the therapeutic effect and the level of bacteriological colonization of the drug "Lorosan" for the treatment of acute pharyngitis. Materials and methods: 32 patients, aged from 20 to 27 years, with symptoms corresponding to the nosological form of acute pharyngitis were examined. Clinical examination of patients was carried out at the beginning of the disease and one week after treatment with Lorosan. The clinical effectiveness of the drug was determined by analyzing changes in complaints and the condition of the mucous membrane of the oropharynx. Results: After using the drug "Lorosan" for 7 days, all patients noted a decrease in pain in the throat, a significant decrease in the sensation of a foreign object in the throat and the number of secretions, normalization of the general condition and full recovery of the voice. The number of caseous tonsillitis in the tonsillar lacunae decreased, and the unpleasant smell from the mouth disappeared. The obtained results of the microbiological study of the biomaterial taken after 7 days of treatment with the drug "Lorosan" showed a sharp decrease in the number of microorganisms and the level of their spread of the posterior pharynx. Thus, the new natural oromucous spray from sunflower is an effective drug in the monotherapy of acute pharyngitis in adults, as it allows to significantly reduce the clinical symptoms of the disease and significantly reduce the bacterial colonization of the oropharynx by the causative agents of inflammatory processes.

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向日葵花提取物天然喷喉剂治疗成人急性咽炎的疗效评价

急性咽炎是成年人的常见病。咽部急性炎症性疾病最常见的病原体是β-溶血性链球菌。在这种情况下用于治疗的口腔喷雾剂是一种特殊的剂型，可确保活性物质颗粒的喷洒及其粘附在口腔和咽部的粘膜上。研究目的:确定“洛散”治疗急性咽炎的疗效和细菌定植水平。材料与方法:对32例年龄在20 ~ 27岁，症状符合急性咽炎分类学表现的患者进行检查。患者在发病初期和用罗生治疗一周后进行临床检查。通过分析患者的主诉变化及口咽部粘膜状况，判断该药的临床疗效。结果:所有患者用药7 d后，咽喉疼痛减轻，咽喉异物感和分泌物数量明显减少，一般情况恢复正常，声音完全恢复。扁桃体腔隙内干酪样扁桃体炎数量减少，口腔异味消失。用“洛山”药物治疗7天后所取生物材料的微生物学研究结果显示，后咽的微生物数量及其扩散水平急剧下降。因此，向日葵新型天然口咽喷雾剂是成人急性咽炎单药治疗的有效药物，因为它可以显着减少疾病的临床症状，并显着减少炎症过程病原体在口咽部的细菌定植。

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来源期刊

Otorhinolaryngology Clinics Medicine-Otorhinolaryngology

CiteScore

0.10

自引率

0.00%

发文量

期刊介绍： Otorhinolaryngology Clinics: An International Journal is an International periodical devoted at exploring connections between clinical experience and world literature, and understanding of various pathologies and diseases related to the ear, nose and throat. Issues of recent advancements and research related to disease, illness, health and medical science are examined through various evidence-based clinical research studies. This journal proposes to serve as a collection of clinical notes, with an international perspective, along with the recent advances for postgraduates and consultants. The readership for this journal would include a wide variety of healthcare professionals, such as otolaryngologists, head and neck surgeons, ENT nurses as well as scholars and academicians in the field of medicine, trauma, surgery, etc. This journal aims to encourage the analysis of clinical data from various centers all over the world using standardized protocols to develop an international consensual perspective on the management of disorders related to the field of otorhinolaryngology. Recently, we have introduced "Case Reports", "How I Do It" and "Original Research" categories in the process of expanding the scope of the journal. Thisis a peer-reviewed journal of which three issues would be published each year. Each future issue will cover a different topic of special interest in the field of otorhinolaryngology and head and neck surgery. This issue is the first of its kind dedicated to "anesthesia in otorhinolaryngology" and contains a compilation of articles by experienced anesthesiologists dealing with a large volume of ENT and related surgeries. In each issue, the editors give their perspective based on the submitted articles. All non invited articles are peer-reviewed. Peer-revieweing helps in providing unbiased, independent, critical assessment of the results of the research study in question including the scientific process.