Otorhinolaryngology Clinics最新文献

{"title":"Sudden sensorineural hearing loss: does a seasonal variation exist? A single-center retrospective study in Italy and a review of literature","authors":"A. De Giorgi, A. Ciorba, F. Fabbian, C. Bianchini, Virginia Corazzi, F. Stomeo, S. Pelucchi, R. Manfredini","doi":"10.23736/s2724-6302.22.02428-8","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02428-8","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85095080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descriptive epidemiology of parotid neoplasms in central Italy: a multicenter retrospective study","authors":"A. Rocco, P. Ruscito, A. Marzetti, Francesco Tauro, F. Cianfrone, A. Loperfido, Silvia Sessi, D. Rosati, A. Celebrini, G. Bellocchi","doi":"10.23736/s2724-6302.22.02434-3","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02434-3","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83292261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear implant in inner ear malformations: the experience of the ENT clinic of university of Pisa","authors":"F. Lazzerini, F. Forli, L. Bruschini, S. Berrettini","doi":"10.23736/s2724-6302.22.02449-5","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02449-5","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77858978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audiological impairment in multiple sclerosis: the role of neuroinflammation","authors":"L. Maiolino, S. Ferlito, Stefania Saitta, I. La Mantia","doi":"10.23736/s2724-6302.22.02445-8","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02445-8","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85729869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical value in using both paradigm HIMP and SHIMP with video head impulse test in patients with vestibulopathy","authors":"L. Manzari, A. A. Princi, M. Tramontano","doi":"10.23736/s2724-6302.22.02450-1","DOIUrl":"https://doi.org/10.23736/s2724-6302.22.02450-1","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78599896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disorder of sound conduction function in patients with COVID-19","authors":"M.I. Bezega","doi":"10.37219/2528-8253-2022-3-65","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-65","url":null,"abstract":"Topicality: Recently, due to the pandemic of the new virus COVID-19, a significant number of patients have been observed in almost all countries of the world, presenting various clinical manifestations of the disease. The auditory system can also suffer when infected with COVID-19. In the publications of several authors, observation of concomitant cochleovestibular manifestations in COVID-19 is presented. In addition, there are reports of sensorineural hearing loss, tinnitus, vertigo, otitis, and ear pain. However, there is still not enough information on auditory system lesions in patients with COVID-19 in the literature; so far, there are no thorough studies in this direction.\u0000Aim: to investigate the state of auditory function in patients with COVID-19 with sound conduction disorders.\u0000Materials and methods: An analysis of the clinical and instrumental examination results of 47 patients with COVID-19 with auditory function disorders was carried out. The results of the questionnaire, otolaryngological examination, subjective audiometry, and acoustic impedance measurement were analyzed. The investigation was carried out using audiometers АС-40 (\"Interacoustics,\" Denmark), and MA 31 (Germany), impedance audiometers АТ-235, Ad 229e, (\"Interacoustics,\" Denmark), and MAICO (Germany). In addition, an endoscopic examination of the nasal cavity was carried out using the workplace of an otorhinolaryngologist with the Mega Medical NET-1100 endovideo complex.\u0000Results and their discussion: The analysis of the survey of 147 patients revealed that damage to the auditory system mainly occurred after a particular time after suffering from the disease due to COVID-19. Some patients (15.6%) had a progression of pre-existing SNS; in them, the first signs of deterioration of auditory function were usually noted a few days after the onset of the disease. In total, among 147 interviewed patients, 51 people (34.7%) indicated certain disorders of the auditory system. At the same time, the patients noted such symptoms as tinnitus, decreased hearing acuity, impaired speech intelligibility, poor tolerance to loud sounds, blocked ears, and unpleasant sensations in the ears (feeling of pressure, tingling, dull pain).\u0000During the instrumental examination of 47 patients with COVID-19 with complaints from the auditory system, we mainly observed sensorineural disorders of auditory function. In 23.4% of cases, there was a conductive component. In the majority of such patients after COVID-19, they do not immediately notice symptoms in the auditory system. Instead, they have an unexpressed character and appear over time after the disease. Such hearing disorders are often accompanied by secretory otitis, tubootitis, and auditory tube patency disorder.\u0000It should be noted that in patients (19.1%) with a conductive component, there were changes in the anatomical structures of the nose and nasopharynx in the form of curvature of the nasal foramen, hypertrophy of the nasal shells, tubular","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73088713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute otitis externa. Diagnosis and treatment according to modern clinical guidelines","authors":"V. Popovych","doi":"10.37219/2528-8253-2022-3-88","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-88","url":null,"abstract":"Acute external otitis – is an infectious and inflammatory disease of the skin of the external auditory canal, which is more common in adults, less often in children. The most frequent causative agents of acute external otitis are Pseudomonas aeruginosa (20-60%) and Staphylococcus aureus (10-70%), the frequency of fungal flora does not exceed 10% and is not significant from the point of view of empirical prescription of antifungal drugs. Propensity to the disease is caused by a hot and humid climate, swimming, traumatization of the skin of the auditory canal, comorbid diseases. Patients with acute otitis externa are mainly outpatients and do not require inpatient treatment. Empiric therapy of uncomplicated acute external otitis determines the appointment of local ototopic drugs in the form of drops, which include a combination of polymyxin B, neomycin, which provides a bactericidal effect on typical pathogens, and glucocorticoid dexamethasone. Effective local treatment is facilitated by thorough cleaning of the external auditory canal. The criterion for the effectiveness of the treatment is the reduction of pain, itching and congestion within 48-76 hours and recovery within seven days.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82355160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiopathogenetic grounding of the treatment of voice-speech professions with functional dysphonia on the background of subclinical psycho-emotional disorders during the COVID-2019 pandemic","authors":"I. Sinaiko, Vasyl I. Troyan, Veronica M. Kryshtal","doi":"10.37219/2528-8253-2022-3-57","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-57","url":null,"abstract":"The aim of the research: Improvement of the traditional complex treatment of voice-speaking professions during the COVID-2019 pandemic with functional dysphonia on the background of subclinical psycho-emotional disorders by appointment neurotransmitter drugs.\u0000Materials and methods: The study involved 49 people of voice-speech professions with functional disorders of the voice function of the hypotonic type, who were diagnosed with subclinical disorders of the psychoemotional state by questioning on the hospital anxiety and depression scale (HADS). Before and after treatment, voice disorders were diagnosed using perceptual evaluation of the GRBAS voice scale and video stroboscopy of the larynx. The impact of voice disorders on quality of life during the pandemic was assessed using the Voice COVID-19 (VC-19) questionnaire.\u0000All patients received standardized treatment, which consisted of the use of metabolic, stimulant drugs, physiotherapy and instillation of drugs into the larynx. In 26 patients of the main group (MG), in addition to treatment, a neurotransmitterotropic drug (\"Beresh Magnesium plus B6\") was prescribed. The comparison group (CG) consisted of 23 people who received traditional therapy. Descriptive statistics were used for statistical analysis of the effectiveness of treatment, comparison of the difference in quantitative indicators by the method of nonparametric statistics using the Mann-Whitney-U-test.\u0000Results: The use of the neurotransmitter correction agent \"Beresh Magnesium plus B6\" by the patients with MG contributed to the suppression of their susceptibility to anxiety, stress and, as a result of these processes, made it possible to obtain, in comparison with the control group, a significant improvement in such indicators of acoustic parameters as voice strength by 5.78%, integral stroboscopy index - 13.34% and improvement of the quality of life by 34.03%, which indicates the effectiveness of the use of magnesium compounds with vitamin B6 in the complex treatment of patients with hypotonic dysphonia against the background of subclinical psychoemotional disorders.\u0000Conclusions: Addit ional appointment of magnesium citrate and magnesium oxide compounds with vitamin B6, which has a modulating effect on neurotransmitters that affect depression and anxiety, to basic therapy for patients of main group, made it possible to obtain a significant improvement in the main perceptual and functional indicators of the voice and quality of life.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90452124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regeneration of artificial injuries external ear elastic cartilage of rabbits after stem cells local injection","authors":"Yuriy V. Minin, P. Virych, Anton F. Karas, S. P. Chaika, Halyna A. Karas, N. Shuvalova, T. Kucherenko","doi":"10.37219/2528-8253-2022-3-36","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-36","url":null,"abstract":"Introduction: Every year, a large number of patients from developed countries turn to surgical departments with the reconstruction problems of the auricle cartilage. A some of surgical procedures was developed to correct minor defects due to the low regenerative capacity of elastic cartilage. Stem cells can potentially differentiate into chondroblasts and chondrocytes and restore cartilage integrity. Many factors influence on the differentiation and proliferation of stem cells, which complicates the method application. Therefore, the investigation of using stem cells to regeneration elastic cartilage is relevant.\u0000Aim: clarification the regeneration features of the artificial defect of the rabbits’ ear elastic cartilage after the stem cells injection.\u0000Materials and methods: The investigation was conducted on rabbits of chinchilla breed aged 1.5 months, weighing 2.5 kg. Artificial lesions measuring 2 x 7-10 mm were simulated on the cartilaginous plate of the outer ear with a scalpel. 0.5 ml of stem cell suspension (~5 million) obtained from the umbilical cord of rabbits by enzymatic method was injected into the defect site. Histological sections of the cartilage defect were prepared. The samples were stained by Weigert and Azure II methods. The relative density of collagen, elastin fibers, oxyphilic and basophilic tissue elements was programmatically evaluated.\u0000Results and discussion: The amount of fibers in the native elastic cartilage was more on 35% of the relative dermis. The newly formed tissues at the damage cartilage was like to the dermis after 2 months. Similar results were found on ear in 2.5 and 3 months after surgery. Native cartilage on histological sections almost was not oxyphilic. Maybe a significant number of acidic components was masked it. Dense connective tissue contains almost equal amounts of both components. Thus, it is possible to trace changes in the intercellular matrix that will characterize the direction of the regeneration process. The area of elastic cartilage defect was characterized by a significant presence of oxyphilic elements after 2 months of the stem cells addition. The ratio of oxyphilic and basophilic components in the native elastic cartilage was about to zero. For the dermis was 1.4-1.5. Dense scar connective tissue was characterized by a ratio about 1. Based on the results obtained, was assumed that the direction of stem cell proliferation is determined shortly after injection.\u0000Conclusion: The addition of stem cells to the area of the artificially created elastic cartilage defect of the rabbit's ear was not allow to obtain stable regenerative processes of cartilage tissue and the restoration of the intercellular matrix to its original state.\u0000The process of stem cell differentiation contributes the formation of dense connective tissue of the scar, which may be due to the presence of proinflammatory cytokines, growth factors and other biologically active molecules. This was not creating the necessary conditi","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89545794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Our observations regarding olfactory disorders in COVID-19","authors":"Bohdan Bezeha","doi":"10.37219/2528-8253-2022-3-71","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-3-71","url":null,"abstract":"Topicality: Despite a large number of patients and, accordingly, the large number of publications in the medical literature, numerous clinical manifestations of the disease due to COVID-19 have not yet been sufficiently studied. One of the leading symptoms of COVID-19 is impaired olfactory function, primarily anosmia. According to the literature, anosmia is noted in 30 to 60% of patients. It can be an early and sometimes the only characteristic symptom of the disease. Treatment of olfactory disorders is a difficult task. Therefore timely detection of disorders and early targeted therapy is of great medical and social importance. Aim: to determine the features of the clinical manifestations of olfactory dysfunction in patients with COVID-19. Materials and methods: An analysis of the clinical and instrumental examination of 53 pat ients with COVID-19 was carried out. In addition, an endoscopic examination of the nasal cavity was carried out using the workplace of an otorhinolaryngologist with the Mega Medical NET-1100 endovideo complex. Results and their discussion: According to the analysis of survey data of 130 patients with the help of a particular questionnaire developed by us to determine sensory organ function disorders in patients with COVID-19, the majority of subjects (69.2% of cases – 90 patients) noted olfactory function disorders, mainly in the form of anosmia 25.4% (33 patients) or weakening of olfactory sensitivity by 22.3% (29 patients). However, in 21.5% (28 patients) of cases, the sense of smell or its enhancement was distorted. Mainly, smell impairment occurred in the first few days of the disease, and hearing was partially or wholly restored after recovery. However, in 26.2% - 34 patients, certain disorders persisted for 1-3 months after the illness, and in 15.3% - 20 patients, the sense of smell did not fully recover five months after recovery. We examined 53 patients who became ill with COVID-19 and complained of impaired olfactory function, which persisted after recovery from 2 weeks to 1.5 months, mainly in the form of complete anosmia 34% (18 patients), weakening of olfactory function 26, 4% (14 patients) and distortion 39.6% (21 patients). In general, according to our observations, independent recovery (primarily partial) is observed in patients with COVID-19 within 2 to 6 months, and more often, it occurs with changes in sensitivity and distortions of the perception of some smells. According to the endoscopic data, 54% of the examined had no visible signs of mucosal disorders. It was pink, hydrated, and without signs of inflammation, thinning, hypertrophy or oedema. In 13 patients (24.5%), there was an increase in the vascular pattern and moderate oedema. Seven patients (13.2%) showed signs of dryness and thinning of the mucous membrane, sometimes with crusts. Approximately 79.3% (42 patients) of the examined subjects had anatomical features that partially or significantly limited air access to the olfactory zone (upp","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80040373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}