Otorhinolaryngology Clinics最新文献

{"title":"Changes in the organism of patients with chronic inflammatory diseases of the upper respiratory tract at different periods after administration of influenza vaccine.\u0000Message 1. Status of congenital immune parameters after a single anti-influenza vaccination","authors":"O. Melnikov, D. Zabolotnyi, O. Rylska, Мarina D. Timchenko, T. Zayets, S. Timchenko, T. Sidorenko","doi":"10.37219/2528-8253-2022-1-21","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-1-21","url":null,"abstract":"Introduction: Studies of the clinical status, production of antibodies to hemagglutinins of influenza A and B viruses and the content of immune complexes in patients with chronic inflammatory diseases (CID) of the upper respiratory tract (URT) before and within 36 weeks of vaccination after parenteral vaccination Vaxigrip leads to a short-term (~ 6 months) increase in anti-influenza hemagglutinin t itres. According to modern ideas about the mechanisms of antiviral protection, in addition to humoral, mainly due to antibodies, antiviral protection is largely due to the activation of innate immune factors, both systemic and local.\u0000Aim: to evaluate in the dynamics of observations the influence of a single parenteral influenza vaccination on the factors of innate immunity in patients with chronic inflammatory diseases of the upper respiratory tract.\u0000Material and methods: Among the factors of innate immunity a significant role is played by interferons, the activity of natural cytolytic cells (NK) of various histogenesis, phagocytic cells and non-specific proteins such as defensins, elafins. Therefore, quantitative and functional characteristics of NK-cells, phagocytic absorption activity of polymorphonuclear leukocytes (PMN), systemic content of γ-interferon (IFN-γ) were studied in patients at the systemic level. At the local level, the concentrations of defensin-β and α-interferon were studied in mucosa secretes (MS) according to modern ideas about the state of the mechanisms of innate antiviral immunity.\u0000From the autumn-winter period of 2019 to November 2020, 32 donors (control group) and 32 patients with CID of both sexes were examined, 11 of whom were diagnosed with chronic rhinosinusitis, 9 with chronic tonsillitis, and 12 with chronic pharyngitis. No vaccinations were given 1 year before the study.\u0000Samples of venous serum and oropharyngeal secretes of all clinically healthy patients, as well as persons with CID were obtained at the initial examination. After parenteral vaccination with Vaxigrip (SANOFI PASTEUR, S.A., France), blood and MS were tested twice more in vaccinated patients: 12 and 36 weeks after vaccination. The obtained samples of experimental material were stored at a temperature of -20 C◦ until the simultaneous determination of innate immune factors (interferons), in particular with the help of reagents from Cytokine, Hema Medica (RF), defensin-β (Hucalt-bio, the Netherlands). Measurements were performed on a microplate enzyme-linked immunosorbent assay \"STAT FAX 2100 (USA).\u0000Statistical processing was performed using the non-parametric criterion \"U\" - Mann-Whitney or Fisher's exact method. Differences were considered statistically significant at p <0.05. The results were given in the form of arithmetic mean (M), median (Me) and percentiles (P25-P75).\u0000Results: In determining the role of innate immunity factors in vaccination with influenza vaccine, we conducted clinical and immunological examination of patients with chronic inflammat","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89618562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of posturographic indicators in children with non-purulent acute otitis media","authors":"I. Lozova","doi":"10.37219/2528-8253-2022-1-38","DOIUrl":"https://doi.org/10.37219/2528-8253-2022-1-38","url":null,"abstract":"Nowadays otitis media still remains one of the most common diseases of the middle ear in children [1]. The interconnection between otitis media and its effect on vestibular function in children has not been thoroughly studied yet.\u0000The aim of the study is to conduct a comparative analysis of stabilometric indicators of preschool children, diagnosed with non-purulent acute otitis media, and their relatively healthy typically developed peers.\u0000Materials and methods: 22 children, diagnosed with non-purulent acute otitis media, and their 25 relatively healthy typically developed peers aged 4 to 7, have been examined on the device \"MPFI Stabilograph 1\" (AS-TER IT, LLC, Kharkiv, Ukraine). The research has taken into account indicators of variation and shape of pressure center distribution, spectral-correlation indicators of stabilograms, as well as integral indicators of stability (length, velocity and angle of postural oscillations) and quality of equilibrium function in two sensory states (open and closed eyes). The obtained data have been calculated in the StabiliS software.\u0000Results: In children with non-purulent otitis, the coordinates of the pressure center are (7.04 [2.16 – 10.09]; -1.14 [-28.90 - 9.11]), and in the control group – (7.04 [3.30-16.16]; -13.72 [(-25.17) – (-10.30)]) with eyes closed. The average project ion figure of the pressure center in the sample with closed eyes is actually represented by a circle (ratio of Y / X axes = 0.98 [0.88; 1.14]) in non-purulent otitis media, and in the control group - an ellipse (Y / X axis ratio) = 1.16 [1.01; 1.33]). This indicates the lack of dominance of the ankle strategy to maintain posture in non-purulent otitis in the absence of visual control, and points to the presence of hidden vestibular disorders in non-purulent acute otitis media.\u0000Conclusion: The main result of our study is the discovery of the statistically significant decrease in the stability of the main posture and predictability of oscillatory movements in preschool children with acute nonpurulent otitis media compared with the control group only in the absence of visual control, i.e. in closed eyes. Also, statistically significant (p ≤ 0.05) differences have been found between children with acute non-purulent otitis media and control, namely the coefficient of equilibrium function only in the state with closed eyes. Decreased KFR values in children with non-purulent otitis indicate a decrease in the quality of postural control compared to control group.\u0000Given the almost asymptomatic nature of otitis media in preschool children, violations of postural control in non-purulent otitis media indicate the presence of latent vestibular disorders, which must be considered for the diagnosis and treatment of otitis media in children.","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"132 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79648974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Otological manifestation of vascular loops in a tertiary center in Malaysia: an 18-year experience","authors":"Shalini Ramasamy, J. Saniasiaya, Zainal A. ZAINAL ABDIN, Rosdan Salim","doi":"10.23736/s2724-6302.21.02297-9","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02297-9","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89551872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with moderate to severe pain during the first 24 hours after modified uvulopalatopharyngoplasty: a retrospective study","authors":"Nattaya Raykateeraroj, S. Chumpathong, Nuanprae Kitisin, Bharadee Teeravidja, W. Banhiran","doi":"10.23736/s2724-6302.20.02321-8","DOIUrl":"https://doi.org/10.23736/s2724-6302.20.02321-8","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87880283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The skull-vibration-induced nystagmus test in 10 points: our experience and a review of the literature","authors":"G. Dumas, C. Fabre, F. Perottino, P. Perrin, A. Albera, S. Schmerber","doi":"10.23736/s2724-6302.21.02346-8","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02346-8","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88529579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of osteomyelitis of the jaw due to Citrobacter freundii following odontogenic abscesses in a patient with breast cancer receiving bisphosphonates","authors":"F. Candelori, A. Colizza, M. Galli, A. Greco, M. Ralli, M. de Vincentiis","doi":"10.23736/s2724-6302.20.02309-7","DOIUrl":"https://doi.org/10.23736/s2724-6302.20.02309-7","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81722755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impaired central auditory processing in type 2 diabetes mellitus","authors":"M. Abou-Elew, M. Selim, Randa F. Salam, N. Hosni, Shaymaa M. Nassar","doi":"10.23736/s2724-6302.21.02339-0","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02339-0","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79542348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlations between oxygen saturation parameters and obstructive sleep apnea severity in unattended portable monitoring","authors":"Chuan Cheepcharoenrat","doi":"10.23736/s2724-6302.21.02376-8","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02376-8","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78515161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of low-grade mucoepidermoid carcinoma of the retromolar trigone","authors":"G. D’Erme, M. Galli, M. Ralli, Roger Altomari, A. Gilardi, F. Federici, M. Riminucci, A. Greco, A. Corsi, M. de Vincentiis","doi":"10.23736/s2724-6302.21.02386-0","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02386-0","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77015881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the DNA double helix to the epigenetics of deafness","authors":"A. Martini, Flavia Sorrentino","doi":"10.23736/s2724-6302.21.02347-x","DOIUrl":"https://doi.org/10.23736/s2724-6302.21.02347-x","url":null,"abstract":"","PeriodicalId":38742,"journal":{"name":"Otorhinolaryngology Clinics","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75604106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}