Interdisciplinary Neurosurgery: Advanced Techniques and Case Management最新文献

{"title":"Efficacy and safety of erythropoietin in patients with degenerative lumbar spinal stenosis undergoing multi-level lumbar interbody fusion: A case-control study","authors":"Dong Wang ,&nbsp;Ying Liu ,&nbsp;Shuang Cao ,&nbsp;Ying Wu ,&nbsp;Zhihao Ni ,&nbsp;Rende Ning","doi":"10.1016/j.inat.2025.102031","DOIUrl":"10.1016/j.inat.2025.102031","url":null,"abstract":"<div><div>Study Design.</div><div>Retrospective case-control study.</div></div><div><h3>Objective</h3><div>To assess the efficacy of short-term and high-dose application of erythropoietin (EPO) in patients with degenerative lumbar spinal stenosis (DLSS) undergoing multi-level lumbar interbody fusion (LIF) by assessing mean transfusion volume, transfusion rate, hematologic parameters, postoperative complications, and length of stay.</div><div>Summary of Background Data.</div><div>It has been reported to confirm the efficacy and safety of EPO in major surgeries like neurosurgery, cardiac surgery, and orthopedics. Still, there was little information on the application of EPO in patients with DLSS undergoing multi-level LIF.</div><div>Methods.</div><div>458 DLSS patients between January 2015 and December 2022 were selected and divided into EPO (group A), n = 112, and no EPO (group B), n = 105, according to treatment technique. Evaluation indexes included hemoglobin (Hb), hematocrit (Hct), red blood cells (RBC), postoperative complications, operative time, intraoperative bleeding, drainage volume, mean transfusion volume, transfusion rate, and length of stay.</div><div>Results.</div><div>The mean follow-up time was 21.7 months (18–24 months). Postoperative complications, surgical time, intraoperative bleeding, and drainage volume were not statistically different across groups. The Hb, Hct, and RBC values on postoperative days 1, 3, and 5 were significantly higher in group A than in B, and the difference was statistically significant (P &lt; 0.05). The mean transfusion rate was significantly lower in group A than in B (P &lt; 0.001). The mean transfusion volume was significantly lower in group A than in B (P &lt; 0.001). The length of stay was significantly lower in group A than in B (<em>P</em> &lt; 0.001).</div><div>Conclusion.</div><div>Short-term and high-dose perioperative EPO in DLSS patients undergoing multi-level LIF improves anemia-related hematologic parameters, reduces transfusion requirements, and shortens hospital stay without increasing deep vein thrombosis or wound infection.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102031"},"PeriodicalIF":0.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical management of ruptured intracranial arachnoid cysts in young adults: the role of subduroperitoneal shunt placement","authors":"Fassl Verena ,&nbsp;Sebök Martina ,&nbsp;Fierstra Jorn ,&nbsp;Krayenbühl Niklaus ,&nbsp;Regli Luca ,&nbsp;Velz Julia","doi":"10.1016/j.inat.2025.102023","DOIUrl":"10.1016/j.inat.2025.102023","url":null,"abstract":"<div><h3>Introduction</h3><div>Intracranial arachnoid cysts (IAC) are a common incidental finding on brain MRIs in adults. While IAC rupture, leading to severe intracranial hypertension, is well-documented in children, it is rarely reported in adults. As a result, there is limited guidance on managing ruptured IACs in young adults.</div><div>In particular, there is no data on the benefits of subduroperitoneal (SDP) shunt placement without interposed pressure valves in young adult patients, a treatment often used in pediatric patients.</div></div><div><h3>Methods</h3><div>We present two cases of young adult patients presenting with ruptured IAC with subsequent subdural hematoma/collection and consecutive neurological decline. Based on these sample clinical cases, we will discuss the above-mentioned management strategy and provide an overview of the current available literature.</div></div><div><h3>Results</h3><div>This case series demonstrates the successful management of ruptured IAC in young adults through drainage of subdural fluid collections via burr hole trepanation, combined with SDP shunt placement without interconnected pressure valves.</div></div><div><h3>Conclusion</h3><div>While there is general consensus that surgery is necessary for symptomatic cases following IAC rupture, the optimal approach remains debated. We provide additional evidence that burr hole trepanation combined with SDP shunt placement without interconnected pressure valves, a method commonly used in children, is a safe treatment option for young adults with ruptured IAC.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102023"},"PeriodicalIF":0.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of stimulation frequency on quality of speech in individuals with Parkinson’s disease who have undergone sub thalamic nucleus Deep Brain Stimulation surgery","authors":"Radhakrishnan Chella Perumal ,&nbsp;Krishnaswamy Visvanathan ,&nbsp;Sharon Mizpah Prathana Charan","doi":"10.1016/j.inat.2025.102034","DOIUrl":"10.1016/j.inat.2025.102034","url":null,"abstract":"<div><h3>Background</h3><div>Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) has been successful in improving the core motor symptoms, including motor fluctuations and speech systems, even in advanced stages of Parkinson’s Disease (PD). Given that the DBS frequency setting influences speech intelligibility, it is important to determine the ideal frequency setting while programming DBS to minimize reduction in speech quality postoperatively in individuals with PD.</div></div><div><h3>Aim</h3><div>To compare and contrast the effects of stimulation frequency (High, Low, DBS off state) in subthalamic nucleus Deep Brain Stimulation (STN-DBS) on the quality of speech in individuals with PD.</div></div><div><h3>Method</h3><div>Subjective and objective measures of articulation and voice parameters were estimated in low as well as high stimulation frequencies and the DBS-off state for six individuals with PD treated with STN-DBS.</div></div><div><h3>Results</h3><div>Friedman’s Two-way ANOVA yielded significant differences in objective measures of voice (<em>p</em> &lt; 0.05) only, however there was no statistically significant difference between the low, high stimulation frequency and DBS off state on the articulatory and subjective voice parameters.</div></div><div><h3>Conclusion</h3><div>The site of DBS insertion in the STN, the spread of current to adjacent pathways during high-frequency stimulation, the duration of disease, and the dosage of medication post-DBS surgery can cause detrimental effects on the quality of speech compared to motor movements. Low-frequency stimulation can improve speech scores, but it may also lead to a decline in motor function. On the contrary, a high stimulation frequency is effective in controlling tremors and body movements but may result in a decrease in speech scores. The extent of speech deterioration caused by a high stimulation frequency varies among patients, emphasizing the need for individualized programming of deep brain stimulation (DBS) parameters along with holistic rehabilitation for speech to balance motor and speech outcomes.</div></div><div><h3>Key messages</h3><div>Changes in the DBS stimulation frequency can alter speech and motor characteristics in individuals with Parkinson’s disease. Hence, while programming DBS stimulation parameters, it needs to be tailored to the individual patient’s needs, balancing the motor function with speech outcomes.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102034"},"PeriodicalIF":0.4,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary melanoma in the pineal gland: Differentiating primary from metastatic melanoma in the central nervous system","authors":"Denesh Selvarajah ,&nbsp;Hana Angelia Kawatu ,&nbsp;Peter Mews ,&nbsp;Elizabeth C Paver","doi":"10.1016/j.inat.2025.102028","DOIUrl":"10.1016/j.inat.2025.102028","url":null,"abstract":"<div><div>Primary melanoma of the pineal gland is exceedingly rare. Melanoma in the central nervous system (CNS) is far more likely to be a metastasis from a cutaneous primary; however, in a patient with no known history of melanoma, differentiating metastatic from primary CNS melanoma may present a diagnostic challenge. The distinction is important, however, as there are significant differences in tumour biology, prognosis, and responses to treatment. This report describes a rare case of solitary melanoma of the pineal gland in a 75-year-old female with no known history of melanoma and was considered as most likely to be a metastatic melanoma of unknown primary based on molecular testing of the tumour. This case highlights the utility of extended panel molecular testing in differentiating metastatic melanoma of unknown primary from primary CNS melanoma and the scarcity of evidence in the literature to guide the treatment in this setting.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102028"},"PeriodicalIF":0.4,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative developments in deep brain stimulation devices","authors":"Della Torre Attilio ,&nbsp;La Torre Domenico ,&nbsp;Guzzi Giusy ,&nbsp;Volpentesta Giorgio ,&nbsp;Lavano Angelo","doi":"10.1016/j.inat.2025.102035","DOIUrl":"10.1016/j.inat.2025.102035","url":null,"abstract":"<div><div>Technological advances in DBS hardware and software represent a significant growth area in functional neurosurgery. These advancements have the potential to significantly enhance treatment outcomes and expand the scope of neurological disorders that can be effectively addressed through DBS interventions. The advent of directional deep brain stimulation (DBS) ushers in a new era in neuromodulation, providing enhanced benefits to individuals with Parkinson’s disease, optimizing clinical outcomes more efficiently, and targeting treatment for stubborn symptoms using data-driven approaches. Implementing a multimodal programming strategy and incorporating cutting-edge current fractionation technology and image-guided tools for lead localization and brain sensing reduces reliance on traditional trial-and-error programming methods. This paves the way for a more predictive application of this therapy. These advancements are poised to propel the development of advanced closed-loop stimulation systems that seamlessly integrate continuous data streams, ultimately leading to improved patient care.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102035"},"PeriodicalIF":0.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of endoscopic surgery for treating spontaneous cerebrospinal fluid rhinorrhea","authors":"Saleh Rasras ,&nbsp;Soheila Nikakhlagh ,&nbsp;Hosein Safari ,&nbsp;Zahra Cheraghian ,&nbsp;Shohreh Noroozi","doi":"10.1016/j.inat.2025.102033","DOIUrl":"10.1016/j.inat.2025.102033","url":null,"abstract":"<div><h3>Background and Objective</h3><div>Spontaneous Cerebrospinal Fluid (CSF) rhinorrhea is a rare but potentially serious condition characterized by the leakage of CSF through the nasal cavity without an apparent traumatic or iatrogenic cause.</div></div><div><h3>Materials and Methods</h3><div>The current study was a five-year retrospective cross-sectional study on 24 patients with a history of spontaneous Cerebrospinal Fluid (CSF) rhinorrhea who underwent endoscopic surgery. The patients were selected among 90 individuals with CSF leaks.The required information was extracted from their medical records. The collected data included patient demographics, BMI, presenting symptoms, radiologic imaging findings, defect site, materials used for skull base repair, postoperative complications, and the success rate of endoscopic treatment.</div></div><div><h3>Results</h3><div>The patients who experienced spontaneous Cerebrospinal Fluid (CSF) leaks were primarily obese, middle-aged women. All patients presented with intermittent watery rhinorrhea, and 25% experienced positional headaches. Computed Tomography (CT) and magnetic resonance imaging (MRI) identified leak sites in 20 patients (83.3%). In cases where CT and MRI were inconclusive, CT cisternography was used (16.6%). The most common intraoperative defect site was the fovea ethmoidalis (50%). In 30% of patients, a single-layer reconstruction with only a fat graft was performed. Postoperative complications were observed in five patients (20%). Two patients developed meningitis postoperatively, which resolved with antibiotic treatment, and three patients experienced complete and permanent anosmia. Successful primary repair was achieved in 23 patients (96%), with a relapse rate of 4%.</div></div><div><h3>Conclusion</h3><div>Endoscopic surgery had a high success rate (96%) for the repair of spontaneous CSF rhinorrhea, with minimal recurrence (4%). The technique, particularly the multilayer approach, was effective in managing this condition.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102033"},"PeriodicalIF":0.4,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growing teratoma syndrome arising from malignant mixed germ cell tumor: Case report and review of literature","authors":"Kazumasa Senju ,&nbsp;Toshiyuki Enomoto ,&nbsp;Hiromasa Kobayashi ,&nbsp;Koichirou Takemoto ,&nbsp;Takashi Morishita ,&nbsp;Mikiko Aoki ,&nbsp;Makoto Hamasaki ,&nbsp;Hiroshi Abe","doi":"10.1016/j.inat.2025.102030","DOIUrl":"10.1016/j.inat.2025.102030","url":null,"abstract":"<div><div>Growing teratoma syndrome (GTS) is a condition in which tumor markers normalize during chemoradiation of germ cell tumors, but metastatic or recurrent lesions increase, and the lesions are histopathologically composed of mature teratomas. The incidence of GTS among intracranial germ cell tumors is estimated to be 5 %, making it a relatively rare condition. Here, we describe the case of an 8-year-old female with GTS 1.5 months after initial surgery. A suprasellar tumor was identified, and an endoscopic biopsy was performed. It was a mixed germ cell tumor, consisting mainly of immature teratomas, germinomas, and choriocarcinomas. After chemotherapy, both alpha-fetoprotein (AFP) and beta human chorionic gonadotropin decreased, but the suprasellar tumor grew rapidly and hydrocephalus developed. A craniotomy was performed, and the tumor was completely removed. Histopathological examination revealed that the tumor was a mature teratoma. A teratoma component has been identified in most biopsy specimens of mixed germ cell tumors that produce GTS. However, in some cases, GTS occurred even when teratomas were not detected in the biopsy specimens. As biopsies do not reflect the entire tumor histology, it is important to consider the possibility of conversion to GTS in cases of elevated AFP levels or imaging findings suspicious for teratoma, even in cases where the specimen does not contain a teratoma.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102030"},"PeriodicalIF":0.4,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors and treatment strategies for hyponatremia following aneurysm clipping in patients with aneurysmal subarachnoid hemorrhage: A Single Center experience","authors":"Kun Dai,&nbsp;Chengyuan Ji,&nbsp;Wei Wang,&nbsp;Pengfei Xia","doi":"10.1016/j.inat.2025.102032","DOIUrl":"10.1016/j.inat.2025.102032","url":null,"abstract":"<div><h3>Background</h3><div>Hyponatremia is one of the most common complications following aneurysmal subarachnoid hemorrhage (aSAH). This condition can exacerbate secondary injuries, such as cerebral edema, thereby leading to increased intracranial pressure and adversely affecting patient outcomes.</div></div><div><h3>Methods</h3><div>This study aims to investigate the factors associated with hyponatremia in patients following aSAH and to evaluate effective treatment strategies. We conducted a retrospective analysis of clinical data from 102 patients with aSAH. Based on the presence or absence of hyponatremia post-hemorrhage, patients were categorized into a hyponatremia group and a normonatremic group. Statistical analyses were performed on variables including gender, age, aneurysm location, Hunt-Hess grade, presence of hydrocephalus, duration of surgery, intraoperative blood loss, and postoperative lumbar cistern drainage. Treatment strategies were tailored according to the type of hyponatremia, distinguishing between Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) and Cerebral Salt-Wasting Syndrome (CSWS).</div></div><div><h3>Results</h3><div>Among 102 patients with aSAH, 40 cases developed hyponatremia. Through the implementation of appropriate treatment regimens, hyponatremia was successfully resolved in all affected patients. Univariate analysis revealed that the location of the aneurysm, Hunt-Hess grade, the presence of hydrocephalus, and lumbar cistern drainage were significant factors influencing postoperative hyponatremia. In contrast, variables such as sex, age, duration of surgery, and intraoperative blood loss were not statistically significant. Further analysis identified that aneurysms located in the anterior cerebral artery and anterior communicating artery, Hunt-Hess grade Ⅲ-IV, and the presence of hydrocephalus were independent risk factors for the development of hyponatremia in patients with aneurysmal SAH.</div></div><div><h3>Conclusion</h3><div>Patients with aSAH are particularly susceptible to developing hyponatremia. This risk is notably higher among individuals with aneurysms located in the anterior communicating artery or anterior cerebral artery, those presenting with high Hunt-Hess grade, or those with concurrent hydrocephalus. For such patients, vigilant monitoring and timely intervention are essential to mitigate the incidence of hyponatremia. Tailoring treatment strategies based on the specific subtype of hyponatremia can significantly improve clinical outcomes.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102032"},"PeriodicalIF":0.4,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant intra/extracranial facial nerve schwannoma: A case report and review of the literature","authors":"Bo Tan,&nbsp;Xiaohong Yin","doi":"10.1016/j.inat.2025.102029","DOIUrl":"10.1016/j.inat.2025.102029","url":null,"abstract":"<div><h3>Background</h3><div>Facial nerve schwannomas (FNSs) are rare, benign neoplasms arising from Schwann cells. While most FNSs are confined to the temporal bone or internal auditory canal, giant schwannomas extending across both intracranial and extracranial segments of the facial nerve are exceptionally rare and pose significant diagnostic and surgical challenges.</div></div><div><h3>Case presentation</h3><div>We report a 51-year-old woman with a 10-year history of progressive right-sided facial paralysis (House-Brackmann grade VI) and profound hearing loss. Imaging revealed a large, heterogeneous mass involving the right middle cranial fossa, external auditory canal, and mastoid, with destruction of adjacent bony structures. Electrophysiological studies confirmed severe facial nerve dysfunction. A combined subtemporal and mastoid approach enabled total tumor resection. Histopathology confirmed a WHO grade I schwannoma with strong S100, SOX10, and H3K27me3 positivity.</div></div><div><h3>Conclusion</h3><div>This case highlights the importance of integrating advanced neuroimaging, electrophysiological studies, and meticulous surgical planning in the management of extensive FNSs. Early diagnosis and timely intervention contribute to favorable outcomes, although functional recovery may require prolonged rehabilitation.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102029"},"PeriodicalIF":0.4,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of vacuum sign surgery for the inner recess of lumbar spinal canal","authors":"Xu Zhai ,&nbsp;Ye Youchen ,&nbsp;Jie Zheng","doi":"10.1016/j.inat.2025.102027","DOIUrl":"10.1016/j.inat.2025.102027","url":null,"abstract":"<div><div>The formation of intervertebral disc vacuum sign can be observed in late stage degenerative changes of the lumbar disc. In 1937, Magnusson first proposed intervertebral disc vacuum sign, which refers to the accumulation of gas caused by disc dehydration and fissure formation during the degenerative process of the lumbar disc. The vacuum phenomenon can occur around the articular processes, within the spinal canal, and in the intervertebral disc, with the most common being in the intervertebral disc. The vacuum phenomenon causes the mechanical receptors, injury receptors, and pressure receptors around the intervertebral disc to react more strongly than usual, thereby increasing lower back pain. A small amount of vacuum phenomenon can also occur in the spinal canal and lateral recess, inducing lower limb numbness and pain, which needs to be distinguished from sciatica caused by intervertebral disc herniation. This article presents a case of vacuum syndrome in the inner recess of the lumbar spinal canal, which underwent surgical treatment and achieved good therapeutic effects. And the characteristics, diagnosis, and treatment of lumbar vacuum sign were discussed.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102027"},"PeriodicalIF":0.4,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}