Interdisciplinary Neurosurgery: Advanced Techniques and Case Management最新文献

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Endovascular, microsurgical and combined treatment of cerebral arteriovenous malformations: A retrospective single-center study 脑动静脉畸形的血管内、显微外科及联合治疗:一项回顾性单中心研究
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-07-05 DOI: 10.1016/j.inat.2025.102097
Camilla S. Kristiansen, Michelle J. Nielsen, Bjarni Jóhannsson, Sune Munthe, Anders E. Schack, Jakob H. Arngrim, Troels H. Nielsen
{"title":"Endovascular, microsurgical and combined treatment of cerebral arteriovenous malformations: A retrospective single-center study","authors":"Camilla S. Kristiansen, Michelle J. Nielsen, Bjarni Jóhannsson, Sune Munthe, Anders E. Schack, Jakob H. Arngrim, Troels H. Nielsen","doi":"10.1016/j.inat.2025.102097","DOIUrl":"10.1016/j.inat.2025.102097","url":null,"abstract":"","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102097"},"PeriodicalIF":0.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of the prevalence of spinal lesions in neurofibromatosis type 1 in Manchester, United Kingdom 英国曼彻斯特1型神经纤维瘤病脊柱病变患病率的综述
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-07-05 DOI: 10.1016/j.inat.2025.102088
Moska Sial, K. Joshi George
{"title":"A review of the prevalence of spinal lesions in neurofibromatosis type 1 in Manchester, United Kingdom","authors":"Moska Sial,&nbsp;K. Joshi George","doi":"10.1016/j.inat.2025.102088","DOIUrl":"10.1016/j.inat.2025.102088","url":null,"abstract":"<div><h3>Objective</h3><div>Neurofibromatosis type 1 (NF1) is a tumour syndrome known to have significant life altering manifestations; one such major manifestation is spinal lesions. Much of the published literature on NF1 comes from large dedicated NF1 centres which receive patients from a wide non defined geographic area. This makes it difficult to work out the prevalence of a particular disease in a defined population. This is a retrospective clinical review that investigates the prevalence of spinal lesions in NF1 patients in a defined geographical location.</div></div><div><h3>Methods</h3><div>The data was collected over a period of 5 years from a cohort of 73 patients; each patient had a complete diagnosis of NF1 and resided in Manchester, United Kingdom, at the time of the study. This data was collected from multidisciplinary team meeting reports, with included spinal radiological reports investigating 20 variables related to any spinal disease associated with NF1.</div></div><div><h3>Results</h3><div>Spinal nerve root tumours were found in 51 % of patients in this cohort, the most common spinal region being the cervical spine; 60 % of the total number of patients with spinal nerve root tumours had C2 spinal nerve root tumours. Spinal deformity was present in 60 % of patients in this cohort. The most common spinal deformity in this cohort was scoliosis, where 91 % of these patients with spinal deformities had scoliosis.</div></div><div><h3>Conclusion</h3><div>This is the first reported study to publish data on the prevalence of known spinal lesions in NF1 individuals from a defined geographical location. This review aims to aid current clinical practice in the management of NF1, as well as fill the gap in the current NF1 literature.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102088"},"PeriodicalIF":0.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beta-blocker combined with alpha-2 agonist in patients with severe aneurysmal subarachnoid hemorrhage: A single-center retrospective observational study -受体阻滞剂联合α -2激动剂治疗严重动脉瘤性蛛网膜下腔出血:一项单中心回顾性观察研究
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-26 DOI: 10.1016/j.inat.2025.102077
Xiaoyu Gao , Yanru Zhao , Junjie Tian , Haorun Wang , Liangnan Zeng , Tangming Peng , Ligang Chen , Shan Zeng
{"title":"Beta-blocker combined with alpha-2 agonist in patients with severe aneurysmal subarachnoid hemorrhage: A single-center retrospective observational study","authors":"Xiaoyu Gao ,&nbsp;Yanru Zhao ,&nbsp;Junjie Tian ,&nbsp;Haorun Wang ,&nbsp;Liangnan Zeng ,&nbsp;Tangming Peng ,&nbsp;Ligang Chen ,&nbsp;Shan Zeng","doi":"10.1016/j.inat.2025.102077","DOIUrl":"10.1016/j.inat.2025.102077","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background and aim&lt;/h3&gt;&lt;div&gt;Excessive sympathetic nerve system (SNS) activation played a key role in the pathophysiology of acute brain injury, which was also named stress response. Aneurysmal subarachnoid hemorrhage (aSAH), as one type of acute brain injury, was a worldwide primary life-threatening disease. It’s reported that beta-blocker or alpha-2 agonist could alleviate the stress response in acute injury, respectively. The present study aimed to investigate the safety and effectivity of the stress-reducing therapy in patients with severe aSAH using the bundle of beta-blocker combined with alpha-2 agonist.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;The retrospective, observational study consecutively collected ninety-nine patients with severe aSAH in our center (single center) from December 2019 to September 2023. These patients were divided into the stress-reducing therapy (SRT) group and no stress-reducing therapy (nSRT) group according to whether they obtained stress-reducing therapy. Accordingly, there are sixty-three patients in SRT group and thirty-six in nSRT group. Variables related to population, consciousness, heart rate, respiratory rate, systolic pressure, diastolic pressure, sodium ion (Na+), aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine (Cr), glomerular filtration rate (GFR), temperature, blood sugar, white blood cell (WBC), albumin (ALB), prealbumin (p-ALB), and hospital costs, length of stay in the hospital, length of stay in neurosurgical intensive care unit (NICU), and Glasgow outcome scale (GOS) were recorded and analyzed on the third, seventh and tenth day in all patients, respectively.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Catecholamine significantly increased in all patients in the stress-reducing therapy (SRT) group and no stress-reducing therapy (nSRT) groups at admission. The consciousness (&lt;em&gt;P&lt;/em&gt; = 0.007), heart rate (&lt;em&gt;P&lt;/em&gt; = 0.004), respiratory rate (&lt;em&gt;P&lt;/em&gt; = 0.001), Cr (&lt;em&gt;P&lt;/em&gt; = 0.011), temperature (&lt;em&gt;P&lt;/em&gt; = 0.000) and blood sugar (&lt;em&gt;P&lt;/em&gt; = 0.003) were statistically different between groups on the third day of admission. The consciousness (&lt;em&gt;P&lt;/em&gt; = 0.003), Na+ (&lt;em&gt;P&lt;/em&gt; = 0.000) were statistically different between groups on the seventh day of admission. The onsciousness (&lt;em&gt;P&lt;/em&gt; = 0.009), respiratory rate (&lt;em&gt;P&lt;/em&gt; = 0.031), systolic pressure (&lt;em&gt;P&lt;/em&gt; = 0.000), diastolic pressure (&lt;em&gt;P&lt;/em&gt; = 0.020), Cr (&lt;em&gt;P&lt;/em&gt; = 0.002), temperature (&lt;em&gt;P&lt;/em&gt; = 0.000), GFR (&lt;em&gt;P&lt;/em&gt; = 0.012) and ALB (&lt;em&gt;P&lt;/em&gt; = 0.003) were statistically different between groups on the tenth day of admission. Compared with the nSRT group, patients in the SRT group had abetter outcome at discharge (&lt;em&gt;GOS&lt;/em&gt;, &lt;em&gt;P&lt;/em&gt; = 0.012).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;In the present study, catecholamine of the patients with severe aSAH was significantly increased at admission, showing that excessive SNS activation occurred in patients with onset of severe aSAH ictus","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102077"},"PeriodicalIF":0.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebellopontine angle epidermoid cyst: Case report and review of outcomes and embryological pathogenesis 桥小脑角表皮样囊肿:病例报告、结果和胚胎发病机制回顾
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-24 DOI: 10.1016/j.inat.2025.102082
Cameron Ehsan BS , Justin Falk DO , Ali Chahlavi MD
{"title":"Cerebellopontine angle epidermoid cyst: Case report and review of outcomes and embryological pathogenesis","authors":"Cameron Ehsan BS ,&nbsp;Justin Falk DO ,&nbsp;Ali Chahlavi MD","doi":"10.1016/j.inat.2025.102082","DOIUrl":"10.1016/j.inat.2025.102082","url":null,"abstract":"<div><div>Cerebellopontine angle (CPA) epidermoid cysts are rare, benign lesions that remain diagnostically and surgically challenging. We present the case of a 53-year-old man with progressive unilateral hearing loss, headache, vertigo, tremor, and gait incoordination. MRI revealed a multiloculated, diffusion-restricting CPA mass. The patient underwent retrosigmoid microsurgical resection and gross total resection was achieved. Postoperative recovery was uncomplicated and histopathology confirmed an epidermoid cyst. We contextualize this case within the context of the literature. Complete resection offers the lowest recurrence rates while subtotal excision portends up to a seven-fold increase in recurrence. New cranial nerve deficits represent the most common complications. Long-term surveillance is essential because recurrences can present decades later. Pathogenetically, epidermoids arise from ectodermal rests sequestered during neural tube closure. Recent work may implicate dysregulated developmental transcription factors in maintaining an epidermal phenotype within neural tissue. Aberrant expression of such factors in dorsal ectoderm may hinder full neural differentiation, allowing cutaneous inclusions to persist and later form cysts. Early recognition via MRI, microsurgical technique balancing total removal with neurological safety, and follow-up are pivotal to optimizing outcomes and quality of life for patients with CPA epidermoid cysts.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102082"},"PeriodicalIF":0.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Size ratio as a predictor of recanalization in anterior communicating artery aneurysms post-endovascular treatment 大小比作为前交通动脉瘤血管内治疗后再通的预测因子
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-22 DOI: 10.1016/j.inat.2025.102076
Yong Zheng , Dongtao Liu , Xiangke Ma , Yue Gao , Yang Zhou , Weihua Jia
{"title":"Size ratio as a predictor of recanalization in anterior communicating artery aneurysms post-endovascular treatment","authors":"Yong Zheng ,&nbsp;Dongtao Liu ,&nbsp;Xiangke Ma ,&nbsp;Yue Gao ,&nbsp;Yang Zhou ,&nbsp;Weihua Jia","doi":"10.1016/j.inat.2025.102076","DOIUrl":"10.1016/j.inat.2025.102076","url":null,"abstract":"<div><h3>Objective</h3><div>Many studies have found that some morphological parameters of aneurysms, such as the size ratio (SR), were associated with ruptured aneurysm. However, few studies have confirmed the relationship between aneurysm parameters and recurrence after endovascular treatment (EVT). This study aimed to determine the risk factors for recurrence of anterior communicating artery aneurysm (ACoAA), the clinical outcomes, and perioperative complications following endovascular treatment.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed data from patients with ACoAA treated with EVT, including both ruptured and unruptured aneurysms. Morphological characteristics of the aneurysms and the diameter of their parent vessels were evaluated utilizing two and three-dimensional digital subtraction angiography (DSA), which included Height, Dome width, Maximum height, Neck width, Parent artery diameter, Dome-to-neck ratio, and SR. Clinical and angiographic data were collected at baseline and follow-up.</div></div><div><h3>Results</h3><div>A total of 51 patients were included, including 24 coil embolization patients, 18 stent assisted coil embolization (SAC) patients, and 9 balloon assisted coil (BAC) embolization patients. The median follow-up time was 9.6 months, with a major recanalization rate of 6.4 % (3 out of 47 cases). No adverse events occurred in the 3 patients with major recanalization after retreatment. Multivariate analysis showed that SR was an independent risk factor for aneurysm recanalization (OR, 7.236; 95 % CI, 1.770–29.587; p = 0.006). Good clinical outcomes were observed in 44 patients (86.3 %). High Hunt and Hess grade on admission was significantly associated with poor outcomes (OR, 11.609; 95 % CI, 1.677–80.365; p = 0.013). 6 (11.8 %) patients experienced perioperative complications.</div></div><div><h3>Conclusions</h3><div>SR is a reliable morphological parameter for predicting recanalization risk of ACoAA after EVT. Given the increased risk of rebleeding and the low risk of retreatment, patients with major recanalization should undergo additional treatment.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102076"},"PeriodicalIF":0.4,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Large anterior communicating artery aneurysm successfully obliterated by straightening the parent artery: an illustrative case 通过矫直载动脉成功消除大前交通动脉瘤:一个说明性病例
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-19 DOI: 10.1016/j.inat.2025.102081
Kengo Yamada , Masashi Kotsugi , Ryosuke Maeoka , Hiromichi Hayami , Tomoya Okamoto , Yoshiaki Kakehi , Ryosuke Matsuda , Ichiro Nakagawa
{"title":"Large anterior communicating artery aneurysm successfully obliterated by straightening the parent artery: an illustrative case","authors":"Kengo Yamada ,&nbsp;Masashi Kotsugi ,&nbsp;Ryosuke Maeoka ,&nbsp;Hiromichi Hayami ,&nbsp;Tomoya Okamoto ,&nbsp;Yoshiaki Kakehi ,&nbsp;Ryosuke Matsuda ,&nbsp;Ichiro Nakagawa","doi":"10.1016/j.inat.2025.102081","DOIUrl":"10.1016/j.inat.2025.102081","url":null,"abstract":"<div><h3>Background</h3><div>Endovascular devices for cerebral aneurysms have advanced, but large aneurysms with complex shapes remain difficult to cure. A steep branching angle for the parent artery can be a key factor in recurrence after endovascular treatment. We report a case in which a large anterior communicating artery (Acom) aneurysm (left A1–A2 junction) with a hairpin-shaped parent artery was completely occluded by straightening the parent artery using a neck-bridging stent.</div></div><div><h3>Case description</h3><div>The patient in his 60 s was referred to our department after cerebral magnetic resonance imaging (MRI) in a dementia evaluation revealed a large Acom aneurysm 20 mm in diameter. Initial coil embolization was successful, but recurrence was observed six months later, requiring retreatment. After embolizing the recurrent aneurysm, a neck-bridging stent was placed in the left A1–A2 segment with a hairpin curve, successfully straightening the parent artery. The postoperative course was uneventful, with no hemorrhagic or ischemic complications, and the patient was discharged independently. No recurrence was observed on MRI a year later.</div></div><div><h3>Conclusion</h3><div>This successful use of a neck-bridging stent to straighten angulation of the parent artery in refractory large Acom aneurysms suggests a potential method for preventing aneurysm recurrence.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102081"},"PeriodicalIF":0.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144338885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analyzing the root causes of neurosurgery complaints: a case study of 5 complaints 神经外科主诉原因分析:以5例主诉为例
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-19 DOI: 10.1016/j.inat.2025.102078
Bahram Aminmansour , Hamed Shoaee , Vahid Moghtader , Niloufar Talebi Meimand , Donya Sheibani Tehrani
{"title":"Analyzing the root causes of neurosurgery complaints: a case study of 5 complaints","authors":"Bahram Aminmansour ,&nbsp;Hamed Shoaee ,&nbsp;Vahid Moghtader ,&nbsp;Niloufar Talebi Meimand ,&nbsp;Donya Sheibani Tehrani","doi":"10.1016/j.inat.2025.102078","DOIUrl":"10.1016/j.inat.2025.102078","url":null,"abstract":"<div><h3>Introduction</h3><div>By the end of 2022, the amount of medical malpractice has increased by 11.8% compared to the previous year, of which 46.6% have resulted in a conviction. Considering the importance of this issue, the present study aimed to determine the frequency of medical errors in the field of neurosurgery during the last five years.</div></div><div><h3>Method</h3><div>The present study was a cross-sectional descriptive study. The statistical population included 5 cases of patient complaints against neurosurgeons, which were analyzed.</div></div><div><h3>Results</h3><div>The results of this study showed that communication between doctor and patient is an inseparable part of the process of reducing complaints from doctors.</div></div><div><h3>Conclusion</h3><div>Based on the results of this study, it is suggested that the attending physician should provide clear justification to the patients, and more attention should be paid to the issue of communication between the physician and the patient.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102078"},"PeriodicalIF":0.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of flow diverters for the treatment of symptomatic dissections of the cervical segment of the internal carotid artery 血流分流器治疗颈内动脉颈段症状性夹层的疗效观察
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-19 DOI: 10.1016/j.inat.2025.102080
Yu Zhang , Xufeng Sun , Yueyang Peng , Mengyuan Zhang , Zhifeng Wen
{"title":"Efficacy of flow diverters for the treatment of symptomatic dissections of the cervical segment of the internal carotid artery","authors":"Yu Zhang ,&nbsp;Xufeng Sun ,&nbsp;Yueyang Peng ,&nbsp;Mengyuan Zhang ,&nbsp;Zhifeng Wen","doi":"10.1016/j.inat.2025.102080","DOIUrl":"10.1016/j.inat.2025.102080","url":null,"abstract":"<div><div>Internal carotid artery dissection is a relatively uncommon cerebrovascular condition that can result in neck pain, vascular stenosis, and acute stroke, particularly in young and middle-aged individuals. Vascular treatments have demonstrated potential in addressing this condition; however, the use of carotid artery stents often encounters difficulties in areas near the skull base or within tortuous vessels. Flow Diverter (FD) devices, known for their superior support and flexibility, have emerged as an innovative endovascular treatment. Despite their promise, reports on their use in cases of internal carotid artery dissection remain limited. This article discusses two cases in which FD devices were employed to treat dissections in the upper and middle segments of the C1 internal carotid artery, achieving favorable outcomes during long-term follow-up. These findings suggest that FD treatment for internal carotid artery dissection is both safe and effective, representing a feasible therapeutic option.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102080"},"PeriodicalIF":0.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Midbrain radiation-induced cavernous malformation after treatment for Pontine Glioma: A case report 脑桥神经胶质瘤治疗后中脑放射诱导海绵状畸形1例
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-19 DOI: 10.1016/j.inat.2025.102079
Rong-Tse Hsu , Hung-Lin Lin , Ji-An Liang
{"title":"Midbrain radiation-induced cavernous malformation after treatment for Pontine Glioma: A case report","authors":"Rong-Tse Hsu ,&nbsp;Hung-Lin Lin ,&nbsp;Ji-An Liang","doi":"10.1016/j.inat.2025.102079","DOIUrl":"10.1016/j.inat.2025.102079","url":null,"abstract":"<div><h3>Background</h3><div>Adult brainstem gliomas are rare tumors, with concurrent radiation therapy (RT) and temozolomide being the standard treatment approach. Another uncommon condition, adult brainstem radiation-induced cavernous malformation (RICM), presents a significant risk of hemorrhage and focal neurological deficits. While surgery is typically recommended for symptomatic RICM, its location in the brainstem makes the procedure riskier.</div><div>We report a case of a brainstem glioma treated with chemoradiation, followed by the development of a brainstem RICM 10 years later. The patient was monitored with routine imaging follow-ups, demonstrating stable clinical and radiographic findings.</div></div><div><h3>Case Description</h3><div>A 36-year-old woman experienced dizziness, unsteady gait, and paresthesia for 2–3 months. Brain magnetic resonance imaging (MRI) in October 2014 revealed an infiltrative brainstem tumor. Biopsy confirmed a WHO grade 3 anaplastic astrocytoma. The primary treatment consisted of concurrent RT, 56 Gray (Gy) over 28 fractions, along with temozolomide. Adjuvant temozolomide therapy was continued for 10 years. In October 2024, a follow-up MRI showed a new cavernous malformation (CM) in the midbrain. Owing to the patient’s stable neurological status, continued observation with imaging surveillance was chosen.</div></div><div><h3>Conclusions</h3><div>This case highlights our experience in treating adult brainstem glioma and brainstem RICM. There is no established consensus on the standard management for these uncommon conditions. The treatment strategies employed in our case appeared to contribute to favorable long-term survival for the brainstem glioma and short-term stable condition for the brainstem RICM. Further studies are necessary to develop a standardized approach to treating these rare diseases.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102079"},"PeriodicalIF":0.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally invasive surgical management of patients with cerebral hemorrhage after PCI and literature review 脑出血PCI术后的微创手术治疗及文献复习
IF 0.4
Interdisciplinary Neurosurgery: Advanced Techniques and Case Management Pub Date : 2025-06-18 DOI: 10.1016/j.inat.2025.102075
Xuanbo Luo, Dawei Zhao, Haoquan Wang, Kai Liu, Guosheng Shi, Wei Bu
{"title":"Minimally invasive surgical management of patients with cerebral hemorrhage after PCI and literature review","authors":"Xuanbo Luo,&nbsp;Dawei Zhao,&nbsp;Haoquan Wang,&nbsp;Kai Liu,&nbsp;Guosheng Shi,&nbsp;Wei Bu","doi":"10.1016/j.inat.2025.102075","DOIUrl":"10.1016/j.inat.2025.102075","url":null,"abstract":"<div><h3>Background</h3><div>Postoperative bleeding after percutaneous coronary intervention (PCI) is a major early mortality factor for patients, and cerebral haemorrhage is one of the most dangerous and serious one, and there is no effective treatment guideline and expert consensus for post-PCI cerebral haemorrhage.</div><div>Case presentation</div><div>The Third Hospital of Hebei Medical University admitted two patients with post-PCI cerebral haemorrhage from October 2023 to July 2024, and the patients were treated with minimally invasive drilling and drainage under stereotactic positioning. Past medical history showed that the patients underwent PCI, and preoperative CT confirmed acute cerebral haemorrhage, and the patients were treated with minimally invasive drilling and drainage under stereotactic positioning, and they recovered well after the operation.</div></div><div><h3>Conclusion</h3><div>For patients with large amount of cerebral haemorrhage or even cerebral herniation, the necessity of surgical treatment becomes more prominent. In the same time, Minimally invasive surgical management could take better prognosis for patients.</div><div>Percutaneous coronary intervention (PCI) is widely used in clinical practice, but a serious complication, bleeding, often occurs after PCI. Post-PCI bleeding is the most important factor in early death, and cerebral haemorrhage is the most dangerous and fatal one [<span><span>1</span></span>]. The choice of treatment for patients undergoing PCI is made difficult by the fact that they are often subjected to DAPT, which results in coagulation abnormalities and an elevated risk of haemorrhage. Usually, for patients with a small amount of cerebral haemorrhage, conservative medical treatment including nerve nutrition, dehydration to lower the cranial pressure, and prevention of cerebral vasospasm are given priority, but when a large amount of cerebral haemorrhage occurs or even cerebral herniation is formed in the patient, surgical treatment becomes an important and should be considered as a priority treatment modality, including craniectomy for haematoma removal and decompression of debridement flap, minimally invasive drilling and drainage under stereotactic positioning, and neuroendoscopic haematoma removal [<span><span>[2]</span></span>, <span><span>[3]</span></span>, <span><span>[4]</span></span>], there is no expert consensus or guideline for the treatment of these patients, this paper aims to discuss the choice of treatment options for these patients, and adopts two patients hospitalised in our hospital, using minimally invasive drilling and drainage under stereotactic positioning, the patients’ postoperative haematomas were better absorbed, and the prognosis was good, with no obvious neurological impairment left.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"41 ","pages":"Article 102075"},"PeriodicalIF":0.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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