Interdisciplinary Neurosurgery: Advanced Techniques and Case Management最新文献

{"title":"Multispecialty view on the management of basal transethmoidal encephaloceles and meningoceles in the neonate","authors":"Rose Fluss ,&nbsp;Anne Lally ,&nbsp;Jinu Kim ,&nbsp;Andrew J. Kobets","doi":"10.1016/j.inat.2025.102006","DOIUrl":"10.1016/j.inat.2025.102006","url":null,"abstract":"<div><div>Basal encephaloceles, and their subtype transethmoidal encephaloceles, are an extremely rare congenital abnormality. They commonly present with ocular anomalies and congenital dyscrasias. Similarly, meningoceles are unusual lesions associated with midfacial anomalies and hypertelorism. We report a case of a preterm newborn who was suspected to have a transethmoidal encephalocele who was operated on day 15 of life due to its expanding nature and concern for cerebrospinal fluid leak. Intraoperatively the lesion was isolated and noted to be devoid of brain tissue thus diagnosing her with a transethmoidal meningocele. Discussed here are the challenges faced with a neonatal repair of a transethmoidal meningocele and the multidisciplinary approach used involving neuroanesthesia, neurosurgery, plastic and reconstructive surgery, as well as otolaryngology teams.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102006"},"PeriodicalIF":0.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143683210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should neurosurgeons ‘chase the dragon’? A case report","authors":"Rick H.G.J. van Lanen ,&nbsp;Christianne M.C. Hoeberigs ,&nbsp;Verona C.A. Gerardu ,&nbsp;Roel H.L. Haeren","doi":"10.1016/j.inat.2025.102012","DOIUrl":"10.1016/j.inat.2025.102012","url":null,"abstract":"<div><h3>Purpose</h3><div>“Chasing the dragon” originally referred to the inhalation of vaporized heroin or opium, but it has since expanded to describe a condition affecting the brain. The term is associated with severe neurological complications, notably toxic leukoencephalopathy. Patients may present with acute neurological symptoms, including lowered consciousness and significant deficits.</div></div><div><h3>Case</h3><div>A 23-year-old male presented with a Glasgow Coma Scale score of E1M1V1 after prolonged unresponsiveness. Imaging showed cerebellar hypodensities, initially diagnosed as infarction with herniation. Immediate decompression of the posterior fossa was performed. Nevertheless, his clinical condition worsened and follow-up imaging revealed toxic leukoencephalopathy which was contributed to abuse of alcohol, quetiapine, 3-methylmethcathinone, cocaine and oxycodone, mimicking abnormalities seen in “chasing the dragon” syndrome. Additionally, severe systemic effects with multi-organ failure ensued, and treatment was withdrawn due to poor prognosis, resulting in the patient’s death.</div></div><div><h3>Conclusions</h3><div>“Chasing the dragon” −like toxic leukoencephalopathy is associated with severe neurological complications, resulting from widespread white matter damage. Our case showed typical imaging findings of drug-induced leukoencephalopathy after polysubstance abuse. Despite undergoing neurosurgical decompression, the outcome was fatal. This highlights the limited effectiveness of surgical intervention in such severe cases, emphasizing that neurosurgeons should not “chase the dragon”. It is essential to consider the differential diagnosis of CHANTER, where neurosurgical intervention, can play a role in improving outcomes.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102012"},"PeriodicalIF":0.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143683211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bertolotti Syndrome: Does it really exist? systematic review","authors":"Acevedo-Gonzalez Juan Carlos ,&nbsp;Delgado-Caicedo Mónica Gabriela ,&nbsp;Lacouture-Silgado Isabella","doi":"10.1016/j.inat.2025.102008","DOIUrl":"10.1016/j.inat.2025.102008","url":null,"abstract":"<div><h3>Study Design</h3><div>systematic review.</div></div><div><h3>Objectives</h3><div>Bertolotti syndrome is described as the association between low back pain and transitional abnormalities of the lumbosacral spine. This association is nonspecific and does not justify surgical procedures on this anomaly, even percutaneous or minimally invasive. We consider that congenital variations of the lumbosacral junction are elements that modify the normal biomechanics of the spine and favor the development of other painful pathologies already known. This work is a systematic review that aims to determine whether Bertolotti Syndrome should be considered as an independent etiology of low back pain or only as a risk factor (Lumbosacral transitional vertebrae) for developing biomechanical alterations that produce pain.</div></div><div><h3>Methods</h3><div>The search used the following terms (PubMed, Embase, Cochrane library and clinical trials): Bertolotti syndrome, low back pain, lumbosacral transitional vertebrae. The search covered the last 21 years (2013 to 2024). The “Rayyan” program was used to gather information and facilitate the analysis process. Each author reviewed the abstract of the articles found. Inclusion: Systematic reviews, clinical trials, observational studies, and case series. Exclusion: Theoretical articles, narrative reviews, and articles in languages other than English.</div></div><div><h3>Results</h3><div>Initial analysis: 285 articles were selected (PubMed-115, Scopus-76, Embase-94), 238 articles were excluded (due to duplicated articles or titles not meeting inclusion/exclusion criteria). 47 articles were selected (25 retrospective clinical studies, 12 case series, 3 randomized clinical trial, and 7 systematic reviews; <em>meta</em>-analyses were not found). The PRISMA checklist was applied, and each article were assessed using the STROBE and CONSORT checklists.</div></div><div><h3>Conclusions</h3><div>Low back pain in patients with congenital abnormalities of the lumbosacral junction requires extensive clinical and radiological evaluation to determine the cause of the source of symptoms. Transitional anomaly is only a risk factor that modifies the normal biomechanics of the lumbosacral spine and not the therapeutic target. Bertolotti syndrome is an anecdotal but not objective association of the origin of pain.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102008"},"PeriodicalIF":0.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transoral extrusion of ventriculoperitoneal shunt distal segment: A case report of very rare complication","authors":"Seare Halefom Kahsay ,&nbsp;Samson Yibalih Gebregergisse ,&nbsp;Yirgalem Teklebirhan Gereziher ,&nbsp;Berihu Tadishu Gebre","doi":"10.1016/j.inat.2025.102010","DOIUrl":"10.1016/j.inat.2025.102010","url":null,"abstract":"<div><h3>Background</h3><div>Ventriculoperitoneal shunts (VPS) are a widely utilized neurosurgical intervention for managing hydrocephalus of diverse etiologies. While generally a safe and well-established treatment approach, VPS procedures are not without potential complications. The most frequently reported issues include infection, obstruction, disconnection or fracture of the shunt hardware, as well as skin erosion and overdrainage and tip migration. Migration of VPS tip through various body cavities and openings is a rare but serious complication. Transoral extrusion of the distal segment of a VPS is an exceedingly uncommon complication with only 43 case reports in the literature.</div></div><div><h3>Observation</h3><div>We report a case of 2-year-old male pediatric patient presented with the extrusion of VPS distal tip through the oral cavity. The patient underwent thorough investigation including shunt series. The patient was optimized and empiric broad-spectrum antibiotic administration and was subsequently taken to the operating room for shunt revision. The patient had favorable surgical outcome.</div></div><div><h3>Conclusion</h3><div>Transoral migration of the distal VPS component is an uncommon yet serious complication following VPS placement. This complication is primarily observed in pediatric patients within the first year after the initial VPS procedure. Most instances can be addressed by removing the distal segment, either through the oral cavity or the abdomen. Subsequent management involves monitoring the patient for signs of peritonitis, central nervous system infection, and progression of the underlying hydrocephalus. Prompt antibiotic treatment is required for any identified infections, and the hydrocephalus is managed by either inserting a new VPS or replacing only the distal segment.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102010"},"PeriodicalIF":0.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic spinal cord herniation: A case report","authors":"Maryam Khaleghi Ghadiri,&nbsp;Özer Tokzös,&nbsp;Laura Horstick,&nbsp;Walter Stummer","doi":"10.1016/j.inat.2025.102011","DOIUrl":"10.1016/j.inat.2025.102011","url":null,"abstract":"<div><div>Spinal cord herniation (SCH) remains challenging to diagnose, and the progression of the disease is often poorly understood. This case report details a rare instance of posttraumatic SCH occurring 35 years after a severe traffic accident. The patient, a 51-year-old woman, presented with left leg paresis, altered temperature sensation, muscle spasticity, and thoracic pain. MRI revealed a pronounced herniation at the T1/T2 level. The surgical intervention involved adhesiolysis and dural repair, resulting in immediate clinical improvement, including enhanced gait and reduced pain. Postoperative MRI confirmed correct spinal cord relocating, with the patient showing ongoing recovery after nine months. This case represents the importance of recognizing delayed SCH as a potential long-term complication of spinal trauma and points out the benefits of surgical intervention for optimal recovery.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102011"},"PeriodicalIF":0.4,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awake craniotomy versus general anesthesia for resection of intra-axial brain tumors: A systematic review and meta-analysis","authors":"Mohammad Hamza Bajwa ,&nbsp;Nowal Hussain ,&nbsp;Muhammad Waqas Saeed Baqai ,&nbsp;Faiza Urooj ,&nbsp;Unaiza Naeem ,&nbsp;Syed Hasan Shuja ,&nbsp;Ali Hyder Nazeer ,&nbsp;Ahsan Ali Khan ,&nbsp;Syed Ather Enam ,&nbsp;Saqib Kamran Bakhshi","doi":"10.1016/j.inat.2025.102007","DOIUrl":"10.1016/j.inat.2025.102007","url":null,"abstract":"<div><h3>Background</h3><div>Awake craniotomy (AC) for intra-axial brain tumors is useful for preserving cortical and subcortical white matter tracts that may have tumor invasion. No specific guideline or concrete evidence exists regarding the superiority of AC over surgery under general anesthesia (GA), with many surgeons preferring resection under GA for benefits of potentially better extent of resection.</div></div><div><h3>Methods</h3><div>A systematic review and <em>meta</em>-analysis was conducted in accordance with PRISMA guidelines and registered on PROSPERO(CRD42022311131). A comprehensive search was conducted using specific keywords and MeSH terms with Boolean operators, from PubMED and Cochrane databases. Pooled effect size was estimated using a Mantel-Haenszel random-effects model, with evaluation of heterogeneity using Higgins <em>I²</em> statistic.</div></div><div><h3>Results</h3><div>Of 929 articles, ten were included for quantitative analysis. Selected studies included 1974 patients (681 in the AC group, 1293 in the GA group). No significant differences were seen between GA and AC groups in terms of extent of resection (MD: 3.77, p = 0.38, I2 = 91 %), rates of gross total resection (OR: 1.20, p = 0.69, I2 = 74 %), OR time (MD: 5.96, p = 0.15, I2 = 0 %), or length of stay (MD: −3.39, p = 0.21, I2 = 92 %).</div></div><div><h3>Conclusion</h3><div>AC is not inferior to surgery under GA for extent of resection of intra-axial brain tumors, with comparable rates of GTR and EOR. While non-significant, current data trends towards shorter operating time and length of stay as well for AC group patients.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"40 ","pages":"Article 102007"},"PeriodicalIF":0.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of ruptured intracranial dissecting aneurysm associated with neurosyphilis","authors":"Ziwei Xu ,&nbsp;Jie Chang ,&nbsp;Jun Shu ,&nbsp;Yiping Zhou ,&nbsp;Aijuan Yan ,&nbsp;Chunhui Gu ,&nbsp;Lutian Bai ,&nbsp;Wenshi Wei","doi":"10.1016/j.inat.2025.102004","DOIUrl":"10.1016/j.inat.2025.102004","url":null,"abstract":"<div><div>Intracranial dissecting aneurysm secondary to neurosyphilis is rare with only sporadic literature. Due to the insidious nature of the disease, as well as the rapid and dynamic changes of the intectious intracranial aneurysm, the outcome of treatment was not satisfactory in published reports. Here we report a case of intracranial dissecting aneurysm secondary to syphilis, who was successful embolized the aneurysm and treated with the neurosyphilis.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"39 ","pages":"Article 102004"},"PeriodicalIF":0.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficacy of prone position therapy in patients with acute brain Injury: A prospective observational study","authors":"Mei-Hua Wang ,&nbsp;Wei Chen ,&nbsp;Jie Song ,&nbsp;Hao-Yue Yuan ,&nbsp;Zhuo-Ying Du ,&nbsp;Qiang Yuan ,&nbsp;Jin Hu ,&nbsp;Gang Wu ,&nbsp;Lei Yang","doi":"10.1016/j.inat.2025.102005","DOIUrl":"10.1016/j.inat.2025.102005","url":null,"abstract":"<div><h3>Background</h3><div>Acute brain injury (ABI) frequently coexists with severe lung injury, leading to significant challenges. This study investigates the impact of prone position (PP) on the patients with ABI.</div></div><div><h3>Methods</h3><div>This prospective observational study was conducted at Huashan Hospital, enrolling patients with ABI requiring mechanical ventilation. ICP and ABP were continuously monitored. PP therapy was initiated based on clinical assessments. We evaluated ICP, CPP, oxygenation, and hemodynamics at three time points: baseline (T0), during therapy (T1), and after therapy (T2). LUS, CT, and ABG were performed. The primary outcomes included imaging results and clinical endpoints, while secondary outcomes focused on complications related to PP.</div></div><div><h3>Results</h3><div>Nine patients with ABI were enrolled, with a total of 13 episodes of PP analyzed. ICP notably elevated (14.8 ± 5.5 mmHg vs. 20.7 ± 6.0 mmHg, P &lt; 0.05). No significant changes in CPP were observed across T0, T1, and T2; however, oxygen saturation significantly improved during PP. LUS decreased significantly from T0 to T2 (8.60 ± 3.50 vs. 20.80 ± 3.71, P &lt; 0.001). Seven patients displayed improved pulmonary imaging. One patient recovered fully, 7 showed improvement, and 1 succumbed. Complications related to PP were recorded in 6 patients, including two cases of ocular complications and five pressure ulcers.</div></div><div><h3>Conclusion</h3><div>This study underscores the efficacy and safety of PP in patients with ABI complicated by severe lung injury. Continuous multimodal monitoring of neurological status during the intervention is crucial. Further research with larger sample is necessary to validate these findings and enhance patient outcomes.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"39 ","pages":"Article 102005"},"PeriodicalIF":0.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-drill craniostomy and perioperative treatment for chronic subdural hematoma: A single-center experience","authors":"Tao Wu,&nbsp;Xu Chen,&nbsp;Yueping Wang,&nbsp;Xianghua Zhang,&nbsp;Jing Zhang,&nbsp;Jianjun Sun,&nbsp;Cang Liu","doi":"10.1016/j.inat.2025.102001","DOIUrl":"10.1016/j.inat.2025.102001","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>The current research focuses on surgical safety and postoperative recurrence of chronic subdural hematoma (CSDH) treatment. This study proposes a micro-drill craniostomy drainage combined with perioperative treatment. The aim is to describe and validate this treatment approach and explore the risk factors influencing recurrence, to further improve the treatment outcomes for CSDH.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on patients who underwent surgery for CSDH from 2018 to 2023. These patients were divided into two groups based on recurrence, and multiple logistic regression analyses were performed to identify the independent factors of postoperative recurrence. Additionally, detailed descriptions of the micro-drill craniostomy drainage surgical technique and perioperative treatment plan were provided.</div></div><div><h3>Results</h3><div>A total of 106 patients with 140 CSDH were treated surgically. All patients experienced varying degrees of improvement in their clinical symptoms. No perioperative deaths or surgical complications occurred. Twelve recurrence cases were observed (8.6 %), 9 of which were managed through conservative treatment. The remaining three cases were treated with the same surgical procedure and urokinase injection, and no recurrence was observed during the last follow-up. After univariate analyses of all the clinical variables, the rate of recurrence was significantly lower in urokinase injection (P = 0.001) and long drainage duration (P = 0.042). Multiple logistic regression analysis identified the absence of postoperative urokinase injection was an independent risk factor for recurrence (odds ratio: 0.011, 95 % confidence interval: 0 – 0.485, P = 0.018), after adjustment for age, anticoagulant therapy, CT density, maximal thickness, pneumocrania, and other risk factors.</div></div><div><h3>Conclusion</h3><div>The combination of micro-drill craniostomy drainage and perioperative atorvastatin treatment is safe and effective for CSDH. It is recommended that urokinase injection as a routine treatment CSDH and further prospective randomized controlled trial is needed to validate its usage details and efficacy.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"39 ","pages":"Article 102001"},"PeriodicalIF":0.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadvertent Compromise of the thalamogeniculate artery during surgery for invasive tentorial notch Meningioma: A case report","authors":"Guive Sharifi ,&nbsp;Esmaeil Mohammadi ,&nbsp;Nader Akbari Dilmaghani ,&nbsp;Elham Paraandavaji ,&nbsp;Ali Jafari","doi":"10.1016/j.inat.2025.102009","DOIUrl":"10.1016/j.inat.2025.102009","url":null,"abstract":"<div><div>Meningiomas, usually benign brain tumors, occasionally exhibit aggressive behavior, as seen in tentorial notch meningiomas (TNMs). We detail a case of a 63-year-old woman with a TNM tightly adhered to vascular structures. Surgical resection led to inadvertent damage to the thalamogeniculate artery branch of posterior cerebral artery, leading to deep brain ischemia likely during clipping of basilar trunk. TNMs, comprising about 5% of meningiomas, present challenges due to their deep-seated location and intricate vasculature. Surgical planning must foresee potential vascular adhesions, and advanced angiography could aid in their identification. This case underscores the need for comprehensive understanding of cerebrovascular anatomy, emphasizing tailored surgical approaches and preparedness for managing vascular complications.</div></div>","PeriodicalId":38138,"journal":{"name":"Interdisciplinary Neurosurgery: Advanced Techniques and Case Management","volume":"39 ","pages":"Article 102009"},"PeriodicalIF":0.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143591527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}