Journal of Electrical Bioimpedance最新文献

{"title":"Storing Information Electrically in Human Skin.","authors":"Oliver Pabst,&nbsp;Øystein Magnus Sørebø,&nbsp;Karoline Sjøen Andersen,&nbsp;Erlend Lemva Ousdal,&nbsp;Sean William Bråthen,&nbsp;Badi Ur Rehman,&nbsp;Haiatullah Gholami,&nbsp;Zhijian Zhou,&nbsp;Koki Takahashi,&nbsp;Diriba Tasfaye Dumesso,&nbsp;Mellie Merete Livingston,&nbsp;Wesley Julian Lodewijk,&nbsp;Stian Sæther,&nbsp;Alireza Eskandari Turk,&nbsp;Peter Louis Uller","doi":"10.2478/joeb-2021-0010","DOIUrl":"https://doi.org/10.2478/joeb-2021-0010","url":null,"abstract":"<p><p>Human skin has been classified as a non-volatile memristor and it is shown that information can be stored within for at least three minutes. Here we investigate whether it is possible to store information up to 20 minutes. Furthermore, we investigate whether the information can be based on four different states, not just two (binary). We stored the information into the skin of the forehead of the test subjects under three different electrodes, which allows in principle for 64 different combinations (3 electrodes, 4 states) and one can think of numbers on the base of four. For this experiment, we decided on the numbers 123₄ and 302₄ (that correspond to numbers 27 and 50 in the decimal system). Writing of the different states was done by the application of DC voltage pulses that cause electro-osmosis in the sweat ducts (nonlinear electrical measurements). Based on our results, we were not able to distinguish between four different states. However, we can show that binary information storage in human skin is possible for up to 20 minutes.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39714420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Ischemic Injury in Human Intestine Ex Vivo with Electrical Impedance Spectroscopy.","authors":"Jie Hou,&nbsp;Runar Strand-Amundsen,&nbsp;Stina Hødnebø,&nbsp;Tor Inge Tønnessen,&nbsp;Jan Olav Høgetveit","doi":"10.2478/joeb-2021-0011","DOIUrl":"https://doi.org/10.2478/joeb-2021-0011","url":null,"abstract":"<p><p>Electrical impedance spectroscopy is a well-established tool for monitoring changes in the electrical properties of tissue. Most tissue and organ types have been investigated in various studies. As for the small intestine, there are several published studies conducted on pig and rat models. This study investigates the changes in passive electrical properties of the complete wall of the human intestine non-invasively during ischemia. We aim to use the passive electrical properties to assess intestinal viability. The bioimpedance measurements were performed using a two-electrode set-up with a Solartron 1260 Impedance/gain-phase analyser. The small intestinal samples were resected from patients who underwent pancreaticoduodenectomy. Impedance measurements were conducted following resection by placing the electrodes on the surface of the intestine. A voltage was applied across the intestinal sample and the measured electrical impedance was obtained in the ZPlot software. Impedance data were further fitted into a Cole model to obtain the Cole parameters. The <i>P_y</i> value was calculated from the extracted Cole parameters and used to assess the cell membrane integrity, thus evaluate the intestinal viability. Eight small intestinal segments from different patients were used in this study and impedance measurements were performed once an hour for a ten-hour period. One hour after resection, the impedance decreased, then increased the next two hours, before decreasing until the end of the experiment. For all the intestinal segments, the <i>P_y</i> values first increased and reached a plateau which lasted for 1 - 2 hours, before it decreased irreversibly. The time interval where <i>P_y</i> value reached the maximum is consistent with reported viable/non-viable limits from histological analysis.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"82-88"},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39771376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impedance-based Real-time Monitoring of Neural Stem Cell Differentiation.","authors":"F J Shah,&nbsp;C Caviglia,&nbsp;K Zór,&nbsp;M Carminati,&nbsp;G Ferrari,&nbsp;M Sampietro,&nbsp;A Martínez-Serrano,&nbsp;J K Emnéus,&nbsp;A R Heiskanen","doi":"10.2478/joeb-2021-0006","DOIUrl":"https://doi.org/10.2478/joeb-2021-0006","url":null,"abstract":"<p><p>We present here the first impedance-based characterization of the differentiation process of two human mesencephalic fetal neural stem lines. The two dopaminergic neural stem cell lines used in this study, Lund human mesencephalic (LUHMES) and human ventral mesencephalic (hVM1 Bcl-X_L), have been developed for the study of Parkinsonian pathogenesis and its treatment using cell replacement therapy. We show that if only relying on impedance magnitude analysis, which is by far the most usual approach in, e.g., cytotoxicity evaluation and drug screening applications, one may not be able to distinguish whether the neural stem cells in a population are proliferating or differentiating. However, the presented results highlight that equivalent circuit analysis can provide detailed information on cellular behavior, e.g. simultaneous changes in cell morphology, cell-cell contacts, and cell adhesion during formation of neural projections, which are the fundamental behavioral differences between proliferating and differentiating neural stem cells. Moreover, our work also demonstrates the sensitivity of impedance-based monitoring with capability to provide information on changes in cellular behavior in relation to proliferation and differentiation. For both of the studied cell lines, in already two days (one day after induction of differentiation) equivalent circuit analysis was able to show distinction between proliferation and differentiation conditions, which is significantly earlier than by microscopic imaging. This study demonstrates the potential of impedance-based monitoring as a technique of choice in the study of stem cell behavior, laying the foundation for screening assays to characterize stem cell lines and testing the efficacy epigenetic control.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"34-49"},"PeriodicalIF":0.0,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39860497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Electrical Impedance Tomography and Ultrasonography for Determination of Solid and Cystic Lesion Resembling Breast Tumor Embedded in Chicken Phantom.","authors":"L Choridah,&nbsp;D Kurniadi,&nbsp;K Ain,&nbsp;M F Ulum,&nbsp;U Mukhaiyar,&nbsp;A D Garnadi,&nbsp;N H Setyawan","doi":"10.2478/joeb-2021-0008","DOIUrl":"https://doi.org/10.2478/joeb-2021-0008","url":null,"abstract":"<p><p>Ultrasonography (US) and Electrical Impedance Tomography (EIT) can be used to detect breast cancer. Ultrasonography is based on non-ionizing radiations without adverse biological effects. A set of electrodes was placed around the torso and a small alternating current (AC) was injected via two of the electrodes into the object. This study aimed to acquire preliminary data to evaluate the EIT method for differentiation of artificial solid and cystic tumors in comparison to standard US. This study used a phantom made from chicken meat. In order to obtain the image of the solid tumor, an olive with carrot insertion was done, and the cystic tumor was created by filling a small balloon with water. GE Logic C5 ultrasound was performed with a 12 MHz linear transducer. For EIT measurement, 16 ECG electrodes and 32 ECG electrodes were placed. Data processing was done using the Graz consensus Reconstruction algorithm for EIT (GREIT) and Newton's One Step Error Reconstructor (NOSER) methods. The artificial solid tumor produced an ultrasound image of an oval, inhomogeneous lesions. The GREIT method with 16 electrodes of artificial solid tumor did not show a match between the reconstructed image and the original object containing 2 anomalies, but a match was found with 32 electrodes. In the NOSER method, both 16 and 32 electrodes showed a match. Ultrasound of the artificial cystic tumor showed an oval, circumscribed, anechoic with posterior enhancement. Both the GREIT and NOSER methods using the artificial cystic tumor showed a match between the reconstructed image and the original object containing two anomalies. EIT has a lower imaging resolution in comparison to ultrasonography, but is progressively maturing as a tool for monitoring and imaging. The solid and cystic anomalies on the phantoms were visualized by the GREIT and NOSER methods except for the solid anomaly with the GREIT 16 electrodes.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39860498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioimpedance to Assess the Body Composition of High-performance Karate Athletes: Applications, Advantages and Perspectives.","authors":"Luciana Rossi","doi":"10.2478/joeb-2021-0009","DOIUrl":"https://doi.org/10.2478/joeb-2021-0009","url":null,"abstract":"<p><p>Karate, a millennial martial art, was recently inserted among traditional Olympic combat sports for the Olympic Games in Japan. The aim of the present study is to determine, through bioimpedance analysis, the body composition of high-performance athletes participating in the São Paulo Olympic Karate Project. Participants were 22 athletes of both sexes, average age of 23.6 (6.0) years old, body mass of 66.6 (13.5) kg and fat percentage of 16.6 (5.5)%. Bioimpedance test indicated significant differences between sexes related to sexual dysmorphia, which had an impact on bioelectrical variables. Through comparative evaluation between male and female athletes, this study contributes to body composition analysis, indicating that, in the future, related bioimpedance tests should be used beyond their classical application, including phase angle, muscle function and other attributes.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"69-72"},"PeriodicalIF":0.0,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39714419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrical Impedance Tomography - Recent Applications and Developments.","authors":"Sofiene Mansouri,&nbsp;Yousef Alharbi,&nbsp;Fatma Haddad,&nbsp;Souhir Chabcoub,&nbsp;Anwar Alshrouf,&nbsp;Amr A Abd-Elghany","doi":"10.2478/joeb-2021-0007","DOIUrl":"https://doi.org/10.2478/joeb-2021-0007","url":null,"abstract":"<p><p>Electrical impedance tomography (EIT) is a low-cost noninvasive imaging method. The main purpose of this paper is to highlight the main aspects of the EIT method and to review the recent advances and developments. The advances in instrumentation and in the different image reconstruction methods and systems are demonstrated in this review. The main applications of the EIT are presented and a special attention made to the papers published during the last years (from 2015 until 2020). The advantages and limitations of EIT are also presented. In conclusion, EIT is a promising imaging approach with a strong potential that has a large margin of progression before reaching the maturity phase.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"50-62"},"PeriodicalIF":0.0,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39714418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrical Impedance Characterization of <i>in Vivo</i> Porcine Tissue Using Machine Learning.","authors":"Stephen Chiang,&nbsp;Matthew Eschbach,&nbsp;Robert Knapp,&nbsp;Brian Holden,&nbsp;Andrew Miesse,&nbsp;Steven Schwaitzberg,&nbsp;Albert Titus","doi":"10.2478/joeb-2021-0005","DOIUrl":"https://doi.org/10.2478/joeb-2021-0005","url":null,"abstract":"<p><p>The incorporation of sensors onto the stapling platform has been investigated to overcome the disconnect in our understanding of tissue handling by surgical staplers. The goal of this study was to explore the feasibility of <i>in vivo</i> porcine tissue differentiation using bioimpedance data and machine learning methods. <i>In vivo</i> electrical impedance measurements were obtained in 7 young domestic pigs, using a logarithmic sweep of 50 points over a frequency range of 100 Hz to 1 MHz. Tissues studied included lung, liver, small bowel, colon, and stomach, which was further segmented into fundus, body, and antrum. The data was then parsed through MATLAB's classification learner to identify the best algorithm for tissue type differentiation. The most effective classification scheme was found to be cubic support vector machines with 86.96% accuracy. When fundus, body and antrum were aggregated together as stomach, the accuracy improved to 88.03%. The combination of stomach, small bowel, and colon together as GI tract improved accuracy to 99.79% using fine k nearest neighbors. The results suggest that bioimpedance data can be effectively used to differentiate tissue types <i>in vivo</i>. This study is one of the first that combines <i>in vivo</i> bioimpedance tissue data across multiple tissue types with machine learning methods.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2021-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39327991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technology of Two-dimensional Bioimpedance Analysis of the Human Body Composition.","authors":"S P Shchelykalina,&nbsp;D V Nikolaev,&nbsp;V A Kolesnikov,&nbsp;K A Korostylev,&nbsp;O A Starunova","doi":"10.2478/joeb-2021-0004","DOIUrl":"https://doi.org/10.2478/joeb-2021-0004","url":null,"abstract":"<p><p>The BIA primary result sheets as a rule contain one-dimensional graphical scales with a selected area of normal values. In 1994, Piccoli <i>et al</i>. proposed BIVA, an alternative form of BIA data presentation, where two bioimpedance parameters are considered simultaneously as tolerance ellipses: resistance and reactance normalized to height. The purpose of this study is to develop an approach to data analysis in body composition bioimpedance research in two-dimensional representations. The data of 1.124.668 patients aged 5 to 85 years who underwent a bioimpedance study in Russian Health Centers from 2009 to 2015 were used. Statistical programming in the R Studio environment was carried out to estimate two-dimensional distribution densities of pairs of body composition parameters for each year of life. The non-Gaussian distribution is found in most parameters of bioimpedance analysis of body composition for most ages (Lilliefors test, p-value << 0.0001). The slices of the actual two-dimensional distribution pairs of body composition parameters had an irregular shape. The authors of the article propose using the actually observed distribution for populations where numerous bioimpedance studies have already been carried out. Such technology can be called two-dimensional bioimpedance analysis of human body composition (2DBIA). The 2DBIA approach is clearer for practitioners and their patients due to the use of body composition parameters in addition to electrical impedance parameters.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"17-25"},"PeriodicalIF":0.0,"publicationDate":"2021-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39328049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmental Volume and Circulatory Changes that Occur in Humans and Rhesus Monkeys During 4 Hour, -6 Degree Head Down Tilt.","authors":"Leslie David Montgomery, Clarence Oloff","doi":"10.2478/joeb-2021-0003","DOIUrl":"10.2478/joeb-2021-0003","url":null,"abstract":"<p><p>Nonhuman primates are often used to investigate physiologic processes that occur in man during aerospace/cardiovascular orthostatic research. Few studies have compared nonhuman primates and man under identical test conditions to assess the degree of similarity between the two species. Impedance plethysmography was used to measure calf, thigh, pelvic, thoracic, upper arm, and lower arm volume changes in eight rhesus (Macacca Mulatta) monkeys and twelve human subjects during four hour exposures to -6 degree head down tilt (HDT).</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"11-16"},"PeriodicalIF":0.0,"publicationDate":"2021-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39328048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrical Bioimpedance: From the Past to the Future.","authors":"Leigh C Ward","doi":"10.2478/joeb-2021-0001","DOIUrl":"https://doi.org/10.2478/joeb-2021-0001","url":null,"abstract":"<p><p>This year, 2021, marks the \"coming of age\" for JoEB with its indexing in PubMed Central. It is also a century since some of the earliest studies on tissue impedance. This editorial briefly reviews the time-line of research in the field to mark this occasion.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"12 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39328045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}