Journal of Electrical Bioimpedance最新文献

{"title":"Multichannel Cell Detection in Microcompartments by Means of True Parallel Measurements using the Solartron S-1260.","authors":"T A Nguyen,&nbsp;D Echtermeyer,&nbsp;A Barthel,&nbsp;G Urban,&nbsp;U Pliquett","doi":"10.2478/joeb-2020-0008","DOIUrl":"https://doi.org/10.2478/joeb-2020-0008","url":null,"abstract":"<p><p>Designing proper frontend electronics is critical in the development of highly sophisticated electrode systems. Multielectrode arrays for measuring electrical signals or impedance require multichannel readout systems. Even more challenging is the differential or ratiometric configuration with simultaneous assessment of measurement and reference channels. In this work, an eight-channel frontend was developed for contacting a 2×8 electrode array (8 measurement and 8 reference electrodes) with a large common electrode to the impedance gain-phase analyzer Solartron 1260 (S-1260). Using the three independent and truly parallel monitor channels of the S-1260, impedance of trapped cells and reference material was measured at the same time, thereby considerably increasing the performance of the device. The frontend electronics buffers the generator output and applies a potentiostatic signal to the common electrode of the chip. The applied voltage is monitored using the current monitor of the S-1260 via voltage/current conversion. The frontend monitors the current through the electrodes and converts it to a voltage fed into the voltage monitors of the S-1260. For assessment of the 8 electrode pairs featured by the chip, a relay-based multiplexer was implemented. Extensive characterization and calibration of the frontend were carried out in a frequency range between 100 Hz and 1 MHz. Investigating the influence of the multiplexer and the frontend electronics, direct measurement with and without frontend was compared. Although differences were evident, they have been negligible below one per cent. The significance of measurement using the complex S-1260-frontend-electrode was tested using Kohlrausch's law. The impedance of an electrolytic dilution series was measured and compared to the theoretical values. The coincidence of measured values and theoretical prediction serves as an indicator for electrode sensitivity to cell behavior. Monitoring of cell behavior on the microelectrode surface will be shown as an example.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/b6/joeb-11-049.PMC7531105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skeletal Muscle Mass by Bioelectrical Impedance Analysis and Calf Circumference for Sarcopenia Diagnosis.","authors":"C H González-Correa, M C Pineda-Zuluaga, F Marulanda-Mejía","doi":"10.2478/joeb-2020-0009","DOIUrl":"10.2478/joeb-2020-0009","url":null,"abstract":"<p><p>Skeletal muscle mass (SMM) plays an important role in health and physical performance. Its estimation is critical for the early detection of sarcopenia, a disease with high prevalence and high health costs. While multiple methods exist for estimating this body component, anthropometry and bioelectrical impedance analysis (BIA) are the most widely available in low- to middle-income countries. This study aimed to determine the correlation between muscle mass, estimated by anthropometry through measurement of calf circumference (CC) and skeletal mass index (SMI) by BIA. This was a cross-sectional and observational study that included 213 functional adults over 65 years of age living in the community. Measurements of height, weight, CC, and SMM estimated by BIA were made after the informed consent was signed. 124 women mean age 69.6 ± 3.1 years and 86 men mean age 69.5 ± 2.9 years had the complete data and were included in the analysis. A significant positive moderate correlation among CC and SMI measured by BIA was found (Pearson r= 0.57 and 0.60 for women and men respectively (p=0.0001)). A moderate significant correlation was found between the estimation of SMM by CC and by BIA. This suggests that CC could be used as a marker of sarcopenia for older adults in settings in lower-middle-income countries where no other methods of diagnosing muscle mass are available. Although the CC is not the unique parameter to the diagnosis of sarcopenia, it could be a useful procedure in the clinic to identify patients at risk of sarcopenia.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2020-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/2a/joeb-11-057.PMC7531101.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biosensor of Inflammation Biomarkers Based on Electrical Bioimpedance Analysis on Immobilized DNA Without Chemical Modification.","authors":"Modesto Gómez-López, Ángel Miliar-García, Nadia Mabel Pérez-Vielma, Eleazar Lara-Padilla, César Antonio González-Díaz","doi":"10.2478/joeb-2020-0006","DOIUrl":"10.2478/joeb-2020-0006","url":null,"abstract":"<p><p>The development of biosensors to identify molecular markers or specific genes is fundamental for the implementation of new techniques that allow the detection of specific Deoxyribonucleic acid (DNA) sequences in a fast, economic and simple way. Different detection techniques have been proposed in the development of biosensors. Electrical Bioimpedance Spectroscopy (EBiS) has been used for diagnosis and monitoring of human pathologies, and is recognized as a safe, fast, reusable, easy and inexpensive technique. This study proves the development of a complementary DNA (cDNA) biosensor based on measurements of EBiS and DNA's immobilization with no chemical modifications. The evaluation of its potential utility in the detection of the gene expression of three inflammation characteristic biomarkers (NLRP3, IL-1β and Caspase 1) is presented. The obtained results demonstrate that EBiS can be used to identify different gene expression patterns, measurements that were validated by Quantitative Polymerase Chain Reaction (qPCR). These results indicate the technical feasibility for a biosensor of specific genes through bioimpedance measurements on the immobilization of cDNA.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"31-37"},"PeriodicalIF":0.0,"publicationDate":"2020-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/cf/joeb-11-031.PMC7531096.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrode Positioning to Investigate the Changes of the Thoracic Bioimpedance Caused by Aortic Dissection - A Simulation Study.","authors":"V Badeli,&nbsp;G M Melito,&nbsp;A Reinbacher-Köstinger,&nbsp;O Bíró,&nbsp;K Ellermann","doi":"10.2478/joeb-2020-0007","DOIUrl":"https://doi.org/10.2478/joeb-2020-0007","url":null,"abstract":"Abstract Impedance cardiography (ICG) is a non-invasive method to evaluate several cardiodynamic parameters by measuring the cardiac-synchronous changes in the dynamic transthoracic electrical impedance. ICG allows us to identify and quantify conductivity changes inside the thorax by measuring the impedance on the thorax during a cardiac cycle. Pathologic changes in the aorta, like aortic dissection, will alter the aortic shape as well as the blood flow and consequently, the impedance cardiogram. This fact distorts the evaluated cardiodynamic parameters, but it could lead to the possibility to identify aortic pathology. A 3D numerical simulation model is used to compute the impedance changes on the thorax surface in case of the type B aortic dissection. A sensitivity analysis is applied using this simulation model to investigate the suitability of different electrode configurations considering several patient-specific cases. Results show that the remarkable pathological changes in the aorta caused by aortic dissection alters the impedance cardiogram significantly.","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"38-48"},"PeriodicalIF":0.0,"publicationDate":"2020-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/2a/joeb-11-038.PMC7531103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Physiological Swelling on Conductivity Distribution in Lower Leg Subcutaneous Tissue by Electrical Impedance Tomography.","authors":"R Ogawa,&nbsp;M R Baidillah,&nbsp;S Akita,&nbsp;M Takei","doi":"10.2478/joeb-2020-0004","DOIUrl":"https://doi.org/10.2478/joeb-2020-0004","url":null,"abstract":"<p><p>There is a strong need for a non-invasive measurement technique that is capable of accurately identifying the physiological condition change or heterogeneity of subcutaneous adipose tissue (SAT) by localizing the abnormalities within the compartment. This paper aims to investigate the feasibility of Electrical Impedance Tomography (EIT) to assess the interstitial fluid in subcutaneous adipose tissue as an enhancement method of bioelectrical impedance spectroscopy (BIS). Here, we demonstrate the preliminary result of EIT with a wearable 16 electrodes sensor. The image-based reference EIT with fat weighted threshold method is proposed. In order to evaluate the performance of our novel method, a physiological swelling experiment is conducted, and Multi-Frequency Bioelectrical Impedance Analysis (MFBIA) is also applied as a comparison with EIT results. The experimental results showed that the proposed method was able to distinguish the physiological swelling condition and effectively to remove the unexpected background noise. Furthermore, the conductivity variation in the subcutaneous layer had a good correlation with extracellular water volume change from MFBIA data; the correlation coefficient R² = 0.927. It is concluded that the proposed method provides a significant prospect for SAT assessment.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/49/joeb-11-019.PMC7531098.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Body Composition and Nutritional Risks in Young Ballet Dancers - The Bioelectrical Impedance Analysis.","authors":"Maria Alessandra Gammone, Nicolantonio D'Orazio","doi":"10.2478/joeb-2020-0005","DOIUrl":"10.2478/joeb-2020-0005","url":null,"abstract":"<p><strong>Background: </strong>Young ballet dancers are at risk of health issues associated with altered nutritional status and of relative energy deficiency in sport compared to the general population.</p><p><strong>Aim: </strong>To evaluate the nutritional status and body composition in ballet dancers.</p><p><strong>Materials and methods: </strong>The study group consisted of 40 young ballet dancers (mean age 19.97 years). Height and weight were measured and body mass index was calculated in all subjects (mean BMI value 19.79 kg/m², SD: 2.051). Body composition was estimated using the bioelectrical impedance method.</p><p><strong>Results: </strong>The dancers' fat-free mass was 47.33 kg (SD: 5.064) and, on the average, body fat represented the 15.92% (SD: 16.91) of their body weight.</p><p><strong>Conclusions: </strong>Ballet dancers, who usually show significantly lower BMI values compared to the general population, also displayed body fat values under the suggested range. Some screening for altered nutritional status should be performed. In addition, education programs should be recommended in young ballet dancers, in order to inform about energy and nutrition requirements for health and training and to prevent malnutrition-related problems.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/7d/joeb-11-026.PMC7531100.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducing the Hybrid \"K-means, RLS\" Learning for the RBF Network in Obstructive Apnea Disease Detection using Dual-tree Complex Wavelet Transform Based Features.","authors":"Javad Ostadieh, Mehdi Chehel Amirani","doi":"10.2478/joeb-2020-0002","DOIUrl":"10.2478/joeb-2020-0002","url":null,"abstract":"<p><p>Apnea is one of the deadliest diseases that can be prevented and cured if it is detected in time. In this paper, we propose a precise method for early detection of the obstructive sleep apnea (OSA) disease using the latest feature selection and extraction methods. The feature selection in this paper is based on the Dual tree complex wavelet (DT-CWT) coefficients of the ECG signals of several patients. The feature extraction from these coefficients is done using frequency and time techniques. The Feature selection is done using the spectral regression discriminant analysis (SRDA) algorithm and the classification is performed using the hybrid RBF network. A hybrid RBF neural network is introduced in this paper for detecting apnea that is much less computationally demanding than the previously presented SVM networks. Our findings showed a 3 percent improvement in the detection and at least a 30 percent reduction in the computational complexity in comparison with methods that have been presented recently.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"4-11"},"PeriodicalIF":0.0,"publicationDate":"2020-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/27/joeb-11-004.PMC7531097.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fast Electrical Characterization with Low Hardware Requirement.","authors":"Uwe Pliquett","doi":"10.2478/joeb-2020-0001","DOIUrl":"https://doi.org/10.2478/joeb-2020-0001","url":null,"abstract":"Electrical impedance spectroscopy can be performed using a great variety of methods and instrumentation. The most popular method, sweeping though a frequency range and measuring the impedance, either magnitude and phase or real and imaginary part at each desired frequency, offers high precision due to selective amplifiers and high dynamic range with respect to impedance magnitude. Highly sophisticated laboratory equipment guarantees robust measurement while software packages assist the interpretation of the measurement results. Although automated impedance analyzers are reasonably fast, the physical limitation of signal engagement at each measurement frequency always applies. Traditionally, the majority of the impedance analyzers are bulky and expensive and thus not suited for process instrumentation. During the last two decades, more and more economic instruments with small dimensions and low energy constraints conquer the market. Although the majority of these devices work in the frequency domain, time domain based approaches are increasingly offered.","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/85/joeb-11-001.PMC7531099.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmental Volume Changes that Occur in Nonhuman Primates During Short Term Head Up (HUT) and Head Down (HDT) Tilt.","authors":"Leslie David Montgomery,&nbsp;Clarence Oloff","doi":"10.2478/joeb-2020-0003","DOIUrl":"https://doi.org/10.2478/joeb-2020-0003","url":null,"abstract":"<p><p>Nonhuman primates are often used in biomedical research and to investigate physiologic processes that occur in man. Impedance plethysmography was used to measure calf, thigh, pelvic, abdominal, and thoracic volume changes in ten Rhesus and eight squirrel monkeys during five-minute exposures to HUT and HDT at angles of 5, 10, and 20 degrees. Calf, rump and tail measurements were made in three squirrel monkeys at 10 and 20 degrees of HUT and HDT. Fluid volume changes in all segments of the Rhesus monkeys were found to change during HUT an HDT in direct relation to the angle of tilt used. However, the volume changes that occurred in the squirrel monkeys were found to be quite different. Their calf, thigh, and pelvic segments lost volume during both HUT and HDT while their abdominal and thoracic segments responded similarly to those of the Rhesus monkeys. These results and those of the calf/tail measurements of the squirrel monkeys suggest that they may utilize their tails as a compensatory reservoir during postural changes and therefore, may not be an appropriate animal model for man under some orthostatic test conditions.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"11 1","pages":"12-18"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/fe/joeb-11-012.PMC7531102.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrowband Array Processing Beamforming Technique for Electrical Impedance Tomography.","authors":"Venkatratnam Chitturi, Nagi Farrukh","doi":"10.2478/joeb-2019-0014","DOIUrl":"10.2478/joeb-2019-0014","url":null,"abstract":"<p><p>Electrical impedance tomography (EIT) has a large potential as a two dimensional imaging technique and is gaining attention among researchers across various fields of engineering. Beamforming techniques stem from the array signal processing field and is used for spatial filtering of array data to evaluate the location of objects. In this work the circular electrodes are treated as an array of sensors and beamforming technique is used to localize the object(s) in an electrical field. The conductivity distributions within a test tank is obtained by an EIT system in terms of electrode voltages. These voltages are then interpolated using elliptic partial differential equations. Finally, a narrowband beamformer detects the peak in the output response signal to localize the test object(s). Test results show that the beamforming technique can be used as a secondary method that may provide complementary information about accurate position of the test object(s) using an eight electrode EIT system. This method could possibly open new avenues for spatial EIT data filtering techniques with an understanding that the inverse problem is more likely considered here as a source localization algorithm instead as an image reconstruction algorithm.</p>","PeriodicalId":38125,"journal":{"name":"Journal of Electrical Bioimpedance","volume":"10 1","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/1b/joeb-10-096.PMC7851972.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25367482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}