{"title":"Murine typhus outbreak: Emergence of a new public health concerns in India","authors":"Mahendra Singh , Ashok Kumar Balaraman , Rachana Mehta, Sanjit Sah","doi":"10.1016/j.nmni.2024.101514","DOIUrl":"10.1016/j.nmni.2024.101514","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101514"},"PeriodicalIF":2.9,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolated from children in Japan, 2023","authors":"Mitsuyo Kawaguchiya , Noriko Urushibara , Meiji Soe Aung , Nobuhide Ohashi , Sho Tsutida , Kayo Kurashita , Masahiko Ito , Nobumichi Kobayashi","doi":"10.1016/j.nmni.2024.101513","DOIUrl":"10.1016/j.nmni.2024.101513","url":null,"abstract":"<div><h3>Background</h3><div>The prevalence of serotypes and antimicrobial resistance of <em>Streptococcus pneumoniae</em> was characterized among children thirteen years after the licensure of the pneumococcal conjugate vaccine (PCV) in Japan.</div></div><div><h3>Methods</h3><div>A total of 353 pneumococcal isolates were collected from Japanese children between March and July 2023. All the isolates were serotyped using genetic methods and tested for susceptibility to 14 antimicrobial agents.</div></div><div><h3>Results</h3><div>Among the 353 isolates, the prevalence rates of non-PCV13 and non-PCV20 serotypes were 96.9 % and 77.9 %, respectively, including the dominant non-PCV13/PCV20 serotypes 23A (16.1 %), 35B (15.3 %), 15A (10.5 %), 15C (9.3 %), and 34 (9.1 %), which accounted for 60.3 % of all isolates. The high non-susceptibility rates were observed for macrolides (erythromycin, azithromycin, and clarithromycin; ≥81.9 %) and tetracycline (80.7 %). Penicillin non-susceptibility and multidrug resistance (MDR) were detected in 49.9 % (6.8 % resistant and 43.1 % intermediate) and 68.3 % of the isolates, respectively. The three most common non-PCV13/PCV20 serotypes 15A, 23A, and 35B exhibited high prevalence rates of penicillin non-susceptibility (≥89.5 %) and MDR (≥81.5 %). Extensive drug resistance was observed in 10.5 % of all isolates belonging to six different serotypes (12F, 23A, 11A, 15A, 35B, and 15B) and in the non-encapsulated strains of <em>S. pneumoniae.</em></div></div><div><h3>Conclusions</h3><div>Our study revealed a higher prevalence of non-susceptibility to penicillin with MDR in the three most common non-PCV13/PCV20 serotypes 15A, 23A, and 35B, in Japan, suggesting their persistence in the PCV13 era.</div></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101513"},"PeriodicalIF":2.9,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Luis Bonilla-Aldana, Norma Constanza Ganem-Galindo, Gloria Elena Estrada-Cely, Martha Leonor Losada-Cordoba, Santiago Sarmiento-Gantiva, Marina Muñoz, Angie L. Ramírez, Luz H. Patiño, Juan David Ramírez, Alberto E. Paniz-Mondolfi, Alfonso J. Rodriguez-Morales, D. Katterine Bonilla-Aldana
{"title":"Ocular thelaziosis (Thelazia lacrymalis) in a harpy eagle (Harpia harpyja) from Colombia","authors":"Jorge Luis Bonilla-Aldana, Norma Constanza Ganem-Galindo, Gloria Elena Estrada-Cely, Martha Leonor Losada-Cordoba, Santiago Sarmiento-Gantiva, Marina Muñoz, Angie L. Ramírez, Luz H. Patiño, Juan David Ramírez, Alberto E. Paniz-Mondolfi, Alfonso J. Rodriguez-Morales, D. Katterine Bonilla-Aldana","doi":"10.1016/j.nmni.2024.101512","DOIUrl":"10.1016/j.nmni.2024.101512","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101512"},"PeriodicalIF":2.9,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nepal's Japanese encephalitis outbreak and the urgent need for updated vaccination guidelines","authors":"Amogh Verma, Sanjit Sah, Rachana Mehta, Ganesh Bushi, Ashok Kumar Balaraman, Sakshi Pandey, Manvinder Brar, Benjamin Wafula Simiyu","doi":"10.1016/j.nmni.2024.101509","DOIUrl":"10.1016/j.nmni.2024.101509","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101509"},"PeriodicalIF":2.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142437802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peyman Khademi , Amir Tukmechi , Abdulghaffar Ownagh
{"title":"Molecular detection and phylogeny analysis of Coxiella burnetii detected from cattle and buffalo milk based on plasmid cbhE gene in West Azerbaijan of Iran","authors":"Peyman Khademi , Amir Tukmechi , Abdulghaffar Ownagh","doi":"10.1016/j.nmni.2024.101495","DOIUrl":"10.1016/j.nmni.2024.101495","url":null,"abstract":"<div><div>Humans and animals may get Q fever, which is caused by the Gram-negative coccobacillus <em>Coxiella burnetii</em>. The symptoms of Q fever may include a self-limiting febrile illness, pneumonia, endocarditis, or hepatitis. Infections are classified as either acute or persistent. Cattle, sheep, and goats are the most prevalent reservoir animals for this zoonosis. This research was conducted to identify <em>C. burnetii</em> using transposable and isocitrate dehydrogenase genes (<em>IS1111</em>, <em>icd</em>) and <em>QpH1</em> plasmids. A total of 142 samples of raw buffalo and cow milk were collected from various locations within the West Azerbaijan region (see map). We used \"nested\" PCR techniques using primers based on the <em>IS1111</em> and <em>icd</em> genes of <em>C. burnetii</em>, as well as conserved and variable portions of plasmid sequences, to identify <em>C. burnetii</em> and their plasmids in milk samples from buffalo and calves. Out of 142 milk samples that were positive for the chromosomal transposable genes (<em>IS1111</em> and <em>icd</em>) at a rate of 16.9 percent (95 percent CI: 14.5 percent to 19.6 percent) and 7.1 % (95 percent CI: 5.59 percent to 9.08 percent), respectively, 86 samples were positive for the <em>QpH1</em> plasmid at a rate of 60.5 percent (95 percent CI: 52.35 percent to 68.2 percent). Based on a phylogenetic study of the <em>icd</em> and <em>QpH1</em> genes, the majority of the isolates had a similarity of 99.45–99.9 percent. Conclusion: It was determined that the buffalo population in West Azerbaijan province represents a significant epidemiological factor with respect to Q fever and consequently public health.</div></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101495"},"PeriodicalIF":2.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amidu Alhassan , Lydia Sope Ajala , Bella Ode , Muhammad Alanjiro , Sumaira Rehman , Jones Onesime , Elie Kihanduka , Christian Tague , Kanza Farhan , Styves Banga , Excellent Rugendabanga , Alvin Manga , Gift Joseph Mbwambo , Samson Hangi , Francois Rhugendabanga , Innocent Mufungizi , Muhammad Furqan , Maher Ali Rusho , Mayar Moustafa Budair , Aymar Akilimali , Leonard Sironge
{"title":"Call for elimination program of Malaria among children under 5 years old living in refugee camps in eastern Democratic Republic of Congo","authors":"Amidu Alhassan , Lydia Sope Ajala , Bella Ode , Muhammad Alanjiro , Sumaira Rehman , Jones Onesime , Elie Kihanduka , Christian Tague , Kanza Farhan , Styves Banga , Excellent Rugendabanga , Alvin Manga , Gift Joseph Mbwambo , Samson Hangi , Francois Rhugendabanga , Innocent Mufungizi , Muhammad Furqan , Maher Ali Rusho , Mayar Moustafa Budair , Aymar Akilimali , Leonard Sironge","doi":"10.1016/j.nmni.2024.101508","DOIUrl":"10.1016/j.nmni.2024.101508","url":null,"abstract":"<div><div>Malaria is a significant public health challenge in the Democratic Republic of the Congo (DR Congo), with a high prevalence and mortality rate, particularly among children under five years old. This study examines the impact of malaria in eastern DR Congo, where armed conflict and humanitarian crises have resulted in overcrowded refugee and internally displaced persons (IDP) camps, exacerbating malaria transmission. Malnutrition, limited access to healthcare, and poor living conditions makes children under the age of five particularly vulnerable. Despite attempts by organizations such as the World Health Organization and various non-governmental organizations to supply insecticide-treated bed nets and antimalarial drugs, implementation in refugee camps is impeded by war, resource constraints, and insufficient healthcare facilities. A focused elimination approach that includes integrated vector control, enhanced diagnostic access, healthcare professional training, and community engagement is critical. Surveillance and research are critical for determining malaria prevalence and resistance patterns. Effective malaria treatment in refugee camps necessitates broad strategies to protect vulnerable children and lower disease burdens.</div></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101508"},"PeriodicalIF":2.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New human H5N1 case: Should we worry? A genetic perspective","authors":"Francesco Branda, Massimo Ciccozzi, Fabio Scarpa","doi":"10.1016/j.nmni.2024.101510","DOIUrl":"10.1016/j.nmni.2024.101510","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101510"},"PeriodicalIF":2.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chandipura virus: A looming threat to children in India","authors":"Priyanka Mohapatra, Ashok Kumar Balaraman, Rachana Mehta, Pramod Rawat, Sanjit Sah, Prakasini Satapathy","doi":"10.1016/j.nmni.2024.101503","DOIUrl":"10.1016/j.nmni.2024.101503","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101503"},"PeriodicalIF":2.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qiushi Zheng , Jian Bing , Shiling Han , Shuyun Guan , Tianren Hu , Lei Cai , Haiqing Chu , Guanghua Huang
{"title":"Biological and genomic analyses of Clavispora sputum sp. nov., a novel potential fungal pathogen closely related to Clavispora lusitaniae (syn. Candida lusitaniae) and Candida auris","authors":"Qiushi Zheng , Jian Bing , Shiling Han , Shuyun Guan , Tianren Hu , Lei Cai , Haiqing Chu , Guanghua Huang","doi":"10.1016/j.nmni.2024.101506","DOIUrl":"10.1016/j.nmni.2024.101506","url":null,"abstract":"<div><div>Several human fungal pathogens, including drug-resistant <em>Candida auris</em> and species of the <em>Candida haemulonii</em> complex, have emerged over the past two decades, posing new threats to human health. In this study, we report the isolation and identification of a novel species belonging to the genus <em>Clavispora</em>, herein named as <em>Cl</em><em>avispora</em> <em>sputum</em>, from a clinical sputum sample of a COVID-19 patient. <em>Cl</em><em>. sputum</em> is phylogenetically closely related to fungal pathogens <em>Clavispora lusitaniae</em> (syn. <em>Candida lusitaniae</em>) and <em>C. auris</em>. When grown on CHROMagar <em>Candida</em> Plus medium, <em>Cl. sputum</em> exhibited a similar coloration to <em>C. auris</em> strain CBS12372. <em>Cl. sputum</em> was able to develop weak filaments on CM medium. Although <em>Cl. sputum</em> and <em>Cl. lusitaniae</em> are phylogenetically closely related, comparative genomic and synteny analyses indicated significant chromosomal rearrangements between the two species. Although <em>Cl. sputum</em> could not grow at 37 °C under regular culture condition, an increased fungal burden in the lung tissue of a mouse systemic infection model implies that it could be a potential opportunistic pathogenic yeast in humans.</div></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101506"},"PeriodicalIF":2.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Re-emergence of Chandipura virus in India: Urgent need for public health vigilance and proactive management","authors":"Ashutosh Pareek, Runjhun Singhal, Aaushi Pareek, Anil Chuturgoon, Ranjit Sah, Rachana Mehta, Jaffar A. Al-Tawfiq, Vasso Apostolopoulos","doi":"10.1016/j.nmni.2024.101507","DOIUrl":"10.1016/j.nmni.2024.101507","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"62 ","pages":"Article 101507"},"PeriodicalIF":2.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}