New Microbes and New Infections最新文献

{"title":"Oropouche virus presenting in Italy after travel to Cuba","authors":"Francesco Branda, Massimo Ciccozzi, Fabio Scarpa","doi":"10.1016/j.nmni.2024.101450","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101450","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101450"},"PeriodicalIF":2.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002348/pdfft?md5=b4192d3b6e8e3d91f0ed561214b4b00d&pid=1-s2.0-S2052297524002348-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141594814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence of STSS in Japan: An assessment of the threat and containment strategies","authors":"Om Prakash Choudhary, Rashmi Rana, Priyanka, A. Babar Ali, Vyoma Sharma","doi":"10.1016/j.nmni.2024.101449","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101449","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101449"},"PeriodicalIF":2.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002336/pdfft?md5=1be7ae4cf28cdd464905368deed90269&pid=1-s2.0-S2052297524002336-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the cryptosporidiosis outbreak in Devon, England: Urgent measures for public health and water safety","authors":"Patrick Ashinze, Abdullaah Idris Agbabiaka, Okeoyo Tesleem Ademola, Onosegbe Moses Aikhuomogbe, Olajuwon Tolulope Joseph, Bonu Innocent Shu, Suleiman Nasiru Akobe, Onyinyechukwu Ndubuisi Joyce, Izuchukwu Jonathan Obidiegwu, Ekene Nnagha, Ngozi Peace Okoro","doi":"10.1016/j.nmni.2024.101448","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101448","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101448"},"PeriodicalIF":2.9,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002324/pdfft?md5=e3aa823163b6a0bb92fb2bc8cefbedc9&pid=1-s2.0-S2052297524002324-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First sighting of human H5N1 in Australia: A detailed account and public health implications","authors":"Amogh Verma, Divij Sharma, Manu Pant, Mahalaqua Nazli Khatib, Mahendra Pratap Singh, Quazi Syed Zahiruddin, Sarvesh Rustagi, Shilpa Gaidhane, Abhay M. Gaidhane","doi":"10.1016/j.nmni.2024.101447","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101447","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101447"},"PeriodicalIF":2.9,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002312/pdfft?md5=383c676077f369d459cfc9c31336c3d5&pid=1-s2.0-S2052297524002312-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing reports of streptococcal toxic shock syndrome from Japan","authors":"Aminath Shiba Ahmed, Kannan Subbaram, Razana Faiz, Zeba Un Naher, Punya Laxmi Manandhar, Sheeza Ali","doi":"10.1016/j.nmni.2024.101446","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101446","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101446"},"PeriodicalIF":2.9,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002300/pdfft?md5=8d7aa5dcf501be6349d0ccf5de361478&pid=1-s2.0-S2052297524002300-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of MMV Pandemic Response Box compounds to identify potent compounds against clinically relevant bacterial and fungal clinical isolates in vitro","authors":"Seshan Sivasankar ,&nbsp;Appalaraju Boppe ,&nbsp;Martin Peter Grobusch ,&nbsp;Sankarganesh Jeyaraj","doi":"10.1016/j.nmni.2024.101444","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101444","url":null,"abstract":"<div><h3>Background</h3><p>Multidrug resistant bacterial and fungal pathogens are resistant to a number of significant front-line drugs, hence, identification of new inhibitory agents to combat them is crucial. In this study, we aim to evaluate the activity of Pandemic Box compounds from Malaria Medicines Venture (MMV) against <em>A. baumannii</em> and <em>P. aeruginosa</em> bacterial, <em>C. auris, C. albicans and A. niger</em> fungal clinical isolates.</p></div><div><h3>Methods</h3><p>Isolates were initially screened with 201 antibacterial and 46 antifungal compounds (10 μM) using a microbroth dilution in triplicates to determine MIC. A persister assay was performed for bacterial pathogens.</p></div><div><h3>Results</h3><p>Out of 201 antibacterial compounds, twenty-nine and seven compounds inhibited the growth of <em>A. baumannii</em> and <em>P. aeruginosa</em> at 10 μM, respectively. MMV1580854, MMV1579788, eravacycline and epetraborole inhibited both the bacterial test isolates. In a persister assay, MMV1634390 showed complete bactericidal effect against <em>A. baumannii</em>. With antifungal activity compounds, <em>C. auris</em> responded to15 compounds, Six compounds inhibited <em>C. albicans</em> and one was effective against <em>A. niger</em> at 10 μM. The ratio of Minimum Fungicidal Concentration (MFC): Minimum Inhibitory Concentration (MIC) of MMV1782110 was 2 against <em>C</em>. <em>auris</em>. Eberconazole, amorolfine and luliconazole are fungicidal targeting <em>C. albicans</em> at a MFC: MIC ratio of 2.</p></div><div><h3>Conclusion</h3><p>Five compounds from MMV Pandemic Box were found to be inhibiting colistin and ceftazidime resistant <em>A. baumannii</em> clinical isolate, also against colistin and β-lactam resistant <em>P. aeruginosa</em> clinical isolate<em>.</em> MMV1634390 showed complete bactericidal effect against <em>A. baumannii</em> in a persister assay. MMV1782110, Eberconazole, amorolfine and luliconazole exhibited potent anti-fungal activity. Further investigations are warranted to identify the targets and mechanism.</p></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101444"},"PeriodicalIF":2.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002282/pdfft?md5=5df45a15151a889dbffcb2e2a08d7cfc&pid=1-s2.0-S2052297524002282-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First study of the detection of Human Herpes Virus-8 and major blood-borne viruses in iranian patients with SLE: A cross-sectional study","authors":"Leila Soltani ,&nbsp;Ava Hashempour ,&nbsp;Javad Moayedi ,&nbsp;Maryam Feili ,&nbsp;Zahra Musavi ,&nbsp;Mohammad Ali Nazarinia","doi":"10.1016/j.nmni.2024.101445","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101445","url":null,"abstract":"<div><h3>Background</h3><p>Systemic lupus erythematosus (SLE) is an autoimmune disease caused by genetic and environmental factors such as viral infections. Genomic and serologic tests were applied to detect significant blood-borne viruses in SLE patients to determine whether there was a possible association between viral infections and SLE.</p></div><div><h3>Methods</h3><p>Antibodies (Abs) against HHV-8, HCMV, EBV, HIV, HBV, and HCV in SLE patients suffering from SLE were assessed by ELISA. In addition, HHV-8 DNA and HIV-1 RNA were quantified by real-time PCR, and the HCV and HBV genomes were detected using nested PCR.</p></div><div><h3>Results</h3><p>Compared to those in the control group, a high prevalence of anti-HHV-8 (p &lt; 0.0001), anti-HCMV (p = 0.014), and anti-EBV (p = 0.017) Abs was detected in SLE patients. HHV-8, HIV, HCV, and HBV genomic tests were negative in both groups, while only 1.1 %, 2.2 %, and 1.1 % of SLE patients were positive for anti-HIV, anti-HCV Abs, and HBsAg, respectively. The most frequent major complaint in patients was arthralgia (76.7 %).</p></div><div><h3>Conclusions</h3><p>The increased prevalence of anti-HHV-8 Abs may not be related to the natural history of infection but to molecular mimicry. Increased anti-HCMV and anti-EBV Abs may also be associated with the development of SLE and may play direct or indirect roles in such infections or molecular mimicry. Since arthralgia is the most common symptom in SLE patients, the presence of these symptoms in any patient is a suggestive clue for the diagnosis of SLE. Defining the typical pattern of SLE in divergent nations with distinct environmental and geographical factors can be beneficial for obtaining a prompt diagnosis.</p></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101445"},"PeriodicalIF":2.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002294/pdfft?md5=0709b9a59bdbc373d5c505d00128e4c2&pid=1-s2.0-S2052297524002294-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence for transmission of SARS-CoV-2 at religious mass gatherings: A systematic review","authors":"Ndiaw Goumballa ,&nbsp;Van Thuan Hoang ,&nbsp;Jaffar A. Al-Tawfiq ,&nbsp;Cheikh Sokhna ,&nbsp;Philippe Gautret","doi":"10.1016/j.nmni.2024.101442","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101442","url":null,"abstract":"<div><h3>Background</h3><p>Transmission of SARS-CoV-2 at major mass gatherings (MGs) has been observed during the COVID-19 pandemic.</p></div><div><h3>Methods</h3><p>In this systematic review done according to the PRISMA guidelines, PubMed and Scopus databases were searched for relevant studies to describe the epidemiology of SARS-CoV-2 in relation to major religious MGs including the Grand Magal of Touba (GMT), Hajj, Umrah, Kumbh Mela, Arbaeen and Lourdes pilgrimage during the COVID-19 pandemic.</p></div><div><h3>Results</h3><p>Ten articles met the inclusion criteria and were included.</p><p>No cases of SARS-CoV-2 were detected at 2020 and 2021 GMT or at the 2020 Hajj. In a small study, 7 % of tested individuals were positive after the 2022 GMT. SARS-CoV-2 prevalence during the 2021–2022 Hajj and Umrah seasons varied from 0 to 15 % in different studies. At the 2021 Kumbh Mela, 0.4 million COVID-19 cases were diagnosed among returning pilgrims across India and 1 % tested positive during a one-day survey conducted on participants. During the 2021 Arbaeen pilgrimage, 3 % pilgrims were tested positive. No relevant data were found in relation to SARS-CoV-2 transmission at the 2021 Arbaeen and Lourdes pilgrimages.</p></div><div><h3>Conclusion</h3><p>The transmission of the SARS-CoV-2 virus during religious MG events depends on many factors such as: the number and density of pilgrims, the intensity of circulation of the virus in the hosting country and in countries sending international participants at the time of the event, the transmissibility of virus variants at the time of the event, the various preventive measures adopted, and the immune status of the pilgrims.</p></div>","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101442"},"PeriodicalIF":4.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002269/pdfft?md5=abfd8bbe45e8aaf02b98e5075c314fd7&pid=1-s2.0-S2052297524002269-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141322753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"R21/Matrix-M™ malaria vaccine: A realm of hope for combating malaria in developing countries?","authors":"Kanza Farhan,&nbsp;Burhan Tariq,&nbsp;Fiza Sohail,&nbsp;Navera Saeed,&nbsp;Aymar Akilimali","doi":"10.1016/j.nmni.2024.101443","DOIUrl":"https://doi.org/10.1016/j.nmni.2024.101443","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101443"},"PeriodicalIF":2.9,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002270/pdfft?md5=41d2d5dcf042650fa568c8ea1f7f9e37&pid=1-s2.0-S2052297524002270-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal-resistant ringworm in KwaZulu-Natal: A new challenge in infectious disease management","authors":"Prakasini Satapathy,&nbsp;Shilpa Gaidhane,&nbsp;Abhay M. Gaidhane,&nbsp;Quazi Syed Zahiruddin,&nbsp;Sarvesh Rustagi,&nbsp;Mubarick Nungbaso Asumah","doi":"10.1016/j.nmni.2024.101440","DOIUrl":"10.1016/j.nmni.2024.101440","url":null,"abstract":"","PeriodicalId":38074,"journal":{"name":"New Microbes and New Infections","volume":"60 ","pages":"Article 101440"},"PeriodicalIF":2.9,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2052297524002245/pdfft?md5=147eba0d293b10d59bc5080e58172200&pid=1-s2.0-S2052297524002245-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}