Egyptian Journal of Ear, Nose, Throat and Allied Sciences最新文献

{"title":"Assessment of the Binaural Interaction Component of the Auditory Brain Stem Response in Children with Stuttering","authors":"Mirhan Eldeeb, N. Hamouda, Elfatih E Bushara, S. Assal","doi":"10.21608/ejentas.2022.140724.1517","DOIUrl":"https://doi.org/10.21608/ejentas.2022.140724.1517","url":null,"abstract":"Introduction: This study aims to compare the binaural interaction component of auditory brainstem response (ABR-BIC) between children with stuttering and normal peers, and to correlate ABR-BIC parameters with stuttering severity instrument -3. Patients and Methods: Twenty Stuttering children, diagnosed according to the criteria of stuttering severity instrument -3, and 20 normal age and gender matched peers were included. Click evoked ABRs were recorded through right monaural, left monaural and binaural stimulation at 80 dBnHL in both study groups. ABR-BIC was calculated as the difference between the binaurally evoked ABR response and the algebraic sum of the left and right monaural responses, and ABR-BIC parameters were measured. Results: ABR-BIC latency and duration were significantly prolonged in the stuttering group compared to the control group, while ABR-BIC amplitude and area under the curve (AUC) were comparable. Also, ABR-BIC amplitude and AUC were significantly correlated with stuttering severity. Conclusion: The results of this study point to impaired timing and reduced overall magnitude of binaural interaction at the brainstem level in stuttering children. 2090-0740,","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"151 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77764267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Language Skills and Degree of Hearing in a Group of Preschool Egyptian Children with Hearing Loss","authors":"E. Ezzat, D. Osman, Essam A. Behairy, Asmaa Tieama, H. anwar","doi":"10.21608/ejentas.2022.142495.1524","DOIUrl":"https://doi.org/10.21608/ejentas.2022.142495.1524","url":null,"abstract":"Background: Language acquisition in hearing-impaired children is enhanced by adequate exposure to auditory stimuli achieved by early, regular hearing aid fitting and proper rehabilitation programs for optimum linguistic experience. Objective: This research aims to examine the relationship between hearing impairment (HI) (at degrees of moderate to severe) and various language skills development to understand these issues better and plan appropriate intervention programs. Patients and Methods: 25 cases (aged from 3 to less than 5) with moderate to severe degree of sensory neural hearing loss (SNHL) and average non-verbal intelligence participated in our study, recruited from Phoniatric unit outpatient clinic in Menofia University Hospital, from September 2020 to June 2021. The selected patients were subjected to language assessment protocol with the “A Proficient Preschooler Language Evaluation Tool” (APPLE). The results of the cases were compared to 25 control subjects matched for age and gender. Results: By studying the correlation between cases and control subjects (regarding the development of different language skills using APPLE tool which presented in (receptive, expressive, total language, action picture subtests, narrative skills subtests, comprehension skills test, understanding simple question, and articulation test), there was a highly significant difference. Highly significant correlations were found between hearing aid use duration and language development and between the duration of rehabilitation and language development. Conclusion: Language acquisition of hearing-impaired children depends on the HI degree, early and regular wearing of hearing aid with the suitable family enviroment, and proper intervention programs.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"111 3S 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89373095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monoclonal anti-IgA antibody expression in the posterior commissure mucosae of laryngeal cancer patients","authors":"M. Rifai, Mohamed G. Negm, S. Abdalgaleel, A. Younes","doi":"10.21608/ejentas.2021.104404.1437","DOIUrl":"https://doi.org/10.21608/ejentas.2021.104404.1437","url":null,"abstract":"Department of 1,4Otolaryngology, 2Pathology, Kasr El Aini Hospital, Cairo Medical School, 3Biostatistics and Epidemiology Department, National Cancer Institute, Cairo University, Egypt. ABSTRACT Objective: It has been reported that the interarytenoid fold of the larynx (IAFL) is rarely affected by malignancy 1. It is therefore crucial that research be undertaken to delineate its structural differences of the posterior commissure of the larynx from other laryngeal sub-sites. Study Design: Comparing the expression of anti-IgA antibody in laryngeal tumor cells and the mucosa of the PC (free of tumor). The study aims to detect a specific immune response mounted by the host that might explain the previous observation. Setting: Twenty-seven specimens from patients suffering from T3 and T4 squamous cell carcinoma were included in the present study. Patients and Methods: Sample biopsies were procured from the tumor, the PC, and the tumor-free mucosae of the larynx, and were subjected to immunohistochemical study using a commercially prepared rabbit-hosted monoclonal antiIgA antibody. Several criteria were applied to evaluate the expression of IgA in all of the samples. Results: The posterior commissure was free of tumor involvement in all twenty-seven of the excised larynges. IgA expression was significantly higher in the PC epithelium than in the neighboring laryngeal epithelium devoid of tumor. One interesting result is the highly significant expression of IgA in the immunocytes located in the PC as compared to those in the tumor, where it is almost negligible. Conclusion: Immunohistochemical study further revealed a significant characteristic of the PC regarding its higher expression of IgA. Research should be directed toward revealing the factors that provide immunity and resistance in the PC area.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78364359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septal Necrosis as Primary Presentation for Mucormycosis in Covid-19 Era","authors":"A. Sweed, Mohamed Mobashir, E. Elsheikh, M. Elmaghawry","doi":"10.21608/ejentas.2022.132793.1502","DOIUrl":"https://doi.org/10.21608/ejentas.2022.132793.1502","url":null,"abstract":"Objectives: To report unusual presentation of sinonasal mucormycosis, To emphasize on importance of MRI sequences in dealing with mucormycosis cases. Patients and Methods: We reported a case with persistent rhinological symptoms after Covid-19 recovery, presented endoscopically with necrotic eschar/crust on nasal septum with apparently normal lateral nasal mucosa. MRI T2 fat suppression revealed inflammatory process within RT pterygopalatine / infratemporal fossa territory. Endoscopic sinus surgery was done for debridement of necrotic septal nasal mucosa, exploration of RT PPF / ITF shows pus emerging from it with necrosis of posterior feeding vessel of the nose \"SPA\". Nasal septum is characterized by double vascularity from both side, but sudden interruption from one side could not be compensated from healthy side leading to necrosis. Conclusion: Any persistent rhinological symptoms after covid-19 infection with necrotic eschar anywhere within rhino-orbital territory should be considered as mucormycosis till prove otherwise. © 2022, Egyptian Society of Ear Nose Throat and Allied Sciences. All rights reserved.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77645712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does FESS alter the sinonasal microbiome","authors":"H. Babu, Rohit Sharma, V. Sharma, R. Goyal, A. Rana","doi":"10.21608/ejentas.2022.69458.1340","DOIUrl":"https://doi.org/10.21608/ejentas.2022.69458.1340","url":null,"abstract":"Introduction: Chronic rhinosinusitis is a common health problem.However few studies comparing pre and post-FESS microorganisms and efficacy of FESS are present.The present study aims to analyze the alteration in sinonasal microbiome in patients of chronic rhinosinusitis with and without nasal polyposis after functional endoscopic sinus surgery. Patients and Methods: The prospective observational study was conducted in the Department of Otorhinolaryngology and Head Neck Surgery, SRMS IMS from November 2017 to April 2019 after the approval by the Research/Ethics Committee. All patients clinically diagnosed as Chronic Rhinosinusitis (CRS) with and without Nasal Polyposis posted for Functional Endoscopic Sinus Surgery (FESS) formed the study group.Culture analysis of specimen from middle meatus region was done twice first, prior to FESS and second 6 weeks post-FESS.The changes in the microbiome were then analysed. Results: In 31.4% patients methicillin resistant staphylococcus aureus was cultured prior to FESS. Other organisms cultured were Staphylococcus aureus, Pseudomonas, Aspergillus, E.coli, Rhizopus and E.Faecalis. Post-FESS cultures were obtained at 6 weeks. Staphylococcus aureus was cultured in 77% cases. No fungal microbes or MRSA were cultured post operatively. In 11.4 % cultures no microorganisms were detected. No statistical correlation was observed between the diagnosis and organisms cultured. Conclusion: The preoperative culture of MRSA and its absence in post-FESS cultures points to role in the pathogenesis of CRS. Fungal organisms Aspergillus and Rhizopus were cultured pre-operatively which were present in combination with bacteria supporting the co-infection theory. Effective role of FESS as surgical management is also consolidated.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81210556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Cholesteatoma using Diffusion Magnetic Resonance Imaging","authors":"Mohamed Abd ELNaeem, S. Gad, Ahmed Abd Elwhab, Amer Ahmed","doi":"10.21608/ejentas.2022.132526.1501","DOIUrl":"https://doi.org/10.21608/ejentas.2022.132526.1501","url":null,"abstract":"Introduction: Cholesteatoma is a retraction pocket or cyst lined by squamous epithelium containing keratin debris occurring in the pneumatized portions of temporal bone, have a propensity for growth, bone destruction and is considered “unsafe” ear requires surgical treatment. High resolution CT is the method of choice for imaging cholesteatoma, but it cannot differentiate cholesteatoma from other soft tissues or mucoid secretions, especially in patients who have previous surgery, thus diffusion weighted MRI (DW-MRI) is recently used for differentiating cholesteatoma from other pathologies. Objectives: We aimed to evaluate the role of DW-MRI in diagnosis of de novo and recurrent cholesteatoma. Patients and Methods: We enrolled forty patients with suspected cholesteatoma either de novo or recurrent. All patients were subjected to complete history taking, otoscopic examination, HRCT scan and DW- MRI scanning with calculation of the apparent diffusion co-efficient (ADC). Then, surgical exploration of the middle ear was done, and we correlated between the operative and DW-MRI results. Results: We found ADC values ranged between 0.1-1.7 with median ADC value was 0.8 mm 2 /s. ADC cut-off point for detecting cholesteatoma was 0.8. P values for ADC, were significant for both denovo and recurrent cases, 0.044 and 0.039 respectively. Also, we found that DW-MRI had a sensitivity of (83%), specificity (75%), PPV (88%), NPV (67%) for detection of cholesteatoma in de novo cases, and a sensitivity of (80%), specificity (75%), PPV (89%) and NPV (60%) for recurrent cases. Conclusion: DW-MRI could be a sensitive non-invasive tool for detecting cholesteatoma.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80019785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Articulation Disorders on Interpretation of Word Recognition Scores in Hearing Impaired Children with Cochlear Implant","authors":"A. Morgan, Amira Salah Elhwary, Ayman Amer, Mohamed Abd El-Tawwab","doi":"10.21608/ejentas.2021.56874.1302","DOIUrl":"https://doi.org/10.21608/ejentas.2021.56874.1302","url":null,"abstract":"Objectives: Speech recognition tests are used to explain the accuracy of patient auditory reception and processing of speech material. There will be a problem when testing children because their speech recognition scores are affected by their level of language development and their auditory capabilities. This prospective study was designed to compare word recognition test scores -Arabic version- before and after phoniatric evaluation and application of Arabic articulation test in children using cochlear implant aiming at evaluating effect of articulation disorders on interpretation of word recognition scores. Methods: Forty-six children enrolled in Med El cochlear implant program divided into 4 groups according to language assessment. Aided word recognition test was performed before and after application of Arabic articulation test that detects speech and articulation errors including substitution, phonological processes, right words and wrong words. Results: Scores of word recognition test of study groups were improved after phoniatric evaluation and application of articulation test and reflected the importance of duration of language rehabilitation and use of cochlear implant. Conclusion: Speech production errors could contaminate the results of open-set speech perception tests and the application of standardized articulation test aids in real estimation of word recognition in children with cochlear implant.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87090322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta Analytical Study of the Role of Intramuscular Botulinum A Toxin Injection in the Treatment of Temporomandibular Joint (TMJ) Disorders","authors":"Ayman El-Kahky, T. Hamdy, Mohamed S. El-Tantawy, A. Askoura","doi":"10.21608/ejentas.2022.167208.1567","DOIUrl":"https://doi.org/10.21608/ejentas.2022.167208.1567","url":null,"abstract":"Introduction: Botulinum toxin is a neurotoxin produced by a gram-positive, anaerobic spore-forming bacterium called Clostridium botulinum recently used as an effective and safe line of treatment for the temporomandibular joint disorders (TMDs) through temporarily inhibition of the masticatory muscles. TMDs is a collective non-specific term used to describe disorders that involve the TMJ, masticatory muscles and/or associated structures. Aim of the Work: A meta-analysis was conducted to evaluate the efficacy of intramuscular Botulinum toxin-A injection (BTX-A) in the treatment of myogenic temporomandibular joint (TMJ) disorders. Patients and Methods: A systematic literature search was done to identify relevant studies published within the last 25 years on humans. Literature search had been done including PubMed, Medline, Scopus, Web of science, EBSCOhost and Cochrane databases. The study included published medical articles about intramuscular botulinum toxin-A injection in patients suffering from myogenic TMD. The results of the similar studies were pooled in the meta-analysis. Results: Thirty-nine studies with 1538 participants were included in our systematic review and 23 of these studies were pooled in the meta-analysis. The current study showed that the difference of VAS (visual analogue scale) score at 1 and 3 months associated with intramuscular BTX-A injection (pre- and post-treatment) and BTX-A versus control is statistically significant. The difference of MMO (maximum mouth opening) at 1 and 3 months between BTX-A and control is not statistically significant. The difference of EMG amplitude at 1 month between BTX-A and control is not statistically significant while at 3 months is statistically significant. The change in maximum bite force at 3 and 6 months between BTX-A and control is statistically significant. Conclusion: The available data favors the efficacy of usage of intramuscular BTX-A injection in cases of myogenic TMD, further randomized controlled studies must be conducted in the future.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81796420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curcumin Enhanced the Anti-proliferative Effect of Cetixumab Through TRPV1 Channels in Human Larynx Cancer Cells","authors":"H. Gunizi, O. Gunizi, I. Ovey","doi":"10.21608/ejentas.2022.111505.1448","DOIUrl":"https://doi.org/10.21608/ejentas.2022.111505.1448","url":null,"abstract":"","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86729499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vestibular & Balance Assessment in Hepatitis C Virus Patients Undergoing (Sovaldi/Daklinza) Regimen","authors":"Aya Elhusseiny, A. Shalaby, H. Taha, O. Ahmed","doi":"10.21608/ejentas.2021.69389.1339","DOIUrl":"https://doi.org/10.21608/ejentas.2021.69389.1339","url":null,"abstract":"Department of 1,2,3Audiology, E.N.T, 4Internal Medicine, Hepatogastroenterology Unit, Faculty of Medicine, Ain Shams University, Egypt. ABSTRACT Background: Previous Hepatitis C Virus (HCV) antiviral drugs reported to cause ototoxicity. Aim: To detect any possible adverse effects of Sovaldi/ Daklinza regimen related to vestibular & balance functions. Patients and Methods: Vestibular & balance were assessed in a total number of thirty adult HCV patients , ranging from twenty to sixty years old before administration of (Sovaldi/Daklinza) and three months later , using Vestibular office tests (Head shake test, Head thrust test, Fukuda stepping test& one leg stance). Videonystagmography (VNG), Sensory organization test (SOT) of Dynamic posturagraphy. Results: After treatment, all patients had normal vestibular office tests, normal VNG testing except for three patients (10% of the study sample) showed positional nystagmus after treatment that wasn’t present before receiving Sovaldi/ Daclinza & normal balance function as demonstrated by SOT of Dynamic posturagraphy, with non-statistical significant difference when comparing before and after treatment findings. Conclusion: Sovaldi/Daklinza regimen used in HCV treatment has no statistically significant effect on vestibular & balance function.","PeriodicalId":37983,"journal":{"name":"Egyptian Journal of Ear, Nose, Throat and Allied Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91349225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}