Arthroplasty Today最新文献

{"title":"Corrigendum to “Revision Rates for Aseptic Loosening in the Obese Patient: A Comparison Between Stemmed, Uncemented, and Unstemmed Tibial Total Knee Arthroplasty Components” [Arthroplasty Today 32 (2025) 101,621]","authors":"Bernard H. van Duren, Amy M. Firth, Reshid Berber, Hosam E. Matar, Peter J. James, Benjamin V. Bloch","doi":"10.1016/j.artd.2025.101683","DOIUrl":"10.1016/j.artd.2025.101683","url":null,"abstract":"","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101683"},"PeriodicalIF":1.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking Gait Analysis Beyond the Gait Lab: High-Fidelity Replication of Knee Kinematics Using Inertial Motion Units and a Convolutional Neural Network","authors":"Stefano A. Bini MD ,&nbsp;Nicholas Gillian PhD ,&nbsp;Thomas A. Peterson PhD ,&nbsp;Richard B. Souza PhD, PT ,&nbsp;Brooke Schultz MS, ACE-CPT ,&nbsp;Wojciech Mormul MS ,&nbsp;Marek K. Cichoń MS ,&nbsp;Agnieszka Barbara Szczotka MS ,&nbsp;Ivan Poupyrev PhD","doi":"10.1016/j.artd.2025.101656","DOIUrl":"10.1016/j.artd.2025.101656","url":null,"abstract":"<div><h3>Background</h3><div>Gait analysis using three-dimensional motion capture systems (3D motion capture) provides a combination of kinematic and kinetic measurements for quantifying and characterizing the motion and loads, respectively, of lower extremity joints during human movement. However, their high cost and limited accessibility impact their utility. Wearable inertial motion sensors offer a cost-effective alternative to measure simple temporospatial variables, but more complex kinematic variables require machine learning interfaces. We hypothesize that kinematic measures about the knee collected using motion capture can be replicated by coupling raw data collected from inertial measurement units (IMUs) to machine learning algorithms.</div></div><div><h3>Methods</h3><div>Data from 40 healthy participants performing fixed walking, stair climbing, and sit-to-stand tasks were collected using both 3D motion capture and IMUs. Sequence to sequence convolutional neural networks were trained to map IMU data to three motion capture kinematic outputs: right knee angle, right knee angular velocity, and right hip angle. Model performance was assessed using mean absolute error.</div></div><div><h3>Results</h3><div>The convolutional neural network models exhibited high accuracy in replicating motion capture-derived kinematic variables. Mean absolute error values for right knee angle ranged from 4.30 ± 1.55 to 5.79 ± 2.93 degrees, for right knee angular velocity from 7.82 ± 3.01 to 22.16 ± 9.52 degrees per second, and for right hip angle from 4.82 ± 2.29 to 8.63 ± 4.73 degrees. Task-specific variations in accuracy were observed.</div></div><div><h3>Conclusions</h3><div>The findings highlight the potential of leveraging raw data from wearable inertial sensors and machine learning algorithms to reproduce gait lab-quality kinematic data outside the laboratory settings for the study of knee function following joint injury, surgery, or the progression of joint disease.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101656"},"PeriodicalIF":1.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Factors for Return to Driving After Lower Limb Arthroplasty","authors":"Vasileios Giannoudis MBChB, MRes ,&nbsp;Katie Lee BSc ,&nbsp;Farag Shuweihdi PhD ,&nbsp;Andrew Manktelow MBBS, BSc, FRCS(Ed), FRCS(Orth) ,&nbsp;Benjamin Bloch BSc, MBBS, FRCS (Tr & Orth) ,&nbsp;Bernard van Duren BEng, MBChB, DPhil, CEng, FIMechE, FRCS ,&nbsp;Hemant Pandit FRCS (Orth), D Phil (Oxon)","doi":"10.1016/j.artd.2025.101685","DOIUrl":"10.1016/j.artd.2025.101685","url":null,"abstract":"<div><h3>Background</h3><div>A common question post total hip arthroplasty (THA)/total knee arthroplasty (TKA) arthroplasty is “Doctor, when can I drive?”. No objective assessment currently exists. This study aimed to identify clinical factors predicting driving return post hip THA and TKA.</div></div><div><h3>Methods</h3><div>In this single-center retrospective observational study, patients were reviewed at 6 weeks post THA and TKA. Patient demographics, driving status, timed up and go (TUG) test, self-reported walking time (SRWT), walking aid use, and pain scores were collected. Descriptive statistics, <em>t</em>-tests, and binary regression models were used.</div></div><div><h3>Results</h3><div>Five hundred ninety two participants were included: 271 THA (males n = 134, mean age: 66.4) and 321 TKA (males n = 155, mean age: 66.8). THA: At 6 weeks, 155 patients (57.1%) were driving and 116 did not drive (DND) (n = 82 female, 70.6%) (<em>P</em> &lt; .001). SRWT was longer in driving group (mean 36.35 minutes vs 31.23 minutes [<em>P</em> = .072]). TUG tests were faster in driving group (9.51 seconds vs 11.98 seconds [<em>P</em> &lt; .001]). Driving inability predictors included using 2 crutches (<em>P</em> &lt; .001) and TUG (<em>P</em> = .015). TKA: At 6 weeks, 196 patients (61%) were driving and 125 DND (n = 78 female, 62.4%) (<em>P</em> &lt; .01). SRWT was longer in driving group (mean 33.6 vs 28.1 minutes [<em>P</em> = .31]). TUG tests were faster in driving group (10.18 seconds vs 12.29 seconds [<em>P</em> &lt; .001]). Driving inability predictors included “severe” pain scores (<em>P</em> ≤ .0001) and &gt;2 walking aids use (<em>P</em> = .022).</div></div><div><h3>Conclusions</h3><div>Following THA/TKA, 60% patients were driving by 6 weeks. Females take longer for driving return. Walking aids negatively impacted driving return, while faster TUG test and longer SRWT were positive predictors.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101685"},"PeriodicalIF":1.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Failure of a Novel Modular Dual Mobility Liner After Metal Release: Clinical Presentation and Detailed Retrieval Analysis","authors":"Allan K. Metz MD ,&nbsp;Michael A. Kurtz PhD ,&nbsp;Cameron R. Egan MD ,&nbsp;Steven M. Kurtz PhD ,&nbsp;Christopher E. Pelt MD","doi":"10.1016/j.artd.2025.101687","DOIUrl":"10.1016/j.artd.2025.101687","url":null,"abstract":"<div><div>Cobalt chrome alloy (CoCrMo) corrosion and subsequent metal release has been described as a potential complication of total hip arthroplasty. Here, we present the case of a patient with a well-seated dual mobility (DM) implant revised after 10 months. Prior to revision, the patient experienced pain and stiffness. Following a negative infection workup, we measured elevated metal concentrations, hypothesized to originate from the CoCrMo DM liner. While corrosion has been extensively reported in other constructs, the CoCrMo liner described here includes a post and tabs, features added to reduce the risk of corrosion. Retrieval analysis demonstrated a severe chemically based corrosion attack on the liner. Continued caution and ongoing close monitoring of outcomes associated with the use of modular DM constructs is likely warranted.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101687"},"PeriodicalIF":1.5,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral Instability 13 Years After Kinematically Aligned Total Knee Arthroplasty","authors":"Oliver Haider ,&nbsp;Tobias Scheidl ,&nbsp;Christian Manuel Sterneder MD ,&nbsp;Friedrich Boettner MD","doi":"10.1016/j.artd.2025.101674","DOIUrl":"10.1016/j.artd.2025.101674","url":null,"abstract":"<div><div>To reduce unsatisfied patients following total knee arthroplasty (TKA), kinematic alignment has been introduced as an alternative to mechanical alignment. Studies have shown no significant differences in functional outcomes and early revision rates between alignment strategies. This case report presents a 64-year-old patient who developed progressive varus alignment and lateral instability 13 years after a kinematically aligned TKA. The case highlights the impact of varus alignment on the risk of medial plastic wear and lateral soft tissue attenuation. Both can contribute to lateral instability, a lateral thrust, and progressive varus deformity in unrestricted kinematic alignment TKA. This article suggests that excessive varus alignment should be avoided and restricted alignment targets should be considered when using kinematic, or functional alignment in TKA for varus osteoarthritis.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101674"},"PeriodicalIF":1.5,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143821531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revision Hip Arthroplasty Through a Gluteal-Sparing Extended Posterior Approach May be Able to Achieve Similar Functional Outcomes to Primary Hip Arthroplasty","authors":"Dominic Thewlis PhD ,&nbsp;Jasvir Bahl PhD ,&nbsp;Hao Wei (Harvey) Chai MBBS ,&nbsp;Stuart A. Callary PhD ,&nbsp;Thomas M. Grace PhD ,&nbsp;John B. Arnold PhD ,&nbsp;Mark Taylor PhD ,&nbsp;Lucian B. Solomn MD, FRCAS, PhD","doi":"10.1016/j.artd.2025.101681","DOIUrl":"10.1016/j.artd.2025.101681","url":null,"abstract":"<div><h3>Background</h3><div>Revision total hip arthroplasty (THA) has been reported to have worse outcomes when compared to primary procedures, which may, in part, be due to the increased exposure required for the procedure. We aimed to investigate the postoperative functional outcomes of 2 groups of primary and revision THA, when revision procedures were performed using a gluteal-sparing extended posterior approach.</div></div><div><h3>Methods</h3><div>Two groups of 51 primary and 21 revision THAs were prospectively recruited from a single center between 2016 and 2019. Both groups were assessed preoperatively using quantitative gait analysis and patient-reported outcomes, and at 3 and 12 months postoperatively. Hip and knee kinematics were computed from motion capture data acquired at the gait analysis. Kinematic and patient-reported outcome measures data were analyzed using linear mixed models. Statistical parametric analysis complemented the main analysis of the kinematics.</div></div><div><h3>Results</h3><div>Patients in the primary group had worse preoperative patient-reported outcome measures when compared to the revision group. There were no between-group differences in walking speed. Hip extension in late stance phase of gait was 9° and 5° lower for the revision group when compared to the primary group at 3 and 12 months, respectively. These differences were not statistically significant, but the magnitude of the effect size was noteworthy suggesting a functional deficit (Cohen’s <em>d</em> = 0.64 and 0.54, respectively).</div></div><div><h3>Conclusions</h3><div>Revision THA using a gluteal-sparing extended posterior approach may be able to achieve similar patient-reported and gait outcomes with those of primary THA within the first 12 postoperative months.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101681"},"PeriodicalIF":1.5,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved Efficiency and Intraoperative Planning With 1 Robot-Assisted Total Knee Arthroplasty System","authors":"Dalton L. Braathen BS,&nbsp;Cameron Wallace MD,&nbsp;Ian M. Clapp MD, MS,&nbsp;Brenna E. Blackburn PhD,&nbsp;Christopher L. Peters MD,&nbsp;Michael J. Archibeck MD","doi":"10.1016/j.artd.2025.101684","DOIUrl":"10.1016/j.artd.2025.101684","url":null,"abstract":"<div><h3>Background</h3><div>Robotic-assisted total knee arthroplasty (rTKA) has garnered significant interest for its potential to enhance surgical precision and accuracy. However, the adoption of such systems poses concerns, including longer operative times and learning curves, potentially reducing efficiency. This study aimed to evaluate the learning curve associated with the Robotic Surgical Assistant (ROSA) system for rTKA.</div></div><div><h3>Methods</h3><div>This retrospective review analyzed the first 75 ROSA rTKA procedures performed by each of 2 fellowship-trained arthroplasty surgeons (150 total procedures) at a high-volume institution. Time stamps within the robotic software were recorded for each case, along with tourniquet time. Statistical analyses included descriptive statistics, <em>t</em>-tests, and multilevel regression.</div></div><div><h3>Results</h3><div>Comparison of each surgeon's first 20 and last 20 cases revealed significant decreases in tourniquet time (61.4-56.7 minutes; <em>P</em> = .0417) and planning time (13.49-6.68 minutes; <em>P</em> = .0078). Landmark femur and tibia times remained stable (<em>P</em> = .6542 and <em>P</em> = .9440). Knee state evaluation time showed a trend of reduction from 9.22 to 7.33 minutes (<em>P</em> = .1335), and resection time from 13.66 to 12.92 minutes (<em>P</em> = .4372). Regression analysis indicated significant reductions in tourniquet time (β = −0.11; <em>P</em> = .0089) and planning time (β = −0.08; <em>P</em> = .0064).</div></div><div><h3>Conclusions</h3><div>This study demonstrates that execution of ROSA rTKA becomes more efficient over the first 75 cases. The greatest improvement with experience is the time spent on the planning panel, the cognitive portion of the procedure. These data provide surgeons with the confidence that the technical portions of the case are quick to learn and guide industry to focus on teaching effective adjustments on the planning panel.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101684"},"PeriodicalIF":1.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Mass Index as a Risk Factor for Readmission Rates in Direct Anterior Approach Total Hip Arthroplasty","authors":"Evan R. Simpson BS ,&nbsp;Parke Hudson MD ,&nbsp;Viraj Deshpande BS ,&nbsp;Sean Guerrero MHA ,&nbsp;Steven Barnett MD ,&nbsp;Matthew P. Siljander MD","doi":"10.1016/j.artd.2025.101679","DOIUrl":"10.1016/j.artd.2025.101679","url":null,"abstract":"<div><h3>Background</h3><div>Multiple studies have examined the relationship between obesity and increased risk of perioperative complications in patients undergoing total hip arthroplasty (THA). The purpose of this study was to compare the rate of perioperative complications stratified by body mass index (BMI) in patients undergoing THA through a direct anterior (DA) approach.</div></div><div><h3>Methods</h3><div>A retrospective review at a single high-volume orthopaedic specialty hospital identified all DA THAs performed between January 2019 and August 2022. Patients were stratified by BMI into the following cohorts: underweight (BMI&lt;18.5), normal (BMI = 18.5-25), overweight (BMI = 25-30), obese class I (BMI = 30-35), obese class II (BMI = 35-39.9), and obese class III (BMI ≥ 40). Primary outcomes collected included 30-day and 90-day readmissions, emergency department visits, intraoperative fracture, and 90-day infection requiring return to the operating room. There were 4767 patients with a mean BMI of 28 kg/m² (15.5-54.5) and a mean age of 67 years (18-100 years).</div></div><div><h3>Results</h3><div>Thirty-day readmission rates in the obese class III (6.2%) were significantly higher when compared individually to all other cohorts (<em>P</em> &lt; .001). Additionally, logistic regression found that underweight patients had an increased likelihood of an intraoperative fracture (odds ratio [OR]: 13.120, 95% confidence interval [CI]: 1.172-146.930, <em>P</em> &lt; .001), and both obese classes I and III were more likely to have a 90-day infection that required a return to the operating room (OR: 8.508, 95% CI: 1.023-70.779, <em>P</em> &lt; .001 and OR: 29.853, 95% CI: 2.683-332.187, <em>P</em> &lt; .001, respectively).</div></div><div><h3>Conclusions</h3><div>Obese class III patients have a higher rate of 30-day readmission following DA THA than all other BMI cohorts and are at increased risk of infection requiring return to the operating room when compared to patients with normal BMI. Surgeons should counsel patients regarding the increased potential complication risks related to BMI.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101679"},"PeriodicalIF":1.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143769344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Times are Changing!","authors":"Brett R. Levine MD, MS (Editor-in-Chief)","doi":"10.1016/j.artd.2025.101678","DOIUrl":"10.1016/j.artd.2025.101678","url":null,"abstract":"","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"32 ","pages":"Article 101678"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Malnutrition on Perioperative Outcomes of Total Hip Arthroplasty: A Systematic Review and Meta-Analysis","authors":"Adam Aziz BA ,&nbsp;James B. Bluhm BS ,&nbsp;Tyler K. Williamson DO ,&nbsp;Cameron Atkison MD ,&nbsp;Andrew Eck MD ,&nbsp;Chance Moore MD ,&nbsp;Frank A. Buttacavoli MD","doi":"10.1016/j.artd.2025.101667","DOIUrl":"10.1016/j.artd.2025.101667","url":null,"abstract":"<div><h3>Background</h3><div>Malnutrition can play a significant role in wound healing, immune response, and conditioning. The purpose of this review is to characterize definitions of malnutrition in total hip arthroplasty (THA) and analyze its effects on postoperative outcomes.</div></div><div><h3>Methods</h3><div>A systematic search was conducted using iterations of the key terms “total hip arthroplasty” and “malnutrition.” Human studies describing malnutrition in patients undergoing primary THA for either traumatic or elective indications were included. Using the SPSS meta-analysis binary and continuous model function, the mean effect size estimate (MSE) or Cohen’s d (Cd) statistic with 95% confidence interval was reported.</div></div><div><h3>Results</h3><div>This search yielded a total of 555 studies, of which 9 articles comprising 495,657 patients undergoing primary THA were included, characterizing 16,895 patients (3.4%) as malnourished. Studies characterized malnutrition as albumin &lt;3.5 g/dL (n = 7) and total lymphocyte count &lt;1500 (n = 1). Malnutrition was associated with an increased rate of nonhome discharge (MSE = 0.81, [0.55-1.07]) and likelihood of readmission (MSE = 0.86, [0.75-0.97]). Malnutrition at the time of surgery was also associated with increased rates of any complication (MSE = 1.01, [0.46-1.57]), wound complications (MSE = 1.04, [0.72-1.36]), pulmonary complications (MSE = 1.54, [1.29-1.78]), need for transfusion (MSE = 0.75, [0.54-0.96]), periprosthetic fracture (MSE = 0.65, [0.47-0.82]), reoperation (MSE = 0.72, [0.58-0.86]), and perioperative mortality (MSE = 2.05, [1.76-2.33]).</div></div><div><h3>Conclusions</h3><div>Malnutrition was found to have significant associations with complications and disposition following THA. The findings from this meta-analysis provide support for further investigation into perioperative nutritional supplementation strategies for surgeons to optimize at-risk patients prior to THA.</div></div><div><h3>Level of Evidence</h3><div>III.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"33 ","pages":"Article 101667"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143737819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}