Evan P. Johnson MD , Nicholas M. Brown MD , Michael D. Hellman MD , Tyler E. Calkins MD , Nuanqiu Hou MS , John R. Crockarell MD , James L. Guyton MD , Christopher T. Holland MD, MS , William M. Mihalko MD, PhD , Marcus C. Ford MD
{"title":"全膝关节置换术中关节软骨深度的验证","authors":"Evan P. Johnson MD , Nicholas M. Brown MD , Michael D. Hellman MD , Tyler E. Calkins MD , Nuanqiu Hou MS , John R. Crockarell MD , James L. Guyton MD , Christopher T. Holland MD, MS , William M. Mihalko MD, PhD , Marcus C. Ford MD","doi":"10.1016/j.artd.2025.101869","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Understanding cartilage thickness is critical for execution of an unrestricted, calipered kinematic total knee arthroplasty (TKA). Historically, condylar cartilage was assumed to be 2 mm thick. However, thickness may vary based on age, sex, body mass index, anterior cruciate ligament (ACL) status, and alignment. This study aimed to determine in vivo cartilage thickness in patients undergoing TKA and evaluate which factors affect variation. Our hypothesis was in vivo cartilage thickness would be 2 mm on average, but some patients would have greater than 2 mm based on demographic factors.</div></div><div><h3>Methods</h3><div>This multicenter, prospective cross-sectional cohort study evaluated condyle cartilage thickness from resected fragments. Univariate statistics and general linear models were used.</div></div><div><h3>Results</h3><div>Among 806 TKA cases, the mean unworn femoral cartilage thickness was as follows: distal medial 2.0 mm; distal lateral 2.2 mm; posterior medial 2.0 mm; and posterior lateral 2.2 mm. The mean unworn tibia cartilage thickness was as follows: medial spine 2.4 mm; medial center 1.4 mm; lateral spine 2.1 mm; and lateral center 2.5 mm. In patients with unworn femoral cartilage, approximately 18.5% had cartilage greater than 3 mm. In patients with unworn tibial cartilage, approximately 34.7% had cartilage greater than 3 mm. An incompetent ACL was correlated with thinner posteromedial femoral cartilage. Increased thickness was correlated with younger age, men.</div></div><div><h3>Conclusions</h3><div>A subset had unworn cartilage thickness greater than 3.0 mm, supporting our hypothesis. In an ACL deficient knee, the posteromedial cartilage was partially worn and should be considered for MCL isometry. Significant correlations were found based on age, gender, ACL status, alignment, body mass index, and race.</div></div><div><h3>Level of Evidence</h3><div>Level 2, Prospective cohort study.</div></div>","PeriodicalId":37940,"journal":{"name":"Arthroplasty Today","volume":"35 ","pages":"Article 101869"},"PeriodicalIF":2.1000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Validation of Articular Cartilage Depth in Total Knee Arthroplasty\",\"authors\":\"Evan P. Johnson MD , Nicholas M. Brown MD , Michael D. Hellman MD , Tyler E. Calkins MD , Nuanqiu Hou MS , John R. Crockarell MD , James L. Guyton MD , Christopher T. Holland MD, MS , William M. Mihalko MD, PhD , Marcus C. Ford MD\",\"doi\":\"10.1016/j.artd.2025.101869\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Understanding cartilage thickness is critical for execution of an unrestricted, calipered kinematic total knee arthroplasty (TKA). Historically, condylar cartilage was assumed to be 2 mm thick. However, thickness may vary based on age, sex, body mass index, anterior cruciate ligament (ACL) status, and alignment. This study aimed to determine in vivo cartilage thickness in patients undergoing TKA and evaluate which factors affect variation. Our hypothesis was in vivo cartilage thickness would be 2 mm on average, but some patients would have greater than 2 mm based on demographic factors.</div></div><div><h3>Methods</h3><div>This multicenter, prospective cross-sectional cohort study evaluated condyle cartilage thickness from resected fragments. Univariate statistics and general linear models were used.</div></div><div><h3>Results</h3><div>Among 806 TKA cases, the mean unworn femoral cartilage thickness was as follows: distal medial 2.0 mm; distal lateral 2.2 mm; posterior medial 2.0 mm; and posterior lateral 2.2 mm. The mean unworn tibia cartilage thickness was as follows: medial spine 2.4 mm; medial center 1.4 mm; lateral spine 2.1 mm; and lateral center 2.5 mm. In patients with unworn femoral cartilage, approximately 18.5% had cartilage greater than 3 mm. In patients with unworn tibial cartilage, approximately 34.7% had cartilage greater than 3 mm. An incompetent ACL was correlated with thinner posteromedial femoral cartilage. Increased thickness was correlated with younger age, men.</div></div><div><h3>Conclusions</h3><div>A subset had unworn cartilage thickness greater than 3.0 mm, supporting our hypothesis. In an ACL deficient knee, the posteromedial cartilage was partially worn and should be considered for MCL isometry. Significant correlations were found based on age, gender, ACL status, alignment, body mass index, and race.</div></div><div><h3>Level of Evidence</h3><div>Level 2, Prospective cohort study.</div></div>\",\"PeriodicalId\":37940,\"journal\":{\"name\":\"Arthroplasty Today\",\"volume\":\"35 \",\"pages\":\"Article 101869\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arthroplasty Today\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352344125002560\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arthroplasty Today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352344125002560","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Validation of Articular Cartilage Depth in Total Knee Arthroplasty
Background
Understanding cartilage thickness is critical for execution of an unrestricted, calipered kinematic total knee arthroplasty (TKA). Historically, condylar cartilage was assumed to be 2 mm thick. However, thickness may vary based on age, sex, body mass index, anterior cruciate ligament (ACL) status, and alignment. This study aimed to determine in vivo cartilage thickness in patients undergoing TKA and evaluate which factors affect variation. Our hypothesis was in vivo cartilage thickness would be 2 mm on average, but some patients would have greater than 2 mm based on demographic factors.
Methods
This multicenter, prospective cross-sectional cohort study evaluated condyle cartilage thickness from resected fragments. Univariate statistics and general linear models were used.
Results
Among 806 TKA cases, the mean unworn femoral cartilage thickness was as follows: distal medial 2.0 mm; distal lateral 2.2 mm; posterior medial 2.0 mm; and posterior lateral 2.2 mm. The mean unworn tibia cartilage thickness was as follows: medial spine 2.4 mm; medial center 1.4 mm; lateral spine 2.1 mm; and lateral center 2.5 mm. In patients with unworn femoral cartilage, approximately 18.5% had cartilage greater than 3 mm. In patients with unworn tibial cartilage, approximately 34.7% had cartilage greater than 3 mm. An incompetent ACL was correlated with thinner posteromedial femoral cartilage. Increased thickness was correlated with younger age, men.
Conclusions
A subset had unworn cartilage thickness greater than 3.0 mm, supporting our hypothesis. In an ACL deficient knee, the posteromedial cartilage was partially worn and should be considered for MCL isometry. Significant correlations were found based on age, gender, ACL status, alignment, body mass index, and race.
期刊介绍:
Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.