Current Sleep Medicine Reports最新文献

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The Role of Chronopsychiatry in Precision Medicine: Circadian Dysregulation as Diagnostic Marker and Therapeutic Target. 时间精神病学在精准医学中的作用:昼夜节律失调作为诊断标志和治疗靶点。
IF 2
Current Sleep Medicine Reports Pub Date : 2026-01-01 Epub Date: 2026-02-20 DOI: 10.1007/s40675-026-00357-z
Aswathy B Suseela Devi, Katherine Lyman, Colleen A McClung
{"title":"The Role of Chronopsychiatry in Precision Medicine: Circadian Dysregulation as Diagnostic Marker and Therapeutic Target.","authors":"Aswathy B Suseela Devi, Katherine Lyman, Colleen A McClung","doi":"10.1007/s40675-026-00357-z","DOIUrl":"https://doi.org/10.1007/s40675-026-00357-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>Chronopsychiatry refers to a research and clinical approach which studies psychiatric illness through the lens of circadian rhythms and aims to reset the body's biological clock to counteract circadian rhythm abnormalities in psychiatric disorders. This review highlights the use of circadian biomarkers collected from wearable devices and other methods to help the development of personalized treatment plans based on patients' individual circadian functioning. Circadian biomarkers, such as activity, heart rate, skin temperature, and light exposure recorded over 24 h, has shown promise in diagnosing and assessing the severity of various neuropsychiatric disorders.</p><p><strong>Recent findings: </strong>Wearable devices capable of recording multiple circadian parameters have greatly aided data collection, and when integrated into treatment, have shown promise for revolutionizing circadian medicine. Therapies that entrain or shift the circadian system can help stabilize sleep-wake rhythms or better align rhythms with the environment.</p><p><strong>Summary: </strong>These approaches support the emerging field of precision psychiatry, moving beyond a one-size-fits-all approach and addressing the heterogeneity and complexity of psychiatric disorders.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"12 1","pages":"1"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12923476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behavioral Sleep Therapies During the Perinatal Period: A Scoping Review. 围产期行为睡眠疗法:范围综述。
IF 2
Current Sleep Medicine Reports Pub Date : 2026-01-01 Epub Date: 2026-03-03 DOI: 10.1007/s40675-026-00359-x
Jennifer N Felder, Bernadette McClelland, Candance Sorensen, Meghan Brown, Richelle Mah
{"title":"Behavioral Sleep Therapies During the Perinatal Period: A Scoping Review.","authors":"Jennifer N Felder, Bernadette McClelland, Candance Sorensen, Meghan Brown, Richelle Mah","doi":"10.1007/s40675-026-00359-x","DOIUrl":"https://doi.org/10.1007/s40675-026-00359-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>Perinatal insomnia is common and consequential. This review presents findings from randomized controlled trials of behavioral sleep therapies in perinatal samples published since 2020.</p><p><strong>Recent findings: </strong>Eleven studies were included; seven investigated cognitive behavioral therapy for insomnia (CBT-I) and four investigated mindfulness-based interventions (MBI). CBT-I is effective for improving perinatal sleep. Benefits attenuate in the early postpartum period, and re-emerge around six months postpartum. Impact on mental health outcomes is mixed, possibly due to variations in comparator groups and assessment timepoints. Two of the MBI trials were adequately powered to investigate effects on insomnia severity, and suggest that MBIs may be effective for reducing insomnia during pregnancy.</p><p><strong>Summary: </strong>Future work should evaluate the effectiveness of behavioral sleep therapies in real world settings, examine benefits beyond six months postpartum, evaluate impacts on offspring, conduct rigorous research to better quantify mental health benefits, and elucidate for whom MBI is indicated vs. CBT-I.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"12 1","pages":"5"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12953425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Evidence for Sleep States in Drosophila: Findings and Implications. 果蝇睡眠状态的最新证据:发现和启示。
IF 2
Current Sleep Medicine Reports Pub Date : 2026-01-01 Epub Date: 2026-03-27 DOI: 10.1007/s40675-025-00352-w
Maria E Colt, Susan T Harbison
{"title":"Current Evidence for Sleep States in <i>Drosophila</i>: Findings and Implications.","authors":"Maria E Colt, Susan T Harbison","doi":"10.1007/s40675-025-00352-w","DOIUrl":"10.1007/s40675-025-00352-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Sleep is an essential biological behavior, with its absence leading to severe consequences, including death. In mammals, sleep consists of distinct states-such as REM and non-REM-that are often thought to serve different physiological functions. Traditionally, <i>Drosophila melanogaster</i> were believed to experience sleep as a single, unitary state. However, recent research suggests that sleep in flies is more complex than previously understood and can be divided into distinct states. This raises the possibility that the fly model can be used to investigate the functional role(s) of each sleep state.</p><p><strong>Recent findings: </strong>In this review, we explore the behavioral, neurophysiological, metabolic, and transcriptional evidence supporting the existence of these sleep states in <i>Drosophila</i>. We assess whether consistent criteria can be established for these sleep states and propose a new direction for sleep research by identifying genetic correlates associated with these states.</p><p><strong>Summary: </strong>This approach has the potential to deepen our understanding of sleep architecture and its genetic underpinnings, offering insights that may extend beyond the <i>Drosophila</i> model to other species, including humans.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"12 1","pages":"14"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13031250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Better Sleep to Improved Mood: A Review of the Biopsychosocial Pathways for Cognitive Behavioral Therapy for Insomnia's Antidepressant Effects. 从改善睡眠到改善情绪:认知行为治疗失眠抗抑郁作用的生物心理社会途径综述。
IF 2
Current Sleep Medicine Reports Pub Date : 2026-01-01 Epub Date: 2026-04-30 DOI: 10.1007/s40675-026-00376-w
Ivan Vargas, Harrison Dickens, Arash Assar
{"title":"From Better Sleep to Improved Mood: A Review of the Biopsychosocial Pathways for Cognitive Behavioral Therapy for Insomnia's Antidepressant Effects.","authors":"Ivan Vargas, Harrison Dickens, Arash Assar","doi":"10.1007/s40675-026-00376-w","DOIUrl":"https://doi.org/10.1007/s40675-026-00376-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Recent research supports that Cognitive Behavioral Therapy for Insomnia (CBT-I) improves both insomnia and depression symptoms. The primary purpose of the current review was to summarize potential mechanistic pathways linking insomnia and depression while evaluating how improvements in sleep via CBT-I may lead to reduced depressive symptoms.</p><p><strong>Recent findings: </strong>The current literature supports that there are several potential biological, behavioral, and cognitive-affective mechanisms, including improved hypothalamic-pituitary-adrenal (HPA) axis and inflammatory functioning, behavioral activation, and emotion regulation, that may explain the antidepressant effects of CBT-I.</p><p><strong>Summary: </strong>Critically evaluating the potential mechanisms by which CBT-I improves depression (e.g., HPA-axis, inflammatory, behavioral, and emotional processes) will inform future efforts to enhance the overall effectiveness of CBT-I in patients with comorbid depression. Specifically, it will identify specific mechanisms that can be the focus of more targeted interventions or strategies to streamline CBT-I in patients with depression.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"12 1","pages":"21"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributions of Zebrafish to Our Understanding of the Function and Regulation of Sleep. 斑马鱼对我们理解睡眠功能和调节的贡献。
IF 2
Current Sleep Medicine Reports Pub Date : 2026-01-01 Epub Date: 2026-03-18 DOI: 10.1007/s40675-026-00361-3
Jin Xu, Olivia Eliopoulos, David A Prober
{"title":"Contributions of Zebrafish to Our Understanding of the Function and Regulation of Sleep.","authors":"Jin Xu, Olivia Eliopoulos, David A Prober","doi":"10.1007/s40675-026-00361-3","DOIUrl":"https://doi.org/10.1007/s40675-026-00361-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>Sleep is an essential behavioral state, but how and why animals sleep is poorly understood. These questions are being addressed using a variety of model systems, each with its own advantages and limitations. Here we review the contributions of zebrafish to our understanding of both mechanisms that regulate sleep and the functions of sleep.</p><p><strong>Recent findings: </strong>Initial zebrafish studies focused on defining sleep based on behavioral criteria and demonstrating that mechanisms that regulate mammalian sleep are conserved in zebrafish. More recent work, based on both specific hypothesis testing and large-scale screens, has provided novel insights into both mechanisms that regulate sleep and the functions of sleep. Studies using larval zebrafish showed that melatonin is essential for circadian regulation of sleep, and that both the serotonergic raphe and galanin play important roles in homeostatic regulation of sleep. These studies also identified the noradrenergic locus coeruleus as a hub that integrates wake- and sleep-promoting inputs to determine vigilance state. Work using zebrafish also revealed that repair of DNA damage is an important function of sleep, and provided support for the hypothesis that synaptic homeostasis is a function of sleep.</p><p><strong>Summary: </strong>Although the zebrafish was only recently developed as a sleep model and is used for this purpose by only a small number of labs, zebrafish studies have made important contributions to our understanding of both mechanisms that regulate sleep and functions of sleep. Based on recent advances in microscopy and genome editing technologies, studies using zebrafish are poised to provide important new insights into how and why animals sleep that would be difficult to achieve using other model systems.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"12 1","pages":"9"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12995953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep and circadian effects on the incretin system. 睡眠和昼夜节律对肠促胰岛素系统的影响。
IF 2
Current Sleep Medicine Reports Pub Date : 2025-12-01 Epub Date: 2025-05-28 DOI: 10.1007/s40675-025-00337-9
Robin K Yuan, Kirsi-Marja Zitting
{"title":"Sleep and circadian effects on the incretin system.","authors":"Robin K Yuan, Kirsi-Marja Zitting","doi":"10.1007/s40675-025-00337-9","DOIUrl":"10.1007/s40675-025-00337-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>Little is known about how incretins interact with sleep and circadian factors, both of which influence metabolic outcomes. We review evidence that sleep, circadian rhythms, and their disturbances impact incretin secretion and discuss clinical applications for GLP-1/GIP-RA drugs in sleep medicine and areas for future research.</p><p><strong>Recent findings: </strong>GLP-1 secretion exhibits a circadian rhythm which may be disrupted by high-fat diet, meal timing, and gut dysbiosis. Insufficient sleep may alter the timing of postprandial GLP-1 release, and the circadian rhythm of GLP-1 secretion is blunted in patients with metabolic conditions such as obesity or diabetes. Lastly, the FDA has approved the use of tirzepatide (a GLP-1/GIP-RA drug) for treating obstructive sleep apnea.</p><p><strong>Summary: </strong>Evidence suggests that sleep and circadian rhythms impact the incretin system, although findings are somewhat mixed due to the variety of methods employed. In light of the growing interest in new clinical applications for incretin therapies, more research is needed to fully understand the relationship between sleep, circadian rhythms, and incretin secretion.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Progress in Omics Studies of Sleep and Circadian Phenotypes. 睡眠与昼夜表型组学研究进展。
IF 1.5
Current Sleep Medicine Reports Pub Date : 2025-12-01 Epub Date: 2025-04-15 DOI: 10.1007/s40675-025-00335-x
Ziqing Wang, Tamar Sofer
{"title":"Recent Progress in Omics Studies of Sleep and Circadian Phenotypes.","authors":"Ziqing Wang, Tamar Sofer","doi":"10.1007/s40675-025-00335-x","DOIUrl":"https://doi.org/10.1007/s40675-025-00335-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>Sleep and circadian biology is fundamental to human health. Following the advancement in sleep medicine and availability of multi-omics technology, this review outlines the current knowledge regarding genetic basis and multi-omics research on circadian rhythm and the two most prevalent sleep disorders, obstructive sleep apnea (OSA) and insomnia.</p><p><strong>Recent findings: </strong>Genome wide association analyses identified variants across circadian genes and genes pertinent to inflammation, obesity and neuronal function associated with OSA and insomnia. Multi-omics integration has led to novel breakthroughs in identifying systemic biomarkers and elucidating cascades, and causal associations underpinning these complex traits.</p><p><strong>Summary: </strong>Multi-omics studies in sleep and circadian rhythm possess great potential in unveiling molecular mechanisms behind circadian rhythm and sleep, thereby advancing personalized medicine in the long term. Nevertheless, researchers should remain mindful of existing challenges in genetic and multi-omics sleep research, including data harmonization and existing racial and ethnic disparities in data collection and availability, limiting research generalizability.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SLEEP AND NEURODEGENERATION: EXAMINING POTENTIAL PHYSIOLOGICAL MECHANISMS. 睡眠和神经退化:检查潜在的生理机制。
IF 2
Current Sleep Medicine Reports Pub Date : 2025-12-01 Epub Date: 2025-01-03 DOI: 10.1007/s40675-024-00316-6
Brice V McConnell, Yulin Deng, Brendan P Lucey
{"title":"SLEEP AND NEURODEGENERATION: EXAMINING POTENTIAL PHYSIOLOGICAL MECHANISMS.","authors":"Brice V McConnell, Yulin Deng, Brendan P Lucey","doi":"10.1007/s40675-024-00316-6","DOIUrl":"10.1007/s40675-024-00316-6","url":null,"abstract":"<p><strong>Purpose of the review: </strong>The purpose of this review is to provide an overview of potential mechanisms mediating the bi-directional relationship between sleep and neurodegenerative diseases such as Alzheimer's disease. We provide updates on previously proposed mechanisms and identify new mechanisms particularly concerning how sleep disturbances affect memory-related neural circuits.</p><p><strong>Recent findings: </strong>In this review, we focus on the multiple mechanisms that potentially mediate the relationship between sleep and Alzheimer's disease. We present updates for previously hypothesized mechanisms such as sleep-related changes in production/release and clearance of amyloid-β and tau proteins as well as more recently proposed mechanisms relating to tau phosphorylation, the orexin system, astrocytes, and microglia. We also highlight how disruptions in sleep EEG oscillations that underlie memory-related neural circuits, such as slow wave activity, theta bursts, sleep spindles, and gamma ripples, change in Alzheimer's disease.</p><p><strong>Summary: </strong>Disturbed sleep increases Alzheimer's disease risk via multiple potential mechanisms that suggest multiple targets to test approved and effective treatments of sleep disorders to prevent or delay Alzheimer's disease.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian Rhythms in Aging and Age-Related Neurogenerative Disease. 衰老和年龄相关神经退行性疾病的昼夜节律。
IF 2
Current Sleep Medicine Reports Pub Date : 2025-12-01 Epub Date: 2025-05-17 DOI: 10.1007/s40675-025-00336-w
Kirsi-Marja Zitting, Robin K Yuan
{"title":"Circadian Rhythms in Aging and Age-Related Neurogenerative Disease.","authors":"Kirsi-Marja Zitting, Robin K Yuan","doi":"10.1007/s40675-025-00336-w","DOIUrl":"10.1007/s40675-025-00336-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Age-related changes in the circadian timing system may play a role in the development of disorders in older age. We review key aspects of the human circadian system that change with aging, discuss recent evidence of how changes in sleep and circadian rhythms manifest in neurodegenerative diseases, and summarize research on new therapies.</p><p><strong>Recent findings: </strong>Several mechanisms have been proposed to underlie age-related changes in sleep and circadian rhythmicity. These mechanisms include changes in the suprachiasmatic nucleus, melatonin production, and light sensitivity as well as impaired glymphatic drainage, buildup of amyloid-beta, hypoxia from sleep-disordered breathing, and increased levels of orexin. While light-based therapies and lifestyle interventions have been under investigation for years, newer interventions include treatment with orexin antagonists and gamma stimulation to improve sleep and circadian rhythmicity.</p><p><strong>Summary: </strong>Despite growing interest, our understanding of how sleep and circadian rhythms contribute to the development of age-related neurodegenerative diseases is still limited. More research is needed to understand the bidirectional relationship between circadian rhythms, sleep, and neurodegenerative diseases to develop targeted interventions.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daytime Napping in Adults: Benefits or Risks? Insights from Mendelian Randomization Studies. 成年人白天午睡:益处还是风险?孟德尔随机化研究的启示。
IF 2
Current Sleep Medicine Reports Pub Date : 2025-01-01 Epub Date: 2025-04-26 DOI: 10.1007/s40675-025-00333-z
Aarohi Gupta, Hassan S Dashti
{"title":"Daytime Napping in Adults: Benefits or Risks? Insights from Mendelian Randomization Studies.","authors":"Aarohi Gupta, Hassan S Dashti","doi":"10.1007/s40675-025-00333-z","DOIUrl":"10.1007/s40675-025-00333-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>Daytime napping, a brief sleep episode during the day, has mixed health effects. This review explores the relationship between daytime napping frequency and health outcomes by synthesizing results from published Mendelian randomization (MR) studies, which help mitigate confounding and reverse causality commonly observed in traditional epidemiological research.</p><p><strong>Recent findings: </strong>A total of 35 studies spanning seven major disease categories were identified, with cardiovascular, neurological, and metabolic outcomes being the most frequently investigated in MR. Of the 89 tested outcomes, 36% of studies suggested increased disease risk with more frequent daytime napping, 54% reported no associations, and 10% suggested decreased disease risk with more frequent daytime napping. Not all MR findings align with existing epidemiological research.</p><p><strong>Summary: </strong>The current evidence from MR does not provide a definitive conclusion regarding the health effects of daytime napping. Future research should consider additional dimensions of napping beyond frequency and integrate both genetic and non-genetic approaches in diverse populations.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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