Gabrielle F Gloston, Katherine C Ward, G Carolina Rodriguez-Torres, Karen L Gamble, S Justin Thomas
{"title":"Integrating Assessment of Circadian Rhythmicity to Improve Treatment Outcomes for Circadian Rhythm Sleep-Wake Disorders: Updates on New Treatments.","authors":"Gabrielle F Gloston, Katherine C Ward, G Carolina Rodriguez-Torres, Karen L Gamble, S Justin Thomas","doi":"10.1007/s40675-025-00325-z","DOIUrl":"10.1007/s40675-025-00325-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>Despite advancements in basic circadian research, development of new diagnostic and treatment strategies for circadian rhythm sleep-wake disorders (CRSWDs) has been slow. Here, we review the most recent innovations in human circadian assessment and emerging new therapies for CRSWDs.</p><p><strong>Recent findings: </strong>Researchers have improved existing circadian assessment methods to overcome logistical barriers and developed novel circadian assessment methods. New treatments for CRSWDs involve pharmacological and behavioral treatments that modulate circadian phase, amplitude, and/or robustness of the central circadian clock.</p><p><strong>Summary: </strong>Commercialization of these emerging tools will require overcoming barriers, such as additional testing to confirm the underlying pathology and mechanism of action of potential treatments. Clinicians and scientists are also called to survey adjacent fields and adopt existing diagnostic tools that may offer diagnostic clarity in CRSWDs. Lastly, we must continue to advocate for medical insurance coverage of current and future tools and technologies to improve patient care.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 1","pages":"8"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjana Agarwal, Paige Monsod, Yoon-Sik Cho, Sharon MacRae, Justyna S Swierz, William J Healy, Younghoon Kwon, Xiaoyue Liu, Yeilim Cho
{"title":"Racial Disparity in Obstructive Sleep Apnea Care and its Impact on Cardiovascular Health.","authors":"Sanjana Agarwal, Paige Monsod, Yoon-Sik Cho, Sharon MacRae, Justyna S Swierz, William J Healy, Younghoon Kwon, Xiaoyue Liu, Yeilim Cho","doi":"10.1007/s40675-024-00308-6","DOIUrl":"10.1007/s40675-024-00308-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Racial disparities in sleep health as well as the diagnosis and treatment of sleep disorders have emerged as a key driver of cardiovascular outcomes. Obstructive sleep apnea (OSA), is characterized by repeated airway obstructions during sleep and is associated with an increased risk of cardiovascular disease. While racial and ethnic minorities have disproportionately high OSA prevalence rates, diagnosis rates remain low. One explanation behind this phenomenon are structural environmental and lifestyle barriers that prevent access to OSA care. Additionally, there remains significantly limited understanding of OSA and its causes and symptoms within communities.</p><p><strong>Recent findings: </strong>In general, minorities have poorer sleep health due to systemic and environmental racism, which also causes an increased in conditions such as obesity that increases OSA risk. Disparities also persist within various types of OSA treatment. The most common form of treatment, continuous positive airway pressure (CPAP) has lower adherence among African Americans, as well as those living in areas with low socioeconomic status (SES), primarily minorities. There have been a small number of studies that have shown some initial success of educational campaigns about OSA within minority communities in increasing screenings and diagnoses. Peer based education has been an effective technique, and there is a need for such programs to be expanded.</p><p><strong>Summary: </strong>Disparities persist, with minority groups having worse sleep health and lower rates of adherence to OSA treatment. Some grassroots, peer-led educational campaigns show promise in increasing adherence. In light of these disparities, there remains a need for the field of sleep medicine to continue addressing the systemic barriers that hinder the timely evaluation and treatment in racial minorities.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"10 4","pages":"414-418"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stuti J. Jaiswal, Jeff B. Pawelek, Shiri Warshawsky, Giorgio Quer, Megan Trieu, Jay A. Pandit, Robert L. Owens
{"title":"Using New Technologies and Wearables for Characterizing Sleep in Population-based Studies","authors":"Stuti J. Jaiswal, Jeff B. Pawelek, Shiri Warshawsky, Giorgio Quer, Megan Trieu, Jay A. Pandit, Robert L. Owens","doi":"10.1007/s40675-023-00272-7","DOIUrl":"https://doi.org/10.1007/s40675-023-00272-7","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"10 3","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139124817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Barriers in Access to and Delivery of Behavioral Sleep Treatments","authors":"Sydneyjane Roberts, C. Ulmer","doi":"10.1007/s40675-023-00270-9","DOIUrl":"https://doi.org/10.1007/s40675-023-00270-9","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"11 20","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expanding Access to CBT-I for Older Adults: Review and Expansion of Recent Recommendations","authors":"Jaime M. Hughes","doi":"10.1007/s40675-023-00271-8","DOIUrl":"https://doi.org/10.1007/s40675-023-00271-8","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"95 24","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138954170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Habibolah Khazaie, Saeid Komasi, Reena Mehra, Sepideh Khazaie, A. Alipourian, Vijay Nambi, Amir Sharafkhaneh
{"title":"Insomnia and Incidence of Heart Failure in a Sample of Half a Million People: a Meta-analytic Review and Meta-regression of Prospective Studies","authors":"Habibolah Khazaie, Saeid Komasi, Reena Mehra, Sepideh Khazaie, A. Alipourian, Vijay Nambi, Amir Sharafkhaneh","doi":"10.1007/s40675-023-00269-2","DOIUrl":"https://doi.org/10.1007/s40675-023-00269-2","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"25 1","pages":"281-295"},"PeriodicalIF":1.8,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139238683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina S. McCrae, Ashley F. Curtis, Melanie A. Stearns, Jason G. Craggs
{"title":"Fibromyalgia and the Brain: What’s Sleep got to do with it?","authors":"Christina S. McCrae, Ashley F. Curtis, Melanie A. Stearns, Jason G. Craggs","doi":"10.1007/s40675-023-00268-3","DOIUrl":"https://doi.org/10.1007/s40675-023-00268-3","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":" 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135241719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chenlu Gao, Shahab Haghayegh, Max Wagner, Ruixue Cai, Kun Hu, Lei Gao, Peng Li
{"title":"Approaches for Assessing Circadian Rest-Activity Patterns Using Actigraphy in Cohort and Population-Based Studies","authors":"Chenlu Gao, Shahab Haghayegh, Max Wagner, Ruixue Cai, Kun Hu, Lei Gao, Peng Li","doi":"10.1007/s40675-023-00267-4","DOIUrl":"https://doi.org/10.1007/s40675-023-00267-4","url":null,"abstract":"Abstract Purpose of Review To review methods for analyzing circadian rest-activity patterns using actigraphy and to discuss their applications in large cohort and population-based studies. Recent Findings We reviewed several widely used approaches, including parametric analysis (i.e., cosinor model and wavelet analysis), nonparametric analysis, data adaptive approach (i.e., empirical mode decomposition), and nonlinear dynamical approach (i.e., fractal analysis). We delved into the specifics of each approach and highlighted their advantages and disadvantages. Summary Various approaches have been developed to study circadian rest-activity rhythms using actigraphy. Features extracted from these approaches have been associated with population health outcomes. Limitations exist in prior research, including inconsistencies due to various available analytical approaches and lack of studies translating findings to the context of the circadian system. Potential future steps are proposed. The review ends with an introduction to an open-source software application— ezActi2 —developed to facilitate scalable applications in analyzing circadian rest-activity rhythms.","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke J. Klugherz, Bhanu Prakash Kolla, Meghna P. Mansukhani
{"title":"Pharmacological Treatments for Insomnia","authors":"Luke J. Klugherz, Bhanu Prakash Kolla, Meghna P. Mansukhani","doi":"10.1007/s40675-023-00265-6","DOIUrl":"https://doi.org/10.1007/s40675-023-00265-6","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135878592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationships Between Sleep Disorders, Burnout, Stress and Coping Strategies of Health Professionals During the COVID-19 Pandemic: a Literature Review","authors":"C. Kwee, L. M. Dos Santos","doi":"10.1007/s40675-023-00266-5","DOIUrl":"https://doi.org/10.1007/s40675-023-00266-5","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49432087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}