Daytime Napping in Adults: Benefits or Risks? Insights from Mendelian Randomization Studies.

IF 1.5 Q4 CLINICAL NEUROLOGY

Current Sleep Medicine Reports Pub Date : 2025-01-01 Epub Date: 2025-04-26 DOI:10.1007/s40675-025-00333-z

Aarohi Gupta, Hassan S Dashti

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引用次数: 0

Abstract

Purpose of review: Daytime napping, a brief sleep episode during the day, has mixed health effects. This review explores the relationship between daytime napping frequency and health outcomes by synthesizing results from published Mendelian randomization (MR) studies, which help mitigate confounding and reverse causality commonly observed in traditional epidemiological research.

Recent findings: A total of 35 studies spanning seven major disease categories were identified, with cardiovascular, neurological, and metabolic outcomes being the most frequently investigated in MR. Of the 89 tested outcomes, 36% of studies suggested increased disease risk with more frequent daytime napping, 54% reported no associations, and 10% suggested decreased disease risk with more frequent daytime napping. Not all MR findings align with existing epidemiological research.

Summary: The current evidence from MR does not provide a definitive conclusion regarding the health effects of daytime napping. Future research should consider additional dimensions of napping beyond frequency and integrate both genetic and non-genetic approaches in diverse populations.

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成年人白天午睡：益处还是风险？孟德尔随机化研究的启示。

综述目的：白天小睡，即白天短暂的睡眠，对健康有多种影响。本综述通过综合已发表的孟德尔随机化（MR）研究的结果，探讨了白天小睡频率与健康结果之间的关系，这有助于减轻传统流行病学研究中常见的混淆和反向因果关系。最近的发现：共有35项研究跨越7个主要疾病类别，心血管、神经系统和代谢结果是mr中最常见的研究结果。在89项测试结果中，36%的研究表明白天频繁小睡会增加疾病风险，54%的研究报告没有关联，10%的研究表明白天频繁小睡会降低疾病风险。并非所有磁共振结果都与现有的流行病学研究相符。总结：目前来自核磁共振的证据并没有提供关于白天小睡对健康影响的明确结论。未来的研究应考虑频率以外的其他方面，并在不同人群中整合遗传和非遗传方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Sleep Medicine Reports Medicine-Pulmonary and Respiratory Medicine

CiteScore

2.50

自引率

5.60%

发文量

期刊介绍： Current Sleep Medicine Reports aims to review the most important, recently published articles in the field of sleep medicine. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of sleep conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as insomnia, narcolepsy, sleep apnea, circadian rhythm disorders, and parasomnias. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.