Medeniyet medical journal最新文献_第5页

Interatrial Block and Electrocardiographic Markers of Repolarization in Patients Hospitalized with COVID-19: Classical and Bayesian Analysis COVID-19住院患者房间传导阻滞和复极心电图标志物:经典和贝叶斯分析

Medeniyet medical journal Pub Date : 2023-10-09 DOI: 10.4274/mmj.galenos.2023.87400

Rengin CETIN GUVENC, Ali Kaan GUREN, Busra ENGUR, Selin CELİK, Refik DEMIRTUNC

引用次数: 0

Non-invasive Evaluation of Electromechanical Transmission in Patients with Hypertensive Response to Exercise Stress Test. 运动应激测试对高血压患者机电传导反应的无创评估。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.42027

Ahmet Ferhat Kaya, Mehmet Hasan Ozdil, Cemalettin Yilmaz, Raif Kilic, Mehmet Ozbek, Hasan Kaya

{"title":"Non-invasive Evaluation of Electromechanical Transmission in Patients with Hypertensive Response to Exercise Stress Test.","authors":"Ahmet Ferhat Kaya, Mehmet Hasan Ozdil, Cemalettin Yilmaz, Raif Kilic, Mehmet Ozbek, Hasan Kaya","doi":"10.4274/MMJ.galenos.2023.42027","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.42027","url":null,"abstract":"Objective: Excessive hypertensive response to exercise testing is associated with adverse cardiovascular events such as left ventricular hypertrophy and atrial fibrillation (AF). In this study, we examined the relationship between electromechanical delay and excessive hypertensive response to exercise testing.Methods: Twenty-five people who had a hypertensive response to the exercise stress test and 28 people who were similar in age and gender with a normal blood pressure response in the exercise stress test as the control group were included in the study.Results: There was no statistical difference between the study groups in blood pressure holter values, conventional echocardiography findings, and exercise stress test findings. Lateral PA-TDI time (the time from the beginning of the P wave measured by tissue Doppler imaging to the beginning of the A' wave), left atrial electromechanical delay, and interatrial electromechanical delay were observed to be significantly longer in the hypertensive response group to exercise stress test compared with the control group (74.0±6.3 vs. 68.8±5.7, p=0.003; 24.7±7.0 vs. 19.6±7.1, p=0.013; 36.8±8.5 vs. 30.6±6.6, p=0.003, respectively).Conclusions: Early detection of electromechanical delay non-invasively may be useful in this patient group in predicting the development of new AF risk.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/4a/medj-38-180.PMC10542984.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Antibacterial Effect of Tinospora Cordifolia (Guduchi) and Its Role in Combating Antimicrobial Resistance. 卷叶Tinospora Cordifolia（Guduchi）的抗菌作用及其在对抗耐药性中的作用。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.84579

Kavitha Ezhilarasu, Anand Kasiranjan, Shanmuga Priya, Anand Kamaraj

{"title":"The Antibacterial Effect of Tinospora Cordifolia (Guduchi) and Its Role in Combating Antimicrobial Resistance.","authors":"Kavitha Ezhilarasu, Anand Kasiranjan, Shanmuga Priya, Anand Kamaraj","doi":"10.4274/MMJ.galenos.2023.84579","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.84579","url":null,"abstract":"Objective: Tinospora cordifolia, often known as \"Guduchi,\" has a variety of medicinal characteristics, including those that are anti-diabetic, ant-iinflammatory, anti-periodic, anti-arthritic, anti-oxidant, anti-allergic, and anti-stress. Drug development projects face significant obstacles because of the rapid rise in antimicrobial drug resistance in the world healthcare system and the introduction of multidrug-resistant (MDR) strains. In order to combat the MDR infections isolated from patients' bodies, the current study was conducted to evaluate and investigate the antibacterial capabilities of Tinospora cordifolia.Methods: Using the agar well diffusion method, Tinospora cordifolia extracts (aqueous, chloroform, and ethanol) were tested for their antibacterial effectiveness against 30 MDR pathogens, and the 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay was used to determine the minimal inhibitory concentration. To determine whether there were any medicinally useful and significant bioactive ingredients in the plant extract, phytochemical analysis was performed.Results: In comparison to the aqueous extract which had little effect, the antibacterial activity of ethanol and chloroform extracts exhibited a potential antimicrobial effect against most of the tested bacterial isolates. Phytochemical analysis of Tinospora cordifolia extract showed alkaloids, carbohydrates, phytosterols, saponins, tannins, proteins, flavonoids, and terpenoids.Conclusions: Our findings show that Tinospora cordifolia plays a potential role in combating the antimicrobial resistance of clinical isolates.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/51/medj-38-149.PMC10542978.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41153167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors in Vaccine Refusal by Patients Applying for COVID-19 PCR Test. 申请新冠肺炎PCR检测的患者拒绝接种疫苗的因素。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.43959

Ferhat Arslan, Behcet Al, Gorkem Alper Solakoglu, Omer Faruk Gulsoy, Cagatay Nuhoglu, Sema Ayten

{"title":"Factors in Vaccine Refusal by Patients Applying for COVID-19 PCR Test.","authors":"Ferhat Arslan, Behcet Al, Gorkem Alper Solakoglu, Omer Faruk Gulsoy, Cagatay Nuhoglu, Sema Ayten","doi":"10.4274/MMJ.galenos.2023.43959","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.43959","url":null,"abstract":"Objective: This study was designed to determine the reasons for vaccine rejection in patients who applied for the coronavirus disease-2019 (COVID-19) polymerase chain reaction (PCR) test but did not receive the vaccine.Methods: The study was conducted prospectively in the emergency department of a tertiary hospital between 31.01.2022 and 31.05.2022. 1000 patients who applied for the COVID-19 PCR test and refused to be vaccinated were included. The COVID-19 status of the participants, reasons for their application, number of PCR tests, methods of obtaining information about the vaccine, and reasons for the rejection of the vaccine were questioned.Results: 54.6% of the participants were male and 45.4% were female. 60.7% of the patients applied for testing due to symptoms, 25.4% due to contact with people with symptoms, and 23.9% due to travel. 43.3% of the cases had COVID-19 infection; 53.6% of them had tested an average of 2-5 times in the last year. Most of the information about the vaccine was taken from social media, television, medical publications, and people around, respectively. Of the participants, 62.0% believed that COVID-19 vaccines had side effects, 47.3% believed that it had no protection, and 30.9% believed that there was not enough study on the subject. As the age grew, the rate of learning information from social media increased.Conclusions: The most common reasons for COVID-19 vaccine rejection were vaccine side effects, doubtful vaccine protection, and concerns about the lack of sufficient studies on the vaccine. The higher the education level, the higher the vaccine rejection rate.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/f4/medj-38-193.PMC10542973.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clarifications and Corrections Regarding 'Variations in Superficial Palmar Arch: Case Series with Clinico-anatomical Perspective'. 关于“掌浅弓变异：临床解剖学角度的病例系列”的澄清和纠正。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.25936

Ekrem Solmaz

引用次数: 1

Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in the Patients with Euthyroid Hashimoto's Thyroiditis. 甲状腺功能正常的桥本甲状腺炎患者的中性粒细胞与淋巴细胞比率和血小板与淋巴细胞比率。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.41882

Hacer Nur Resber, Mumtaz Takir, Cundullah Torun

{"title":"Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in the Patients with Euthyroid Hashimoto's Thyroiditis.","authors":"Hacer Nur Resber, Mumtaz Takir, Cundullah Torun","doi":"10.4274/MMJ.galenos.2023.41882","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.41882","url":null,"abstract":"Objective: This study aimed to compare the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values in patients with euthyroid Hashimoto's thyroiditis (HT) with healthy control subjects.Methods: This was a single-center, retrospective, cross-sectional study conducted on obese patients aged 18 years and over. The medical records of patients who presented with complaints of being overweight at the obesity clinic between April 2017 and May 2019 were examined. Patients and healthy individuals were included in the study consecutively until the sample sizes reached saturation. Patients with diabetes, cardiovascular disease, chronic inflammatory disease, and malignancy were excluded from the study. The patients' anthropometric measurements, smoking status, blood examination, and thyroid ultrasounds were evaluated. The difference in means between the groups was calculated using the Mann-Whitney U test.Results: The study included 179 participants, consisting of 93 patients and 86 healthy controls. The mean age was 46.6±14.1 years, with most females (91.6%). Although the NLR and PLR values in patients were higher than those in the control group, the difference did not reach statistical significance (p=0.427 and p=0.089, respectively). Furthermore, no significant difference was observed in NLR (p=0.191) and PLR (p=0.668) values between levothyroxine-treated and untreated patients. Correlation analysis revealed weak positive associations between C-reactive protein and thyroid peroxidase antibodies (p<0.05), neutrophils (p<0.01), platelets (p<0.01), and NLR (p<0.05).Conclusions: The findings of this study suggest that NLR and PLR may not serve as effective indicators of systemic inflammation in patients with euthyroid HT, nor do they adequately assess the impact of levothyroxine usage on systemic inflammation.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/42/medj-38-204.PMC10542979.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Thyroid Hormone Levels on Patent Ductus Arteriosus Closure in Newborns. 甲状腺激素水平对新生儿动脉导管未闭的影响。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.25853

Basak Kaya, Hasan Akduman, Dilek Dilli, Semra Cetinkaya, Ahmet Oktem, Utku Arman Orun, Mehmet Tasar, Aysegul Zenciroglu

{"title":"The Effects of Thyroid Hormone Levels on Patent Ductus Arteriosus Closure in Newborns.","authors":"Basak Kaya, Hasan Akduman, Dilek Dilli, Semra Cetinkaya, Ahmet Oktem, Utku Arman Orun, Mehmet Tasar, Aysegul Zenciroglu","doi":"10.4274/MMJ.galenos.2023.25853","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.25853","url":null,"abstract":"Objective: Although the role of thyroid hormones in functional and anatomical closure of patent ductus arteriosus (PDA) is well known, their effects on the medical or surgical closure of PDA in newborns remain unclear. This study aimed to assess the correlation between thyroid function tests and PDA closure through medical or surgical interventions in newborns.Methods: This retrospective study was conducted on 65 newborns diagnosed with hemodynamically significant PDA (hs-PDA), with a premature rate of 81.5% (n=53). The subjects were divided into two groups according to the nature of the ductal closure as medically responsive \"MR-PDA\" or surgically treated \"ST-PDA\". The groups were compared in terms of thyroid hormone levels and other clinical parameters.Results: Thirty-three (51%) of all 65 patients had PDA and responded to medical treatment. Gestational week, birth weight, and mode of delivery were similar between the medical and surgical treatment groups (p>0.05). Free thyroxine levels were significantly lower in the MR-PDA group than in the ST-PDA group (p=0.01).Conclusions: Because hs-PDA is associated with increased morbidity and mortality in the neonatal period, especially in premature infants, we hypothesize that thyroid hormone levels may play a role in the closure of hs-PDA.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/60/medj-38-187.PMC10542982.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center. 三级中心的巨细胞病毒产前常规筛查结果。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.84042

Duygu Tugrul Ersak, Izzet Ozgurluk, Ayse Gulcin Bastemur, Esra Gulen Yildiz, Selcan Sinaci, Ezgi Turgut, Ozgur Kara, Atakan Tanacan, Dilek Sahin

{"title":"Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center.","authors":"Duygu Tugrul Ersak, Izzet Ozgurluk, Ayse Gulcin Bastemur, Esra Gulen Yildiz, Selcan Sinaci, Ezgi Turgut, Ozgur Kara, Atakan Tanacan, Dilek Sahin","doi":"10.4274/MMJ.galenos.2023.84042","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.84042","url":null,"abstract":"Objective: Cytomegalovirus (CMV) is the most common viral infection. In this study, we discussed the results of pregnant women who underwent antenatal CMV screening in a tertiary center and the value of CMV antenatal screening.Methods: For this retrospective study, the data of pregnant patients with antenatal CMV screening test results between 2019 and 2022 were obtained from hospital records. CMV immunoglobulin M (IgM), CMV IgG, anti-IgG avidity test results, amniocentesis, CMV polymerase chain reaction (PCR), and the outcome of the babies were recorded.Results: A total of 31,912 CMV IgM and 26,969 CMV IgG tests were performed. CMV IgG seropositivity was observed in 78.99% of pregnant women, and 0.09% of the pregnant women were confirmed to have a positive CMV IgM test result. Pregnant women with positive IgM accompanying low avidity were referred to perinatology clinics for detailed ultrasonography and amniocentesis. Only 3 of the 44 pregnant women who underwent amniocentesis were confirmed to have positive CMV PCR testing.Conclusions: CMV screening should be preserved for pregnant women with ultrasonographic findings at high risk of congenital CMV infection.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/88/medj-38-167.PMC10542985.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41138917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Solmaz's Letter to the Editor about our article titled "Variations in Superficial Palmar Arch: Case Series with Clinico-anatomical Perspective". 对Solmaz给编辑的关于我们题为“掌浅弓变异：临床解剖学视角的病例系列”的文章的回复。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.40327

Dibakar Borthakur, Rajesh Kumar, Seema Singh

引用次数: 0

Investigation of Morphological and Biomechanical Properties of the Scapula for Shoulder Joint. 肩关节肩胛骨的形态和生物力学特性研究。

Medeniyet medical journal Pub Date : 2023-09-28 DOI: 10.4274/MMJ.galenos.2023.15483

Nilgun Tuncel Cini, Nazan Guner Sak, Serdar Babacan, Ilknur Ari

{"title":"Investigation of Morphological and Biomechanical Properties of the Scapula for Shoulder Joint.","authors":"Nilgun Tuncel Cini, Nazan Guner Sak, Serdar Babacan, Ilknur Ari","doi":"10.4274/MMJ.galenos.2023.15483","DOIUrl":"https://doi.org/10.4274/MMJ.galenos.2023.15483","url":null,"abstract":"Objective: The glenopolar angle is a helpful criterion for recommending operative treatment. This study aims to determine the morphometric features of the scapula and provide essential information that supplies scapular biomechanics to produce a formula.Methods: The study was carried out on 34 dry scapulae in the laboratory of the Anatomy Department of the Faculty of Medicine, Bursa Uludag University. We used calipers for the linear measurements and the ImageJ program for the area and angle parameters. A total of 23 parameters were evaluated in the study. Statistical analyzes were performed using SPSS 22.0 software.Results: According to the results of the correlation analysis, the highest correlation value of (R=0.957) was found to be the distance between the superior angle (angulus superior)-top of the glenoid plane and the inferior angle (angulus inferior)-the top of the glenoid plane. To estimate the glenopolar angle, we applied linear regression analysis and developed the following formula: Glenopolar angle =115.589 - (6.401 x the distance between the coracoid process and the top of the glenoid cavity) - (0.368 x angle between the glenoid plane and the lateral edge of the scapula extending towards the endpoint of the glenoid plane) (Adjusted R2=0.667).Conclusions: Glenopolar angle can provide information about the fracture risk of the glenoid cavity and allows orthopedic surgeons to make quick decisions about the risk in the region. We believe that the study will provide a different perspective on designing different products in industrial designs for shoulder joints, especially in implantations.","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/b4/medj-38-159.PMC10542975.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0