Journal of Ophthalmology Research Reviews & Reports最新文献

{"title":"Central Serous Chorioretinopathy: A Review of Pathogenesis, Risk Factors, Diagnostic Methods and the Current Treatments","authors":"A. K. Kocak altintas","doi":"10.47363/jorrr/2021(2)114","DOIUrl":"https://doi.org/10.47363/jorrr/2021(2)114","url":null,"abstract":"Central serous chorioretinopathy (CSCR) is characterized by serous detachment of the neurosensory layer at the macula. It has a relatively high recurrence rate and mainly affecting middle-aged males. The etiology and pathogenesis of the disease still remain ambiguous. But choroidal changes which increase choroidal vascular permeability are the basic pathology of CSCR. Different diagnostic methods such as FAF, FFA, OCT, OCTA, ICG could be used to detect its biomarkers such as choroidal thickness, choroidal vascularity index, hyperreflective dots for exact diagnosis and treatment response. Acute CSCR generally self-limited, but in recurrent or chronic forms may cause permanent visual loss due to progressive and irreversible damage in the photoreceptor layer of retinal pigment epithelium atrophy. Several treatment alternatives have been reported, such as PDT, intravitreal Anti-VEGF, TTT, Laser, Mineralocorticoid receptor antagonist for chronic and recurrent CSCR.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"600 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116072936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic Retenopathy Management - A Case Study","authors":"Gouri Sakre","doi":"10.47363/jorrr/2021(2)113","DOIUrl":"https://doi.org/10.47363/jorrr/2021(2)113","url":null,"abstract":"Diabetic retinopathy is a complication of diabetes, caused by high blood sugar levels damaging Retina. It usually takes several years for diabetic retinopathy to reach a stage where it could threaten the sight, if left undiagnosed and untreated. Starting with only a mild vision problem, retinopathy usually appears five years after a type 1 diabetes diagnosis. But it may already be present when type 2 diabetes is diagnosed. We present one such case in a lady of 38 years old, tailor by profession, diagnosed as Type 2 diabetes since 2019, suspected to have had proliferative diabetic retinopathy in January 2020, reported at a Medical College Hospital on 15th December 2020 with periorbital headache for fifteen days. Fundal examination revealed hard exudates and Neo vascularization in both eyes. She was advised Photocoagulation but after her blood sugar was controlled. In the meantime, she was advised to use Nepafenac eye suspension four times daily for pain and redness of the right eye. Investigations had revealed her RBS was 392mg/dl, for which a general physician (internal medicine) was consulted who put her Tab. Metformin 500mg 1-1-1 B/F, Tab. Teneligliptin 20mg 0-1-0 A/F. Unfortunately, 2 months of follow up and diabetes management did not allow her to be taken up for photocoagulation. The institution was firm on their decision to plan her laser photocoagulation for both eyes only when the blood sugar levels come to a range of 140 to 160mg/dl. On 26th March 2021, she was rushed to the Medical College hospital as she complained of loss of vision in the Right eye. The fundus examination revealed multiple dot and blot hemorrhages in both eyes, bleed in oculus dexter and oculus sinister, hard exudates in the right eye that needed Vitreoretinal surgery. Since the Medical College Hospital did not have the Vitreoretinal surgery facility, she was taken to a private dedicated eye hospital, where she underwent laser photocoagulation of left eye on 12/04/21 followed by Vitrectomy of right eye for proliferative diabetic retinopathy on 24th April 2021. There were no postoperative hemorrhages until three days or any other complications after surgery. Now she can recognize some shapes with her right eye by closing left eye.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"424 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117268411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multiple Sclerosis Mimiker with Good Recovery following Specific Therapy: Susac Syndrome","authors":"Torri Clerici Valentina, Bianchi-Marzoli Stefania","doi":"10.47363/jorrr/2021(2)112","DOIUrl":"https://doi.org/10.47363/jorrr/2021(2)112","url":null,"abstract":"Susac Syndrome (SuS) is a rare disease, characterized by an autoimmune endothelopathy, that involves brain, retina and inner ear. We describe a case of a young woman affected by inner ear-predominant SuS, initially suspected for demyelinating disease, with delayed diagnosis and irreversible hearing ischemic damage, but good prognosis, treated according to current recommendations","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133969549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital T-Cell Lymphoma – A Challenging Case","authors":"P. Baptista, C. Castro, L. Regadas","doi":"10.47363/JGRRR/2021(2)109","DOIUrl":"https://doi.org/10.47363/JGRRR/2021(2)109","url":null,"abstract":"","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117151602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Endophthalmitis, Then and Now","authors":"S. Dhanireddy, Philip Kurochkin, Neelima Dosakayala","doi":"10.47363/JORRR/2020(1)101","DOIUrl":"https://doi.org/10.47363/JORRR/2020(1)101","url":null,"abstract":"Purpose: Report the frequency of differing etiologies of endophthalmitis at the Upstate Medical University, and compare these results to previously reported data. Methods: A retrospective study was conducted based on the medical records of all patients diagnosed with endophthalmitis at the Upstate Medical University in Syracuse, New York between January 2014 to December 2019. Variables recorded included source of infection, microbial profiles, comorbidities, visual acuity and survival. Results: The study identified 62 patients who were diagnosed with endophthalmitis at the Upstate Medical University from January 2014 to December 2019. The most common etiology was endogenous endophthalmitis with 40 cases (64.5%), of these patients, 13 (32.5%) were culture positive. The remaining 22 cases (35.5%) were due to exogenous endophthalmitis. The mean age of patients with endogenous endophthalmitis was 51.4 years with 65.0% as male. The mean age of patients with exogenous endophthalmitis was 59.5 years with 59.1% as male. The most common identifiable risk factor associated with endogenous endophthalmitis was a history of intravenous drug use seen in 47.5%. Conclusion: Endogenous source was established as the most common etiology in patients diagnosed with endophthalmitis. These results, however, do not parallel with any of the previously reported data where endogenous etiology was identified as one of least common causes. The significance of demonstrating this increase in incidence of endogenous endophthalmitis is to illustrate a shift in paradigm and create awareness among ophthalmologists to avoid overlooking a possible life-threatening condition.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115763488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Taurine Preserve Visual Acuity in a Patient with Pathologic Myopia?","authors":"Lina R Paez, Norma E Ávila Portillo","doi":"10.47363/JORRR/2020(1)106","DOIUrl":"https://doi.org/10.47363/JORRR/2020(1)106","url":null,"abstract":"Taurine, a semi-essential amino sulfonic acid, is present in high amounts in the retina. It has anti-inflammatory, antioxidant, and neuromodulatory properties which have shown to be beneficial for specific neurodegenerative conditions [1]. However, its effects on high myopia or its complications are unknown. We report the case of a 60-year-old woman with pathological myopia, who 7 years ago, presented a best corrected visual acuity (BCVA) of 20/200 right eye (OD) and 20/70 left eye (OS), and was diagnosed with a choroidal neovascular membrane (CNV) OS. She initiated taurine supplementation (1.5 g/ daily for 14 days) and improved to a BCVA of 20/100 OD. She continued taking 500 mg/daily. Subsequent events included 4 injections of Aflibercept OS, cataract surgery in both eyes (AO), and peripheral retinal photocoagulation in AO. This last treatment induced a severe inflammation and loss of visual acuity OS. She was treated with corticosteroids, but after two weeks due to lack of improvement, the taurine dose was increased to 1 g/day. Three weeks after, her BCVA went from counting fingers to 20/60 OS, and her inflammation was controlled. After 7 years of continuous taurine intake, her CNV OS has remained inactive, her BCVA was stable and even improved in the last year from 20/45 OD and 20/80 OS to 20/25 OD and 20/60 OS, respectively. At the same time, her migraines decreased in intensity and frequency. This case report brings a new light towards the potential use of taurine supplementation in high myopia, retinal degeneration, and pathologic myopia.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129919103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Definition of Different Treatment Response Types In Neovascular Age-Related Macular Degeneration","authors":"A. Altıntaş","doi":"10.47363/JORRR/2020(1)102","DOIUrl":"https://doi.org/10.47363/JORRR/2020(1)102","url":null,"abstract":"Age-related macular degeneration (AMD) is a common, degenerative disease of the retina presented as neovascular AMD (n-AMD) or non‐neovascular AMD. Several factors risk factors having been found associated with unresponsive to treatment and progression macular scar form, including subtype of the choroidal neovascular membrane (CNM), presence of subretinal drusenoid deposits, Pigment epithelial detachment (PED), decreased central choroidal thickness, preexisting Macular atopy (MA) in the fellow eye. There is no exact consensus about the term described the status of poor or non- response to any treatment regime. In this article definition of different therapeutic responses such as resistance, refractory, recurrence of anti-vascular endothelial growth factors (AntiVEGF), and its relation to retinal features are discussed.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131886473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral Ulcerative Keratitis: A Novel Presentation","authors":"K. Stonecipher, North Church Street Suite Greensboro Nc Usa Physicians Protocol, Casey Komm, M. Goyal","doi":"10.47363/JORRR/2020(1)103","DOIUrl":"https://doi.org/10.47363/JORRR/2020(1)103","url":null,"abstract":"Volume 1(1): 1-2 Presentation A 46 year-old man presented to our center with a one week history of foreign body sensation in his left eye and blur. The patient reported no trauma and no inciting event. The patient indicated he was using Besivance eye drops every hour in the left eye for which he was prescribed by his outside provider four days earlier. The patient’s uncorrected visual acuity was 20/20 in the right eye and 20/200 in his left, with no improvement with pinhole. The patient’s pupillary exam was normal and IOP was 7 in both eyes. The patient’s exam was notable for +1 left upper eyelid edema, +2 conjunctival injection, most significantly adjacent to the 10 o’clock position where there was a peripheral 2.5mm circumferential corneal ulcer.","PeriodicalId":373984,"journal":{"name":"Journal of Ophthalmology Research Reviews & Reports","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124926057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}