Journal of Rangpur Medical College最新文献

{"title":"Pattern of Breast Cancer in Women at Child-bearing Age, its Risk Factors and Clinicopathological Evaluation in Tertiary Level Hospital","authors":"Md Rasedul Haque, Md Amzad Hossain","doi":"10.3329/jrpmc.v9i1.72708","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72708","url":null,"abstract":"Background: Carcinoma breast is the leading cancer in female in Bangladesh, increasing significantly due to urbanization and adoption of western life style. Objective: This study aimed to systematically understand the pattern of breast cancer, its risk factors and clinicopathological evaluation in women at their childbearing age. Methods: A cross sectional observational study, data was collected from 50 patients of histopathologically confirmed breast cancer in the department of Surgery, Combined Military Hospital, Dhaka from 2022 to 2023. Results: The majority of the cases were 41-45(42%) years age with mean presentation was 43.55 (SD-/+9.63) years. Invasive ductal carcinoma was the most common subtype 86%, followed by ductal carcinoma in situ (8%). Of the cases 2% were nullipara and 46% had two children. Median age of at 1st birth was 21 years. A significant proportion (16%) had family history of breast cancer. 98% patients gave history of breast feeding. Conclusions: Breast cancer is increasingly occurring in younger age groups in Bangladesh, results suggested a mixture of different factors in women like age of menarche, age of first child birth, parity, history of breast feeding and family history poses higher risk for breast cancer. \u0000J Rang Med Col. March 2024; Vol. 9, No. 1:16-21","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy with Non-cirrhotic Portal Hypertension: A Case Report","authors":"Iffat Ara, Safura Khatun","doi":"10.3329/jrpmc.v9i1.72792","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72792","url":null,"abstract":"Pregnancy with non cirrhotic portal hypertension is an uncommon condition. Due to physiological changes in pregnancy, the patients with portal hypertension may exaggerate and produce life threatening complicationslike variceal haemorrhage and increased incidents of adverse maternal and fetal outcomes. Pregnancy also predisposes the patient to develop hepatic decompensation. So, management of such cases requires a multi-disciplinary approach. In this case report,21-year-old primigravida presented with known case of non cirrhotic portal hypertension at her 33 weeks of pregnancy with huge splenomegaly and history of hematemesis.The pregnancy ran uneventfully, and she underwent elective LSCS at 38+ weeks and gave birth of a live female baby, weighing 3kg was delivered. Post operative recovery was uneventful. The patient was discharged on the 4th post operative day. We want to focus upon different aspects of pregnancy with portal hypertensionto prevent complications and manage the case.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 86-88","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"270 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital Acquired Diarrhoea in Children: A Study in a Tertiary Care Hospital in Sylhet","authors":"Tahmina Jahan Chowdhury, Naznin Akther, Jannatul Ferdush Chowdhury, Shaila Begum, Zainab Rahman, Tofayel Ahmed","doi":"10.3329/jrpmc.v9i1.72723","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72723","url":null,"abstract":"Background: Children hospitalized for diseases other than diarrhoea can be infected with an enteric pathogen during their stay at hospital, which may complicate and prolongs the course of illness and hospital stay. Hospital acquired diarrhoea are defined as those occurring more than 72 hours after admission to hospital. Nosocomial diarrhoea second to nosocomial respiratory tract infections in causing morbidity among hospitalized children. Objectives: The study was designed to find the rate of hospital acquired diarrhoea, their risk factors and to observe the clinical features. Method: This cross-sectional observational study was conducted in the inpatient department of Pediatrics in Jalalabad Ragib-Rabeya Medical College, Sylhet over a period of 3 months between July to September 2018. A total number of 274 children aged from 1 month to 5 years were admitted in inpatient department other than diarrhoea were included in the study. During their hospital stay, all patients were followed up daily for development of diarrhoea. Results: Out of 274 children 80 patients developeddiarrhoea 72 hours after admission, the rate of occurrence of hospital acquired diarrhoea was 29.2%. Patients who developed hospital acquired diarrhoea, were initially admitted due to pneumonia accounted for about 65% followed by 12.5% due to malnutrition. Patients aged below two years and staying in hospital for longer duration developed diarrhoea more. Presence of any diarrhoeal patient in a bed close the patient’s bed (p=0.00001), hand washing by mother’s during handling baby (p=0.00001), hand washing by doctors (p=0.00001), and sharing the bathroom with diarrhoeal patient (p=0.000061), were statistically associated with the development of nosocomial diarrhoea. Diarrhoea was mostly watery in nature (80%) having pus (80%) and RBC (100%) on stool microscopy and patients suffered from milder dehydration (80%). Conclusions: Hospital acquired diarrhoea is common in admitted patients, which may complicate the disease course, prolonged the hospital stay.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 65-70","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"239 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Recovery Rate and Early Complications Between Primary Resection and Two-stage Operation in the Treatment of Acute Non- Complicated Sigmoid Volvulus","authors":"M. R. Alam, Koushik Sikder, Md Ferdoush Rayhan, Mohammad Imrul Hasan Chowdhury, Ashrafur Rahman, Md Tarek Hasan, Shovon Sayeed","doi":"10.3329/jrpmc.v9i1.72722","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72722","url":null,"abstract":"Background: This study compares recovery rates and early complications associated with primary resection and a two-stage operation in treating acute sigmoid volvulus, a gastrointestinal emergency requiring prompt intervention. Proper diagnosis and appropriate operative approaches are crucial for lifesaving treatment. Objectives: This study was aim to compair of recovery rate and early complecations between two operative procedures. Methods: The cross-sectional analytical study was conducted from May to October 2015in National Institute Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh, involved 50 patients with acute non-complicated sigmoid volvulus, randomly divided into two groups, with the outcome variable being the only difference between two groups. Results: Two stage operation patients experienced 24% stomal complications, while one stage operation patients did not experience any late complication. The mean time for one stage operation was longer, and one stage operation resulted in 200 ml blood loss compared to 156 ml in two stage operations. Conclusion: In consideration of anastomotic leakage, operative time, operative blood loss post-operative hospital stay, two stage operation was better than primary resection.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 59-64","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"311 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Hypocalcemia and Hypomagnesemia in Autistic Spectrum Disordered Children of Bangladesh","authors":"Shahana Parvin, Shorifa Shahzadi, Shelina Begum, Syeda Nusrat Mahruba","doi":"10.3329/jrpmc.v9i1.72721","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72721","url":null,"abstract":"Background: Autistic spectrum disorder (ASD) in children is commonly associated with mitochondrial dysfunction and mineral deficiency. Studies have highlighted links between Ca2+ and Mg2+ deficiency and neuronal excitability, along with connections between iron deficiency and behavioral abnormalities in individuals with ASD. Objective: This study was aimed to assess the frequency of hypocalcemia and hypomagnesemia in autistic spectrum-disordered children of Bangladesh. Methods: This cross-sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University, Dhaka from March 2014 to January 2015. The study included 100 randomly selected male children, with 50 in a healthy control group (Group A) and 50 diagnosed with autistic spectrum disorder (Group B). Children with ASD were selected from the Parents Forum (DOHS, Mohakhali), while the control group was chosen from schools with typically developing children. Fasting serum levels of various components along with calcium and magnesium were measured, and statistical analysis was conducted using independent sample 't' tests and proportion (Z) tests, with a significance level set at p-value ˂0.05. Results: In this study, out of 50 autistic spectrum disorder cases, the frequencies of hypocalcemia and hypomagnesemia were 74% and 52%, respectively. A comparison with the control group revealed significantly higher frequencies of both hypomagnesemia and hypocalcemia in the ASD group, with p-values <0.001. Conclusions: Among most children with autism spectrum disorder in Bangladesh, hypocalcemia and hypomagnesemia are prevalent. These prevalences are significantly higher than those observed in healthy children.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 55-58","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"307 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Maternal and Neonatal Complications in Women with and without Gestational Diabetes Mellitus","authors":"Tania Akbar, Sheuly Begum, Anuradha Karmaker, Marmarin Hamid, Rokshana Parvin Nupur","doi":"10.3329/jrpmc.v9i1.72710","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72710","url":null,"abstract":"Background: Gestational Diabetes Mellitus (GDM) is a common pregnancy-related metabolic disorder associated with adverse maternal and neonatal outcomes. Gestational Diabetes Mellitus is characterized by glucose intolerance that develops during pregnancy. It affects approximately 7% of all pregnancies and has been linked to an increased risk of maternal and neonatal complications. Objective: The study was aimed to provide a comprehensive comparison of maternal and neonatal complications in women with and without GDM involving a thorough examination of medical records and clinical data to identify patterns and associations between GDM and various complications. Methods: A retrospective cohort study was conducted, including pregnant women with and without GDM who received prenatal care and underwent hospital delivery at the Department of Obstetrics and Gynecology, Enam Medical College and Hospital, Dhaka, Bangladesh from June 2022 to June 2023. Clinical data, including maternal age, gestational age at diagnosis, parity, and antenatal care were collected. Pregnancy outcomes, such as maternal complications, and live birth complications were also assessed. Result: A total of 60 pregnant women were included in the analysis, 30 were diagnosed with GDM and 30 without GDM. Analysis of pregnancy outcomes revealed a higher incidence of cesarean section deliveries in the GDM group (p<.05). Additionally, infants born to mothers with GDM had a higher risk of neonatal complications. Conclusions: Women diagnosed with GDM demonstrated distinct clinical characteristics and experienced a higher incidence of adverse pregnancy outcomes. These findings underscore the importance of effective management and close monitoring of pregnant women with GDM to optimize maternal and neonatal health.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 28-32","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"348 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Laboratory Predictors of Mortality in Pediatric Patients with Severe Dengue at Dhaka Shishu Hospital","authors":"Moshrefa Newaz, Mashhura Huq, Sabrina Akter, Tahera Nasrin, Fahmida Hossain, Afsana Khanom","doi":"10.3329/jrpmc.v9i1.72700","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72700","url":null,"abstract":"Background: Dengue fever, particularly in its severe form, poses a significant health challenge in tropical regions like Bangladesh. Understanding the clinical and laboratory predictors of mortality in pediatric patients with severe dengue is crucial for improving management strategies and patient outcomes. Methods: This cross-sectional analytical study was conducted at the Department of Pediatrics, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh, from January 2019 to December 2020. It included 300 pediatric patients diagnosed with severe dengue. Results: Of the 300 participants, 286 (95.33%) survived, while 14 (4.67%) succumbed to the disease. Major bleeding, refractory shock, a significant rise in hematocrit, signs of pleural effusion, and ascites were significantly associated with mortality. Hematologically, a low platelet count (<15000/mm3) was a strong predictor of mortality. Elevated serum ferritin levels (>500 micrograms/L) were also significantly associated with increased mortality risk. Conclusions: The study highlights major bleeding, refractory shock, significant hemoconcentration, pleural effusion, ascites, low platelet count, and high serum ferritin levels as key predictors of mortality in pediatric patients with severe dengue. These findings underscore the need for comprehensive clinical monitoring and targeted management strategies to improve outcomes in pediatric dengue patients. \u0000J Rang Med Col. March 2024; Vol. 9, No. 1:10-15","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"295 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Pregnancies in Women with Congenital Heart Disease: A Study in a Tertiary Care Hospital in Bangladesh","authors":"Hasina Akhter, Nahid Reaz Shapla, Kamrun Nahar","doi":"10.3329/jrpmc.v9i1.72798","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72798","url":null,"abstract":"Background: Pregnancies in individuals with congenital heart disease (CHD) frequently pose complex challenges. The presence of CHD elevates the risks not only for the expectant mother but also for the well-being of the developing fetus. Additionally, careful monitoring and specialized medical care are crucial throughout the pregnancy to ensure the best possible outcomes for both. Objective: This study was aimed to assess the outcomes of pregnancies in women with congenital heart disease. Methods: This was a cross-sectional observational study that was conducted in the Combined Military Hospital (CMH), Dhaka, Bangladesh from January 2020 to December 2021. A total 30 pregnant women with congenital heart disease were enrolled through purposive sampling. All the demographic and clinical information was recorded. Data were processed, analyzed, and disseminated by using MS Office tools. Results: Among participants, Lower Segment Cesarean Section (LSCS) was the most common delivery (43.3%), followed by vaginal delivery (36.7%). Instrumental delivery, specifically through outlet forceps, was found in 6.7% of cases. Pregnancy termination occurred in 6.7% due to inevitable abortion and 3.3% for medical reasons, resulting in one maternal death (3.3%). Perinatal outcomes included 90% live births and 81.5% with Apgar scores ≥9. Neonatal Intensive Care Unit (NICU) admission was required for 33.3%, with a 3.3% perinatal death rate. Conclusions: In pregnant women with congenital heart diseases, common delivery modes are Lower Segment Cesarean Section (LSCS) and vaginal delivery. Termination and maternal fatality rates are low. Perinatal outcomes are generally positive, with most births resulting in live infants with Apgar scores ≥9 and high newborn survival rates, although some require Neonatal Intensive Care Unit (NICU) admission.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 50-54","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"276 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bruxism in Children","authors":"Obehi O Osadolor, Otakhoigbogie U, A. Osadolor","doi":"10.3329/jrpmc.v9i1.72791","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72791","url":null,"abstract":"Background: Bruxism can occur in children living or residing in slums areas, rural areas, remote and urban communities. The prevalence of bruxism among children varies in the literature. Bruxism is associated with sound during teeth clenching or involuntary teeth grinding, and this can disturb parents, guardian and family members. It can be diagnosed with clinical history, clinical examinationand use of electromyography and polysomnography. Method: An electronic literature search in science direct and goggle was done in December 2023 using the Population, Concept and Context framework. Search terms and keywords were combined by Boolean operators. Two independent investigators screened titles and abstracts of publications on bruxism among children. Original (primary) research articles with accessible full text were included for review, while review articles, systematic reviews, thesis, dissertations and perspectives related to bruxism among children were among articles excluded during screening. Original (primary) research articles related to voluntary tooth clenching,other oral habits and bruxism/tooth grinding among children with special health care needs were also excludedduring screening. Results: Abstract and full texts were screened using inclusion criteria by two independent investigators. The identified study was carried out in Egypt, Ugandaand South Africa respectively. Conclusion: Bruxism can occur among children.Itcan affect the quality of life of childrenwith tooth sensitivity, tooth attrition with wear facets, and psychological concerns.More studies from diverse ethnic population and countriesin Africa countries will fill the gaps in knowledge and add to the existing literature.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 82-85","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"33 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Sociodemographic Status and Physical Functioning of Obese School Going Children- A Cross Sectional Study","authors":"Abm Ariful Islam, Md Abu Zafar Al Murad, F. T. Johora","doi":"10.3329/jrpmc.v9i1.72788","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72788","url":null,"abstract":"Background: Obesity is major non-communicable disease (NCD) all over the world affecting both children & adult. More than 30 million overweight children are living in developing countries & 10 million in developed countries. Childhood obesity leads to a significant reduction in health-related functioning. So, the negative effects of childhood obesity on quality of life (QoL) have to be determined to combat the problem. Objective: To determine the association between sociodemographic status and physical functioning of obese school going children. Methods: This was a cross sectional type of descriptive study conducted at different schools of Rajshahi city from June 2015 to September 2015. Four (4) schools were selected- a) Govt. Laboratory High School, Rajshahi b) Rajshahi Collegiate School c) River view Collectorate School, Rajshahi and d) Rajshahi University School. The study population were 5 to 15 years old obese school children. A total number of 221 children were interviewed. Results: The ages of the respondents were between 4 to 15 years, and the mean age was 7.83±3.058 years. Among the 221 respondents more than half (56.6%) were in 4-7 years of age group, another 24.0% belonged to the age group of 8- 11 years and only 19.5% were 12- 15 years age group. Weight of the respondents was from 20 to 65 kg and mean weight of the respondents was (41.64±10.75). Here, 36.2% weight was from 37-47 kg and 29.0% weight was from 26-36 kg. Another 23.1%, 7.7% and 4.1% weight was from 48-58 kg, 59-69 kg and 15-25 kg respectively. There was no significant relationship with respondent age and sex with physical functioning (p ≥ 0.05). There was a significant relationship with weight and physical functioning (p≤0.05). Conclusions: The sociodemographic status may influence the physical functioning of the obese school going children. Their lifestyle must be modified in this early life otherwise they will be affected by different non communicable disease\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 71-76","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"285 S2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}