Journal of Rangpur Medical College最新文献

{"title":"Vitamin D and it’s Association with FokI VDR Polymorphism in Patients with Asthma-COPD Overlap","authors":"Sharkia Khanam Rosy, Taskina Ali, Subroto Kumar Biswas, Md Asaduzzaman, Md Sarwar Murshed Alam, Md Habibur Rahman, M. Anwar, Md Nuruzzaman","doi":"10.3329/jrpmc.v9i1.72709","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72709","url":null,"abstract":"Background: Asthma-COPD overlap is a new phenotype in respiratory ailments. It has been shown that this group of patients might possess vitamin D3 deficiency. The association of vitamin D receptor (VDR) gene polymorphism with serum vitamin D status in ACO patients has not been investigated yet. Objective: To assess the association of VDR gene polymorphism (FokI) with serum vitamin D status in patients with Asthma-COPD overlap. Methods: This cross-sectional study was carried out in the Department of Physiology of Bangabandhu Sheikh Mujib Medical University, Dhaka, from January 2018 to July 2018 on 23 (twenty-three) patients (aged ≥40 years) with ACO. For comparison, 24 (twenty-four) apparently healthy age, smoking duration and BMI matched subjects were selected. For all participants single nucleotide polymorphism of VDR gene FokI (rs10735810) was done by DNA extraction, polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). Vitamin D3 was measured by using automated analyzer: ARCHITECT Plus ci4100. The results were expressed as mean with standard error (mean±SEM) and frequency distribution. The data were statistically analyzed by Graphpad prism (Version 7) using independent sample ‘t’ test, two sample proportion test, Fisher exact test and ANOVA test. In the interpretation of results, ≤0.05 level of probability (p) was accepted as significant. Results: The mean±SEM of serum 25(OH)D were 16.37±0.78 and 18.46±1.01 ng/ml in control and study groups, respectively. The frequency distribution of FokI genotype was 86.95% (FF), 8.69% (Ff), 4.35% (ff) and 91.66% (FF), 4.17% (Ff), 4.17% (ff) in ACO patients and healthy subjects, respectively. When FoKI VDR SNP was analyzed with serum vitamin D status in patients with ACO, statistically no association was seen. Conclusions: FokI VDR SNP is not associated with serum vitamin D status in patients with ACO.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 22-27","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"286 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E- Health in Bangladesh: Are we Ready for the Commuter?","authors":"Shah Md Sarwer Jahan","doi":"10.3329/jrpmc.v9i1.72698","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72698","url":null,"abstract":"Abstract not available\u0000J Rang Med Col. March 2024; Vol. 9, No. 1:1-2","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"276 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D status in Type 2 Diabetes Mellitus in a Tertiary Level Hospital","authors":"Sharnasree Saha, Anupam Sarker, Progga Sarker, Sajeda Afrin, M. Anwar, Chandra Rani Sarkar","doi":"10.3329/jrpmc.v9i1.72789","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72789","url":null,"abstract":"Background: There is increasing evidence of a relationship between vitamin D status and type 2 diabetes. Diabetes has also been found to be associated with 25(OH)D (vitamin D) deficiency and the role of vitamin D has recently emerged, especially in preventing cardiovascular diseases and cancer. and insulin resistance. Objective: This study aimed to compare vitamin D deficiency between healthy and Type 2 Diabetes Mellitus (T2DM) patients. Methods: This cross-sectional study was conducted from July 2021 to June 2022 in the Department of Physiology, Rangpur Medical College, Rangpur. For this study, a total number of 100 subjects were selected among them 50 non-diabetic healthy subjects were included as control and 50 Type 2 Diabetes Mellitus patients were included as cases. The subjects of control were selected from the surrounding community of Rangpur district and subjects of cases were selected from Diabetic Association and from Outdoor of Endocrinology Department, Rangpur Medical College and Hospital, Rangpur. For statistical analysis, an independent sample t-test was performed by computer-based software SPSS-23.0 version for windows. Results: The mean vitamin D level was lower in the diabetic patients than in non-diabetic participants (14.1±8.3 ng/ml and 37.3±11.3, p<0.001). Conclusions: Early screening for serum vitamin D level is recommended for T2DM patients. Hence, it is crucial to promptly address any deficiencies in vitamin D levels.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 77-81","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"54 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141011648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and Clinical Characteristics of Persons with Epilepsy Attending an Epilepsy Clinic of a Tertiary Hospital in Bangladesh","authors":"Md Ruhul Amin, Md Emdadul Haque, Sukumar Majumder, Md Abu Hanif, Proshanta kumar Pondit, Md Montashim Morshed","doi":"10.3329/jrpmc.v9i1.72720","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72720","url":null,"abstract":"Background: Epilepsy is a common neurological disorder found in all societies. It is seen that the relative frequency of various clinically important characteristics is different in persons with epilepsy (PWE) living in different geographical areas. The purpose of this study was to describe the sociodemographic and clinical characteristics of a cohort of patients with epilepsy from an Epilepsy Clinic of a tertiary hospital in Bangladesh. Methods: This cross-sectional study was conducted in the Department of Neurology at Rangpur Medical College Hospital, Rangpur, Bangladesh, from July 2022 to June 2023. The patients were recruited from the epilepsy clinic. A structured questionnaire was designed to collect relevant information by interviewing the consecutive PWEs. Results: A total of 252 PWEs were recruited, of which 134(53.2%) were male. Most [200(79.4%)] of them were young (age group 0 to 29 years) and had generalized seizures 147(58.3%). The median age of the 1st seizure was 11 years (range 0.5-73.0), and the median duration of epilepsy was 5.0(0-35) years in the present study. EEG, CT scan, and MRI could be done in 200(79.4%), 128(50.8%), and 68(27%, respectively. Among them, 24.2%(61), 10.7%(27), and 11.1%(28) patients had different types of abnormalities on EEG, CT scan, and MRI, respectively. A family history of seizures was present in 20(7.9%) patients. Sixteen patients(6.3%) were not getting any AEDs, 63.1% and 30.6% were on single and multiple AEDs, respectively. Sixty-five (25.8%) patients reported stopping the drug without any medical consultation. Forgetfulness was the most reported (21, 33.8%) reason for stopping drugs, followed by the misconception that the disease was cured (14, 21.5%), lack of time to buy pills (12, 18.5%), and no money to buy (9, 13.8%). Seventy-seven reported having two or more continuous seizures despite taking AEDs regularly. Conclusions: Present study documented some treatment gap and non-adherence to medication in PWE. PWE should be adequately advised about the disease and the effects of drug non-compliance.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 44-49","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"297 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Morbidity and Mortality of Eclampsia at Brahmanbaria Medical College and Hospital","authors":"Saima Rahman, Nasima Begum, Ashik Mahmud","doi":"10.3329/jrpmc.v9i1.72712","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72712","url":null,"abstract":"Background: Eclampsia is a severe and life-threatening complication of pregnancy, characterized by the onset of seizures in a woman with preeclampsia. This hypertensive disorder of pregnancy is associated with a range of maternal complications, presenting a significant challenge in obstetric care. Maternal complications of this nature can significantly affect both maternal and perinatal health, potentially leading to higher rates of mortality and morbidity. Objective: This study was aimed to evaluate the morbidity and mortality of eclampsia in Brahmanbaria Medical College and Hospital. Methods: This cross-sectional observational study was conducted at Brahmanbaria Medical College and Hospital, Brahmanbaria, Bangladesh, from January 2021 to December 2021. The study included 56 pregnant women with eclampsia purposively. Demographic and clinical information was recorded, and data analysis and dissemination were carried out using MS Office tools. Results: Regarding perinatal outcomes, 80% of cases resulted in live births, with a 57% survival rate. Among live births, 4% experienced post-birth mortality, and 11% faced early neonatal death. Among live births (n=45), a significant 69% experienced intrauterine growth restriction (IUGR). Maternal complications included abruptio placenta in 32% of cases, HELLP syndrome in 5%, and maternal death occurred in 5% of cases. Conclusions: Eclampsia assessment shows complex perinatal and maternal outcomes. Live births are common, but survival is challenging. High post-birth and neonatal mortality highlight newborn vulnerability. Intrauterine growth restriction (IUGR) worsens newborn health concerns. Maternal issues like abruptio-placenta, HELLP syndrome, and maternal death further complicate matters.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 39-43","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"262 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Association of Lupus Erythematosus with Patients of Vitiligo: A Case Control Study","authors":"Mohammad Abul Kalam Azzad, Muhammad Munir Rashid, Syeda Fateha Noor, Abu Hena Chowdhury, L. Khondoker","doi":"10.3329/jrpmc.v9i1.72711","DOIUrl":"https://doi.org/10.3329/jrpmc.v9i1.72711","url":null,"abstract":"Background: Vitiligo is an idiopathic acquired depigmentary skin/ mucous membrane disorder. Lupus erythematosus and vitiligo are diseases of autoimmune origin. A genetic explanation for the association between lupus erythematosus and vitiligo has recently been attempted. Objective: To find out the association of lupus Erythematosus in patients of vitiligo. Methods: This case control study was carried out in the department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of January 2023 to December 2023. A total of 180 patients with and without vitiligo from both genders and different ages for case and control groups were included in the study based on inclusion and exclusion criteria. Patients were divided into two groups, 90 patients with vitiligo as cases and 90 patients without vitiligo (healthy subjects) as controls. Wood’s lamp examination was performed for diagnosis of vitiligo. LE was diagnosed based on ACR criteria and laboratory test including Complete blood count, Urinalysis, ANA, anti-ds DNA, VDRL and Skin biopsy. Patients with lupus erythematosus and patients without lupus erythematosus were considered as group I and group II respectively. Results: In this study, the mean age was found 41.7±12.8 years in case group (Vitiligo) and 42.1±13.6 years in control group (Healthy subjects).More than half (51.1%) of the patients were female in case group and 41(45.6%) in control group. There was no significant difference was found regarding age, sex, anemia, leucopenia, thrombocytopenia, proteinuria, ANA and anti ds-DNA. Family history of vitiligo was significantly higher in vitiligo patients than healthy patients (26.7% vs 12.2%). The majority 45(50.0%) presented with generalize followed by 21(23.3) acrofacial, 13(14.4%) focal, 10(11.1%) segmental and 1(1.1%) mucosal of vitiligo. Lupus erythematosus was higher in vitiligo patients than healthy patients (4.4% vs 1.1%) but the difference was not statistically significant between the two groups (p=0.184). Conclusions: This study concluded that family history of vitiligo was significantly higher in vitiligo patients than healthy patients. Lupus erythematosus was higher in vitiligo patients than healthy patients, but not statistically significant.\u0000J Rang Med Col. March 2024; Vol. 9, No. 1: 33-38","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"296 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141012468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Estimated Glomerular Filtration Rate in Obese Male Adults and Its Correlation with BMI","authors":"Safina Akhter, C. Sarkar, Atm Zoadur Rahim Zahid","doi":"10.3329/jrpmc.v8i1.65034","DOIUrl":"https://doi.org/10.3329/jrpmc.v8i1.65034","url":null,"abstract":"Background: Overweight and obesity has been announced as a global epidemic by The World Health Organization. These conditions have strong associations with renal function impairment.\u0000Objectives: To evaluate the estimated glomerular filtration rate (eGFR) in obese male adults and to observe the correlation of eGFR with body mass index (BMI).\u0000Methods: This cross-sectional analytical study was conducted at the Department of Physiology, Rangpur Medical College, Rangpur. After briefing about objectives, adult males who met the inclusion and exclusion criteria were enrolled in the study by consensus. The study involved 60 people who were divided into two groups: apparently healthy adult males of average weight (Group A) and apparently healthy adult males who were obese (Group B). The subjects were selected from different districts of the city of Rangpur. Their body mass index & serum creatinine were measured. eGFR was calculated by Cockcroft-Gault equation using serum creatinine. For statistical analysis, unpaired t-test and Pearson’s correlation coefficient test were performed as applicable by computer-based SPSS–25.0 for windows. Regarding the interpretation of results, p≤0.05 was accepted as significant.\u0000Results: The mean of estimated glomerular filtration rate was significantly (p≤ 0.001) lower in obese male adults than in normal-weight male adults. This study also found a highly significant (p≤0.05) negative correlation of eGFR (r = -0.317) with body mass index.\u0000Conclusion: eGFR is reduced in obese male adults, and it is negatively correlated with BMI. Regular body mass index screening is recommended as an easy and effective means of assessing body weight.\u0000J Rang Med Col. March 2023; Vol. 8, No. 2:27-32","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129351660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isoniazid-induced Encephalopathy in a Patient with Pott’s Disease with Chronic Kidney Disease: A Case Report","authors":"Md Helal Miah, Md Ahad Bakas, Md Kamal Hossein, T. Begum, Md Shafiul Alam, M. Kabir, Abu Said Md Rahenur Mondol, Md Ruhul Amin Sarkar, M. Anwar, Shahed Jahan, Md Mahfuzer Rahman","doi":"10.3329/jrpmc.v8i1.65066","DOIUrl":"https://doi.org/10.3329/jrpmc.v8i1.65066","url":null,"abstract":"We report an isoniazid-induced encephalopathy in a man with chronic renal failure. Drug-induced encephalopathy is a common side effect of many drugs. Isoniazid (INH), a first-line drug for tuberculosis, can cause encephalopathy in patients with chronic kidney disease (CKD). For Pott's disease of the thoracic spine, he received rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine and prednisolone. But the patient is free of pyridoxine for two and a half months. Subsequently, after treatment, the patient experienced recurrent episodes of altered consciousness, irrelevant conversations, and disorientation. After ruling out other causes, isoniazid-induced encephalopathy was suspected and confirmed by improvement of symptoms after discontinuation of high-dose isoniazid and pyridoxine.\u0000J Rang Med Col. March 2023; Vol. 8, No. 1:72-75","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127403839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Household Water, Sanitation, Hygiene Facilities and Practices in Selected Villages of Taraganj Upazilla, Rangpur","authors":"Munira Begum, Md Shahriar Morshed, Rehnuma Islam, Most Masuma Islam Nisa","doi":"10.3329/jrpmc.v8i1.65060","DOIUrl":"https://doi.org/10.3329/jrpmc.v8i1.65060","url":null,"abstract":"Background: Water, sanitation and hygiene (WASH) facilities are considered a basic human necessity for survival and well-being, without these basic needs the health condition of millions of people, especially children and women are at risk. Bangladesh is vulnerable in this regard.\u0000Objectives: The study aimed to assess household water, sanitation and hygiene facilities and practices in selected villages of Taraganj Upazilla, Rangpur.\u0000Methods: This cross-sectional study was conducted among 341 rural households from six villages of Taraganj Upazilla, Rangpur district using a pretested semi-structured questionnaire and an observation checklist. Data were collected through face-to-face interview and observing the facilities.\u0000Result: The respondents of this study were female predominant. Male: female ratio was 1:3 and their average age was 38.16(±14.03) years. Every household were using improved source of water for both drinking and other domestic purposes but only 4.7% households safely treated water for drinking and only in 17.9% households water source was found 50 feet or more from the latrine. About 70.7% respondents kept their drinking water storage container over shelf/table, covered it with lid (65.0%) and 90.4% containers were found clean during observation. Around 95.6% households used an improved toilet facility and in 45.7 % household latrine was situated in their own dwellings. Although on observation of latrines, water collection or storage facility, hand washing facility and soap or detergent availability near them were found 63.2%, 64.4% and 59.9% households respectively. Still 2.1% households had no toilet facility at all. Nearly 19.4% respondents shared their toilet facility with other households. About 90.3% households safely disposed their children’s stool. Majority of respondents told that they used soap during washing hands before meal (84.8%) and after defecation (98.2%).During observation of the site for hand washing, water supply and soap or detergent availability were found in 97.7% and 83.3% households respectively. Good practices for drinking water, sanitation and hygiene were found among 4.7%, 71.6% and 92.7% households respectively.\u0000Conclusion: These findings are suggestive of need to come up with strategies of health education and promotion to ensure that rural households understand the importance of safe treatment of drinking water, safe disposal of child’s stool and safe distance of latrine from drinking water source in order to prevent spread of diseases. Effective policies should be developed by policymakers, safe distance of latrine from drinking water source and media and communication specialists should convey clear messages for everyone, particularly illiterate rural population.\u0000J Rang Med Col. March 2023; Vol. 8, No. 2:53-58","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131741238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Hepatitis B Infection Among Healthy Blood Donors in Rangpur, Bangladesh","authors":"Jobaida Jannat, Md. Ashekur Rahman, Mufeq Mahmud, Md. Zia Hayder Bosunia, A. Rana, Khousnoor Hanif","doi":"10.3329/jrpmc.v8i1.65059","DOIUrl":"https://doi.org/10.3329/jrpmc.v8i1.65059","url":null,"abstract":"Background: Transfusion transmitted infection (TTIs) is still an alarming issue associated with blood transfusion, as hepatitis B remains a critical public health concern in a country like Bangladesh. The predisposition of the prevalence of HBsAg infection among healthy blood donors even in a tertiary-level hospital could be a strategy for scheming and observing this problem.\u0000Methods: A cross-sectional study was conducted among all samples of a total of 11,566 units of blood screening for hepatitis B surface antigen at Rangpur Medical College Hospital, Rangpur from January 2021 to December, 2021. The prevalence of HBV infection was measured to observe the trends. Data were collected by non-probability convenient sampling, maintaining inclusion and exclusion criteria. Face-to-face interviews, blood grouping tests, and hepatitis B surface antigen (HBsAg) screening were conducted.\u0000Results: About 66% of the blood donors were between 18 and 30 years of age, and 89.6% of them were males. All the donors were replacement donors who came voluntarily. The overall seroprevalence rate of HBV among all healthy blood donors was 1.09%. About 98.4% of HBsAg-positive blood donors were males and only 1.6% were female. Hepatitis B infection was more prevalent in the 28–36 years age group and least prevalent among those older than 48 years of age.\u0000Conclusion: The decreasing trend in the prevalence of HBV infection might be the result of improvement in donor recruitment and selection, built-up awareness, proper TTIs screening, HBV vaccination and possibly decreasing HBV infection prevalence in the general population.\u0000J Rang Med Col. March 2023; Vol. 8, No. 2:49-52","PeriodicalId":370900,"journal":{"name":"Journal of Rangpur Medical College","volume":"213 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121721552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}