Md Helal Miah, Md Ahad Bakas, Md Kamal Hossein, T. Begum, Md Shafiul Alam, M. Kabir, Abu Said Md Rahenur Mondol, Md Ruhul Amin Sarkar, M. Anwar, Shahed Jahan, Md Mahfuzer Rahman
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引用次数: 0
摘要
我们报告一个异烟肼引起的慢性肾衰竭的脑病。药物性脑病是许多药物的常见副作用。异烟肼(INH)是治疗结核病的一线药物，可引起慢性肾病(CKD)患者的脑病。对于胸椎的波特病，他接受利福平、INH、吡嗪酰胺和乙胺丁醇联合吡哆醇和强的松龙治疗。但病人已经两个半月不用吡哆醇了。随后，在治疗后，患者经历了反复发作的意识改变、不相关的谈话和定向障碍。排除其他原因后，疑似异烟肼所致脑病，停药后症状改善，证实为异烟肼所致脑病。J Rang Med Col. 2023年3月;第八卷，第1章72-75节
Isoniazid-induced Encephalopathy in a Patient with Pott’s Disease with Chronic Kidney Disease: A Case Report
We report an isoniazid-induced encephalopathy in a man with chronic renal failure. Drug-induced encephalopathy is a common side effect of many drugs. Isoniazid (INH), a first-line drug for tuberculosis, can cause encephalopathy in patients with chronic kidney disease (CKD). For Pott's disease of the thoracic spine, he received rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine and prednisolone. But the patient is free of pyridoxine for two and a half months. Subsequently, after treatment, the patient experienced recurrent episodes of altered consciousness, irrelevant conversations, and disorientation. After ruling out other causes, isoniazid-induced encephalopathy was suspected and confirmed by improvement of symptoms after discontinuation of high-dose isoniazid and pyridoxine.
J Rang Med Col. March 2023; Vol. 8, No. 1:72-75
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