三级甲等医院育龄妇女患乳腺癌的模式、风险因素和临床病理学评估

Md Rasedul Haque, Md Amzad Hossain
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摘要

背景:乳腺癌是孟加拉国女性的主要癌症,由于城市化和采用西方生活方式,乳腺癌发病率大幅上升。研究目的本研究旨在系统了解育龄妇女乳腺癌的发病模式、风险因素和临床病理评估。研究方法这是一项横断面观察研究,从 2022 年至 2023 年期间达卡联合军事医院外科经组织病理学确诊的 50 名乳腺癌患者中收集数据。研究结果大多数病例的年龄为 41-45 岁(42%),平均年龄为 43.55 岁(SD-/+9.63)。浸润性导管癌是最常见的亚型,占 86%,其次是导管原位癌(8%)。2%的病例为无子宫,46%的病例有两个孩子。第一胎的中位年龄为 21 岁。很大一部分患者(16%)有乳腺癌家族史。98%的患者有哺乳史。结论在孟加拉国,乳腺癌越来越多地发生在年轻群体中,研究结果表明,月经初潮年龄、头胎生育年龄、胎次、母乳喂养史和家族史等不同因素对女性构成了较高的乳腺癌风险。J Rang Med Col,2024 年 3 月;第 9 卷,第 1 期:16-21 页
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pattern of Breast Cancer in Women at Child-bearing Age, its Risk Factors and Clinicopathological Evaluation in Tertiary Level Hospital
Background: Carcinoma breast is the leading cancer in female in Bangladesh, increasing significantly due to urbanization and adoption of western life style. Objective: This study aimed to systematically understand the pattern of breast cancer, its risk factors and clinicopathological evaluation in women at their childbearing age. Methods: A cross sectional observational study, data was collected from 50 patients of histopathologically confirmed breast cancer in the department of Surgery, Combined Military Hospital, Dhaka from 2022 to 2023. Results: The majority of the cases were 41-45(42%) years age with mean presentation was 43.55 (SD-/+9.63) years. Invasive ductal carcinoma was the most common subtype 86%, followed by ductal carcinoma in situ (8%). Of the cases 2% were nullipara and 46% had two children. Median age of at 1st birth was 21 years. A significant proportion (16%) had family history of breast cancer. 98% patients gave history of breast feeding. Conclusions: Breast cancer is increasingly occurring in younger age groups in Bangladesh, results suggested a mixture of different factors in women like age of menarche, age of first child birth, parity, history of breast feeding and family history poses higher risk for breast cancer. J Rang Med Col. March 2024; Vol. 9, No. 1:16-21
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