Sleep Medicine: X最新文献

{"title":"Subjective and objective sleep quality assessment in adolescent patients with inflammatory bowel disease","authors":"Holly Breeden ,&nbsp;Elizabeth McDonough ,&nbsp;Amanda Glinky ,&nbsp;Rebecca Wallace ,&nbsp;Robbie Beyl ,&nbsp;Colleen LeBlanc","doi":"10.1016/j.sleepx.2024.100125","DOIUrl":"10.1016/j.sleepx.2024.100125","url":null,"abstract":"<div><h3>Objectives</h3><p>There is a link between inflammatory bowel disease (IBD) and poor sleep quality that is presumed to be multifactorial. The purpose of this study was to identify factors that impact sleep quality in this group including clinical disease activity, depression, anxiety, quality of life, and disordered social media use through questionnaires.</p></div><div><h3>Methods</h3><p>This prospective study analyzed sleep quality in adolescent patients ages 13 to 18 with a diagnosis of IBD using objective data from wrist actigraphy and subjective report from the Pittsburgh Sleep Quality Index (PSQI). Additional screeners including the Short Pediatric Crohn's Disease Activity Index or Pediatric Ulcerative Colitis Activity Index, Pediatric Quality of Life Inventory Gastrointestinal Symptoms Module, Generalized Anxiety Disorder 7-item screener, Patient Health Questionnaire depression screener, and Social Media Disorder scale were also collected.</p></div><div><h3>Results</h3><p>Twenty-three subjects enrolled and 16 completed questionnaires. 62.5 % of participants were in clinical remission and the remaining 37.5 % had mild to severe clinical IBD activity. Poor subjective sleep quality was associated with a shorter duration of sleep time and an increased clinical disease activity score. Patients in clinical remission slept for a longer duration than those with mild IBD activity.</p></div><div><h3>Conclusions</h3><p>This study did not identify a significant relationship between sleep quality and psychosocial factors in the adolescent population with IBD, though their influence cannot be discounted. There was a connection between the presence of disease activity and shorter sleep duration. Similarly, PSQI scores correlated with sleep time but not sleep quality.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000235/pdfft?md5=8932590a994a63029c74287f14eabf12&pid=1-s2.0-S2590142724000235-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between Japanese calligraphy practice and sleep quality in community-dwelling older adults: A cross-sectional Study","authors":"Georg von Fingerhut ,&nbsp;Keitaro Makino ,&nbsp;Osamu Katayama ,&nbsp;Ryo Yamaguchi ,&nbsp;Daiki Yamagiwa ,&nbsp;Jessica K. Bone ,&nbsp;Hiroyuki Shimada","doi":"10.1016/j.sleepx.2024.100124","DOIUrl":"10.1016/j.sleepx.2024.100124","url":null,"abstract":"<div><h3>Background</h3><p>Sleep disturbances, such as insomnia, are common among the elderly population and have been associated with negative health outcomes. Japanese calligraphy is a traditional art practice previously associated with various health benefits, such as stress reduction and improved cognitive function; however, its association with sleep quality has not been fully explored.</p></div><div><h3>Methods</h3><p>This cross-sectional study included 21,207 subjects with basic attributes, health status, depressive symptoms, artistic practices, and sleep habits. Individuals who satisfied the chronic insomnia criteria were categorized into the following subtypes: sleep onset latency (SOL) insomnia, early morning awakening (EMA) insomnia, and wake after sleep offset (WASF) insomnia. The <em>t</em>-test, chi-square test, and logistic regression analysis were used to determine the association between Japanese calligraphy practice and sleep quality.</p></div><div><h3>Results</h3><p>In this study, 17,597 elderly Japanese individuals were included, among whom 13.7 % practiced Japanese calligraphy. Regarding sleep characteristics, 32.0 % had chronic insomnia, 13.1 % had SOL insomnia, 9.1 % had EMA insomnia, and 14.2 % had WASF insomnia. Japanese calligraphy practice was associated with lower rates of chronic insomnia (odds ratio [OR] = 0.85, 95 % confidence interval (CI) = 0.76–0.95), including SOL insomnia (OR = 0.84, 95 % CI = 0.71–0.98), and EMA insomnia (OR = 0.80, 95 % CI = 0.66–0.97) but had no significant association with WASF insomnia.</p></div><div><h3>Conclusions</h3><p>This study suggests that Japanese calligraphy practice is associated with lower odds of insomnia, particularly SOL and EMA insomnia. Calligraphy may be an effective nonpharmacological intervention for insomnia and poor sleep quality among elderly Japanese individuals.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100124"},"PeriodicalIF":0.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000223/pdfft?md5=84ea5440c11f90ccd4129d5258462969&pid=1-s2.0-S2590142724000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial","authors":"Heather A. Hausenblas ,&nbsp;Tarah Lynch ,&nbsp;Stephanie Hooper ,&nbsp;Aahana Shrestha ,&nbsp;Doug Rosendale ,&nbsp;Jennifer Gu","doi":"10.1016/j.sleepx.2024.100121","DOIUrl":"10.1016/j.sleepx.2024.100121","url":null,"abstract":"<div><h3>Objective/Background</h3><p>Sleep problems challenge overall wellbeing. Magnesium has been implicated to benefit sleep, although the clinical evidences varied based on the magnesium source used. Magnesium L-threonate (MgT) is a promising intervention due to its brain bioavailability and effects on cognition, memory and mood. We investigated MgT supplementation on sleep quality and daily function.</p></div><div><h3>Patients/methods</h3><p>Eighty 35–55-year-olds with self-assessed sleep problems participated in a randomized, double-blind, placebo-controlled, parallel-arm study, taking 1 g/day of MgT or placebo for 21 days. Sleep and daily behaviors were measured subjectively using standardized questionnaires including the Insomnia Severity Index, Leeds Sleep Evaluation Questionnaire, and Restorative Sleep Questionnaire, and objectively using an Oura ring. The Profile of Mood States questionnaire and a daily diary were used to evaluate mood, energy and productivity, and record any safety concerns.</p></div><div><h3>Results</h3><p>The MgT group maintained good sleep quality and daytime functioning, while placebo declined. From objective Oura ring measurements, MgT significantly (p &lt; 0.05) improved <em>vs</em> placebo deep sleep score, REM sleep score, light sleep time, and activity and readiness parameters activity score, activity daily movement score, readiness score, readiness activity balance, and readiness sleep balance. From subjective questionnaires, MgT significantly (p &lt; 0.05) improved <em>vs</em> placebo behavior upon awakening, energy and daytime productivity, grouchiness, mood and mental alertness. MgT was safe and well tolerated.</p></div><div><h3>Conclusions</h3><p>This showed MgT improved sleep quality, especially deep/REM sleep stages, improved mood, energy, alertness, and daily activity and productivity. These are consistent with how MgT works in neuron cells and animal models, suggesting broader positive impacts on overall brain health.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100121"},"PeriodicalIF":0.0,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000193/pdfft?md5=ca2c05f6b86f85b46bcdd8282887e714&pid=1-s2.0-S2590142724000193-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141997647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep duration in middle-aged years of life predicts the age of diagnosis of Parkinson's disease","authors":"Cayla E. Clark,&nbsp;Joshua Gold,&nbsp;B. Rhett Rigby","doi":"10.1016/j.sleepx.2024.100123","DOIUrl":"10.1016/j.sleepx.2024.100123","url":null,"abstract":"<div><h3>Introduction</h3><p>Chronic short sleep duration (i.e., &lt;7 h sleep daily) could reduce the brain's ability to attenuate toxin and protein accumulation, which may contribute to Parkinson's disease (PD). The purpose of this study was to characterize the relationship between self-reported sleep duration from adolescence to adulthood and the age of diagnosis in people with PD. A secondary purpose was to characterize the interaction between sleep duration and physical activity through the lifespan on the age of PD diagnosis.</p></div><div><h3>Methods</h3><p>A secondary data analysis was performed using the Fox Insight data set. Multiple regression analysis was used to determine the age range that sleep duration best predicted the age of diagnosis of PD. Hierarchical linear multiple regression was performed to assess if self-reported sleep duration, physical activity, and their interaction predicted the age of diagnosis for PD, after accounting for sociodemographic factors.</p></div><div><h3>Results</h3><p>Both sleep (p &lt; 0.001) and physical activity time (p = 0.013) significantly predicted the of age of onset of PD. In contrast, there was no evidence to support an interaction of sleep by physical activity on the age of diagnosis of PD. Sleep duration at 46–55 years maintained significance after controlling for education, income, race, ethnicity, and sex (p &lt; 0.001). Weekly duration of time spent performing moderate-intensity physical activity was added as an input variable.</p></div><div><h3>Conclusion</h3><p>Sleep duration significantly predicts the age of diagnosis of PD, with shorter sleep duration associated with a younger age of diagnosis of PD.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000211/pdfft?md5=4f6742e9da7aaedc78a6f5644e4ed6b8&pid=1-s2.0-S2590142724000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142040395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RESTORE: Once-nightly oxybate dosing preference and nocturnal experience with twice-nightly oxybates","authors":"Asim Roy ,&nbsp;Thomas Stern ,&nbsp;John Harsh ,&nbsp;J. Douglas Hudson ,&nbsp;Akinyemi O. Ajayi ,&nbsp;Bruce C. Corser ,&nbsp;Emmanuel Mignot ,&nbsp;Adrian Santamaria ,&nbsp;Anne Marie Morse ,&nbsp;Brian Abaluck ,&nbsp;Sally Ibrahim ,&nbsp;Paula K. Schweitzer ,&nbsp;Katie Lancaster ,&nbsp;Jordan Dubow ,&nbsp;Jennifer Gudeman","doi":"10.1016/j.sleepx.2024.100122","DOIUrl":"10.1016/j.sleepx.2024.100122","url":null,"abstract":"<div><h3>Objective/Background</h3><p>Preference for extended-release, once-nightly sodium oxybate (ON-SXB, FT218) vs twice-nightly immediate-release (IR) oxybate was assessed in participants switching from IR oxybate to ON-SXB in an open-label/switch study, RESTORE (NCT04451668).</p></div><div><h3>Patients/Methods</h3><p>Participants aged ≥16 years with narcolepsy who completed the phase 3 REST-ON trial, were oxybate-naive, or were on a stable IR oxybate dose (≥1 month) were eligible for RESTORE. For participants who switched from twice-nightly dosing to ON-SXB, initial doses were closest or equivalent to their previous nightly IR oxybate dose. These participants completed a questionnaire at baseline about nocturnal adverse events associated with the middle-of-the-night IR oxybate dose in the preceding 3 months, a preference questionnaire after 3 months of stable-dose ON-SXB, and an end-of-study (EOS) questionnaire.</p></div><div><h3>Results</h3><p>There were 130 switch participants; 92/98 (93.9 %) who completed the preference questionnaire preferred ON-SXB. At baseline, 69.2 % reported missing their second IR oxybate dose at least once; in these cases, 80 % felt worse the next day. Approximately 39 % reported taking a second nightly IR oxybate dose &gt;4 h after the first dose, 51 % of whom felt somewhat to extremely groggy/unsteady the next morning; 120 participants (92 %) reported getting out of bed after their second oxybate dose. Of those, 9 (8 %) reported falls and 5 (4 %) reported injuries. Of the switch participants who completed the EOS questionnaire, 91.2 % felt better able to follow the recommended ON-SXB dosing schedule.</p></div><div><h3>Conclusions</h3><p>The second nightly IR oxybate dose presents significant treatment burdens and adherence concerns. Participants overwhelmingly preferred the once-nightly dosing regimen of ON-SXB.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100122"},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S259014272400020X/pdfft?md5=774141c3ceeff18615ce020ae63dbf2d&pid=1-s2.0-S259014272400020X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142040394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of sleep disturbance across two waves of the COVID-19 pandemic among nursing staffs","authors":"Pei-Jhen Wu ,&nbsp;Wen Chun Wang ,&nbsp;Chin-Lien Liu ,&nbsp;Guei-Ging Lin ,&nbsp;Ying-Ying Lo ,&nbsp;Frank Huang-Chih Chou","doi":"10.1016/j.sleepx.2024.100120","DOIUrl":"10.1016/j.sleepx.2024.100120","url":null,"abstract":"<div><h3>Objectives</h3><p>COVID-19 has impacted human lifestyles, including sleep quality. For nursing staff, sleep disorders not only impact their health and daily lives but also have implications for patient safety. The objective of this study is to explore the impact of the COVID-19 pandemic on the psychological and social aspects of nursing staff and the factors influencing their sleep quality through a two-wave survey.</p></div><div><h3>Methods</h3><p>Nursing staff from a psychiatric hospital in southern Taiwan were recruited in two waves during the COVID-19 epidemic. The level of sleep disturbance and related variables, such as Lo's Healthy and Happy Lifestyle Scale (LHHLS) and Societal Influences Survey Questionnaire (SISQ), were collected through self-report questionnaires. Factors related to the level of sleep disturbance were examined using univariate linear regression and multilevel linear regression.</p></div><div><h3>Results</h3><p>508 nursing staff members were included in the study, with 254 members in each wave. A significant difference was found between the two waves in the positive thinking of LHHLS and all subscales of SISQ. During the second wave, sleep disturbances were mainly related to self-efficacy, positive thinking, social anxiety, and social desirability. At the fourth wave, sleep disturbances were mainly related to self-efficacy, positive thinking, and social anxiety. However, these effects change when the trend of the epidemic shifts, and other factors are taken into account.</p></div><div><h3>Conclusions</h3><p>This study analyzed the factors related to the sleep quality of nursing staff during the COVID-19 pandemic. We preliminarily explored the impact of the COVID-19 pandemic on the sleep quality of nursing staff. However, determining whether the end of the epidemic has reduced the impact on nursing staff requires further research.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000181/pdfft?md5=ac556863c1da9713255093ad2742403e&pid=1-s2.0-S2590142724000181-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142076066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of the Indian Sleepiness Scale to assess excessive daytime sleepiness in patients with Obstructive Sleep Apnea","authors":"Uma Maheswari Krishnaswamy ,&nbsp;Kavitha Venkatnarayan ,&nbsp;Sumithra Selvam ,&nbsp;Chitra Veluthat ,&nbsp;Priya Ramachandran ,&nbsp;Uma Devaraj","doi":"10.1016/j.sleepx.2024.100119","DOIUrl":"https://doi.org/10.1016/j.sleepx.2024.100119","url":null,"abstract":"<div><h3>Background</h3><p>Excessive daytime sleepiness (EDS), a cardinal symptom of obstructive sleep apnea (OSA) is assessed using Epworth Sleepiness Scale (ESS). Some limitations of ESS include graded responses, inapplicable situations and equal scores for active and passive situations. To overcome these limitations, we developed a novel sleepiness scale and evaluated its performance in patients with OSA.</p></div><div><h3>Methods</h3><p>The study was executed in multiple phases. After determining applicability of items in the ESS, a 6-item questionnaire was developed comprising OSA symptoms and self-reported ‘sleepy’ situations, dichotomized responses and weighted scoring. After content and face validation by experts, the scale was tested for applicability and its performance was compared with ESS in patients with suspected OSA.</p></div><div><h3>Results</h3><p>In phase I, applicability of ESS was tested in 189 participants, of whom 98 (51.8 %) participants found multiple items inapplicable.</p><p>In phase II, 34 self-reported sleepy situations from 200 participants were narrowed down to a 6-item questionnaire, based on expert validation. This scale was named the Indian Sleepiness Scale (ISS) and was tested for applicability in phase III in 226 participants from diverse literacy backgrounds, who found all situations applicable.</p><p>In phase IV, ISS and ESS were administered to 335 patients with suspected OSA. OSA was confirmed on polysomnography in 294 (87.7 %) patients. A cut-off score of ≥6 was derived for ISS; at this cut-off score, the ISS which was more sensitive than ESS (71.1 % vs 43.2 %).</p></div><div><h3>Conclusions</h3><p>The Indian Sleepiness Scale was found to be widely applicable and more sensitive than ESS for sleepiness evaluation in patients with OSA.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100119"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S259014272400017X/pdfft?md5=1253d839cc58d1daba51c2a073067f08&pid=1-s2.0-S259014272400017X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141606949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"REM sleep behavior disorder and Prodromal Parkinson’s Disease in patients with Essential Tremor","authors":"Paulo Bugalho ,&nbsp;Bruna Meira ,&nbsp;André Pinho ,&nbsp;Rita Ventura ,&nbsp;Marta Magriço ,&nbsp;Miguel Serôdio ,&nbsp;Danna Krupka ,&nbsp;Vítor Mendes Ferreira","doi":"10.1016/j.sleepx.2024.100118","DOIUrl":"https://doi.org/10.1016/j.sleepx.2024.100118","url":null,"abstract":"<div><p>Several studies suggested the presence of non-motor symptoms in Essential Tremor (ET), including REM sleep behavioral disorder (RBD). RBD is an essential criterion for Prodromal Parkinson's Disease (PPD), suggesting a link between ET and PD. Our objective was to assess the prevalence and features of ET patients with RBD and PDD.</p><p>RBD was diagnosed by questionnaire screening, followed by polysomnography. PPD risk factors and prodromic markers were assessed with a structured protocol. Patients were characterized regarding tremor features. ET patients with RBD (ET-RBD) and PPD (ET-PPD) were compared to patients without RBD (ET-nonRBD) and without PPD (ET-nonPPD), respectively. ET-RBD patients were also compared with a group of isolated RBD (iRBD) regarding PPD features.</p><p>We assessed a total of 64 ET patients. Five (8.3 %) and 4 (6.3 %) had criteria for RBD and PPD, respectively. ET-RBD patients did not differ from ET-nonRBD except for a higher prevalence of PPD. There were no significant differences between ET-RBD and iRBD (n = 12) groups. ET-PPD had a higher prevalence of positive DaT-Scans and RBD compared to ET-nonPPD. Three ET-RBD patients had PPD and 3 ET-PPD had RBD.</p><p>Both RBD and PPD are more frequent in ET patients than in general aged population but not related with specific tremor features. ET-RBD patients did not differ significantly from iRBD patients, a group prone to develop PD. These data suggest a link between ET and PD and are in accordance with studies showing an increase incidence of lewy-body pathology and PD in ET populations.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100118"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000168/pdfft?md5=b4475837bfa909d9c7ce85474b7d4c19&pid=1-s2.0-S2590142724000168-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141583072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of digital media use with sleep habits in school children: A cross-sectional study","authors":"Doreswamy Chandranaik,&nbsp;Jagdish Prasad Goyal,&nbsp;Kuldeep Singh,&nbsp;Prawin Kumar","doi":"10.1016/j.sleepx.2024.100117","DOIUrl":"https://doi.org/10.1016/j.sleepx.2024.100117","url":null,"abstract":"<div><h3>Background</h3><p>The use of digital media (DM) is increasing among school-children, which can affect their sleep habits. The primary objective of this study was to evaluate the association of DM use with sleep habits in school-children.</p></div><div><h3>Methods</h3><p>It was a cross-sectional study of healthy school children. Sleep habits and DM use were assessed using the Children's Sleep Habits Questionnaire (CSHQ) and SCREENS-Q, respectively. The Pearson correlation coefficient was used to establish the correlation between the two variables. Logistic regression analysis was performed to quantify the extent of association between variables. A p-value &lt;0.05 was considered statistically significant.</p></div><div><h3>Results</h3><p>A total of 205 children were enrolled with a mean (SD) age of 7.1 (2.1) years. The mean (SD) sleep duration was 7.58 (0.80) hours. The mean (SD) CSHQ score was 50.6 (5.1). Use of DM was observed in 204 (99.5 %) children. On multivariate logistic regression analysis, DM use ≥2 h/day was significantly associated with higher CSHQ score (OR 1.28, 95%CI 1.18–1.40; p = 0.001). Sleep domains significantly affected by DM use ≥2 h/day were bedtime resistance (OR 1.55, 95 % CI 1.24–1.94; p &lt; 0.001), sleep duration (OR 0.40, 95 % CI 0.28–0.58:p &lt; 0.001), sleep anxiety (OR 1.69, 95%CI 1.40–2.04:p &lt; 0.001), night awakening (OR 4.81 95 % CI 2.98–7.78:p &lt; 0.001), parasomnias (OR 1.86, 95 % CI 1.45–2.38:p &lt; 0.001), and daytime sleepiness (OR1.89,95 % CI 1.52–2.36: p &lt; 0.001). DM use 30 min before bedtime was significantly associated with a higher CSHQ score (OR 1.32, 95 % CI 1.20–1.45; p &lt; 0.001). In bivariate regression analysis, DM use ≥2 h/day was associated with poor academic performance (OR 2.36 95 % CI 1.28–4.35; p 0.006).</p></div><div><h3>Conclusion</h3><p>This study has shown that the average sleep duration in children was shorter than the recommended duration. DM use was common in school children and it has a significant association with sleep habits especially with use of ≥2 h/day and 30 mints before bedtime. It was also associated with poor academic performance. Public awareness on effect of DM use in school children is the need of the hour.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"8 ","pages":"Article 100117"},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000156/pdfft?md5=7041413eb96720aef7ca516630972a9d&pid=1-s2.0-S2590142724000156-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141324836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report on melatonin overdose: Cause and concern","authors":"Richa Tripathi,&nbsp;Hina Bano,&nbsp;Mohd Rashid Alam","doi":"10.1016/j.sleepx.2024.100116","DOIUrl":"10.1016/j.sleepx.2024.100116","url":null,"abstract":"<div><p>Melatonin, the primary hormone secreted by the pineal gland, regulates central and peripheral oscillators and adapts the internal environment to the external one through MT1 and MT2 receptors. The authors present a case of 16-year-old male intentionally overdosed on 900mg of melatonin (180 tablets) and 10 tablets of 0.5mg alprazolam. Admitted to the emergency department, he was extremely drowsy and minimally responsive with a Glasgow coma scale score of 8/15. Vital signs were stable, and no renal or liver dysfunction was noted. Elevated total leucocyte count and positive benzodiazepine urine test were observed. Gastric lavage was performed, and toxicology reports showed blood alprazolam levels at 0.15 mg/litre eight hours post-overdose. The patient regained consciousness 32 hours post-ingestion and was transferred to the psychiatry unit. This case underscores the increasing abuse of melatonin due to its easy availability and lack of regulation. Although melatonin has a low toxicity potential, side effects and interactions with other drugs can be severe. Supportive measures and vital sign control are crucial in overdose treatment.</p></div>","PeriodicalId":37065,"journal":{"name":"Sleep Medicine: X","volume":"7 ","pages":"Article 100116"},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590142724000144/pdfft?md5=e509b80493c850559efa81b5db5319bd&pid=1-s2.0-S2590142724000144-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141133557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}