{"title":"Mechanical Property Detection of Cardiomyocytes by Atomic Force Microscopy","authors":"Jianjun Dong, Bowei Wang, Xingyue Wang, Rui Wang, Jiani Li, Kaige Qu, Ying Wang, Huimiao Wei, Zuobin Wang","doi":"10.1109/3M-NANO56083.2022.9941570","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941570","url":null,"abstract":"Cells are the basic unit of live activities, and the cell mechanical properties can effectively reflect their functions and statuses. Furthermore, the cell mechanical properties can effectively characterize the cellular function. In this work, the atomic force microscopy (AFM) was used to detected the mechanical properties of cardiomyocytes. We measured Young's modulus, adhesion and the beating force of nuclei, cytoplasm and margin of cardiomyocytes extracted from a 1–3 day newborn mouse. The mechanical properties of different areas of the cardiomyocytes were statistical analysis provides useful information for the diagnosis of myocardial disease and the pharmaceutical testing and screening.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116456286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of a 3D-printed Monolithic Compliant Tip-tilt-z Stage for Micro-alignment","authors":"Huaxian Wei, Jian Yang, Yuanchao Li, Zhouwu Chen","doi":"10.1109/3M-NANO56083.2022.9941606","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941606","url":null,"abstract":"Tip-tilt-z micro-positioning is crucial in wafer alignment. Due to the restrain of traditional manufacturing technique, it is hard to development compliant tip-tilt-z (CTTZ) mechanism in the form of single-piece monolithic structure. This paper presents the design, fabrication, and experimental tests of a CTTZ stage with monolithic spatial structure based on additive manufacturing (3D printing). The results verified the feasibility of developing complex compliant mechanism with spatial, compact, and monolithic structure, which could realize precision capability up to submicron and micro-radian using easy-access 3D-printing.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130810557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhiqiang Wang, G. Zhang, Yifan Liu, Shuze Geng, Donghuang Shi, Zhenghao Yang
{"title":"On Line Monitoring of Micro End Tool Wear Based on One-dmensional Fractal","authors":"Zhiqiang Wang, G. Zhang, Yifan Liu, Shuze Geng, Donghuang Shi, Zhenghao Yang","doi":"10.1109/3M-NANO56083.2022.9941621","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941621","url":null,"abstract":"Based on the theoretical derivation of one-dimensional fractal, a new method to realize on-line tool wear monitoring of micro end tool is proposed. First, several different wear conditions of micro end tool are chosen as comparison samples, which includes the wear rate of micro end tool is 0, 10, 20, 30, $i$ and tipping respectively. The vibration signals of all samples are collected in time domain, and the range $k$ of each wear status is obtained based on one-dimensional fractal. Secondly, the vibration status of tested tool is monitored and analyzed, and its one-dimensional fractal is extracted. Finally, comparing the one-dimensional fractal of the tested tool with the fractal dimension range $j$ of the comparison samples, the status of tested tool is detected. In order to verify the above monitoring method, a small triaxial vertical testing machine is used. The results show that the one-dimensional fractal of each monitored micro end tool falls within the range of fractal dimension corresponding to actual wear.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128262499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement of Corrosion Resistance of 7075 Aluminum Alloy by Micro Arc Oxidation after Hole Sealing Treatment","authors":"Jian Li, Yiquan Li, Qianqian Cai","doi":"10.1109/3M-NANO56083.2022.9941662","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941662","url":null,"abstract":"Aluminum alloys are widely used in aerospace and marine transportation industries because of their excellent properties. However, the aluminum oxide film on the surface of aluminum alloy in service is easy to be damaged by corrosive media, resulting in matrix corrosion cracking, which also hinders the wide application of aluminum alloy in more fields. In this paper, the PEO/SOT composite coating was prepared by plasma electrolytic oxidation (PEO) combined with surface oiling treatment (SOT). Oiling treatment can effectively cover the discharge channels and cracks on the PEO surface, so as to prevent corrosive ions from contacting through the coating and damaging the aluminum alloy matrix. The corrosion resistance of the composite coating was tested by electrochemical workstation. The results show that PEO/SOT composite coating has better corrosion resistance in corrosive environment than the substrate and PEO coating. This will help to expand the application of aluminum alloy in the field of higher requirements.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131012317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Linear Edge Fitting Method with Short Edge Correction","authors":"Fujun Wang, Xuteng Qin, Zhichen Huo, Dawei Zhang","doi":"10.1109/3M-NANO56083.2022.9941692","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941692","url":null,"abstract":"In this paper, a novel linear fitting method for micro vision is proposed, which can be utilized to accurately estimate the pose of components in micro-assembly. After obtaining the edge information through Canny edge detection, an improved least square method is put forward to fit the linear edge of small components, where a threshold is utilized to reduce the influence of outliers in point set. In order to improve the estimation accuracy, the fitted linear edge is iteratively corrected through the information of detected broken lines. Compared with conventional linear edge fitting methods, the experimental results indicated that proposed method could effectively reduce the confidence interval of the fitted line, which would be helpful to improve the accuracy of pose estimation in micro-assembly.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125857282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A New Type of High-frequency Piezoelectric Ultrasonic Transducer for Ultrasonically Assisted Manipulating, Machining, and Manufacturing","authors":"Xiaochen Liu, Hongjie Zhang, Rongxin Gao, Chuanhao Wu","doi":"10.1109/3M-NANO56083.2022.9941541","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941541","url":null,"abstract":"To improve the ultrasonic energy transfer efficiency of the high-frequency ultrasonic transducer used in micro-nano manipulating, manufacturing, and machining, a new type of ultrasonic transducer is designed in which a particular flexible mounting clamp is used. Different from the traditional mounting clamp that commonly adopts a rigid connecting arm, the newly proposed clamp introduces a parallelogram-compliant mechanism, which can provide the clamp a translation pair along the longitudinal direction of the transducer. The performance test results manifest that the newly proposed ultrasonic transducer has a good motion decoupling ability, and it also has a desired ultrasonic energy transfer efficiency, presenting a wide and bright application prospect.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123537134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xia Wang, Ye-Zi Li, Zuobin Wang, Ying Wang, M. Gao
{"title":"Effects of Buffer Solution and Concentration on AFM Imaging of DNA Molecules","authors":"Xia Wang, Ye-Zi Li, Zuobin Wang, Ying Wang, M. Gao","doi":"10.1109/3M-NANO56083.2022.9941673","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941673","url":null,"abstract":"The effects of buffer solution and concentration on atomic force microscope (AFM) imaging of DNA molecules were investigated. It was found that the buffer solution type and the DNA solution concentration affected the DNA topological conformations, and had distinct AFM imaging results. Moreover, DNA molecules diluted with the TE buffer under the DC electric field present stretching topological conformations. This study contributes to the understanding of formation factors of various DNA topological conformations and further promotes the application of DNA in nanotechnology and biology.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114411913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One-dimensional Bi2WO6/RGO Nanobelts Photocatalyst for Efficient Hydrogen Generation","authors":"F. Sun, Jing Zhao, Yunrui Xie, Danyan Xu, Wensheng Yu, Xiang-ting Dong","doi":"10.1109/3M-NANO56083.2022.9941358","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941358","url":null,"abstract":"Reduced graphene oxide (abbreviated as RGO) possesses a fantastic ability to accept and transfer electrons. Bi<inf>2</inf>WO<inf>6</inf> semiconductor is a superb visible light catalytic material, which not only owns narrow band gap, stable property, but also is non-toxic. Hence, Bi<inf>2</inf>WO<inf>6</inf>/RGO nanobelts are rationally devised and manufactured by combining electrospinning and calcination technique in this work. The hydrogen generation efficiency of Bi<inf>2</inf>WO<inf>6</inf>/2%RGO nanobelts reaches up to 492.22 µmol h<sup>-1</sup>, which is 2.52 times that of pure Bi<inf>2</inf>WO<inf>6</inf> nanobelts. The result can be ascribed to the addition of RGO, which can heighten the capture intensity of Bi<inf>2</inf>WO<inf>6</inf>/2%RGO nanobelts in the visible and ultraviolet light regions, and the conductivity of RGO can quickly transfer electrons, thus promoting the separation and transfer of charge carriers. Therefore, Bi<inf>2</inf>WO<inf>6</inf> nanobelts photocatalyst has a broad application prospect in the field of photocatalytic hydrogen generation.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126249802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design and Experiment on a Novel SMA Driven Micro-catheter for Active Navigation in Vascular Interventions","authors":"Chengyang Li, Kecai Xie, Zhongjing Ren, Peng Yan","doi":"10.1109/3M-NANO56083.2022.9941608","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941608","url":null,"abstract":"This paper presents a shape memory alloy (SMA) driven micro-catheter for active navigation in vascular interventions. SMA wires with microscale diameters and silicone rubber are employed for developing prototypes of such catheters. Selectively processed U shape SMA wires are biasedly embedded into silicone rubber to form the distal actuators with submillimeter diameters, which are characterized by infrared and CCD cameras. The transformation temperatures of SMA wires used for creation of distal actuator is proven to be approximately 35°C by the infrared imaging. The deflection angles of distal actuators are determined by the residual stress resulting from biased SMA wires and their shape memory effect. As a result, distal deflection within acute angles range is accomplished with actuators in submillimeter diameters. A micro-catheter (0.8 mm in diameter) with a distal actuator (0.5 mm in diameter) is mounted inside a vascular introducing sheath fixed on a 3D vascular model to experimentally validate the ability of proposed catheter for navigation.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132563805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Uniformity Ferroelectric MoS2 Nonvolatile Memory Array","authors":"Chunyang Li, Lu Li, Zhongyi Li, Fanqing Zhang, Lixin Dong, Jing Zhao","doi":"10.1109/3M-NANO56083.2022.9941686","DOIUrl":"https://doi.org/10.1109/3M-NANO56083.2022.9941686","url":null,"abstract":"Ferroelectric field effect transistor (FeFET) based on two-dimensional (2D) materials is centered great expectations for next-generation non-volatile memory devices owing to its excellent properties. In this paper, we fabricated monolayer $text{MoS}_{2}$ FeFET devices array through coupling ferroelectric P(VDF - TrFE) as the dielectric layer. The $text{MoS}_{2}$ FeFET device demonstrated excellent storage performance, including high on/off current ratios $boldsymbol{(> 10^{6})}$, a broad memory window (~15 V), long endurance (>200 cycles), and retention time (>1000 s). In additional, attributed to the chemical vapor deposition (CVD) synthesis of large-scale uniform Mos2,the devices array shows consistent characteristics, which suggest huge potential integrated circuit applications in the future.","PeriodicalId":370631,"journal":{"name":"2022 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133022008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}