环境科学与技术最新文献_第8页

Electrochemically Assisted Calcium Silicate Utilization for Phosphate Recovery

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-24 DOI: 10.1021/acs.est.5c00378

Ju Luo, Zhengshuo Zhan, Weiquan Li, Xin Zhang, Yang Lei

{"title":"Electrochemically Assisted Calcium Silicate Utilization for Phosphate Recovery","authors":"Ju Luo, Zhengshuo Zhan, Weiquan Li, Xin Zhang, Yang Lei","doi":"10.1021/acs.est.5c00378","DOIUrl":"https://doi.org/10.1021/acs.est.5c00378","url":null,"abstract":"Electrochemical pH-swing systems have demonstrated significant potential across diverse applications, including chemical production, carbon capture, and water treatment. However, conventional systems predominantly depend on costly ion exchange membranes, which are often plagued by fouling and scaling challenges. Here, we introduce an ingenious electrochemically assisted calcium silicate (EACS) system capable of achieving a rapid pH swing from 8.5 to 10 within 1 h through the in situ utilization of H+ and OH– ions, eliminating the need for membranes. The EACS system incorporates a novel 3D-printed porous basket holder designed to house calcium silicate particles and a rod-shaped Ru–Ir anode. Under closed-circuit conditions, the packed calcium silicate reacts with H+ generated at the anode, releasing Ca2+ into bulk solution, while OH– produced at the cathode accumulates, resulting in an elevated bulk pH. This mechanism enables the EACS system to achieve exceptional phosphorus recovery efficiency (88.4%–96.6%) from various waste streams, with energy consumption as low as 24.4 kWh kg P–1. Long-term continuous flow experiments demonstrate that periodic replacement of depleted silicate minerals sustains system efficiency and stability. Furthermore, comparative analysis reveals that while carbonate and silicate minerals are functionally viable, silicate minerals exhibit superior performance in removal kinetics, product purity, and reduced carbon emissions. Notably, the effluent from the EACS system, enriched with Ca2+ and characterized by a high pH, exhibits potential for direct air carbon capture. The proposed EACS system offers a transformative approach to environmental remediation and industrial applications, leveraging the fundamental principle of pH-swing to open new avenues for sustainable solutions.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"24 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enantiomer-Dependent Uptake of Chiral Nanoparticles in Macrophages Modulates the Inflammatory Response through the NF-κB Pathway

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-24 DOI: 10.1021/acs.est.4c12577

Jinghua Hao, Yijin Tian, Jie Tang, Nali Zhu, Zhigang Li, Lingxiangyu Li, Yawei Wang, Guibin Jiang

{"title":"Enantiomer-Dependent Uptake of Chiral Nanoparticles in Macrophages Modulates the Inflammatory Response through the NF-κB Pathway","authors":"Jinghua Hao, Yijin Tian, Jie Tang, Nali Zhu, Zhigang Li, Lingxiangyu Li, Yawei Wang, Guibin Jiang","doi":"10.1021/acs.est.4c12577","DOIUrl":"https://doi.org/10.1021/acs.est.4c12577","url":null,"abstract":"Infectious inflammation caused by pathogens or environmental pollutants remains a major global health issue. Therefore the development of novel strategies to efficaciously control infectious inflammation is urgently required. Nuclear factor-κB (NF-κB) as the central activator of pro-inflammatory genes plays a pivotal role in infectious inflammation. Here, nanoscale chirality was designed to modulate the inflammatory response through enantiomer-dependent blockade of the NF-κB signaling pathway. Chiral gold nanoparticles (AuNPs) with good cytocompatibility were prepared through a one-pot seedless method under wild conditions, showing efficacious alleviation of lipopolysaccharide (LPS)-induced inflammation in vitro and in vivo only by AuNPs with levorotatory chirality (L-AuNPs) rather than the dextrorotatory enantiomer (D-AuNPs). Mechanism investigation elucidated that lysosomal acidification of macrophages was inhibited through a high cellular uptake of L-AuNPs due to their weak interaction energy with cell membranes. Accordingly, the NF-κB rather than mitogen-activated protein kinase pathway was blocked by L-AuNPs through the selective inhibition of p65 phosphorylation, wherein the nuclear translocation of p65 was simultaneously depressed, so the secretion of pro-inflammatory mediators was reduced significantly. This study suggests that imparting chirality to nanoparticles can provide a novel protocol to efficaciously modulate health risks arising from infectious inflammation by improving the uptake of nanoparticles with anti-inflammatory activity.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"20 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occurrence, Removal, and Risk Assessment of Antimicrobials and Their Transformation Products in Effluent from Australian Wastewater Treatment Plants

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-24 DOI: 10.1021/acs.est.5c00425

Jinglong Li, Jake W. O’Brien, Ben J. Tscharke, Rory Verhagen, Chang He, Katja M. Shimko, Xueting Shao, Naixiang Zhai, Tobias Hulleman, Jochen F. Mueller, Kevin V. Thomas

{"title":"Occurrence, Removal, and Risk Assessment of Antimicrobials and Their Transformation Products in Effluent from Australian Wastewater Treatment Plants","authors":"Jinglong Li, Jake W. O’Brien, Ben J. Tscharke, Rory Verhagen, Chang He, Katja M. Shimko, Xueting Shao, Naixiang Zhai, Tobias Hulleman, Jochen F. Mueller, Kevin V. Thomas","doi":"10.1021/acs.est.5c00425","DOIUrl":"https://doi.org/10.1021/acs.est.5c00425","url":null,"abstract":"Despite Australia’s high antimicrobial use, their residues in wastewater and their impacts on receiving waters remain largely unknown. This study assessed the occurrence, removal, and risk for antimicrobial resistance (AMR) of 102 antimicrobial substances and selected transformation products (TPs) in wastewater effluent from 47 wastewater treatment plants (WWTPs) across Australia. Thirty-two antimicrobials and 13 TPs were detected, with 14 analytes occurring at >80% frequencies. Ampicillin, penicillin V, penicilloic V acid, fluconazole, and tazobactam M1 were observed with high median concentrations of >0.2 μg/L. Collectively, the WWTPs released 5.4 kg/day or 0.54 g/day/1000 inhabitants of antimicrobials/TPs into natural waters, with β-lactams, quinolones, nitroimidazoles/azoles, and sulfonamides comprising high volumes, which was correlated with the population’s socioeconomic statuses. Thirty-seven analytes were removed at rates >80% post-treatment, whereas quinolones, nitroimidazoles/azoles, lincosamides, and macrolide TPs were observed with poor removal efficiencies, which were affected by treatment processes and regional climate. Comparing measured concentrations with the predicted no-effect concentrations for AMR selection (PNECAMR), 7 antimicrobials exerted selection risk for resistant bacteria. Concerningly, ciprofloxacin posed medium/high risk in most of the assessed WWTPs. The accumulative effects of antimicrobial classes and certain TPs might further aggravate adverse impacts on AMR development. Our study provides insights into the presence and AMR implications of antimicrobials in treated wastewater, aiming to safeguard public health and ecosystems.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"34 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2

IF 10.8 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-23 DOI: 10.1021/acs.est.4c1473410.1021/acs.est.4c14734

Xupeng Liu, Yanbiao Shi*, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu*, Lizhi Zhang and Zhihui Ai*,

{"title":"Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2","authors":"Xupeng Liu, Yanbiao Shi*, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu*, Lizhi Zhang and Zhihui Ai*, ","doi":"10.1021/acs.est.4c1473410.1021/acs.est.4c14734","DOIUrl":"https://doi.org/10.1021/acs.est.4c14734https://doi.org/10.1021/acs.est.4c14734","url":null,"abstract":"Highly efficient molecular oxygen activation over transition metal oxides toward catalytic abatement of aromatic volatile organic compounds (AVOCs) is possible yet challenging due to the easily deactivated surface oxygen vacancy (VO). Herein, dynamic Mn–VO associates were crafted onto the Mn-incorporated CeO2 mesocrystal (Mn/meso-CeO2) surface with Mn substituting a Ce atom through an easy-to-handle precipitation strategy. Experiments and theoretical calculation demonstrated that the asymmetric surface Mn–O–Ce configuration induced electron delivery from the low-valent Mn to adjacent Ce, destabilizing the circumambient O atoms and facilitating the formation of dynamic Mn–VO associates. Compared to pristine meso-CeO2, the Mn/meso-CeO2 with dynamic Mn–VO associates could efficiently activate O2 into a superoxide radical and a peroxanion (O2•– and O22–) at higher reaction temperature (over 200 °C). Meanwhile, the O atom adjacent to Mn featuring substantially elevated Lewis acidity promoted the adsorption and activation of benzene. Consequently, the Mn/meso-CeO2 catalyst exhibited a superior catalytic oxidation reactivity (T90 = 215 °C) toward C6H6 combustion via a Langmuir–Hinshelwood mechanism. This work underlines the importance of rational design and regulation of catalytic sites over metal oxide surfaces for robust O2 activation and durable refractory AVOC combustion.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"59 12","pages":"6331–6340 6331–6340"},"PeriodicalIF":10.8,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143737673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-23 DOI: 10.1021/acs.est.4c14734

Xupeng Liu, Yanbiao Shi, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu, Lizhi Zhang, Zhihui Ai

{"title":"Dynamic Mn–VO Associates Boosted Molecular Oxygen Activation for Benzene Combustion on Mn-Doped Mesocrystalline CeO2","authors":"Xupeng Liu, Yanbiao Shi, Linghao Yu, Biao Zhou, Ziyue Chen, Furong Guo, Hao Li, Xiao Liu, Lizhi Zhang, Zhihui Ai","doi":"10.1021/acs.est.4c14734","DOIUrl":"https://doi.org/10.1021/acs.est.4c14734","url":null,"abstract":"Highly efficient molecular oxygen activation over transition metal oxides toward catalytic abatement of aromatic volatile organic compounds (AVOCs) is possible yet challenging due to the easily deactivated surface oxygen vacancy (VO). Herein, dynamic Mn–VO associates were crafted onto the Mn-incorporated CeO2 mesocrystal (Mn/meso-CeO2) surface with Mn substituting a Ce atom through an easy-to-handle precipitation strategy. Experiments and theoretical calculation demonstrated that the asymmetric surface Mn–O–Ce configuration induced electron delivery from the low-valent Mn to adjacent Ce, destabilizing the circumambient O atoms and facilitating the formation of dynamic Mn–VO associates. Compared to pristine meso-CeO2, the Mn/meso-CeO2 with dynamic Mn–VO associates could efficiently activate O2 into a superoxide radical and a peroxanion (O2•– and O22–) at higher reaction temperature (over 200 °C). Meanwhile, the O atom adjacent to Mn featuring substantially elevated Lewis acidity promoted the adsorption and activation of benzene. Consequently, the Mn/meso-CeO2 catalyst exhibited a superior catalytic oxidation reactivity (T90 = 215 °C) toward C6H6 combustion via a Langmuir–Hinshelwood mechanism. This work underlines the importance of rational design and regulation of catalytic sites over metal oxide surfaces for robust O2 activation and durable refractory AVOC combustion.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"54 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unexpected Room-Temperature Selective Catalytic Reduction of NOx with NH3 over Metal-Free Carbon-Based Catalysts

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-23 DOI: 10.1021/acs.est.4c14482

Rucheng Duan, Yu Fu, Zhuocan Li, Xin Wang, Meng Gao, Yunbo Yu, Guangzhi He, Hong He

引用次数: 0

Pattern Recognition-Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High-Throughput Screening and Experimental Verification

IF 10.8 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c1246610.1021/acs.est.4c12466

Jierong Chen, Boyang Li, Shaoqi Zuo, Kun Zhang, Jiayin Dai, Lili Chen* and Yanbin Zhao*,

{"title":"Pattern Recognition-Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High-Throughput Screening and Experimental Verification","authors":"Jierong Chen, Boyang Li, Shaoqi Zuo, Kun Zhang, Jiayin Dai, Lili Chen* and Yanbin Zhao*, ","doi":"10.1021/acs.est.4c1246610.1021/acs.est.4c12466","DOIUrl":"https://doi.org/10.1021/acs.est.4c12466https://doi.org/10.1021/acs.est.4c12466","url":null,"abstract":"Circadian rhythms regulate the timing of numerous biological functions in organisms. Besides well-known external stimuli like the light–dark cycle and temperature, circadian rhythms can also be modulated by environmental substances. However, this area remains largely underexplored. Here, we developed a robust Pattern Recognition-Driven Prediction Approach (PRD–PA) that enables the identification of circadian-disruptive compounds from large-scale zebrafish transcriptomic profiling. The approach utilizes a circadian gene panel consisting of over 270 Circadian-Indicating Genes (CIGs) with stable and robust periodicity and combines it with a predictive model, known as the Differential Gene Expression Values of an Individual Comparison Model (DGVICM), that can effectively predict internal circadian phases from transcriptomic samples. By analyzing 692 aggregated gene expression profiles across 40 environmental substances, several were identified as having significant circadian-disruptive potential. These include glucocorticoids (e.g., prednisone (PRE) and triamcinolone (TRI)), the antithyroid agent propylthiouracil (PTU), and the widely used UV filter benzophenone-3 (BP-3). Both glucocorticoids and PTU are well-documented disruptors of circadian rhythms, and BP-3’s circadian-disrupting properties were validated through experimental exposures. Moreover, BP-3 analogs, including 2,4-dihydroxybenzophenone (BP-1) and 2,2’-dihydroxy-4-methoxybenzophenone (BP-8), were also found to exhibit similar circadian-disruptive effects. Overall, the present findings demonstrated the reliability of the PRD–PA approach for circadian disruption screening and highlighted the presence of diverse circadian-disruptive substances in our environment.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"59 12","pages":"5960–5972 5960–5972"},"PeriodicalIF":10.8,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143737559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pattern Recognition-Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High-Throughput Screening and Experimental Verification 模式识别驱动的基因表达昼夜节律干扰化合物检测：高通量筛选与实验验证

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c12466

Jierong Chen, Boyang Li, Shaoqi Zuo, Kun Zhang, Jiayin Dai, Lili Chen, Yanbin Zhao

{"title":"Pattern Recognition-Driven Detection of Circadian-Disruptive Compounds from Gene Expressions: High-Throughput Screening and Experimental Verification","authors":"Jierong Chen, Boyang Li, Shaoqi Zuo, Kun Zhang, Jiayin Dai, Lili Chen, Yanbin Zhao","doi":"10.1021/acs.est.4c12466","DOIUrl":"https://doi.org/10.1021/acs.est.4c12466","url":null,"abstract":"Circadian rhythms regulate the timing of numerous biological functions in organisms. Besides well-known external stimuli like the light–dark cycle and temperature, circadian rhythms can also be modulated by environmental substances. However, this area remains largely underexplored. Here, we developed a robust Pattern Recognition-Driven Prediction Approach (PRD–PA) that enables the identification of circadian-disruptive compounds from large-scale zebrafish transcriptomic profiling. The approach utilizes a circadian gene panel consisting of over 270 Circadian-Indicating Genes (CIGs) with stable and robust periodicity and combines it with a predictive model, known as the Differential Gene Expression Values of an Individual Comparison Model (DGVICM), that can effectively predict internal circadian phases from transcriptomic samples. By analyzing 692 aggregated gene expression profiles across 40 environmental substances, several were identified as having significant circadian-disruptive potential. These include glucocorticoids (e.g., prednisone (PRE) and triamcinolone (TRI)), the antithyroid agent propylthiouracil (PTU), and the widely used UV filter benzophenone-3 (BP-3). Both glucocorticoids and PTU are well-documented disruptors of circadian rhythms, and BP-3’s circadian-disrupting properties were validated through experimental exposures. Moreover, BP-3 analogs, including 2,4-dihydroxybenzophenone (BP-1) and 2,2’-dihydroxy-4-methoxybenzophenone (BP-8), were also found to exhibit similar circadian-disruptive effects. Overall, the present findings demonstrated the reliability of the PRD–PA approach for circadian disruption screening and highlighted the presence of diverse circadian-disruptive substances in our environment.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"125 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches

IF 10.8 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c1127510.1021/acs.est.4c11275

Shuangjia Xue, Matthew J. Broerman, Gillian C. Goobie, Daniel J. Kass, James P. Fabisiak, Sally E. Wenzel and Seyed Mehdi Nouraie*,

{"title":"Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches","authors":"Shuangjia Xue, Matthew J. Broerman, Gillian C. Goobie, Daniel J. Kass, James P. Fabisiak, Sally E. Wenzel and Seyed Mehdi Nouraie*, ","doi":"10.1021/acs.est.4c1127510.1021/acs.est.4c11275","DOIUrl":"https://doi.org/10.1021/acs.est.4c11275https://doi.org/10.1021/acs.est.4c11275","url":null,"abstract":"Gaseous pollutants such as CO, NO2, O3, and SO2 are linked to adverse clinical outcomes in patients with fibrotic interstitial lung diseases (fILDs), particularly idiopathic pulmonary fibrosis. However, the effect of various exposure estimation methods on these findings remains unclear. This study aims to evaluate three spatial approaches─nearest neighbor (NN), inverse distance weighting (IDW), and Kriging─for estimating gaseous pollutant exposures and to assess how these methods affect health outcome estimates in fILD patients. A 10-fold cross-validation showed that Kriging had the lowest prediction error compared to NN and IDW, with RMSE for CO = 0.43 ppm (11%), O3 = 5.9 ppb (14%), SO2 = 2.7 ppb (12%), and NO2 = 7.6 ppb (9%), respectively. Kriging also excelled over other methods across wide spatial and temporal ranges, showing the highest spatial R2 for CO and O3 and the highest temporal R2 for SO2 and NO2. In a large cohort of patients with fILD, higher levels of CO, SO2, and NO2 exposure were associated with lower pulmonary function. The magnitude of association and its precision were higher in SO2 and CO estimated by the Kriging method. This study underscores Kriging as a robust method for estimating gaseous pollutant levels and offers valuable insights for future epidemiological studies.Evaluating spatial methods for estimating gaseous pollutant exposures and their impact on health outcomes in fibrotic interstitial lung disease.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"59 12","pages":"5936–5945 5936–5945"},"PeriodicalIF":10.8,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.est.4c11275","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143737558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-03-22 DOI: 10.1021/acs.est.4c11275

Shuangjia Xue, Matthew J. Broerman, Gillian C. Goobie, Daniel J. Kass, James P. Fabisiak, Sally E. Wenzel, Seyed Mehdi Nouraie

{"title":"Gaseous Air Pollutants and Lung Function in Fibrotic Interstitial Lung Disease (fILD): Evaluation of Different Spatial Analysis Approaches","authors":"Shuangjia Xue, Matthew J. Broerman, Gillian C. Goobie, Daniel J. Kass, James P. Fabisiak, Sally E. Wenzel, Seyed Mehdi Nouraie","doi":"10.1021/acs.est.4c11275","DOIUrl":"https://doi.org/10.1021/acs.est.4c11275","url":null,"abstract":"Gaseous pollutants such as CO, NO2, O3, and SO2 are linked to adverse clinical outcomes in patients with fibrotic interstitial lung diseases (fILDs), particularly idiopathic pulmonary fibrosis. However, the effect of various exposure estimation methods on these findings remains unclear. This study aims to evaluate three spatial approaches─nearest neighbor (NN), inverse distance weighting (IDW), and Kriging─for estimating gaseous pollutant exposures and to assess how these methods affect health outcome estimates in fILD patients. A 10-fold cross-validation showed that Kriging had the lowest prediction error compared to NN and IDW, with RMSE for CO = 0.43 ppm (11%), O3 = 5.9 ppb (14%), SO2 = 2.7 ppb (12%), and NO2 = 7.6 ppb (9%), respectively. Kriging also excelled over other methods across wide spatial and temporal ranges, showing the highest spatial R2 for CO and O3 and the highest temporal R2 for SO2 and NO2. In a large cohort of patients with fILD, higher levels of CO, SO2, and NO2 exposure were associated with lower pulmonary function. The magnitude of association and its precision were higher in SO2 and CO estimated by the Kriging method. This study underscores Kriging as a robust method for estimating gaseous pollutant levels and offers valuable insights for future epidemiological studies.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"16 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0