环境科学与技术最新文献_第10页

Mild Tuning of the Microbial Habitat via Titanium-Based Pre-coagulation Mitigates Reverse Osmosis Membrane Fouling. 通过钛基预混凝轻度调节微生物栖息地减轻反渗透膜污染。

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-20 DOI: 10.1021/acs.est.5c03970

Ruonan Gao,Haojie Ding,Mengyao Gu,Chao Chen,Yajun Sun,Yuchen Xin,Shuai Liang,Xia Huang

{"title":"Mild Tuning of the Microbial Habitat via Titanium-Based Pre-coagulation Mitigates Reverse Osmosis Membrane Fouling.","authors":"Ruonan Gao,Haojie Ding,Mengyao Gu,Chao Chen,Yajun Sun,Yuchen Xin,Shuai Liang,Xia Huang","doi":"10.1021/acs.est.5c03970","DOIUrl":"https://doi.org/10.1021/acs.est.5c03970","url":null,"abstract":"Membrane fouling remains a persistent challenge in reverse osmosis (RO) systems. Devising effective strategies to mitigate membrane fouling has become crucial for sustainable water treatment. Here, we propose a titanium-based pre-coagulation strategy for RO fouling mitigation through regulation of the microbial habitat in RO feed. The pre-coagulation performance of Ti(SO4)2 for desulfurization wastewater and the subsequent RO fouling mechanism were systematically investigated. Our findings revealed that the Ti pre-coagulation induced an acidized environment, maintained a balance between organic and inorganic depositions, and fostered a beneficial microbial community that resisted rapid fouling. The 20 day RO operations in different pre-coagulation scenarios (Ti, Al, and Ctrl) showed that the Ti group membranes maintained the highest normalized flux at 57.15%, outperforming the Ctrl and Al groups by 7.92% and 15.16%, respectively. Microbial community analyses, including taxonomic profiling and metagenomic analysis, demonstrated that Ti-based pre-coagulation reduced the dominance of extracellular polymeric substance (EPS)-secreting genera, such as Sphingopyxis, while promoting Terrimonas and Paenarthrobacter, with acid-tolerance traits and reduced EPS production. This shift mitigated biofouling by enhancing microbial balance and limiting biofilm formation. These results underscored the potential of the Ti pre-coagulation-based microbial habitat tuning strategy in enhancing RO system sustainability, offering a practical solution for improving industrial wastewater treatment.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"97 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Achieving Nearly 100% Targeted Conversion of NO to NO2 through Cooperative Activation of Lattice Oxygen and Molecular Oxygen on Dual-Defect LaMnO3. 通过晶格氧和分子氧在双缺陷LaMnO3上的协同活化，实现了近100%的NO到NO2的靶向转化。

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-20 DOI: 10.1021/acs.est.5c03218

Zhen Qian,Bo Yuan,Shiwei Sheng,Fei Lai,Jianjun Chen,Jinxing Mi,Zhao Ma,Runlong Hao,Junhua Li,Lidong Wang

{"title":"Achieving Nearly 100% Targeted Conversion of NO to NO2 through Cooperative Activation of Lattice Oxygen and Molecular Oxygen on Dual-Defect LaMnO3.","authors":"Zhen Qian,Bo Yuan,Shiwei Sheng,Fei Lai,Jianjun Chen,Jinxing Mi,Zhao Ma,Runlong Hao,Junhua Li,Lidong Wang","doi":"10.1021/acs.est.5c03218","DOIUrl":"https://doi.org/10.1021/acs.est.5c03218","url":null,"abstract":"Inhibiting the deposition of N species on the catalyst surface for the targeted oxidation of NO to NO2 is still a great challenge. Herein, a La and O dual-defective LaMnO3 (2U-L0.8MO) perovskite was fabricated using a urea-nonstoichiometric comodulation strategy, which achieved 97.6% NO oxidation efficiency at 210 °C and 300,000 h-1, and was also capable of nearly 100% targeted oxidation of NO to NO2, as well as exhibited excellent stability and recyclability. Characterizations and theoretical calculations unveiled that the urea-nonstoichiometric modulation method optimized the specific surface area and geometrical structure of perovskite, promoted the formation of La defects and oxygen vacancies (OVs), enhanced lattice oxygen activation and migration, and also facilitated the coadsorption of NO and O2 and increased the d-band center of the perovskite. The synergistic activation of lattice oxygen and molecular oxygen along with the low-temperature oxidation mechanisms of NO was finally revealed: the comodulation strategy caused stretching and distortion of the 2U-L0.8MO lattice, making its lattice oxygen susceptible to activation, thereby oxidizing adsorbed NO to NO2 and simultaneously generating OVs. Afterward, O2 would be captured by the abundant OVs on the 2U-L0.8MO surface and converted to superoxide O2-, which could not only directly oxidize NO but also transform into single 1O2 on the adjacent Mn4+ site for the targeted oxidation of NO. This work realizes the coactivation of O2 and lattice oxygen and also extends the understanding of the low-temperature-targeted oxidation of NO.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"45 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Marginal Asthma Prevalence from NOx Emissions (MANE): A Model to Predict Pediatric Asthma Burden from Emissions of Nitrogen Oxides. 氮氧化物排放引起的边际哮喘患病率（MANE）：一个预测氮氧化物排放引起的儿童哮喘负担的模型。

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.4c09012

Brian M Gentry,Allen L Robinson,Peter J Adams

{"title":"Marginal Asthma Prevalence from NOx Emissions (MANE): A Model to Predict Pediatric Asthma Burden from Emissions of Nitrogen Oxides.","authors":"Brian M Gentry,Allen L Robinson,Peter J Adams","doi":"10.1021/acs.est.4c09012","DOIUrl":"https://doi.org/10.1021/acs.est.4c09012","url":null,"abstract":"Pediatric asthma affects roughly 1 in 15 children in the U.S., with significantly higher rates in Black children. Exposure to NO2 contributes to asthma development, but quantitative analysis of pediatric asthma burden attributable to NOx emissions is rarely performed due to a lack of suitable models. This paper describes a new model, Marginal Asthma prevalence from NOx Emissions (MANE), which assesses the pediatric asthma burden from NOx emissions and its distribution across race/ethnicities. We find that emissions in more densely populated areas cause a larger number of pediatric asthma cases and tend to disproportionately impact minority communities. We applied our model to assess the pediatric asthma burden from sources of NOx, finding that diesel heavy-duty vehicles are responsible for approximately 4% of all pediatric asthma cases in the U.S. Additionally, we find that all source sectors considered disproportionately impact children of color, with 65-100% higher per-capita asthma rates in Black children compared to white non-Hispanic children. Finally, we find that emissions in a limited number of urban areas are responsible for a large share of asthma cases, suggesting that local, targeted restrictions on NOx emissions may provide great public health benefit nationally.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"53 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wildfires in Alaskan Boreal Forests Release Elevated Levels of Polyaromatic Hydrocarbon 阿拉斯加北方森林的野火释放出高浓度的多芳香烃

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.4c09278

Md Ibnul Hasan, Nibedita Sinha, Busra Sonmez Baghirzade, Sarthak Karki, Upasana Arora, Mary Jo Kirisits, Srijan Aggarwal, Navid B. Saleh, Subhabrata Dev

{"title":"Wildfires in Alaskan Boreal Forests Release Elevated Levels of Polyaromatic Hydrocarbon","authors":"Md Ibnul Hasan, Nibedita Sinha, Busra Sonmez Baghirzade, Sarthak Karki, Upasana Arora, Mary Jo Kirisits, Srijan Aggarwal, Navid B. Saleh, Subhabrata Dev","doi":"10.1021/acs.est.4c09278","DOIUrl":"https://doi.org/10.1021/acs.est.4c09278","url":null,"abstract":"Despite the increasing intensity of wildfires in Alaska’s extensive and flammable boreal forests, there remains a critical gap in understanding their environmental impacts, particularly on water systems. This study examines water, soil, sediment, and ash samples from the North and Middle Fork regions of the upper Chena River watershed, which faces recurring annual wildfires. Polyaromatic hydrocarbon (∑PAH) concentrations range from 41.1 to 1455.3 ng/L in water and 14.5 to 63.2 μg/kg in sediments, topsoil, and ash. Water primarily contains phenanthrene and trace levels of pyrene and fluorene, while solid samples exhibit elevated levels of naphthalene and phenanthrene, along with trace amounts of acenaphthene, anthracene, and fluorene. Runoff and terrain slope patterns derived from topographical analyses of the Chena River watershed might explain some of these elevated PAH levels, which surpass those found in other wildfire-affected watersheds worldwide. These findings underscore the risks to aquatic ecosystems, as PAHs are toxic, bioaccumulative, and can lead to the formation of harmful disinfection byproducts. Thus, the increasing frequency of wildfires in Alaska poses a significant threat to local communities relying on wildfire-impacted freshwater for fishing and drinking.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"54 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Oxygenation Resuspension on DOM Composition and Its Role in Reducing Dissolved Manganese in Drinking Water Reservoirs. 氧合再悬浮对饮用水中DOM组成的影响及其对溶解锰的还原作用

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.5c00235

Ming Su,Weiwei Li,Jiao Fang,Tengxin Cao,Yufan Ai,Changwei Lü,Jinbo Zhao,Ziyi Yang,Min Yang

{"title":"Effects of Oxygenation Resuspension on DOM Composition and Its Role in Reducing Dissolved Manganese in Drinking Water Reservoirs.","authors":"Ming Su,Weiwei Li,Jiao Fang,Tengxin Cao,Yufan Ai,Changwei Lü,Jinbo Zhao,Ziyi Yang,Min Yang","doi":"10.1021/acs.est.5c00235","DOIUrl":"https://doi.org/10.1021/acs.est.5c00235","url":null,"abstract":"Anaerobic conditions in source water sediments are a key driver of manganese (Mn) release in drinking water systems. Enhancing sediment oxidation can inhibit Mn release, but the mechanisms of Mn speciation under varying oxidative conditions remain unclear. This study examined sediment exposure to oxygenated water layers at controlled dissolved oxygen levels (0, 2, 5, 7 mg L-1) through laboratory simulations. Results showed Mn release is negatively correlated with DO (R2 = 0.93, p = 0.034), with oxygen driving reactions between dissolved organic matter (C2 and C3 components) and forming functional groups (-OH, -COOH) that remove Mn through adsorption or complexation (C2: R2 = 0.57, p < 0.001; C3: R2 = 0.53, p < 0.001). Field studies in six reservoirs identified operational thresholds for sediment resuspension to mitigate Mn risks (compensation threshold: 17.4 μg L-1; risk threshold: China: 95.5 μg L-1; WHO: 70.8 μg L-1). These findings clarify Mn-organic matter interactions and can provide practical guidance for Mn and algae removal in source water systems.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"32 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiological Stress Response to Sulfide Exposure of Freshwater Anaerobic Methanotrophic Archaea. 淡水厌氧甲烷营养古菌对硫化物暴露的生理应激反应。

IF 10.8 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.4c12489

Maider J Echeveste Medrano, Sarah Lee, Rob de Graaf, B Conall Holohan, Irene Sánchez-Andrea, Mike S M Jetten, Cornelia U Welte

{"title":"Physiological Stress Response to Sulfide Exposure of Freshwater Anaerobic Methanotrophic Archaea.","authors":"Maider J Echeveste Medrano, Sarah Lee, Rob de Graaf, B Conall Holohan, Irene Sánchez-Andrea, Mike S M Jetten, Cornelia U Welte","doi":"10.1021/acs.est.4c12489","DOIUrl":"https://doi.org/10.1021/acs.est.4c12489","url":null,"abstract":"Freshwater wetlands and coastal sediments are becoming hotspots for the emission of the greenhouse gas methane. Eutrophication-induced deposition of organic matter leads to elevated methanogenesis and sulfate reduction, thereby increasing the concentrations of methane and toxic sulfide, respectively. However, the effects of sulfide stress on the anaerobic methanotrophic biofilter have not been well explored. Here, we show how an enrichment culture dominated by the freshwater anaerobic methane-oxidizing archaeon \"Candidatus (Ca.) Methanoperedens\" responds to short-term and long-term exposure to sulfide in a bioreactor. The methane-oxidizing activity decreased to 45% and 20% but partially recovered to 70% and 30% within 5 days after short- and long-term sulfide exposure, respectively. Metagenomics indicated that \"Ca. Methanoperedens\" remained dominant in the enrichment throughout the entire experiment. The first short-term sulfide pulse led to increased expression of genes encoding for sulfide detoxification by low abundant community members, whereas long-term exposure resulted in upregulation of \"Ca. Methanoperedens\" genes encoding sulfite reductases of group III (Dsr-LP). \"Ca. Methanoperedens\" consumed polyhydroxyalkanoates during long-term sulfide exposure, possibly to aid in stress adaptation. Together, these results provide a valuable baseline for understanding fundamental ecophysiological adaptations to methane cycling in sulfate- and nitrate-rich aquatic ecosystems.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":" ","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon Balance of China-Made Wood Products Assessed Using a Trade-Linked Approach. 基于贸易关联方法的中国木制品碳平衡评估

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.4c09208

Xiaobiao Zhang,Jiaxin Chen,Manfred Lenzen,Pau Brunet-Navarro,Ana Cláudia Dias,Shuai Shao,Gang Liu,Zhi Cao,Wen Hu,Fei Lu,Hongqiang Yang,Zhiyun Ouyang

{"title":"Carbon Balance of China-Made Wood Products Assessed Using a Trade-Linked Approach.","authors":"Xiaobiao Zhang,Jiaxin Chen,Manfred Lenzen,Pau Brunet-Navarro,Ana Cláudia Dias,Shuai Shao,Gang Liu,Zhi Cao,Wen Hu,Fei Lu,Hongqiang Yang,Zhiyun Ouyang","doi":"10.1021/acs.est.4c09208","DOIUrl":"https://doi.org/10.1021/acs.est.4c09208","url":null,"abstract":"Harvested wood products (HWPs) contribute to forestry carbon removal and, therefore, to climate change mitigation. However, the complex international trade of raw wood materials and HWPs and the associated biogenic carbon conversion along the global supply chain are not properly accounted for in the existing HWP carbon accounting schemes, precluding effective climate policy design. To address the gap, we developed a generalizable Trade-Linked Approach to account for trade and the associated carbon stocks and emissions. In the case study for China-made HWPs in 1990-2020, trade partners supplied 22% (1425 MtCO2e, or 389 MtC) of raw materials and consumed 13% (691 MtCO2e, or 189 MtC) of the HWPs, with the latter double that of the FAOSTAT statistics that were used in the existing studies. In the same period, the trade partners contributed 13% (570 MtCO2e) of the total HWP carbon stocks. The HWPs consumed overseas provided a 43 MtCO2e yr-1 carbon sink (15% of the total) from 2016 to 2020, which is close to the \"forest and land use carbon credits\" transacted in global voluntary carbon markets in 2020. In addition to adequately allocating carbon removals to each country, we appeal for a global HWP-associated carbon payment scheme to incentivize HWP-based mitigation activities along the supply chain.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"54 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined Analysis of Network Toxicology and Multiomics Revealed the Potential Mechanism of 6PPDQ-Induced Hepatotoxicity in Mice. 网络毒理学和多组学联合分析揭示6ppdq诱导小鼠肝毒性的潜在机制。

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.5c03906

Bo Li,Chenchen Xu,Duo Zhang,Siwen Wang,Jingwen Xu,Bang Xiao,Yue Feng,Hong-Yu Fu,Xiaoxiao Chen,Ziwei Zhang

{"title":"Combined Analysis of Network Toxicology and Multiomics Revealed the Potential Mechanism of 6PPDQ-Induced Hepatotoxicity in Mice.","authors":"Bo Li,Chenchen Xu,Duo Zhang,Siwen Wang,Jingwen Xu,Bang Xiao,Yue Feng,Hong-Yu Fu,Xiaoxiao Chen,Ziwei Zhang","doi":"10.1021/acs.est.5c03906","DOIUrl":"https://doi.org/10.1021/acs.est.5c03906","url":null,"abstract":"6PPDQ, a rubber tire-derived environmental pollutant, exhibits significant hepatotoxicity. However, its hepatotoxic mechanisms remain insufficiently studied and systematically evaluated. This study integrated network toxicology, transcriptomics, and metabolomics to investigate its toxicity mechanisms. ADMETlab 3.0 was used to predict physicochemical properties and multiorgan toxicity. The targets related to 6PPDQ and liver injury were obtained from public databases, and a protein-protein interaction (PPI) network was constructed to identify key targets. Meanwhile, molecular docking was performed to assess 6PPDQ's binding affinity to core proteins. Transcriptomics and differential gene expression analysis were performed on the livers of Kunming mice exposed to 4 mg/kg 6PPDQ to explore transcriptomic alterations, while metabolomic profiling identified disrupted metabolic pathways. Network toxicology results reveal that 6PPDQ primarily induces hepatotoxicity through apoptosis, inflammation, and lipid metabolic disturbances. Key targets, including P53, Mapk1, Mapk14, Casp8, Traf6, Ripk1, and Tnf, are identified, with strong binding affinities suggesting direct interactions. Transcriptomic and metabolomic analyses further confirms disruptions in TNF, NF-kappa B, oxidative phosphorylation, autophagy pathways, and glycerolipid metabolism. Overall, this study provides a comprehensive mechanistic framework for 6PPDQ-induced liver injury in mice and provides a new perspective for subsequent studies on the mechanism of 6PPDQ hepatotoxicity.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"14 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Temporal Response Surface: A Novel Method for the Assessment of Delayed and Time-Cumulative Aquatic Ecosystem Risk 时间响应面：一种评估延迟和时间累积水生生态系统风险的新方法

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-19 DOI: 10.1021/acs.est.4c14331

Cath A. Neelamraju, Reinier M. Mann, Michael St J. Warne, Francisco Sanchez-Bayo, Ryan D.R. Turner

{"title":"The Temporal Response Surface: A Novel Method for the Assessment of Delayed and Time-Cumulative Aquatic Ecosystem Risk","authors":"Cath A. Neelamraju, Reinier M. Mann, Michael St J. Warne, Francisco Sanchez-Bayo, Ryan D.R. Turner","doi":"10.1021/acs.est.4c14331","DOIUrl":"https://doi.org/10.1021/acs.est.4c14331","url":null,"abstract":"In Australia, pesticide risk assessments in aquatic environments typically compare measured water concentrations to relevant ecosystem protection guidelines based on species sensitivity distributions (SSDs). These guidelines estimate concentrations that are protective against long-term (chronic) exposure but do not consider extended exposure to chemicals with cumulative toxicity, such as neonicotinoid insecticides. The Australian and New Zealand Guidelines caution against the application of default acute to chronic ratios (ACRs) for such chemicals but lack suitable alternatives. Addressing this gap, we introduce the Temporal Response Surface (TRS) method that incorporates exposure duration into SSDs via taxa-specific regression relationships. The TRS considers both toxicity and exposure duration, setting meaningful guidelines for aquatic ecosystem protection and facilitating probabilistic risk assessments. Applied to imidacloprid, concentrations that are protective of 99, 95, 90, and 80% of the ecosystem (PC99, PC95, PC90, and PC80, respectively) drop quickly within the first 30 days of continuous exposure, then progressively decline over longer exposure periods. This suggests that previous risk assessments may have underestimated the toxic effects of prolonged or repeated imidacloprid exposure. The TRS method offers a holistic solution, addressing policy and risk assessment gaps for chemicals with delayed or cumulative toxicity, further enhancing aquatic ecosystem protection in Australia and internationally.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"41 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avian-Specific Evidence for an Estrogen Receptor Agonism Adverse Outcome Pathway Based on Chicken Embryos and LMH 3D Spheroids Exposed to Ethinylestradiol and Bisphenol A. 暴露于雌酮和双酚A的鸡胚胎和LMH 3D球体雌激素受体激动作用不良结局通路的鸟类特异性证据。

IF 9.028 1区环境科学与生态学

环境科学与技术 Pub Date : 2025-05-18 DOI: 10.1021/acs.est.4c10887

Tasnia Sharin,Kim L Williams,Rudolf W Mueller,Doug Crump,Jason M O'Brien

{"title":"Avian-Specific Evidence for an Estrogen Receptor Agonism Adverse Outcome Pathway Based on Chicken Embryos and LMH 3D Spheroids Exposed to Ethinylestradiol and Bisphenol A.","authors":"Tasnia Sharin,Kim L Williams,Rudolf W Mueller,Doug Crump,Jason M O'Brien","doi":"10.1021/acs.est.4c10887","DOIUrl":"https://doi.org/10.1021/acs.est.4c10887","url":null,"abstract":"Several adverse outcome pathways (AOPs) describe the effects of endocrine disrupting compounds on estrogen signaling. Substantial data support an AOP related to estrogen receptor (ER) antagonism, leading to decreased fecundity in fish. In this study, data were generated for an ER agonism AOP leading to reduced fecundity in avian species (AOP537). Chicken embryos and the chicken leghorn male hepatoma cell line, LMH, were used to elucidate key events associated with estrogen signaling following exposure to 17α-ethinylestradiol (EE2) and bisphenol A (BPA). Embryos were exposed via egg injection. Viability and hepatic estrogen-responsive gene expression data were collected at midincubation (embryonic day [ED] 11). Changes in plasma vitellogenin (VTG), gonad morphology and growth were evaluated prior to pipping (ED20). Both chemicals dysregulated estrogen-responsive genes in hepatic tissue and increased plasma VTG concentrations. In LMH spheroids, EE2 and BPA altered estrogen-responsive genes and VTG concentrations at 24 and 48 h, respectively. Gonadal histology revealed oocyte-type cells and loss of testicular cords in male embryos exposed to EE2 and BPA. Overall, EE2 and BPA upregulated VTG mRNA expression, increased plasma VTG, and caused impairments in gonadal development. These results contribute avian-specific evidence to support an endocrine disruption AOP describing the relationship between disrupted VTG synthesis and impaired reproduction.","PeriodicalId":36,"journal":{"name":"环境科学与技术","volume":"61 1","pages":""},"PeriodicalIF":9.028,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0