BDJ Open最新文献

{"title":"Infection prevention and control practices among dental healthcare professionals in Somaliland: a multicity cross-sectional study.","authors":"Dek Kahin Yosef, Ayan Abdirizaq Hussein","doi":"10.1038/s41405-026-00483-4","DOIUrl":"10.1038/s41405-026-00483-4","url":null,"abstract":"<p><strong>Background: </strong>Dental healthcare personnel are exposed to blood, saliva, sharp instruments, and procedure-generated aerosols. Evidence on infection prevention and control (IPC) practices in Somaliland dental services is limited. This study assessed IPC practices and examined factors associated with the IPC practice score among dental healthcare professionals.</p><p><strong>Methods: </strong>A facility-based cross-sectional survey included 180 dental healthcare professionals from accessible public and private dental facilities in four Somaliland study areas. A structured self-administered questionnaire measured professional characteristics, IPC systems, vaccination, knowledge, attitudes, reported practices, occupational exposure, and barriers. Five knowledge items produced a score of 0-5. Seven frequency-based practice items were scored from 0 to 4 and summed to a score of 0-28; scores of at least 75% were classified as good practice. Univariable and multivariable linear regression with robust standard errors estimated associations with the continuous practice score. Fractional-logit and workload-restriction analyses assessed sensitivity.</p><p><strong>Results: </strong>Participants had a mean age of 27.2 years (SD 3.5); 64.4% were male and 74.4% were general dentists. The mean knowledge score was 3.20/5 (SD 1.00), and 33.9% had good knowledge. The mean practice score was 25.73/28 (SD 2.34), and 174/180 (96.7%) reached the prespecified 75% threshold. Always performing hand hygiene before and after each patient was reported by 81.1%; always using and changing gloves between patients was reported by 96.7%. Only 21.7% selected an N95 respirator for aerosol procedures, and 22.2% reported biological-indicator sterilization monitoring. In adjusted analysis, no recent IPC training (adjusted beta -1.44, 95% CI -2.47 to -0.41), PPE supplies available only sometimes (-1.38, 95% CI -2.42 to -0.34) or rarely (-4.99, 95% CI -7.02 to -2.96), and treating 10-19 rather than fewer than 10 patients daily (-0.89, 95% CI -1.67 to -0.11) were associated with lower practice scores. Sensitivity analyses produced materially similar patterns.</p><p><strong>Conclusions: </strong>Reported compliance with several routine practices was high, but important gaps remained in respiratory protection, sterilization monitoring, occupational vaccination, post-exposure systems, and reliable PPE supply. Because the total eligible population and response rate were unknown, and practices were self-reported, the magnitude and generalizability of these estimates remain uncertain. Facility-level IPC programs should prioritize dependable supplies, recurrent competency-based training, sterilization quality assurance, vaccination, and post-exposure management.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149064970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatic posture analysis of dentists in real-world clinical settings via a composite OpenPose keypoint detection-geometric approach: a pilot study.","authors":"Jie Xu, Ji Jie, Bo Zeng, Shenghui Liu, Weicai Jiang, Youran Fang, Weini Xin","doi":"10.1038/s41405-026-00487-0","DOIUrl":"10.1038/s41405-026-00487-0","url":null,"abstract":"<p><strong>Objective: </strong>This small pilot/internal feasibility study aimed to develop and preliminarily evaluate an automated composite OpenPose keypoint detection-geometric method for analyzing dentists' sitting postures in real-world clinical settings.</p><p><strong>Methods: </strong>A questionnaire survey of 126 dental professionals identified high-risk musculoskeletal regions. Based on expert consensus and ergonomic guidelines, posture parameters and their normal reference ranges were defined. Five dentists were video-recorded during routine scaling procedures, and 30 representative image frames were selected. A custom algorithm was developed to automatically compute head-neck flexion angle, trunk flexion angle, knee joint angles, and a composite score quantifying deviations from ergonomic norms using OpenPose-derived keypoints. These automated measurements were compared with manually annotated ground-truth measurements using mean absolute error (MAE) and mean absolute percentage error (MAPE).</p><p><strong>Results: </strong>The automated method demonstrated low mean absolute and relative differences with the manual reference measurements. The MAEs were 0.74° for head-neck flexion angle, 0.26° for trunk flexion angle, and 0.67° for knee joint angle-all well below the clinically acceptable threshold of 5°. The corresponding MAPEs of these three measurements were 1.11%, 2.94%, and 0.57%, respectively. And the composite score achieved an MAE of 0.84 and a MAPE of 1.96%.</p><p><strong>Conclusion: </strong>This study developed three posture parameters and a composite score as quantitative indicators of dentists' postures in real-world clinical settings. It also developed a geometric algorithm based on two-dimensional keypoint detection to automatically extract these scores, achieving relatively high accuracy compared with manual reference measurements. Following further refinement and thorough validation, the composite score and geometric algorithm have the potential to be deployed in clinical settings to monitor dentists' postures in real time and provide immediate alerts when poor posture is detected, thereby helping to improve ergonomic practices.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current status, evidence maturity, and translational readiness of artificial intelligence in dentistry: a bibliometric and thematic analysis.","authors":"Iman Nabilah Abd Rahim, Nashuha Omar, Norazreen Zakaria, Rahayu Zulkapli, Rohana Ahmad, Nur Hafizah Kamar Affendi, Norhasmira Mohammad, Marshima Mohd Rosli, Ilham Wan Mokhtar, Ain Ashraf Rizwal, Mohd Yusmiaidil Putera Mohd Yusof","doi":"10.1038/s41405-026-00478-1","DOIUrl":"10.1038/s41405-026-00478-1","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) has rapidly expanded across dental research, particularly in imaging-based diagnostics and digital workflows. Despite the accelerating publication growth, the structural evolution, thematic maturity, and translational readiness of AI in dentistry remain insufficiently synthesised.</p><p><strong>Methods: </strong>Publications related to AI in dentistry between 2015 and 2025 were retrieved from the Scopus database. Bibliometric analyses were conducted to examine annual outputs, countries, institutions, authors, journals, and keyword co-occurrence patterns. Network visualisation and clustering were performed using VOSviewer to identify research hotspots and thematic evolution. Selected evidence syntheses were evaluated using the Risk of Bias in Systematic Reviews (ROBIS) tool to assess methodological robustness and evidence maturity.</p><p><strong>Results: </strong>A total of 3665 publications were included. Research output demonstrated marked post-2019 acceleration, with deep learning and convolutional neural networks dominating the methodological landscape. The United States, China, and India were the most productive countries, while a core group of highly connected authors shaped collaborative structures. Keyword clustering revealed a clear thematic progression from algorithmic development and image segmentation toward diagnostic imaging applications, digital dentistry integration, and workflow optimisation. Among the 75 systematic reviews evaluated using ROBIS, 50 (66.7%) demonstrated an unclear overall risk of bias, 24 (32.0%) showed a low risk of bias, and only one (1.3%) was classified as high risk, indicating that methodological transparency and evidence synthesis have not progressed at the same pace as technological innovation.</p><p><strong>Conclusion: </strong>AI research in dentistry is experiencing rapid expansion and increasing international collaboration, and continuous thematic evolution towards clinically relevant applications. However, the ROBIS assessment indicates that improvements in methodological quality and reporting transparency of evidence syntheses are still required to strengthen confidence in the current evidence base. Future studies should prioritise multicentre validation, standardised evaluation frameworks, rigorous systematic reviews, and clinically meaningful outcome measures to facilitate the safe and effective translation of AI into routine dental practice.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149031640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 10-year evolution of a dental undergraduate 'Blended Learning' suturing programme.","authors":"Anna Dargue, Richa Arya, Tamara Khayatt","doi":"10.1038/s41405-026-00467-4","DOIUrl":"10.1038/s41405-026-00467-4","url":null,"abstract":"<p><strong>Introduction: </strong>Undergraduate dental students in the United Kingdom must be competent in intra-oral suturing before graduating. In 2014, a blended learning programme was introduced to enhance suturing teaching.</p><p><strong>Methods: </strong>Students first completed an online suturing tutorial. This was designed for them to review at their own pace, promoted self-directed learning and provided a degree of standardisation in theoretical knowledge. Subsequently, students attended a practical session using simulation aids, translating theory into practice and promoting deeper learning. Staff offered guidance in these sessions and students undertook peer evaluation. Mixed methods action research was used iteratively to study student evaluation from the programme over a decade.</p><p><strong>Results: </strong>745 undergraduate student responses were evaluated. These influenced adaptations to the programme such as introducing teaching earlier in the undergraduate programme, mounting suturing foam pads into a phantom head, and extending the duration of the session. 2024 results demonstrated 98% of students felt competent to handle the suture needle, and 95% felt prepared to apply these skills on a patient after completing the programme.</p><p><strong>Conclusions: </strong>Student evaluation over a decade has driven continuous development of the programme. Our study demonstrates incremental changes have enriched the learning experience and preparedness for clinical practice.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasensitive multiplex salivary cytokine profiling reveals distinct immune signatures in dental caries.","authors":"Margaux Dubois, Morgane Ortis, Lilit Tonoyan, Emma Dubois, Marie-France Bertrand, Alain Doglio","doi":"10.1038/s41405-026-00475-4","DOIUrl":"10.1038/s41405-026-00475-4","url":null,"abstract":"<p><strong>Background: </strong>Dental caries is a prevalent chronic disease characterized by complex inflammatory responses in the oral environment. This case-control pilot study evaluated the analytical performance of an ultra-sensitive electrochemiluminescence multiplex assay (MSD S-PLEX^®) for salivary cytokine profiling and explored whether combined cytokine signatures can discriminate dental caries lesions (CL) from healthy (H) and non-carious gingival inflammation (GI).</p><p><strong>Methods: </strong>Unstimulated whole saliva from 65 individuals (H, CL, GI) was analyzed using the S-PLEX assay to quantify nine salivary cytokines (IL-1β, TNF-α, IL-6, IL-4, IL-10, IL-12p70, IFN-γ, IL-17, and IL-2). Group comparisons were performed using Mann-Whitney tests, and diagnostic performance was assessed by logistic regression and the area under the receiver operating characteristic curve.</p><p><strong>Results: </strong>The assay showed high sensitivity and reproducibility. Cytokine profiling revealed selective elevation of certain cytokines in saliva from CL. Among the models tested, TNF-α + IL-17 provided the best discrimination between CL and H (AUC = 0.901, p < 0.001) and between CL and H + GI (AUC = 0.795, p = 0.0003). Inclusion of additional cytokines did not improve performance. However, discrimination between CL and GI was limited with TNF-α + IL-17, while IL-1β + IL-17 provided a modest but significant discrimination (AUC = 0.737, p = 0.004).</p><p><strong>Conclusion: </strong>This proof-of-concept study demonstrated the feasibility of ultrasensitive multiplex salivary cytokine profiling using the S-PLEX platform and revealed distinct cytokine signatures associated with clinically detected carious lesions. While preliminary, these findings support further investigation of salivary host-response biomarkers in caries research. Future longitudinal studies integrating comprehensive clinical, microbial, and immunological data together with detailed clinical characterization, including radiographic assessment and lesion severity evaluation, will be necessary to validate these associations and clarify their potential biological and clinical significance in caries research and their potential role in personalized caries management.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13526018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and disparities in preventive oral health care in the UK: insights from oral health professionals and consumers surveys.","authors":"Michelle Wodke, Munisha Mangal, Alyson Axe, Billy Franks, Kate Fabrikant","doi":"10.1038/s41405-026-00477-2","DOIUrl":"10.1038/s41405-026-00477-2","url":null,"abstract":"<p><strong>Objective/aim: </strong>Preventive oral health care (POHC) is an integral aspect of overall health, yet oral health professionals (OHPs) frequently encounter challenges with patient adherence to preventive recommendations. This study aims to identify barriers to effective POHC implementation examining perspectives from both consumers and OHPs. Understanding these barriers will support targeted interventions to enhance public awareness and promote proactive oral health behaviours.</p><p><strong>Materials and methods: </strong>Two UK-wide research surveys were conducted to capture oral health habits and the integration of preventive advice during routine dental visits. The first survey targeted OHPs (n = 505) and consumers (n = 2000), exploring attitudes toward POHC and compliance. The second survey involved parents (n = 1004) and children (n = 1004) to assess parental influence on paediatric oral health practices.</p><p><strong>Results: </strong>Findings revealed notable variations in attitude towards POHC in consumers across demographics, including gender-based differences. Additionally, a misalignment between consumer expectations and OHPs perceptions was observed. Children and parent survey results further highlighted that parental awareness and attitudes substantially influenced children's preventive behaviours and confidence, with notable regional variations.</p><p><strong>Conclusion: </strong>This research highlights the need to involve both consumers and OHPs to improve POHC for better outcomes in oral health. There is an opportunity for the oral health industry to address the identified barriers through tailored consumer-facing educational campaigns and support relevant training programmes, ensuring that all OHPs are better equipped. These efforts could build a foundation for improved quality of life and lifelong oral health in the UK.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13507190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148819739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benchmarking Australian Dental Weighted Activity Units against public and private dental fee schedules: a cross-sectional item-code comparator study.","authors":"Jonathon Oddy, William Ha","doi":"10.1038/s41405-026-00479-0","DOIUrl":"https://doi.org/10.1038/s41405-026-00479-0","url":null,"abstract":"<p><strong>Objective: </strong>To benchmark Dental Weighted Activity Units (DWAUs) against Australian dental remuneration schedules and derive suggested recalibration factors for endodontics, periodontics and prosthodontics.</p><p><strong>Materials and methods: </strong>A cross-sectional item-code comparator study linked Australian Dental Association item codes to DWAU values and fees from public and private schedules, standardised to 1 January 2025 Australian dollars. The primary outcome was grouped DWAU per dollar, calculated as the sum of DWAUs divided by the sum of fees and expressed as DWAU per $1000. Lower values indicated fewer DWAUs credited per dollar of remuneration. Merged general and merged specialist fee series were constructed, with bootstrap 95% confidence intervals and suggested stream-specific calibration factors estimated.</p><p><strong>Results: </strong>Of 343 item codes, 264 had DWAU values greater than zero and 260 were included. Overall DWAU per $1000 was 1.589 for merged general comparators and 1.130 for merged specialist comparators. Under specialist comparators, endodontics had the lowest value at 0.945 DWAU per $1000, 16.40% below the benchmark. The suggested specialist calibration factor for endodontics was 1.196.</p><p><strong>Discussion: </strong>The findings indicate that current DWAU values are not uniformly aligned with remuneration signals, particularly for specialist endodontics, and supports stream-specific review rather than a single uniform adjustment.</p><p><strong>Conclusions: </strong>Cross-schedule benchmarking and specialist-adjusted DWAU rates may improve public dental activity measurement, commissioning and specialist service planning.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13486687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of extracellular vesicles derived from either blood or dental pulp stem cells on human dental pulp stem cells: an in vitro study.","authors":"Mona A Amer, Alaa M Mansour, Mohammed Grawish, Mazen Abou Elkhier","doi":"10.1038/s41405-026-00463-8","DOIUrl":"https://doi.org/10.1038/s41405-026-00463-8","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine and compare the possible proliferative and differentiative effects of extracellular vesicles (EVs) derived from human dental pulp stem cells (hDPSCs-EVs) and human blood plasma (hBP-EVs) on hDPSCs as an in-vitro assessment for their ability on endogenous hDPSCs for osteo-odontogenic differentiation MATERIALS AND METHODS: hDPSCs were isolated from impacted third molars of healthy donors and characterized by flow cytometry. EVs were isolated from hDPSCs-conditioned media and human plasma using differential ultracentrifugation and characterized by transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA), bicinchoninic acid assay (BCA), and Western blotting (WB). hDPSCs were cultured in standard medium (control) or supplemented with 50 µg/mL hDPSCs-EVs or hBP-EVs. Proliferation was assessed by MTT assay. Mineralization was evaluated by Alizarin Red staining. Odontogenic differentiation was analyzed by quantitative real-time PCR for dentin sialophosphoprotein (DSPP) expression and immunocytochemical detection of osteocalcin (OCN).</p><p><strong>Results: </strong>By flow cytometry, hDPSCs showed positive expression for CD90 and CD105 and negative expression for CD34 and CD45. Both EVs types demonstrated characteristic nanoscale morphology and EVs marker expression. hDPSCs-EVs significantly enhanced proliferation compared with hBP-EVs and control (P < 0.001). Additionally, mineral deposition, DSPP expression, and OCN-positive area were markedly higher in the hDPSCs-EVs group than in the hBP-EVs and control groups (P < 0.001).</p><p><strong>Conclusion: </strong>Although hBP-EVs exhibited measurable regenerative activity, tissue-specific hDPSCs- EVs produced significantly greater proliferative and osteo-odontogenic effects. These findings suggest that EVs bioactivity is strongly influenced by cellular origin and highlight the importance of lineage-specific vesicles in optimizing cell-free regenerative strategies for endodontic applications.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of sealing ability of Geristore and Mineral trioxide aggregate as root-end filling material in dry and saliva-contaminated environment.","authors":"Bibi Fatima, Farhan Raza Khan","doi":"10.1038/s41405-026-00474-5","DOIUrl":"https://doi.org/10.1038/s41405-026-00474-5","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the sealing capabilities of mineral trioxide aggregate (MTA) and Geristore as retrograde filling materials in dry and saliva-contaminated environments.</p><p><strong>Methodology: </strong>Seventy-two extracted single-rooted premolars were included. Root canals were prepared and obturated following decoronation. Each root's apical 3 mm was removed, and via ultrasonic tips, uniform retrograde cavities were created. The teeth were divided into four groups (n = 18) at random: MTA dry, MTA wet, Geristore dry, and Geristore wet. After that, samples were submerged in methylene blue dye (1%) for 48 h. A stereomicroscope was used to examine the longitudinally sectioned roots at a magnification of 25.6×. The linear penetration of dye was measured using ImageJ software. Tukey's post hoc test and one-way analysis of variance (ANOVA) were used in SPSS data analysis.</p><p><strong>Results: </strong>One-way ANOVA demonstrated a significant difference in dye penetration among the four groups (p < 0.001). In both dry (0.64 ± 0.42 mm) and wet (0.65 ± 0.32 mm) conditions, Geristore demonstrated similar sealing ability (p = 1.000). In contrast, MTA exhibited significantly lower dye penetration in dry conditions (0.47 ± 0.21 mm) than in wet conditions (1.13 ± 0.26 mm; p < 0.001), with the wet MTA group demonstrating the greatest microleakage.</p><p><strong>Conclusion: </strong>Geristore demonstrated consistent sealing ability irrespective of environmental conditions. Although MTA performed similarly in dry conditions, its sealing ability was significantly compromised by salivary contamination. Geristore may therefore be a more reliable root-end filling material when moisture control is difficult.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of post-resection maxillofacial defects on outcomes of 3D-printed prosthetic rehabilitation in oral cancer patients: a scoping review protocol.","authors":"Smitha Sammith Shetty, Shibani Shetty, Sameep S Shetty, Swapna Bv","doi":"10.1038/s41405-026-00476-3","DOIUrl":"10.1038/s41405-026-00476-3","url":null,"abstract":"<p><strong>Introduction: </strong>Oral cancer patients undergoing surgical resection often develop extensive maxillofacial defects that compromise function, aesthetics, and quality of life. Three-dimensional (3D) printing has enabled the development of customized, patient-specific prostheses, offering improved precision in rehabilitation. However, the extent to which defect type and location influence prosthetic outcomes remains inadequately synthesized in the current literature.</p><p><strong>Objective: </strong>To map and synthesize the available evidence on the impact of type of maxillofacial defect on outcomes of 3D-printed prostheses in oral cancer patients.</p><p><strong>Inclusion criteria: </strong>This review will include studies involving oral cancer patients with surgically acquired maxillofacial defects rehabilitated using a 3D-printed prosthesis. Studies involving intraoral and extraoral defects that report functional, clinical, prosthetic, or aesthetic outcomes of 3D-printed prostheses will be included.</p><p><strong>Methods: </strong>A comprehensive literature search will be conducted across databases including PubMed, Scopus, Web of Science, Embase, and Cochrane Library using relevant keywords. Two independent reviewers will perform study selection through title/abstract screening followed by full-text review. Data will be extracted using a structured template recording the study characteristics, surgical defect characteristics, prosthetic rehabilitation details, and outcome measures. Findings will be synthesized descriptively and presented in tabular and narrative formats to identify the research gaps. The review will be conducted and reported in accordance with the PRISMA-ScR guidelines.</p><p><strong>Review registration: </strong>Open Science Framework https://doi.org/10.17605/OSF.IO/C8STU.</p>","PeriodicalId":36997,"journal":{"name":"BDJ Open","volume":"12 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13476270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}