{"title":"Organic diode implementations in configurable architectures and temperature sensors","authors":"R. Ozgun, H. Katz, A. Andreou","doi":"10.1109/MAMNA.2013.6557231","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557231","url":null,"abstract":"In this paper, we report organic semiconductor based diodes, the silicon-on-insulator (SOI) integration technique with organic field effect transistors (OFET) for configurable diode arrays and sensors. We utilize the vertical organic diode approach, in which a layer of organic semiconductor (pentacene) is sandwiched between Au- and Al-electrodes such that one of the electrodes (Au) creates a homojunction with pentacene layer and permits the hole injection, on the other hand Al electrode and pentacene couple creates a heterojunction because of their work function difference and this junction blocks the injection of holes. Proposed design flow relies on only basic microfabrication processes such as photolithography and physical vapor deposition and the novel fabrication technique allows patterning of conductive silicon gate islands on the SOI subtrate and eases the via and interconnect patterning and deposition for a bottom-gate OFET configuration.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130353277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deepa Raghu, Q. Xia, Linwen Zhang, A. Vertes, M. Reeves
{"title":"In-vitro sub-cellular sampling of metabolites in biological samples","authors":"Deepa Raghu, Q. Xia, Linwen Zhang, A. Vertes, M. Reeves","doi":"10.1109/MAMNA.2013.6557232","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557232","url":null,"abstract":"Chemical analysis of metabolites directly from cell samples at sub-cellular level in ambient conditions is essential to understand the biochemical pathways in these organisms. In order to achieve this goal we combine near-field ablation with mass spectrometry. As a first step towards the integration of near-field ablation with mass spectrometry, we will report preliminary results of the chemical analysis of Arabidopsis Thaliana.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131019362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transfer-free, wafer-scale fabrication of graphene-based nanoelectromechanical resonators","authors":"M. Cullinan, J. Gorman","doi":"10.1109/MAMNA.2013.6557225","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557225","url":null,"abstract":"This paper presents a method for fabricating graphene-based nanoelectromechanical resonators at the wafer-scale using techniques that are compatibles with conventional MEMS manufacturing. In this method, graphene is grown directly on copper thin films using chemical vapor deposition. The graphene is then patterned and the copper is etched to create suspended graphene structures. This transfer-free fabrication method allows for precise fabrication of graphene resonators with localized back gates to minimize parasitic capacitances. This method also increase manufacturing flexability by allowing many different types of graphene devices to be fabricated on a single wafer.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128722910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subcellular near-field biomolecule sampling using a biosensor","authors":"Q. Xia, Adam S. Hughes, Deepa Raghu, M. Reeves","doi":"10.1109/MAMNA.2013.6557233","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557233","url":null,"abstract":"As the initial experiments towards integrating the near-field ablation and a fiber-optic biosensor, we report the near-field ablation on Arabidopsis thaliana leaf samples with a 2μm ablation spot. We also report time-dependent spectral plots of detecting biomolecules in the ground Arabidopsis leaf solution. The sensitivity of detecting biomolecules with amino functional groups was improved by using a biosensor coated with a specific type of cross linkers.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133636624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Fontana, Yian Liu, A. Monica, P. Barbara, M. Paranjape
{"title":"Influence of argon on field emission from CVD-grown in-plane single-walled carbon nanotube meshes","authors":"M. Fontana, Yian Liu, A. Monica, P. Barbara, M. Paranjape","doi":"10.1109/MAMNA.2013.6557226","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557226","url":null,"abstract":"The influence of argon (Ar) on the growth of in-plane single-walled carbon nanotube (SWCNTs) meshes using chemical vapor deposition (CVD) was investigated in this study. The SWCNT samples were synthesized using a three-zone furnace (750°C-900°C-750°C) with a methane/hydrogen/argon mixture (total flow of 60 sccm). We verified that the use of argon influences the diameter distribution and the field emission properties of the resulting SWCNTs. The threshold voltage for electron emission was significantly decreased with higher argon concentration due to higher layer conductivity of the samples.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121999563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fiberoptic nanobiosensor: A quantitative calibration method","authors":"Adam S. Hughes, M. Reeves, A. Matsko, Zhaowen Liu","doi":"10.1109/MAMNA.2013.6557228","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557228","url":null,"abstract":"A fiber optic nanobiosensor, with sensitivity comparable to commercial plasmonic sensors, a highly reduced sensing area, and the possibility of in-situ use is presented.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116534597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keshia E. Mora, Joshua D. Cohen, N. Morgan, Panpan Yu, H. M. Geller
{"title":"Microfluidic deposition of chondroitin sulfate proteoglycan surface gradients for neural cell culture","authors":"Keshia E. Mora, Joshua D. Cohen, N. Morgan, Panpan Yu, H. M. Geller","doi":"10.1109/MAMNA.2013.6557230","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557230","url":null,"abstract":"After injury, regeneration of the central nervous system (CNS) is inhibited by the secretion of repulsive guidance cues that mediate axon growth and guidance. These repulsive cues are perceived as spatial gradients of neurons. Microfluidic systems can enable studies of neuron response to spatial gradients, by generating precise and reproducible surface gradients of guidance cues. Understanding neuron response to these gradients could provide valuable information for therapies seeking to promote regeneration in the CNS. Here we report on the successful use of a microfluidic gradient generator to deposit spatially-extended and uniform surface gradients of one repulsive guidance cue, chondroitin sulfate proteoglycans (CSPGs). The patterned substrates are compatible with high-quality culture of large numbers of primary neurons, and initial findings indicate that neuron growth and guidance are responsive to the deposited CSPGs.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130176767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. R. Hood, E. Kendall, D. DeVoe, Z. Quezado, M. Junqueira, J. Finkel, W. Vreeland
{"title":"Microfluidic formation of nanoscale liposomes for passive transdermal drug delivery","authors":"R. R. Hood, E. Kendall, D. DeVoe, Z. Quezado, M. Junqueira, J. Finkel, W. Vreeland","doi":"10.1109/MAMNA.2013.6557227","DOIUrl":"https://doi.org/10.1109/MAMNA.2013.6557227","url":null,"abstract":"In this work, the established technique for microfluidic synthesis of nanoscale liposomes of tunable size has been exploited for preclinical studies investigating the ability of small liposomes to passively cross through dermal layers for transdermal drug delivery. Topical application of therapeutics provides an avenue for painless, noninvasive delivery of molecules aimed at a range of clinical conditions. Unlike traditional methods, which yield polydisperse liposomes too large to traverse dermal layers (typically >80 nm), the microfluidic method enables the first investigation of nearly-monodisperse liposomes which are within the size range of interest (approximately 40 nm and below) for passive transdermal drug delivery. Here, the microfluidic method for liposome production has been utilized to generate small, nearly-monodisperse liposomes and demonstrated size-dependent passive uptake into porcine dermal tissue.","PeriodicalId":369463,"journal":{"name":"2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129363348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}